Izinzuzo ze-9 Zezempilo ze-Vitamin B6 (Pyridoxine)

-Delile

• 1. Kwangathi Kungathuthukisa Isimo Nokunciphisa Izimpawu Zokucindezeleka
• 2. Kwangathi Kungakhuthaza Impilo YeBongo Nokunciphisa Ingozi Ye-Alzheimer
• 3. Ingavimbela futhi Iphathe i-Anemia ngokusiza Ukukhiqizwa Kwe-hemoglobin
• 4. Kungaba Lusizo Ekwelapheni Izimpawu ze-PMS
• 5. Kungasiza Ekwelapheni Isicanucanu Ngesikhathi Sokukhulelwa
• 6. Kwangathi Kungavimbela Imithambo Eminyene Nokunciphisa Ubungozi Bezifo Zenhliziyo
• 7. Kungasiza Ukuvikela Umdlavuza
• 8. Kwangathi Kungakhuthazwa Impilo Yamehlo Nokuvimbela Izifo Zamehlo
• 9. Kungalapha Ukuvuvukala Okuhambisana Nesifo Samathambo
• Imithombo Yokudla kanye Nezithasiselo ze-Vitamin B6
• Imiphumela emibi engaba khona ye-Vitamin B6 Eningi Kakhulu
• Okusemqoka

UVitamin B6, owaziwa nangokuthi i-pyridoxine, uvithamini oncibilika emanzini umzimba wakho owudingayo ukuze wenze imisebenzi eminingana.

Kubalulekile kumaphrotheni, amafutha kanye ne-carbohydrate metabolism kanye nokwakhiwa kwamaseli abomvu egazi kanye nama-neurotransmitters (1).

Umzimba wakho awukwazi ukukhiqiza uvithamini B6, ngakho-ke kufanele uwuthole ekudleni noma kwizithasiselo.

Abantu abaningi bathola uvithamini B6 owanele ngokudla kwabo, kepha abantu abathile bangaba sengozini yokushoda.

Ukudla inani elanele likavithamini B6 kubalulekile empilweni efanele futhi kungavimbela nokwelapha izifo ezingamahlalakhona ().

Nazi izinzuzo ze-9 zezempilo zikavithamini B6, esekelwa yisayensi.

1. Kwangathi Kungathuthukisa Isimo Nokunciphisa Izimpawu Zokucindezeleka

Uvithamini B6 udlala indima ebalulekile ekulawulweni kwemizwelo.

Lokhu kungenxa yokuthi le vithamini iyadingeka ekwakheni ama-neurotransmitters alawula imizwa, kufaka phakathi i-serotonin, i-dopamine ne-gamma-aminobutyric acid (GABA) (3,,).

IVitamin B6 nayo ingadlala indima ekwehliseni amazinga aphezulu egazi e-amino acid homocysteine, axhumene nokudangala nezinye izinkinga zengqondo (,).

Ucwaningo oluningi lukhombisile ukuthi izimpawu ezicindezelayo zihlotshaniswa namazinga aphansi egazi nokutholwa kukavithamini B6, ikakhulukazi kubantu abadala asebekhulile abasengozini enkulu yokushoda ngamavithamini B (,,).

Ucwaningo olulodwa kubantu abadala asebekhulile abangama-250 luthole ukuthi amazinga egazi angenawo uvithamini B6 aphindaphinde amathuba okucindezeleka ().

Kodwa-ke, ukusebenzisa uvithamini B6 ukuvimbela noma ukwelapha ukudangala akuboniswanga ukuthi kuyasebenza (,).

Ucwaningo lweminyaka emibili olulawulwayo cishe emadodeni amadala angama-300 abengenakho ukucindezeleka ekuqaleni luthole ukuthi labo abathatha isengezo nge-B6, folate (B9) kanye ne-B12 bebengenamathuba amancane okuba nezimpawu zokudangala uma kuqhathaniswa neqembu le-placebo ().

Isifinyezo Amazinga aphansi kavithamini B6 kubantu abadala asebekhulile axhunyaniswe nokudangala, kepha ucwaningo alukhombisanga ukuthi i-B6 iyindlela yokwelapha ephumelelayo yokuphazamiseka kwemizwelo.

