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Kuyini ukuhlolwa kwe-tumor marker?

Lezi zivivinyo zibheka izimpawu zesimila, kwesinye isikhathi ezibizwa ngokuthi omaka bomdlavuza, egazini, emchameni noma ezicutshini zomzimba. Izimpawu zokumila yizinto ezenziwe ngamangqamuzana omdlavuza noma ngamaseli ajwayelekile ekuphenduleni umdlavuza emzimbeni. Ezinye izimpawu zesimila ziqondene nohlobo olulodwa lomdlavuza. Abanye bangatholakala ezinhlotsheni eziningana zomdlavuza.

Ngoba omaka besimila bangaphinde bavele ezimeni ezithile ezinganomdlavuza, ukuhlolwa kwesimila akuvamile ukusetshenziselwa ukuxilonga umdlavuza noma ukuhlola abantu abasengozini ephansi yalesi sifo. Lezi zivivinyo zivame ukwenziwa kubantu asebavele benomdlavuza. Izimpawu ze-tumor zingasiza ukuthola ukuthi umdlavuza wakho usakazekile yini, noma ngabe ukwelashwa kwakho kuyasebenza, noma uma umdlavuza wakho ubuyile ngemuva kokuqeda ukwelashwa.

Zisetshenziselwani?

Ukuhlolwa komaka we-tumor kuvame ukusetshenziselwa:

  • Hlela ukwelashwa kwakho. Uma amazinga we-tumor mark ehla, ngokuvamile kusho ukuthi ukwelashwa kuyasebenza.
  • Siza ukuthola ukuthi umdlavuza ususabalele kwezinye izicubu
  • Siza ukubikezela umphumela ongaba khona noma inkambo yesifo sakho
  • Hlola ukuthi umdlavuza wakho ubuyile yini ngemuva kokwelapha ngempumelelo
  • Hlaziya abantu abasengozini enkulu yomdlavuza. Izici zobungozi zingafaka umlando womndeni nokuxilongwa kwangaphambilini kolunye uhlobo lomdlavuza

Kungani ngidinga ukuhlolwa kwesimila?

Ungadinga ukuhlolwa kwesimila uma okwamanje welashelwa umdlavuza, usuqedile ukwelashwa komdlavuza, noma unengozi enkulu yokuthola umdlavuza ngenxa yomlando womndeni noma ezinye izizathu.


Uhlobo lokuhlolwa olutholayo luzoncika empilweni yakho, emlandweni wezempilo, nasezimpawu ongaba nazo. Ngezansi kunezinye zezinhlobo ezivame kakhulu zokumaka isimila nokuthi zisetshenziselwani.

CA 125 (umdlavuza antigen 125)
Isimila sesimila se:umdlavuza wesibeletho
Wawuvamise:
  • Bona ukuthi ukwelashwa komdlavuza kuyasebenza yini
  • Bona ukuthi umdlavuza ubuyile yini ngemuva kokuqeda ukwelashwa


I-CA 15-3 ne-CA 27-29 (ama-antigen womdlavuza 15-3 no-27-29)
Izimpawu zokumila ze:umdlavuza webele
Wawuvamise:Bheka ukwelashwa kwabesifazane abanomdlavuza webele osezingeni eliphakeme


I-PSA (i-antigen eqondene ne-prostate)
Isimila sesimila se:umdlavuza wendlala yabesilisa
Wawuvamise:
  • Isikrini somdlavuza wendlala yesinye
  • Siza ukuxilonga umdlavuza wendlala yabesilisa
  • Gada ukwelashwa
  • Bheka ukuthi umdlavuza ubuyile yini ngemuva kokuqeda ukwelashwa


I-CEA (carcinoembryonic antigen)
Isimila sesimila se:umdlavuza omhlophe, kanye nomdlavuza wamaphaphu, isisu, i-thyroid, amanyikwe, isifuba ne-ovary
Wawuvamise:
  • Bona ukuthi ukwelashwa komdlavuza kuyasebenza yini
  • Bona ukuthi umdlavuza ubuyile yini ngemuva kokuqeda ukwelashwa


I-AFP (i-Alpha-fetoprotein)
Isimila sesimila se:umdlavuza wesibindi, nomdlavuza we-ovary noma wamasende
Wawuvamise:
  • Siza ukuxilonga umdlavuza wesibindi
  • Thola ukuthi ngabe umdlavuza usakazekile (isigaba somdlavuza)
  • Bona ukuthi ukwelashwa komdlavuza kuyasebenza yini
  • Bikezela amathuba okululama


I-B2M (Beta 2-microglobulin)
Isimila sesimila se:ama-myeloma amaningi, amanye ama-lymphomas, nama-leukemias
Wawuvamise:
  • Bona ukuthi ukwelashwa komdlavuza kuyasebenza yini
  • Bikezela amathuba okululama


Kwenzekani ngesikhathi sokuhlolwa kwesimila?

