Ubisi lwe-Milk-alkali

I-Milk-alkali syndrome yisimo lapho kunezinga eliphezulu le-calcium emzimbeni (i-hypercalcemia). Lokhu kubangela ukushintsha kwe-acid / base balance yomzimba iye ku-alkaline (metabolic alkalosis). Ngenxa yalokhu, kungaba nokulahleka kokusebenza kwezinso.

I-Milk-alkali syndrome ivame ukubangelwa ukuthatha izithasiselo eziningi kakhulu ze-calcium, imvamisa iba se-calcium carbonate. I-calcium carbonate iyisengezo esivamile se-calcium. Kuvame ukuthathwa ukuvimbela noma ukwelapha ukulahleka kwethambo (i-osteoporosis). I-calcium carbonate nayo iyisithako esitholakala kuma-antacids (njengamaTum).

Izinga eliphakeme levithamini D emzimbeni, njengokuthatha izithasiselo, lingaqinisa ubisi-alkali syndrome.

Ukufakwa kwe-calcium ezinso nakwezinye izicubu kungenzeka ku-milk-alkali syndrome.

Ekuqaleni, isimo ngokuvamile asinazimpawu (asymptomatic). Lapho izimpawu zenzeka, zingabandakanya:

• Emuva, maphakathi nomzimba, nobuhlungu obuphansi emuva endaweni yezinso (ehlobene namatshe ezinso)
• Ukudideka, isimilo esingajwayelekile
• Ukuqunjelwa
• Ukucindezeleka
• Ukuchama ngokweqile
• Ukukhathala
• Ukushaya kwenhliziyo okungajwayelekile (arrhythmia)
• Isicanucanu noma ukuhlanza
• Ezinye izinkinga ezingabangelwa ukwehluleka kwezinso

Ukufakwa kwe-calcium ngaphakathi kwezicubu zezinso (nephrocalcinosis) kungabonakala ku:

• Ama-X-ray
• Iskena se-CT
• I-Ultrasound

Ezinye izivivinyo ezisetshenziselwa ukuxilonga zingabandakanya:

• Amazinga e-Electrolyte ukuhlola amazinga amaminerali emzimbeni
• I-Electrocardiogram (ECG) yokuhlola umsebenzi kagesi wenhliziyo
• I-Electroencephalogram (EEG) ukukala umsebenzi kagesi wobuchopho
• Izinga lokuhlunga le-Glomerular (GFR) ukuhlola ukuthi izinso zisebenza kahle kangakanani
• Izinga le-calcium yegazi

Ezimweni ezinzima, ukwelashwa kubandakanya ukufaka uketshezi ngomthambo (nge-IV). Ngaphandle kwalokho, ukwelashwa kubandakanya ukuphuza uketshezi kanye nokunciphisa noma ukumisa izithasiselo ze-calcium nama-antacids aqukethe i-calcium. Izithako ze-Vitamin D nazo zidinga ukwehliswa noma ukumiswa.

Lesi simo sivame ukubuyiselwa emuva uma ukusebenza kwezinso kuhlala kuyinto ejwayelekile. Amacala amade asele isikhathi eside angaholela ekuhlulekeni kwezinso unomphela okudinga i-dialysis.

Izinkinga ezivame kakhulu zifaka:

• Ukufakwa kwe-calcium ezicutshini (i-calcinosis)
• Ukuhluleka kwezinso
• Amatshe ezinso

Xhumana nomhlinzeki wakho wezempilo uma:

• Uthatha izithasiselo eziningi ze-calcium noma uvame ukusebenzisa ama-antacids aqukethe i-calcium, njenge-Tums. Ungahle udinge ukuthi uhlolwe i-milk-alkali syndrome.
• Unezimpawu ezingaphakamisa izinkinga zezinso.

Uma usebenzisa ama-antiacid aqukethe i-calcium kaningi, tshela umhlinzeki wakho ngezinkinga zokugaya ukudla. Uma uzama ukuvimbela i-osteoporosis, ungathathi ngaphezu kuka-1.2 amagremu (1200 milligrams) we-calcium ngosuku ngaphandle kwalapho uyalelwa ngumhlinzeki wakho.

Isifo se-calcium-alkali; I-Cope syndrome; Isifo seBurnett; I-Hypercalcemia; I-calcium metabolism disorder

I-Bringhurst FR, iDemay MB, iKronenberg HM. AmaHormoni nokuphazamiseka kwesimo semaminerali. Ku: Melmed S, Auchus RJ, Goldfine AB, Koenig RJ, Rosen CJ, abahleli. Incwadi kaWilliams ye-Endocrinology. Umhlaka 14. IPhiladelphia, PA: Elsevier; 2020: isahluko 29.

I-DuBose TD. I-alkalosis yomzimba. Ku: Gilbert SJ, Weiner DE, ama-eds. I-National Kidney Foundation Primer yezifo zezinso. Umhla wesi-7. IPhiladelphia, PA: Elsevier; 2018: isahluko 14.