Ukuhlolwa kwe-coomb okuqondile nokungaqondile: ukuthi kuyini nokuthi kwenzelwa ini

-Delile

• Kwenziwa kanjani ukuhlolwa
• Kusho ukuthini umphumela

Ukuhlolwa kwe-coomb luhlobo lokuhlolwa kwegazi oluhlola ubukhona bama-antibodies athile ahlasela amangqamuzana abomvu egazi, abangele ukubhujiswa kwawo futhi mhlawumbe aholele ekubonakaleni kohlobo lwe-anemia olwaziwa njenge-hemolytic.

Kunezinhlobo ezimbili eziyinhloko zalesi sivivinyo, ezibandakanya:

• Ukuhlolwa Kwama-Direct Coombs: ihlola ngqo amaseli abomvu egazi, ihlola amasosha omzimba anamathele engqamuzaneni elibomvu legazi nokuthi ngabe la ma-antibody atholakala yini kumasosha omzimba womuntu noma amukelwe ngokumpontshelwa. Lokhu kuhlolwa kuvame ukwenziwa ukuthola i-autoimmune hemolytic anemias - Bona ukuthi yiziphi izimpawu ezingakhombisa ukuthi kunesifo sokushoda kwegazi emzimbeni;
• Ukuhlolwa kwe-Coombs engaqondile: ihlola i-serum yegazi, ikhomba amasosha omzimba akhona lapho, futhi imvamisa iyacelwa ezimweni zokumpontshelwa, ukuqinisekisa ukuthi igazi elizonikelwa liyahambisana nomamukeli.

Ngaphezu kwe-anemia, lokhu kuhlolwa kungasiza futhi ekuboneni ezinye izifo ezithinta amangqamuzana egazi afana ne-leukemia, i-lupus, i-mononucleosis ne-fetal erythroblastosis, eyaziwa nangokuthi isifo se-hemolytic sosana olusanda kuzalwa, kanye nokukhomba ubungozi bokuthinteka kwegazi. Funda kabanzi nge-fetry erythroblastosis.

Kwenziwa kanjani ukuhlolwa

Ukuhlolwa kweCoombs kwenziwa kusampula yegazi, okumele iqoqwe elabhorethri yokuhlaziywa kwemitholampilo. Igazi eliqoqiwe lithunyelwa elabhorethri, lapho kuzokwenziwa khona ukuhlolwa okuqondile noma okungaqondile, ngokuya ngenhloso.

Ekuhlolweni okuqondile kweCoombs, i-reombenti yeCoombs yengezwa egazini lesiguli, ivumela ukubonwa kwama-antibody angaxhunyaniswa namaseli abomvu egazi. Ekuhlolweni okungaqondile kweCoombs, igazi liyaqoqwa futhi lihlukaniswe ngamasentimitha, lihlukanisa amaseli abomvu egazi ne-serum, equkethe amasosha omzimba. Ku-serum, kufakwa amaseli abomvu 'abhalwe kuqala' ngama-antibodies ukuze ahlole ukuthi ngabe kukhona yini ama-autoantibodies akhona ku-serum futhi, ngenxa yalokho, egazini lesiguli.

Ukwenza ukuhlolwa kweCoombs, akukho ukulungiselela okudingekayo, kepha eminye imishanguzo ingaphazamisa umphumela, ngakho-ke kubalulekile ukwazisa udokotela ngokusetshenziswa kwayo ukuze kunikezwe isiqondiso ngokumiswa kwayo.

Kusho ukuthini umphumela

Umphumela wokuhlolwa kwe-Coombs awuhle uma kungekho-antibody ebangela ukubhujiswa kwamaglobhu abomvu, yingakho kubhekwa njengomphumela ojwayelekile.

Kodwa-ke, uma umphumela ulungile, kusho ukuthi kukhona i-antibody egazini, ngakho-ke, uma umphumela ulungile ekuhloleni okuqondile kweCoombs kusho ukuthi umuntu angaba nesifo esinjengalesi:

• I-autoimmune hemolytic anemia;
• Ukutheleleka nge I-Mycoplasma sp.;
• Ugcunsula;
• Umdlavuza wegazi;
• I-Lupus erythematosus;
• I-Mononucleosis.

Endabeni yokuhlolwa okungaqondile kweCoombs, umphumela omuhle usho ukuthi umuntu une-antibody engadala amahlule lapho ethola olunye uhlobo lwegazi ngakho-ke, kuyadingeka ukuthi uqaphele lapho ufaka igazi.

Kunoma ikuphi, kuhlale kubalulekile ukuthi umphumela uhlolwe ngudokotela owucelile, ngoba isizinda esithile somuntu singawushintsha umphumela.