Kunezindlela ezahlukahlukene zokuhlolela omaka isimila. Ukuhlolwa kwegazi uhlobo oluvame kakhulu lokuhlolwa komaka we-tumor. Ukuhlolwa komchamo noma ama-biopsies nakho kungasetshenziselwa ukubheka omaka be-tumor. I-biopsy inqubo encane ebandakanya ukususa ucezu oluncane lwezicubu ukuze kuhlolwe.


Uma uthola ukuhlolwa kwegazi, uchwepheshe wezokunakekelwa kwempilo uzothatha isampuli yegazi emthanjeni osengalweni yakho, esebenzisa inaliti encane. Ngemuva kokuthi kufakwe inaliti, kuzoqoqwa inani elincane legazi kufakwe ithubhu yokuhlola noma isitsha. Ungase uzizwe uluma kancane lapho inaliti ingena noma iphuma. Lokhu ngokuvamile kuthatha imizuzu engaphansi kwemihlanu.

Uma uthola ukuhlolwa komchamo, buza umhlinzeki wakho wezokunakekelwa kwempilo ngemiyalo yokuthi ungasinikeza kanjani isampula sakho.

Uma uthola i-biopsy, umhlinzeki wezempilo uzokhipha isiqeshana esincane sezicubu ngokusika noma ngokuklwebha isikhumba. Uma umhlinzeki wakho edinga ukuhlola izicubu ngaphakathi komzimba wakho, angasebenzisa inaliti ekhethekile ukukhipha isampula.

Ngabe kukhona engizodinga ukukwenza ukulungiselela isivivinyo?

Imvamisa awudingi amalungiselelo akhethekile wokuhlolwa kwegazi noma umchamo. Uma uthola i-biopsy, kungadingeka ukuthi uzile ukudla (ungadli noma uphuze) amahora ambalwa ngaphambi kwenqubo. Khuluma nomhlinzeki wakho wezempilo uma unanoma yimiphi imibuzo mayelana nokulungiselela ukuhlolwa kwakho.


Ingabe zikhona izingozi esivivinyweni?

Kunengozi encane kakhulu yokuhlolwa kwegazi. Ungaba nobuhlungu obuncane noma ukulimaza lapho kufakwe khona inaliti, kepha izimpawu eziningi ziyaphela ngokushesha.

Ayikho ingozi yokuhlolwa komchamo.

Uma uke waba ne-biopsy, ungahle ube nokulimala okuncane noma ukopha endaweni ye-biopsy. Ungase futhi ube nokungakhululeki okuncane esizeni usuku noma ezimbili.

Isho ukuthini imiphumela?

Ngokuya ngohlobo lokuhlolwa obe nalo nokuthi lusetshenziswe kanjani, imiphumela yakho inga:

  • Siza ukuxilonga uhlobo noma isigaba somdlavuza wakho.
  • Khombisa ukuthi ukwelashwa kwakho komdlavuza kuyasebenza yini.
  • Siza ukuhlela ukwelashwa kwesikhathi esizayo.
  • Khombisa ukuthi umdlavuza wakho ubuyile ngemuva kokuqeda ukwelashwa.

Uma unemibuzo ngemiphumela yakho, khuluma nomhlinzeki wakho wezokunakekelwa kwempilo.

Funda kabanzi mayelana nokuhlolwa kwelabhorethri, ububanzi bezinkomba, nemiphumela yokuqonda.

Ngabe kukhona okunye engidinga ukukwazi mayelana nokuhlolwa komaka we-tumor?

Omaka bezicubu bangasiza kakhulu, kepha imininingwane abayinikezayo ingakhawulelwa ngoba:

  • Ezinye izimo ezingezona umdlavuza zingadala izimpawu zesimila.
  • Abanye abantu abanomdlavuza abanazo izimpawu zesimila.
  • Akuzona zonke izinhlobo zomdlavuza ezinezimpawu zesimila.

Ngakho-ke, amamaki we-tumor cishe asetshenziswa njalo nokunye ukuhlolwa ukusiza ukuxilonga nokuqapha umdlavuza.

