Kuyini iHyperparathyroidism nokuthi ungayelapha kanjani

-Delile

• Izimpawu eziyinhloko
• Ungayixilonga kanjani
• Yelashwa kanjani

I-Hyperparathyroidism yisifo esibangela ukukhiqizwa ngokweqile kwe-hormone i-PTH, ekhishwe yizindlala ze-parathyroid, ezisentanyeni ngemuva kwe-thyroid.

Ihomoni i-PTH isiza ukugcina amazinga e-calcium egazini futhi, lokho, imiphumela yayo emikhulu ifaka ukubuyiselwa kwe-calcium ezinso, ukumuncwa okukhulu kwe-calcium ekudleni okusemathunjini, kanye nokususwa kwe-calcium egcinwe emathanjeni ukukhulula ungene egazini.

I-Hyperparathyroidism ingavela ngezindlela ezi-3:

• I-hyperparathyroidism eyinhloko: kwenzeka lapho isifo se-parathyroids uqobo sidala i-hypersecretion ye-hormone PTH, ikakhulu ngenxa ye-adenoma noma i-hyperplasia yalezi zindlala;
• I-hyperparathyroidism yesibili: kuvela ngenxa yokuphazamiseka kokugaya komzimba, okuvuselela izindlala ze-parathyroid, ikakhulukazi ngenxa yokuhluleka kwezinso, futhi okudala ukwehla kwamazinga e-calcium ne-phosphorus ekujikelezeni kwegazi;
• I-hyperparathyroidism ephakeme: akuvamile, kubonakala lapho izindlala ze-parathyroid ziqala ukukhipha i-PTH eyengeziwe zodwa, futhi zingavela ngemuva kwesikhathi esithile se-hyperparathyroidism yesibili, ngokwesibonelo.

Lapho ikhonjwa, i-hyperparathyroidism idinga ukwelashwa ngokushesha, ngoba ingaba nemiphumela emibi, njengokuncipha kwamathambo, ikhuphule ubungozi bokuqhekeka. Ngaphezu kwalokho, i-calcium eyeqile egazini nayo ingadala ushintsho ekusebenzeni kwemisipha, amatshe ezinso, ukukhuphuka kwengcindezi yegazi nezinye izinkinga zenhliziyo.

Lesi sifo siyelapheka lapho kwenziwa ukuhlinzwa ukuze kususwe indlala, kodwa-ke, ngaphambi kwalokho, kungakhonjiswa amakhambi angasetshenziswa ukulawula izimpawu.

Izimpawu eziyinhloko

Ezinye zezimpawu nezimpawu ezivame kakhulu ezimweni ze-hyperparathyroidism yilezi:

• Ithambo eliqinile futhi nengozi enkulu yokuqhekeka;
• Ubuthakathaka bemisipha;
• Ukuthuthukiswa kwamatshe ezinso;
• Isifiso esengeziwe sokuchama;
• Ubuhlungu obuqhubekayo esiswini;
• Ukukhathala ngokweqile;
• Ukuthuthukiswa kokuhluleka kwezinso noma i-pancreatitis;
• Ukucanuzela kwenhliziyo, ukuhlanza nokulahlekelwa isifiso sokudla.

I-Hyperparathyroidism ayibangeli zimpawu ngaso sonke isikhathi, ikakhulukazi lapho kusaqala, ngakho-ke kujwayelekile ukuthi lesi sifo sitholakale ekuhlolweni okuvamile kwegazi, okukhombisa ushintsho emazingeni e-calcium egazi.

Ungayixilonga kanjani

Ukuxilongwa kwe-hyperparathyroidism kwenziwa ngokulinganisa kwe-hormone PTH, eyanda kuzo zonke izinhlobo zesifo. Ngemuva kwalokho, udokotela we-endocrinologist uzo-oda ezinye izivivinyo ezisiza ukukhomba imbangela yenkinga, efana nomthamo we-calcium, ophakeme kakhulu ku-hyperparathyroidism eyinhloko futhi wehliswe kwesibili, ngaphezu kokuhlolwa okufana ne-calcium ne-phosphorus emchameni, isibonelo.

Ukuhlolwa kwe-Radiographic nakho kungasiza ekuboneni lesi sifo, ngoba sikhombisa amathambo ane-demineralization kanye ne-osteoporosis. Ezimweni esezithuthuke kakhulu, lokhu kuhlolwa kungakhombisa ukwakheka kokumbiwa nokwanda kwezicubu nemikhumbi emathanjeni, eyaziwa ngokuthi "yithumba elinsundu".

Ngaphezu kwalokho, ukuhlolwa kwezithombe zesifunda sentamo, nge-ultrasound, scintigraphy noma i-magnetic resonance imaging, ngokwesibonelo, kungasiza ekuboneni izinguquko kwizindlala ze-parathyroid.

Yelashwa kanjani

Isinyathelo sokuqala ekwelapheni i-hyperparathyroidism eyinhloko ukulungiswa kwamazinga e-calcium, okuthi, uma eguqulwa kakhulu, angaba imbangela enkulu yezimpawu. Ngalokhu, kunezinketho ezahlukahlukene, ezibandakanya ukushintshwa kwehomoni, ezenziwe ikakhulukazi kwabesifazane ngemuva kokunqamuka kokuya esikhathini, njengoba ukushintshwa kwamahomoni athile kusiza ekugcineni amazinga e-calcium emathanjeni. Izidakamizwa zeBisphosphonate, ngakolunye uhlangothi, ziyasiza ekwandiseni ukubekwa kwe-calcium emathanjeni, kunciphise i-calcium yamahhala egazini. Bheka ezinye izimbangela ze-calcium eyeqile egazini nokuthi uyelapha kanjani.

Ukuhlinzwa kungakhonjiswa nasendabeni ye-hyperparathyroidism eyinhloko, njengoba kususa izindlala ezithintekile, kuphulukise lesi sifo. Kodwa-ke, inezingozi ezithile njengokulimala kwezinzwa ezilawula izintambo zezwi noma ukwehla okuphawulekayo kwamazinga e-calcium.

Endabeni ye-hyperparathyroidism yesibili, kubalulekile ukwenza ukuqapha nokwelashwa okulungile kokuhluleka kwezinso, ukushintshwa kwamazinga kavithamini D ne-calcium ancishisiwe. Amakhambi we-calcimimetic anomthelela ofanayo ne-calcium, okwenza ukuthi izindlala zikhiqize ama-hormone amancane. Isibonelo sala makhambi yi-cinacalcete.