2. Kwangathi Kungakhuthaza Impilo YeBongo Nokunciphisa Ingozi Ye-Alzheimer

UVitamin B6 angadlala indima ekwenzeni ngcono ukusebenza kobuchopho nokuvimbela isifo i-Alzheimer's, kodwa ucwaningo luyaphikisana.

Ngakolunye uhlangothi, i-B6 inganciphisa amazinga aphezulu egazi e-homocysteine ​​angakhuphula ubungozi be-Alzheimer's (,,).

Ucwaningo olulodwa kubantu abadala abayi-156 abanamazinga aphezulu we-homocysteine ​​kanye nokukhubazeka okuncane kokuqonda kutholakale ukuthi ukuthatha imithamo ephezulu ye-B6, B12 ne-folate (B9) kwehle i-homocysteine ​​futhi kwanciphisa ukumosha kwezinye izifunda zobuchopho ezisengozini ye-Alzheimer's ().

Kodwa-ke, akucaci ukuthi ukwehla kwe-homocysteine ​​kuhumusha ekuthuthukisweni kokusebenza kobuchopho noma izinga eliphansi lokukhubazeka kwengqondo.

Isivivinyo esilawulwa ngokungahleliwe kubantu abadala abangaphezu kwama-400 abane-Alzheimer's's mild to modzulse's found that doses high of B6, B12 and folatehlile amazinga e-homocysteine ​​kodwa akuzange kwehle ukwehla kokusebenza kobuchopho uma kuqhathaniswa ne-placebo ().

Ngaphezu kwalokho, ukubuyekezwa kwezifundo eziyi-19 kuphethe ngokuthi ukwengeza nge-B6, B12 ne-folate kuphela noma ngokuhlangana akuzange kuthuthukise ukusebenza kobuchopho noma kwehlise ubungozi be-Alzheimer's ().

Ucwaningo oluningi olubheka umphumela wevithamini B6 kuphela kumazinga e-homocysteine ​​nokusebenza kobuchopho kuyadingeka ukuqonda kangcono indima yale vithamini ekuthuthukiseni impilo yobuchopho.

Isifinyezo I-Vitamin B6 ingavimbela ukwehla kokusebenza kobuchopho ngokunciphisa amazinga e-homocysteine ​​ahlotshaniswa nesifo i-Alzheimer's kanye nokukhubazeka kwememori. Kodwa-ke, izifundo azikukhombisi ukusebenza kwe-B6 ekwenzeni ngcono impilo yobuchopho.

3. Ingavimbela futhi Iphathe i-Anemia ngokusiza Ukukhiqizwa Kwe-hemoglobin

Ngenxa yendima yayo ekukhiqizeni i-hemoglobin, uvithamini B6 ungasiza ekuvikeleni nasekwelapheni i-anemia ebangelwa ukuntula ().

IHemoglobin yiprotheni eletha umoya-mpilo kumaseli akho. Uma une-hemoglobin ephansi, amaseli akho awatholi i-oxygen eyanele. Ngenxa yalokho, ungaqala ukuba ne-anemia futhi uzizwe ubuthakathaka noma ukhathele.

Ucwaningo luxhumanise amazinga aphansi kavithamini B6 ne-anemia, ikakhulukazi kwabesifazane abakhulelwe nabesifazane abaneminyaka yobudala bokubeletha (,).

Kodwa-ke, ukuntuleka kukavithamini B6 kucatshangwa ukuthi akuvamile kubantu abadala abaningi abaphilile, ngakho-ke kunocwaningo olulinganiselwe ekusebenziseni i-B6 ukwelapha i-anemia.

Ucwaningo olwenziwe kowesifazane oneminyaka engama-72 one-anemia ngenxa ye-B6 ephansi luthole ukuthi ukwelashwa ngohlobo olusebenzayo kakhulu lwevithamini B6 izimpawu ezithuthukisiwe ().

Olunye ucwaningo luthole ukuthi ukuthatha ama-75 mg wevithamini B6 nsuku zonke ngesikhathi sokukhulelwa kwehlisa izimpawu zokushoda kwegazi kwabesifazane abakhulelwe abangama-56 ababengaphenduli ekwelashweni nge-iron ().