Izinkomba

  1. Cancer.Net [Inthanethi]. I-Alexandra (VA): I-American Society of Clinical Oncology; 2005-2018. Ukuhlolwa Kokumaka Kwe-tumor; U-2017 Meyi [ucashunwe ngo-2018 Eph 7]; [cishe izikrini ezi-4]. Kutholakala kusuka: https://www.cancer.net/navigating-cancer-care/diagnosing-cancer/tests-and-procedures/tumor-marker-tests
  2. UHinkle J, Cheever K. Brunner & Suddarth's Handbook of Laboratory and Diagnostic Test. 2nd Ed, Kindle. IPhiladelphia: I-Wolters Kluwer Health, Lippincott Williams & Wilkins; c2014. Ama-Cancer Tumor Markers (CA 15-3 [27, 29], CA 19-9, CA-125, ne-CA-50); 121 k.
  3. Ukuhlolwa Kwelebhu Ku-inthanethi [i-Intanethi]. IWashington DC: I-American Association for Clinical Chemistry; c2001–2018. I-Biopsy [ibuyekezwe ngo-2017 Jul 10; kukhonjiwe 2018 Eph 7]; [cishe izikrini ezi-2]. Kutholakala kusuka: https://labtestsonline.org/glossary/biopsy
  4. Ukuhlolwa Kwelebhu Ku-inthanethi [i-Intanethi]. IWashington DC: I-American Association for Clinical Chemistry; c2001–2018. Ama-Tumor Markers [abuyekezwe ngo-2018 Ephreli 7; kukhonjiwe 2018 Eph 7]; [cishe izikrini ezi-2]. Kutholakala kusuka: https://labtestsonline.org/tests/tumor-markers
  5. Uhlobo Lokuthengwa Kwamakhasimende we-Merck [Internet]. IKenilworth (NJ): IMerck & Co Inc .; c2018. Ukuxilongwa Komdlavuza [okushiwo ngo-2018 Ephreli 7]; [cishe izikrini ezi-2]. Kutholakala kusuka: https://www.merckmanuals.com/home/cancer/overview-of-cancer/diagnosis-of-cancer
  6. Isikhungo Somdlavuza Kazwelonke [i-Inthanethi]. I-Bethesda (MD): UMnyango Wezempilo kanye Nezinsizakalo Zabantu e-U.S. Izimpawu Zokumila [ezicashunwe ngo-2018 Ephreli 7]; [cishe izikrini ezi-4]. Kutholakala kusuka: https://www.cancer.gov/about-cancer/diagnosis-staging/diagnosis/tumor-markers-fact-sheet#q1
  7. I-National Heart, Lung, ne-Blood Institute [i-Intanethi]. I-Bethesda (MD): UMnyango Wezempilo kanye Nezinsizakalo Zabantu e-U.S. Ukuhlolwa Kwegazi [okushiwo ngo-2018 Ephreli 7]; [cishe izikrini ezi-3]. Kutholakala kusuka: https://www.nhlbi.nih.gov/health-topics/blood-tests
  8. I-Oncolink [Inthanethi]. IPhiladelphia: Abaphathiswa beYunivesithi yasePennsylvania; c2018. Umhlahlandlela Weziguli Wokumaka Kwezimila [kubuyekezwe ngo-2018 Mashi 5; kukhonjiwe 2018 Eph 7]; [cishe izikrini ezi-3]. Kutholakala kusuka: https://www.oncolink.org/cancer-treatment/procedures-diagnostic-tests/blood-tests-tumor-diagnostic-tests/patient-guide-to-tumor-markers
  9. I-University of Rochester Medical Center [i-Inthanethi]. URochester (NY): Isikhungo Sezokwelapha sase-University of Rochester; c2018. I-Health Encyclopedia: Ukuhlolwa KweLab Komdlavuza [okushiwo ngo-2018 Ephreli 7]; [cishe izikrini ezi-2]. Kutholakala kusuka: https://www.urmc.rochester.edu/encyclopedia/content.aspx?contenttypeid=85&contentid;=p07248
  10. Impilo ye-UW: Isibhedlela Sezingane Sezingane ZaseMelika [i-Intanethi]. UMadison (WI): Izibhedlela zase-University of Wisconsin kanye neGunya Lemitholampilo; c2018. Impilo Yezingane: I-Biopsy [icashunwe ngo-2018 Ephreli 7]; [cishe izikrini ezi-3]. Kutholakala kusuka: https://www.uwhealthkids.org/kidshealth/en/parents/biopsy.html/
  11. I-UW Health [Inthanethi]. UMadison (WI): Izibhedlela zase-University of Wisconsin kanye neGunya Lemitholampilo; c2018. Izimpawu Zokumila: Ukubuka konke kwesihloko [kubuyekezwe ngo-2017 Meyi 3; kukhonjiwe 2018 Eph 7]; [cishe izikrini ezi-2]. Kutholakala kusuka: https://www.uwhealth.org/health/topic/special/tumor-marker-tests/abq3994.html

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