I-Zytiga (abiraterone): iyini, yenzelwe ini nokuthi isetshenziswa kanjani

-Delile

• Yenzelwe ini
• Isetshenziswa kanjani
• Imiphumela emibi engaba khona
• Ubani okungafanele athathe

I-Zytiga ngumuthi osetshenziswa ekwelapheni umdlavuza we-prostate one-abiraterone acetate njengesithako sayo esisebenzayo. I-Abiraterone ivimbela into edingekayo ekukhiqizeni ama-hormone alawula izici zesilisa, kepha futhi ahlobene nokwanda komdlavuza. Ngakho-ke, lo muthi uvimbela ukuqhubeka kwesimila ku-prostate, okwandisa iminyaka yokuphila.

Yize i-abiraterone kaZytiga ibangela ukuthi izindlala ze-adrenal zikhiqize inani elikhulu le-corticosteroids yemvelo, kujwayelekile ukuthi udokotela ancome nezidakamizwa ze-corticosteroid ndawonye, ​​ukusiza ukwehlisa ukuvuvukala kwendlala futhi kuthuthukise nezimpawu, njengokuchama kanzima noma umuzwa wesinye, isibonelo.

Lo muthi utholakala kumathebulethi angama-250 mg kanti intengo yawo emaphakathi ingu-10 kuye ku-15 wezinkulungwane ze-reais ngephakeji ngalinye, kepha futhi lifakiwe ohlwini lwezidakamizwa ze-SUS.

Yenzelwe ini

I-Zytiga ikhonjisiwe ekwelapheni umdlavuza wendlala yabesilisa emadodeni amadala lapho umdlavuza usakazeka emzimbeni wonke. Ingasetshenziswa futhi emadodeni angakazithuthukisi izifo zawo ngemuva kokuthena ukucindezela ukukhiqizwa kwamahomoni ezocansi noma ngemuva kwe-chemotherapy ne-docetaxel.

Isetshenziswa kanjani

Ungayisebenzisa kanjani i-Zytiga iqukethe ukuthatha amaphilisi angama-4 250 mg ngomthamo owodwa, cishe amahora amabili ngemuva kokudla. Akukho kudla okufanele kudliwe okungenani ihora elilodwa ngemuva kokusetshenziswa. Ungadluli umthamo wansuku zonke ophakeme we-1000 mg.

I-Zytiga ivame ukuthathwa ihlanganiswe no-5 noma 10 mg we-prednisone noma i-prednisolone, kabili ngosuku, ngokuyalelwa ngudokotela.

Imiphumela emibi engaba khona

Ukusetshenziswa kwalo muthi kungaholela ekubonakaleni kweminye imiphumela emibi, okuvame kakhulu ukuhlanganisa lokhu:

• Ukuvuvukala kwemilenze nezinyawo;
• Ukutheleleka kwe-Urinary;
• Ukwanda komfutho wegazi;
• Amazinga akhuphukayo amafutha egazini;
• Ukunyuka kwenhliziyo;
• Ubuhlungu besifuba;
• Izinkinga zenhliziyo;
• Uhudo;
• Amabala abomvu esikhunjeni.

Kungabuye kube nokuncipha kwamazinga e-potassium emzimbeni, okuholele ekubukekeni kobuthakathaka bemisipha, amajaqamba kanye nokushaya kwenhliziyo.

Ngokuvamile, lo muthi usetshenziswa ngokuqapha kukadokotela noma uchwepheshe wezempilo, njengomhlengikazi, ozoqaphela ukubonakala kwanoma iyiphi yale miphumela, aqale ukwelashwa okufanele, uma kunesidingo.

Ubani okungafanele athathe

I-Zytiga iyaphikiswa kubantu abane-hypersensitive to abiraterone noma enye ingxenye yefomula, kanye neziguli ezinokwehluleka okukhulu kwesibindi. Akufanele inikezwe abesifazane abakhulelwe noma ngenkathi ibele.