I-Ankylosing spondylitis

I-Ankylosing spondylitis (AS) iyindlela engapheli yesifo samathambo. Kakhulu kuthinta amathambo namalunga ezansi yomgogodla lapho ihlangana khona nesinqe. La malungu angavuvukala futhi avuvuke. Ngokuhamba kwesikhathi, amathambo omgogodla athintekile angahlangana.

NJENGOBA ilungu eliyinhloko lomndeni wezinhlobo ezifanayo zesifo samathambo esibizwa nge-spondyloarthritis. Amanye amalungu afaka i-psoriatic arthritis, i-arthritis yesifo samathumbu esivuthayo kanye ne-arthritis esebenzayo. Umndeni wesifo samathambo ubonakala ujwayelekile futhi uthinta umuntu oyedwa kwabayikhulu.

Imbangela ye-AS ayaziwa. Izakhi zofuzo zibonakala zidlala indima. Iningi labantu abane-AS liqinisekile ngofuzo lwe-HLA-B27.

Lesi sifo sivame ukuqala phakathi kweminyaka engama-20 nengama-40, kepha singaqala singakabi neminyaka eyi-10. Sithinta abesilisa abaningi kunabesifazane.

NJENGOBA kuqala ngobuhlungu obuphansi emuva obuza futhi buhambe. Ubuhlungu obuphansi emuva buba khona isikhathi esiningi njengoba isimo siqhubeka.

• Ubuhlungu nokuqina kubi kakhulu ebusuku, ekuseni, noma uma ungasebenzi kakhulu. Ukungakhululeki kungakuvusa ebuthongweni.
• Ubuhlungu buvame ukuba ngcono ngomsebenzi noma ngokuzivocavoca umzimba.
• Ubuhlungu bokubuyela emuva bungaqala phakathi kwesikhumba nomgogodla (amalunga we-sacroiliac). Ngokuhamba kwesikhathi, kungabandakanya konke noma ingxenye yomgogodla.
• Umgogodla wakho ongezansi ungancipha kakhulu. Ngokuhamba kwesikhathi, ungema endaweni ebheke phambili.

Ezinye izingxenye zomzimba wakho ezingathinteka zifaka:

• Amalunga amahlombe, amadolo namaqakala, okungenzeka avuvuke futhi abe buhlungu
• Amalunga aphakathi kwezimbambo zakho nesifuba sakho, ukuze ungakwazi ukunweba isifuba sakho ngokugcwele
• Iso, elingaba nokuvuvukala nokubomvu

Ukukhathala nakho kuyisifo esivamile.

Izimpawu ezingavamile kakhulu zifaka:

• Umkhuhlane omncane

I-AS ingenzeka nezinye izimo, njenge:

• I-Psoriasis
• I-ulcerative colitis noma isifo seCrohn
• Ukuvuvukala kwamehlo okuphindaphindiwe noma okungapheli (iritis)

Ukuhlolwa kungafaka:

• I-CBC
• I-ESR (isilinganiso sokuvuvukala)
• I-HLA-B27 antigen (ethola isakhi sofuzo esixhunyaniswe ne-ankylosing spondylitis)
• Isici se-rheumatoid (okufanele singabi naso)
• Ama-X-ray womgogodla nokhalo
• I-MRI yomgogodla kanye ne-pelvis

Umhlinzeki wakho wezokunakekelwa kwempilo angakunikeza imithi efana nama-NSAID ukunciphisa ukuvuvukala nobuhlungu.

• Amanye ama-NSAID angathengwa ngaphezu kwe-counter (OTC). Lokhu kufaka phakathi i-aspirin, ibuprofen (Advil, Motrin), ne-naproxen (Aleve, Naprosyn).
• Amanye ama-NSAID anqunywe ngumhlinzeki wakho.
• Khuluma nomhlinzeki wakho noma usokhemisi ngaphambi kokusebenzisa isikhathi eside nsuku zonke kwanoma iyiphi i-NSAID engaphezulu kwe-counter.

Ungadinga futhi nemithi enamandla ukulawula izinhlungu nokuvuvukala, njenge:

• Ukwelashwa kwe-Corticosteroid (njenge-prednisone) esetshenziselwa isikhathi esifushane
• I-Sulfasalazine
• I-biologic TNF-inhibitor (njenge-etanercept, adalimumab, infliximab, certolizumab noma i-golimumab)
• I-biologic inhibitor ye-IL17A, secukinumab

Ukuhlinzwa, njengokufakwa esikhundleni se-hip, kungenziwa uma ubuhlungu noma ukulimala okuhlangene kunzima.

Ukuzivocavoca umzimba kungasiza ekuthuthukiseni ukuma komzimba nokuphefumula. Ukulala phansi ngomhlane ebusuku kungakusiza ugcine ukuma okujwayelekile.

Inkambo yalesi sifo kunzima ukubikezela. Ngokuhamba kwesikhathi, izimpawu nezimpawu ze-AS flareup (ebuyela emuva) nokuthula (ukuxolelwa). Iningi labantu liyakwazi ukusebenza kahle ngaphandle kokuthi libe nomonakalo omkhulu ezinqeni noma emgogodleni. Ukujoyina iqembu labasekeli labanye abanenkinga efanayo kungasiza.

Ukwelashwa nge-NSAIDS kuvame ukunciphisa ubuhlungu nokuvuvukala. Ukwelashwa ngama-TNF inhibitors ekuqaleni kwalesi sifo kubonakala kunciphisa ukukhula kwe-arthritis yomgogodla.

Ngokuvamile, abantu abane-ankylosing spondylitis bangaba nezinkinga nge:

• I-Psoriasis, isifo esingapheli sesikhumba
• Ukuvuvukala esweni (iritis)
• Ukuvuvukala emathunjini (colitis)
• Isigqi senhliziyo esingajwayelekile
• Ukuqhuma noma ukuqina kwezicubu zamaphaphu
• Ukuqhuma noma ukuqina kwe-aortic heart valve
• Ukulimala komgogodla ngemuva kokuwa

Shayela umhlinzeki wakho uma:

• Unezimpawu ze-ankylosing spondylitis
• Une-ankylosing spondylitis futhi uthuthukisa izimpawu ezintsha ngesikhathi sokwelashwa

I-spondylitis; I-spondyloarthritis; I-HLA - Spondylitis

• Umgogodla wamathambo
• I-spondylosis yomlomo wesibeletho

IGardocki RJ, iPaki AL. Ukuphazamiseka okwehlayo komgogodla we-thoracic ne-lumbar. Ku: Azar FM, Beaty JH, Kanale ST, ama-eds. I-Operational Orthopedics yaseCampbell. Umhlaka 13. IPhiladelphia, PA: Elsevier; 2017: isahluko 39.

Inman RD. Ama-spondyloarthropathies. Ku: IGoldman L, iSchafer AI, ama-eds. Imithi yeGoldman-Cecil. Umhla ka-26. IPhiladelphia, PA: Elsevier; 2020: isahluko 249.

van der Linden S, Brown M, Gensler LS, Kenna T, Maksymowych WP, Taylor WJ. I-Ankylosing spondylitis nezinye izinhlobo ze-axial spondyloarthritis. Ku: Firestein GS, Budd RC, Gabriel SE, Koretzky GA, McInnes IB, O'Dell JR, abahleli. Incwadi kaFirestein & Kelly yeRheumatology. Umhla ka-11. IPhiladelphia, PA: Elsevier; 2021: isahluko 80.

UWard MM, uDeodhar A, uGensler LS, et al. Ukuvuselelwa kwe-2019 kwe-American College of Rheumatology / Spondylitis Association of America / Spondyloarthritis Research and Treatment Network Izincomo zokwelashwa kwe-ankylosing spondylitis kanye ne-nonradiographic axial spondyloarthritis. