Ukuhlolwa kwe-Thyroxine (T4)

-Delile

• Yini ukuhlolwa kwe-thyroxine (T4)?
• Kusetshenziselwa ini?
• Kungani ngidinga ukuhlolwa kwe-thyroxine?
• Kwenzekani ngesikhathi sokuhlolwa kwe-thyroxine?
• Ngabe kukhona engizodinga ukukwenza ukulungiselela isivivinyo?
• Ingabe zikhona izingozi esivivinyweni?
• Isho ukuthini imiphumela?
• Ngabe kukhona okunye engidinga ukukwazi ngokuhlolwa kwe-thyroxine?
• Izinkomba

Yini ukuhlolwa kwe-thyroxine (T4)?

Ukuhlolwa kwe-thyroxine kusiza ukuxilonga ukuphazamiseka kwendlala yegilo. Indlala yegilo iyindlala encane emise okwevemvane etholakala eduze komphimbo. Indlala yegilo yakho yenza ama-hormone alawula indlela umzimba wakho osebenzisa ngayo amandla. Iphinde ibambe iqhaza elibalulekile ekulawuleni isisindo sakho, izinga lokushisa komzimba, amandla emisipha, kanye nemizwa yakho. I-Thyroxine, eyaziwa nangokuthi i-T4, uhlobo lwe-hormone yegilo. Lokhu kuhlolwa kukala izinga le-T4 egazini lakho. I-T4 eningi kakhulu noma encane kakhulu ingakhombisa isifo se-thyroid.

I-hormone ye-T4 iza ngezindlela ezimbili:

• Mahhala T4, ongena ezicutshini zomzimba lapho kudingeka khona
• Kuboshwe T4, enamathela emaprotheni, evimbela ukuthi angene ezicutshini zomzimba

Isivivinyo esilinganisa i-T4 yamahhala neyiboshiwe ibizwa ngokuthi ukuhlolwa okuphelele kwe-T4. Ezinye izivivinyo zikala nje i-T4 yamahhala. Ukuhlolwa kwamahhala kwe-T4 kubhekwa njengokunembe kakhulu kunokuhlolwa okuphelele kwe-T4 kokuhlola ukusebenza kwe-thyroid.

Amanye amagama: i-thyroxine yamahhala, i-T4 yamahhala, ingqikithi ye-T4 ephelele, isikrini se-thyroxine, ukuhlushwa kwamahhala kwe-T4

Kusetshenziselwa ini?

Ukuhlolwa kwe-T4 kusetshenziselwa ukuhlola ukusebenza kwe-thyroid nokuthola isifo se-thyroid.

Kungani ngidinga ukuhlolwa kwe-thyroxine?

Isifo se-thyroid sivame kakhulu kubantu besifazane futhi sivame ukwenzeka bengaphansi kweminyaka engama-40. Sibuye sithande ukusebenza emindenini. Ungadinga ukuhlolwa kwe-thyroxine uma ilungu lomndeni elike laba nesifo se-thyroid noma uma unezimpawu zokuba ne-hormone yegilo eningi egazini lakho, isimo esibizwa nge-hyperthyroidism, noma izimpawu zokuba nehomoni encane kakhulu ye-thyroid, isimo esibizwa nge-hypothyroidism.

Izimpawu ze-hyperthyroidism, ezaziwa nangokuthi i-thyroid engasebenzi ngokweqile, zifaka:

• Ukukhathazeka
• Ukwehla kwesisindo
• Ukuthuthumela ezandleni
• Ukunyuka kwenhliziyo
• Ukukhukhumeza
• Ukuqhuma kwamehlo
• Inkinga yokulala

Izimpawu ze-hypothyroidism, ezaziwa nangokuthi i-thyroid engasebenzi, zifaka:

• Ukuzuza kwesisindo
• Ukukhathala
• Ukulahleka kwezinwele
• Ukubekezelelana okuphansi kwamazinga okushisa abandayo
• Izikhathi zokuya esikhathini ezingajwayelekile
• Ukuqunjelwa

Kwenzekani ngesikhathi sokuhlolwa kwe-thyroxine?

Uchwepheshe wezempilo uzothatha isampula yegazi emthanjeni osengalweni yakho, esebenzisa inaliti encane. Ngemuva kokuthi kufakwe inaliti, kuzoqoqwa inani elincane legazi kufakwe ithubhu yokuhlola noma isitsha. Ungase uzizwe uluma kancane lapho inaliti ingena noma iphuma. Lokhu ngokuvamile kuthatha imizuzu engaphansi kwemihlanu.

Ngabe kukhona engizodinga ukukwenza ukulungiselela isivivinyo?

Awudingi amalungiselelo akhethekile wokuhlolwa kwegazi le-thyroxine. Uma umhlinzeki wakho wezokunakekelwa kwempilo eyalele ukuhlolwa okwengeziwe kusampula yegazi lakho, kungadingeka ukuthi uzile ukudla (ungadli noma uphuze) amahora ambalwa ngaphambi kokuhlolwa. Umhlinzeki wakho wezokunakekelwa kwempilo uzokwazisa uma ngabe kukhona imiyalelo ekhethekile ongayilandela.

Ingabe zikhona izingozi esivivinyweni?

Kunengozi encane kakhulu yokuhlolwa kwegazi. Ungaba nobuhlungu obuncane noma ukulimaza lapho kufakwe khona inaliti, kepha izimpawu eziningi ziyaphela ngokushesha.

Isho ukuthini imiphumela?

Imiphumela yakho ingahle ibe ngohlobo lwe-T4 ephelele, i-T4 yamahhala, noma inkomba yamahhala ye-T4.

• Inkomba yamahhala ye-T4 ifaka ifomula eqhathanisa i-T4 yamahhala neboshiwe.
• Amazinga aphezulu kwanoma yikuphi kwalokhu kuhlolwa (inani eliphelele le-T4, i-T4 yamahhala, noma inkomba yamahhala ye-T4) angabonisa i-thyroid engasebenzi ngokweqile, eyaziwa nangokuthi i-hyperthyroidism.
• Amazinga aphansi kwanoma yikuphi kwalokhu kuhlolwa (inani eliphelele le-T4, i-T4 yamahhala, noma inkomba yamahhala ye-T4) angabonisa i-thyroid engasebenzi, eyaziwa nangokuthi i-hypothyroidism.

Uma imiphumela yakho yokuhlolwa kwe-T4 ingejwayelekile, umhlinzeki wakho wezokunakekelwa kwempilo kungenzeka a-oda ezinye izivivinyo ze-thyroid ukusiza ukuxilonga. Lokhu kungafaka:

• Ukuhlolwa kwe-T3 hormone hormone. I-T3 ingenye i-hormone eyenziwe yi-thyroid.
• Ukuhlolwa kwe-TSH (thyroid stimulating hormone). I-TSH iyi-hormone eyenziwe ngendlala ye-pituitary. Kushukumisa i-thyroid ukukhiqiza ama-hormone e-T4 ne-T3.
• Ukuhlolwa kokuthola isifo se-Graves, isifo esizimele esibangela i-hyperthyroidism
• Uvivinyo lokuxilonga iHashimoto’s thyroiditis, isifo esizimele esibangela i-hypothyroidism

Funda kabanzi mayelana nokuhlolwa kwelabhorethri, ububanzi bezinkomba, nemiphumela yokuqonda.

Ngabe kukhona okunye engidinga ukukwazi ngokuhlolwa kwe-thyroxine?

Izinguquko ze-thyroid kungenzeka ngesikhathi sokukhulelwa. Yize kungavamile, abanye besifazane bangaba nesifo se-thyroid ngesikhathi sokukhulelwa. I-Hyperthyroidism yenzeka cishe ku-0.1% kuya ku-0.4% wokukhulelwa, kanti i-hypothyroidism yenzeka cishe ku-2.5% wokukhulelwa.

I-Hyperthyroidism, futhi kaningi, i-hypothyroidism, ingahlala ngemuva kokukhulelwa. Uma uba nesimo se-thyroid ngesikhathi ukhulelwe, umhlinzeki wakho wokunakekelwa kwezempilo uzoqapha isimo sakho ngemuva kokuzalwa kwengane yakho. Futhi, uma unomlando wesifo se-thyroid, qiniseka ukuthi ukhuluma nomhlinzeki wakho wezokunakekelwa kwezempilo uma ukhulelwe noma ucabanga ukukhulelwa.

