Amakhambi amakhulu e-fibromyalgia

-Delile

• 1. Izidambisamagciwane
• 2. Imisipha ethambisa umzimba
• 3. I-Antiparkinsonian
• 4. Ama-painkillers
• 5. Ama-Neuromodulators
• 6. Ama-inducers okulala
• 7. Ama-anxiolytics

Izindlela zokwelapha i-fibromyalgia imvamisa ziyi-anti-depressants, njenge-amitriptyline noma i-duloxetine, izidambisi zemisipha, njenge-cyclobenzaprine, kanye nama-neuromodulators, njenge-gabapentin, ngokwesibonelo, enqunywe ngudokotela. Ngaphezu kwalokho, ezinye izindlela zokwelapha, njenge-aromatherapy, psychotherapy noma i-acupuncture, zingasiza ekwelashweni nasekusizeni ukulawula izimpawu. I-Physiotherapy ngokuzivocavoca nokubhucunga umzimba nayo ibalulekile ukusiza ukuqeda izinhlungu nokuvikela okunye ukuhlaselwa.

Ukwelashwa kwe-fibromyalgia kungokwemvelo futhi kusekelwe kuphela kwizimpawu, ngakho-ke kubalulekile ukuxhumana nodokotela wamathambo, udokotela wezinzwa noma wezifo zengqondo ukuhlola, ukuxilonga nokukhombisa ukwelashwa okungcono kakhulu. Thola ukwelashwa okungu-4 kwe-physiotherapy kwe-fibromyalgia.

1. Izidambisamagciwane

Izidambisi zikhonjiswa ekwelapheni i-fibromyalgia ngoba zisebenza ngqo ebuchosheni, zilawula izinto ezibalulekile ekusebenzeni kwayo, njenge-serotonin, i-norepinephrine ne-dopamine, ngaleyo ndlela kuthuthukiswe ubuhlungu, ukukhathala nokulala nokukhula kwemizwa. Izidakamizwa ezibekwe kakhulu ngudokotela yilezi:

• Amitriptyline (I-Tryptanol noma i-Amytril): isilinganiso sokuqala esinconywayo singu-10 mg nsuku zonke futhi kufanele sithathwe kusihlwa, amahora amabili kuya kwamathathu ngaphambi kokulala;

• I-Nortriptyline (I-Pamelor noma i-generic): kanye ne-amitriptyline, isilinganiso sokuqala esinconywayo singu-10 mg ngosuku futhi singakhuphuka kancane ngudokotela, uma kudingeka. I-capsule kufanele ithathwe ebusuku ngaphambi kokulala;

• I-Duloxetine (ICymbalta noma iVelija): imvamisa, umthamo wokuqala ungama-30 mg futhi ungakhuphuka ufike kuma-60 mg ngosuku ngokuya ngokuhlolwa kwezokwelapha;

• I-Fluoxetine (I-Prozac noma i-Daforin): ngomphumela omuhle, i-fluoxetine kufanele isetshenziswe ngemithamo ephezulu, ngaphezulu kwama-40 mg ngosuku, kepha ngudokotela kuphela ongahlola isilinganiso esizokhonjiswa;

• I-Moclobemide (I-Aurorix noma i-generic): umthamo wokuqala onconywayo ungama-300 mg nsuku zonke, uvame ukuhlukaniswa ngemithamo emibili futhi kufanele uthathwe ngemuva kokudla. Uma kunesidingo, umthamo ungakhuphuka kuze kufike kuma-600 mg ngosuku.

  
  

Umthamo wazo zonke izidambisi gciwane uhlukile futhi ukwelashwa kufanele kuqhubeke okungenani amasonto ama-4 kuye kwayi-6 ukufeza ukusebenza komuthi.

2. Imisipha ethambisa umzimba

I-relaxant yemisipha isetshenziselwa i-fibromyalgia ukunciphisa ukuqina kwemisipha eba lukhuni ibangele ubuhlungu emzimbeni wonke, ngaphezu kokuthuthukisa ukulala. Kulokhu, i-cyclobenzaprine iyisithako sokuphumuza imisipha esikhonjiswe ngudokotela futhi imithamo enconyiwe ingu-1 kuye ku-4 mg ebusuku kanti isikhathi sokwelashwa kufanele sibe amasonto amabili kuya kwamathathu.

3. I-Antiparkinsonian

Ama-Antiparkinsonia, okuyizidakamizwa zokwelapha amaParkinson's, njengepramipexole (Stabil noma iQuera), akhonjisiwe ukunciphisa ubuhlungu be-fibromyalgia nokwenza ngcono ukulala. Umthamo wokuqala onconywayo ungu-0.375 mg ngosuku, futhi umthamo ungakhuphuka kancane kancane ufike ku-1.50 mg ngosuku.

4. Ama-painkillers

Ama-painkillers alula afana ne-paracetamol (i-Tylenol noma i-generic) nama-opioid afana ne-tramadol (i-Tramal noma i-Novotram) anconywa ukuthi athuthukise ubuhlungu be-fibromyalgia. Lezi zinhlungu zingathathwa zodwa noma zingahlanganiswa ukuthola ukukhululeka kobuhlungu okungcono, njengoba zisebenza ezigabeni ezahlukahlukene ezibandakanyeka ebuhlungwini. Imithamo yale mithi kumele iqondiswe ngudokotela kanti i-tramadol ithengiswa kuphela ngodokotela.

5. Ama-Neuromodulators

Ama-Neuromodulators asebenza ngqo ohlelweni lwezinzwa, elawula izindlela ezibhekene nobuhlungu futhi, ngaleyo ndlela, anciphise ngempumelelo ubuhlungu obubangelwa yi-fibromyalgia. Le mithi ihlanganisa:

• UGabapentina (I-Neurontin noma iGabaneurin): kufanele ithathwe ngomlomo, kumthamo wokuqala ka-300 mg ngosuku, ongakhuphuka ufike kuma-900 mg kuye ku-3600 mg ngosuku;

• I-Pregabalin (ILyrica noma i-Insit): isilinganiso sokuqala esingu-75 mg ngomlomo, kabili ngosuku, okungukuthi, ama-150 mg ngosuku. Umthamo we-pregabalin ungakhuphuka kancane kancane, ngokusho kokuhlolwa kukadokotela, ufike kuma-450 mg ngosuku, uhlukaniswe ngemithamo emi-2.

Kokubili i-gabapentin ne-pregabalin kungathathwa ngaphambi noma ngemuva kokudla futhi kuthengiswa kuphela ngencwadi kadokotela. Kunconywa ukuthi umthamo wokuqala uthathwe ebusuku, ngesikhathi sokulala.

6. Ama-inducers okulala

Izinkinga zokulala zivamile ku-fibromyalgia, kokubili ukuqwasha nokungalali kahle. Ama-inducers wokulala ngokuvamile anconywa ukunciphisa lolu hlobo lokuphazamiseka futhi afaka:

• UZopiclone (Imovane): isilinganiso esinconywayo singeqi lethebulethi elilodwa elingu-7.5 mg ngomlomo ebusuku kanti ukwelashwa akufanele kweqe amasonto ama-4 ukugwema ukudala ukuncika;

• Zolpidem (I-Stilnox noma i-Zylinox): ithebhulethi ephezulu ye-1 mg 10 mg kufanele ithathwe ngomlomo ngaphambi kokulala, njengoba isebenza ngemuva kwemizuzu engama-30 ngemuva kokuthatha umthamo, futhi isikhathi sokwelashwa kufanele sibe sifushane ngangokunokwenzeka, singeqi amaviki ama-4.

Ama-inducers okulala asiza ukunciphisa ukungezwani kwemisipha okubangelwa ukungalali kahle futhi kuvame ukukhonjiswa ukulekelela ekwelapheni ubuhlungu be-fibromyalgia.

7. Ama-anxiolytics

I-Anxiolytics yizidakamizwa ezenza ukunciphisa ukukhathazeka, zibangela ukuphumula kwemisipha futhi zenze ukulala, kuthuthukise izimpawu ze-fibromyalgia. I-Anxiolytics kufanele isetshenziswe isikhathi esifushane ngenxa yekhono labo lokudala ukuluthwa futhi ifake:

• I-Lorazepam (I-Lorax noma i-Ansirax): inesikhathi esiphakathi somphumela wamahora ayi-10 kuye kwangama-20 futhi kufanele kuthathwe isilinganiso esisodwa sosuku se-1 kuye ku-2 mg, imvamisa ngesikhathi sokulala;

• I-Diazepam (I-Valium noma i-Uni-Diazepax): ubude bomphumela we-diazepam bude, ngamahora angama-44 kuye kwangama-48, kanti umthamo onconyiwe yi-1 tablet ka-5 kuye ku-10 mg ngomlomo, ebusuku, ongalungiswa ngokuya ngokuhlolwa kwezokwelapha.

Ukwelashwa nge-anxiolytics kufanele kuqale njalo ngomthamo ophansi kakhulu futhi kuhlale izinyanga ezi-2 kuya kwezi-3.

Ngaphezu kwemithi ethengwe ekhemisi, ezinye izindlela zokwelapha zasekhaya ezinjengamata neziphuzo zisiza ukudambisa izinhlungu ze-fibromyalgia futhi zinciphise ezinye izimpawu ezifana nokukhathala nokuphazamiseka kokulala. Funda kabanzi ngamakhambi asekhaya okwelashwa kwe-fibromyalgia.