Ucwaningo oluningi luyadingeka ukuqonda ukusebenza kwe-vitamin B6 ekwelapheni i-anemia kubantu ngaphandle kwalabo abasengozini enkulu yokushoda kwamavithamini B, njengabesifazane abakhulelwe kanye nabantu abadala

Isifinyezo Ukungatholi i-vitamin B6 eyanele kungaholela ku-hemoglobin ne-anemia ephansi, ngakho-ke ukwengeza ngale vithamini kungavimbela noma kuphathe lezi zinkinga.

4. Kungaba Lusizo Ekwelapheni Izimpawu ze-PMS

I-Vitamin B6 isetshenziselwe ukwelapha izimpawu ze-premenstrual syndrome, noma i-PMS, kufaka phakathi ukukhathazeka, ukudangala kanye nokucasuka.

Abaphenyi basola ukuthi i-B6 isiza ngezimpawu ezingokomzwelo ezihlobene ne-PMS ngenxa yendima yayo ekwakheni ama-neurotransmitters alawula imizwa.

Ucwaningo lwezinyanga ezintathu kwabesifazane abangaphezu kwama-60 be-premenopausal luthole ukuthi ukuthatha ama-50 mg wevithamini B6 nsuku zonke kuthuthukisa izimpawu ze-PMS zokudangala, ukucasuka nokukhathala ngama-69% ().

Kodwa-ke, abesifazane abathole i-placebo baphinde babika nezimpawu ezithuthukisiwe ze-PMS, okuphakamisa ukuthi ukusebenza kahle kwesengezo se-vitamin B6 kungenzeka bekungenxa yomphumela we-placebo ().

Olunye ucwaningo oluncane luthole ukuthi u-50 mg wevithamini B6 kanye no-200 mg we-magnesium ngosuku zinciphise kakhulu izimpawu ze-PMS, kufaka phakathi ukuguquguquka kwemizwelo, ukucasuka nokukhathazeka, esikhathini esisodwa sokuya esikhathini ().

Ngenkathi le miphumela ithembisa, ikhawulwa ngosayizi wesampula omncane nobude besikhashana. Ucwaningo olwengeziwe mayelana nokuphepha nokusebenza kahle kukavithamini B6 ekuthuthukiseni izimpawu ze-PMS kuyadingeka ngaphambi kokuba kwenziwe izincomo ().

Isifinyezo Olunye ucwaningo luye lwabonisa ukuthi imithamo ephezulu kavithamini B6 ingasebenza ekwehliseni ukukhathazeka nezinye izinkinga zemizwa ezihambisana ne-PMS ngenxa yendima yayo ekwakheni ama-neurotransmitters.

5. Kungasiza Ekwelapheni Isicanucanu Ngesikhathi Sokukhulelwa

UVitamin B6 usetshenziswe amashumi eminyaka ukwelapha isicanucanu nokuhlanza ngesikhathi sokukhulelwa.

Eqinisweni, kuyisithako ku-Diclegis, umuthi ovame ukwelashwa ukugula kwasekuseni ().

Abaphenyi abaqiniseki ngokuphelele ukuthi kungani uvithamini B6 esiza ngokugula kwasekuseni, kepha kungenzeka ngoba i-B6 eyanele idlala izindima eziningi ezibalulekile ekuqinisekiseni ukukhulelwa okunempilo ().

Ucwaningo olwenziwe kwabesifazane abangama-342 emavikini abo okuqala ayi-17 okukhulelwa luthole ukuthi ukwengezelwa nsuku zonke okungama-30 mg wevithamini B6 kunciphise kakhulu imizwa yokuhlanjululwa ngemuva kwezinsuku ezinhlanu zokwelashwa, kuqhathaniswa ne-placebo ().

Olunye ucwaningo luqhathanise umthelela wejinja novithamini B6 ekwehliseni iziqephu zesicanucanu nokuhlanza kwabesifazane abakhulelwe abangu-126. Imiphumela ikhombise ukuthi ukuthatha ama-75 mg we-B6 usuku ngalunye kunciphise isicanucanu nezimpawu zokuhlanza ngo-31% ngemuva kwezinsuku ezine ().

Lezi zifundo ziphakamisa ukuthi uvithamini B6 uyasebenza ekwelapheni ukugula kwasekuseni noma esikhathini esingaphansi kwesonto elilodwa.

Uma unentshisekelo yokuthatha i-B6 yokugula kwasekuseni, khuluma nodokotela wakho ngaphambi kokuqala noma iziphi izithasiselo.

Isifinyezo Izithako ze-Vitamin B6 ngemithamo ka-30-75 mg ngosuku zisetshenzisiwe njengokwelashwa okusebenzayo kwesicanucanu nokuhlanza ngesikhathi sokukhulelwa.

6. Kwangathi Kungavimbela Imithambo Eminyene Nokunciphisa Ubungozi Bezifo Zenhliziyo

UVitamin B6 angavikela imithambo evinjelwe futhi anciphise ingozi yesifo senhliziyo.

Ucwaningo lukhombisa ukuthi abantu abanamazinga aphansi egazi likavithamini B6 banengozi ephindwe kabili yokuthola isifo senhliziyo uma kuqhathaniswa nalabo abanamazinga aphezulu e-B6 ().

Lokhu kungenzeka ngenxa yendima ye-B6 ekwehliseni amazinga aphakeme e-homocysteine ​​ahambisana nezinqubo eziningana zezifo, kufaka phakathi isifo senhliziyo (,,).

Ucwaningo oluthile lwathola ukuthi amagundane angenawo uvithamini B6 anezinga eliphakeme legazi le-cholesterol futhi aqala izilonda ezingadala ukuvinjelwa kwemithambo ngemuva kokuvezwa ku-homocysteine, uma kuqhathaniswa namagundane anezinga elanele le-B6 ().

Ucwaningo lomuntu lubonisa nomphumela omuhle we-B6 ekuvimbeleni isifo senhliziyo.

Isilingo esilawulwa ngokungahleliwe kubantu abadala abangu-158 abaphilile ababenezingane zakubo ezinesifo senhliziyo bahlukanisa ababambiqhaza baba ngamaqembu amabili, elilodwa elathola ama-250 mg kavithamini B6 no-5 mg we-folic acid nsuku zonke iminyaka emibili kanti elinye lathola i-placebo ().

Iqembu elithathe i-B6 ne-folic acid belinamazinga aphansi e-homocysteine ​​kanye nokuhlolwa kwenhliziyo okungajwayelekile ngesikhathi sokuzivocavoca kuneqembu le-placebo, okubeka engcupheni ephansi yesifo senhliziyo ().

Isifinyezo I-Vitamin B6 ingasiza ekwehliseni amazinga aphezulu we-homocysteine ​​aholela ekunciphiseni kwemithambo. Lokhu kunganciphisa ingozi yesifo senhliziyo.

7. Kungasiza Ukuvikela Umdlavuza

Ukuthola uvithamini B6 owanele kunganciphisa ingozi yokuba nezinhlobo ezithile zomdlavuza.

Isizathu sokuthi i-B6 ingasiza ekuvikeleni umdlavuza asicaci, kodwa abacwaningi basola ukuthi kuhlobene namandla ayo okulwa nokuvuvukala okungaba nomdlavuza nezinye izimo ezingalapheki (,).

Ukubuyekezwa kwezifundo eziyi-12 kutholakale ukuthi kokubili ukudla okwanele kokudla kanye namazinga egazi e-B6 ahlotshaniswa nezingozi eziphansi zomdlavuza obala. Abantu abanamazinga aphezulu egazi ka-B6 babenengozi ecishe ibe ngama-50% yokuthola lolu hlobo lomdlavuza ().

Ucwaningo ngevithamini B6 nomdlavuza webele lukhombisa nokuhlangana phakathi kwamazinga anele egazi ka-B6 nokwehla kwengozi yesifo, ikakhulukazi kwabesifazane abangemva kokuya esikhathini ().

Kodwa-ke, ezinye izifundo zamazinga kavithamini B6 kanye nengozi yomdlavuza azitholanga ukuhlangana (,).

Ucwaningo oluningi olufaka ukuhlolwa okungahleliwe hhayi izifundo zokuhlola kuphela oludingekayo ukuhlola indima ngqo kavithamini B6 ekuvikeleni umdlavuza.

Isifinyezo Olunye ucwaningo lokuhlola lubonisa ukuxhumana phakathi kokudla okwanele kanye namazinga egazi kavithamini B6 nokwehla kwengozi yezinhlobo ezithile zomdlavuza, kepha kudingeka olunye ucwaningo.

8. Kwangathi Kungakhuthazwa Impilo Yamehlo Nokuvimbela Izifo Zamehlo

I-Vitamin B6 ingadlala indima ekuvikeleni izifo zamehlo, ikakhulukazi uhlobo lokulahleka kombono oluthinta abantu abadala asebekhulile ababizwa ngokuthi yi-age-related macular degeneration (AMD).

Izifundo zixhumanise amazinga aphezulu egazi okusabalalisa i-homocysteine ​​nengozi eyengeziwe ye-AMD (,).

Njengoba uvithamini B6 usiza ukunciphisa amazinga egazi aphakeme e-homocysteine, ukuthola i-B6 eyanele kunganciphisa ubungozi balesi sifo ().

Ucwaningo lweminyaka eyisikhombisa kochwepheshe bezempilo besifazane abangaphezu kwama-5,400 luthole ukuthi ukuthatha isithasiselo sansuku zonke sikavithamini B6, B12 kanye ne-folic acid (B9) kunciphise kakhulu ubungozi be-AMD ngo-35-40%, uma kuqhathaniswa ne-placebo ().

Yize le miphumela iphakamisa ukuthi i-B6 ingadlala indima ekuvikeleni i-AMD, kunzima ukusho ukuthi ngabe i-B6 iyodwa izonikeza izinzuzo ezifanayo.

Ucwaningo luye lwaxhumanisa amazinga egazi aphansi ka-vitamin B6 nezimo zamehlo ezivimba imithambo exhuma kwi-retina. Ucwaningo olulawulwayo kubantu abangaphezu kuka-500 luthole ukuthi amazinga egazi aphansi kakhulu e-B6 ayehlotshaniswa kakhulu nokuphazamiseka kwe-retinal ().

Isifinyezo Izithako ze-Vitamin B6 zinganciphisa ubungozi bokuwohloka kwe-macular okuhlobene nobudala (i-AMD). Ngokwengeziwe, amazinga wegazi anele we-B6 angavimbela izingqinamba ezithinta i-retina. Kodwa-ke, kudingeka olunye ucwaningo.

9. Kungalapha Ukuvuvukala Okuhambisana Nesifo Samathambo

I-Vitamin B6 ingasiza ekwehliseni izimpawu ezihambisana ne-rheumatoid arthritis.

Izinga eliphakeme lokuvuvukala emzimbeni okubangelwa i-rheumatoid arthritis lingaholela emazingeni aphansi kavithamini B6 (,).

Kodwa-ke, akucaci ukuthi ukwengeza nge-B6 kunciphisa ukuvuvukala kubantu abakulesi simo.

Ucwaningo lwezinsuku ezingama-30 kubantu abadala abangama-36 abane-arthritis ye-rheumatoid luthole ukuthi ama-50 mg wevithamini B6 nsuku zonke alungisa amazinga wegazi aphansi ka-B6 kepha awanciphisanga ukukhiqizwa kwama-molecule okuvuvukala emzimbeni ().

Ngakolunye uhlangothi, ucwaningo kubantu abadala abangama-43 abane-arthritis ye-rheumatoid ethathe u-5 mg we-folic acid eyedwa noma u-100 mg kavithamini B6 onama-5 mg we-folic acid nsuku zonke kukhombisile ukuthi labo abathole i-B6 banamazinga aphansi kakhulu ama-molecule ahlasela ukuvuvukala ngemuva Amaviki ayi-12 ().

Imiphumela ephikisanayo yalezi zifundo kungenzeka ukuthi ingenxa yomehluko kumthamo kavithamini B6 nobude bokufunda.

Ngenkathi kubonakala ukuthi imithamo ephezulu yamavithamini B6 izengezo ingahlinzeka ngezinzuzo ezilwa nokuvuvukala kubantu abane-arthritis ye-rheumatoid ngokuhamba kwesikhathi, kudingeka olunye ucwaningo.

Isifinyezo Ukuvuvukala okuhambisana nesifo samathambo kungehlisa amazinga egazi kavithamini B6. Ukwengeza ngamanani aphezulu we-B6 kungasiza ekulungiseni amaphutha futhi kunciphise ukuvuvukala, kepha kudingeka olunye ucwaningo ukuqinisekisa le miphumela.

Imithombo Yokudla kanye Nezithasiselo ze-Vitamin B6

Ungathola uvithamini B6 ekudleni noma kwizithasiselo.