Izinkomba

1. I-American Thyroid Association [i-Inthanethi]. ISonto LaseFalls (VA): I-American Thyroid Association; c2017. Izivivinyo Zomsebenzi We-thyroid [okushiwo ngo-2017 Meyi 22]; [cishe izikrini ezi-2]. Kutholakala kusuka: https://www.thyroid.org/thyroid-function-tests
2. UHinkle J, Cheever K. Brunner & Suddarth's Handbook of Laboratory and Diagnostic Test. 2^nd Ed, Kindle. IPhiladelphia: I-Wolters Kluwer Health, Lippincott Williams & Wilkins; c2014. I-Thryoxine, iSerum 485 k.
3. Ukuhlolwa Kwelebhu Ku-inthanethi [i-Intanethi]. IWashington DC: I-American Association for Clinical Chemistry; c2001–2017. I-T4 yamahhala: The Test [updated 2014 Oct 16; kukhonjiwe ngo-2017 Meyi 22]; [cishe izikrini ezi-4]. Kutholakala kusuka: https://labtestsonline.org/understanding/analytes/t4/tab/test
4. Ukuhlolwa Kwelebhu Ku-inthanethi [i-Intanethi]. IWashington DC: I-American Association for Clinical Chemistry; c2001–2017. I-T4 yamahhala: Isampula Yokuhlola [ibuyekezwe ngo-2014 Oct 16; kukhonjiwe ngo-2017 Meyi 22]; [cishe izikrini ezi-3]. Kutholakala kusuka: https://labtestsonline.org/understanding/analytes/t4/tab/sample
5. Ukuhlolwa Kwelebhu Ku-inthanethi [i-Intanethi]. IWashington DC: I-American Association for Clinical Chemistry; c2001–2017. I-TSH: Isampula Yokuhlola [ibuyekezwe ngo-2014 Oct 15; kukhonjiwe ngo-2017 Meyi 22]; [cishe izikrini ezi-3]. Kutholakala kusuka: https://labtestsonline.org/understanding/analytes/tsh/tab/sample
6. Uhlobo Lokuthengwa Kwamakhasimende we-Merck [Internet]. IKenilworth (NJ): IMerck & Co Inc .; c2017. Sibutsetelo se-Thyroid Gland [icashunwe ngo-2017 Meyi 22]; [cishe izikrini ezi-2]. Kutholakala kusuka: https://www.merckmanuals.com/home/hormonal-and-metabolic-disorders/thyroid-gland-disorders/overview-of-the-thyroid-gland
7. National Institute of Diabetes and Digestive and Kidney Diseases [i-Intanethi]. I-Bethesda (MD): UMnyango Wezempilo kanye Nezinsizakalo Zabantu e-U.S. Isifo Samathuna; 2012 Aug [icashunwe ngo-2017 Meyi 22]; [cishe izikrini ezi-3]. Kutholakala kusuka: https://www.niddk.nih.gov/health-information/endocrine-diseases/graves-disease
8. National Institute of Diabetes and Digestive and Kidney Diseases [i-Intanethi]. I-Bethesda (MD): UMnyango Wezempilo kanye Nezinsizakalo Zabantu e-U.S. Isifo sikaHashimoto; 2014 Meyi [kucashunwe ngo-2017 Meyi 22]; [cishe izikrini ezi-3]. Kutholakala kusuka: https://www.niddk.nih.gov/health-information/endocrine-diseases/hashimotos-disease
9. National Institute of Diabetes and Digestive and Kidney Diseases [i-Intanethi]. I-Bethesda (MD): UMnyango Wezempilo kanye Nezinsizakalo Zabantu e-U.S. Ukuhlolwa Kwendlala yegilo; 2014 Meyi [kucashunwe ngo-2017 Meyi 22]; [cishe izikrini ezi-3]. Kutholakala kusuka: https://www.niddk.nih.gov/health-information/diagnostic-tests/thyroid
10. I-National Heart, Lung, ne-Blood Institute [i-Intanethi]. I-Bethesda (MD): UMnyango Wezempilo kanye Nezinsizakalo Zabantu e-U.S. Ziyini Izingozi Zokuhlolwa Kwegazi? [kubuyekezwe 2012 Jan 6; kukhonjiwe ngo-2017 Meyi 22]; [cishe izikrini ezi-5]. Kutholakala kusuka: https://www.nhlbi.nih.gov/health-topics/blood-tests#Risk-Factors
11. I-National Heart, Lung, ne-Blood Institute [i-Intanethi]. I-Bethesda (MD): UMnyango Wezempilo kanye Nezinsizakalo Zabantu e-U.S. Ongakulindela Nezivivinyo Zegazi [kubuyekezwe ngo-2012 Jan 6; kukhonjiwe ngo-2017 Meyi 22]; [cishe izikrini ezi-4]. Kutholakala kusuka: https://www.nhlbi.nih.gov/health-topics/blood-tests
12. USoldin OP. Ukuhlolwa Komsebenzi We-Thyroid Ekukhulelweni Nasezifo Zesibindi: Izikhawu Eziqondene Nezikhombo Ze-Trimester. I-Ther Drug Monit. [Inthanethi]. I-2006 Feb [icashunwe ngo-2019 Juni 3]; 28 (1): 8-11. Kutholakala kusuka: https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3625634
13. I-University of Rochester Medical Center [i-Inthanethi]. URochester (NY): Isikhungo Sezokwelapha sase-University of Rochester; c2017. I-Health Encyclopedia: I-Free and Bound T4 [icashunwe ngo-2017 Meyi 22]; [cishe izikrini ezi-2]. Kutholakala kusuka: https://www.urmc.rochester.edu/encyclopedia/content.aspx?contenttypeid=167&contentid;=t4_free_and_bound_blood
14. I-University of Rochester Medical Center [i-Inthanethi]. URochester (NY): Isikhungo Sezokwelapha sase-University of Rochester; c2017. I-Health Encyclopedia: I-T4 yamahhala [icashunwe ngo-2017 Meyi 22]; [cishe izikrini ezi-2]. Kutholakala kusuka: https://www.urmc.rochester.edu/encyclopedia/content.aspx?contenttypeid=167&contentid=free_t4_thyroxine
    
    

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