Inani lamanje elinconywayo lamanje (i-RDA) le-B6 ngu-1.3-1.7 mg wabantu abadala abaneminyaka engaphezu kwengu-19. Abantu abadala abaningi abanempilo bangathola le mali ngokudla okunomsoco okubandakanya ukudla okunothe amavithamini-B6 njenge-turkey, ama-chickpeas, i-tuna, isalmon, amazambane ubhanana (1).

Izifundo eziqhakambisa ukusetshenziswa kukavithamini B6 ukuvimbela nokwelapha izingqinamba zezempilo zigxile kwizithasiselo kunemithombo yokudla.

Imithamo ka-30-250 mg kavithamini B6 ngosuku isetshenzisiwe ocwaningweni lwe-PMS, ukugula kwasekuseni nesifo senhliziyo (,,).

Lawa manani e-B6 aphezulu kakhulu kune-RDA futhi kwesinye isikhathi ahlanganiswa namanye amavithamini e-B. Kunzima ukuhlola ukuthi ukwanda kokudla kwe-B6 kusuka emithonjeni yokudla kunezinzuzo ezifanayo zezimo ezithile ezinikezwa yi-supplements.

Uma unentshisekelo yokuthatha izithasiselo zikavithamini B6 ukuvimbela noma ukubhekana nenkinga yezempilo, khuluma nomhlinzeki wakho wezokunakekelwa kwempilo mayelana nenketho ekufanele kakhulu. Ngaphezu kwalokho, funa isengezo esivivinywe ikhwalithi ngumuntu wesithathu.

Isifinyezo Abantu abaningi bangathola uvithamini B6 owanele ngokudla kwabo. Kwezinye izimo, ukuthatha inani eliphakeme levithamini B6 kusuka kwizithasiselo ngaphansi kokuqondisa kukadokotela kungaba usizo.

Imiphumela emibi engaba khona ye-Vitamin B6 Eningi Kakhulu

Ukuthola uvithamini B6 omningi kwizithasiselo kungadala imiphumela emibi.

Uvithamini B6 ubuthi akunakwenzeka ukuthi buvele emithonjeni yokudla ye-B6. Kungacishe kube nzima ukusebenzisa inani lezithako ezivela ekudleni kuphela.

Ukuthatha ngaphezu kuka-1 000 mg we-supplementary B6 ngosuku kungadala ukulimala kwemizwa nobuhlungu noma ukuba ndikindiki ezandleni noma ezinyaweni. Eminye yale miphumela emibi ibhalwe phansi ngemuva nje kuka-100-300 mg we-B6 ngosuku ().

Ngalezi zizathu, umkhawulo ophakeme obekezelelekayo kavithamini B6 ngu-100 mg ngosuku kubantu abadala (3,).

Inani le-B6 elisetshenziselwa ukuphatha izimo ezithile zezempilo alivamile ukudlula leli nani. Uma unentshisekelo yokuthatha okungaphezu komkhawulo ongaphezulu obekezelelekayo, thintana nodokotela wakho.

Isifinyezo Uvithamini B6 omningi ovela kwizithasiselo ungadala ukulimala kwezinzwa nemikhawulo ngokuhamba kwesikhathi. Uma unentshisekelo yokuthatha isengezo se-B6, khuluma nomhlinzeki wakho wezokunakekelwa kwezempilo mayelana nokuphepha nomthamo.

Okusemqoka

UVitamin B6 uvithamini oncibilikiswa ngamanzi otholakala ekudleni noma kwizithasiselo.

Iyadingeka ezinkambisweni eziningi emzimbeni wakho, kufaka phakathi ukudala ama-neurotransmitters nokulawula amazinga we-homocysteine.

Izilinganiso eziphakeme ze-B6 zisetshenziselwe ukuvimbela noma ukwelapha izimo ezithile zezempilo, kufaka phakathi i-PMS, ukwehla okuhlobene nobudala be-macular (AMD) kanye nesicanucanu nokuhlanza ngesikhathi sokukhulelwa.

Ukuthola i-B6 eyanele ngokudla kwakho noma isengezo kubalulekile ukuze uhlale uphilile futhi ungaba nezinye izinzuzo zezempilo ezihlaba umxhwele.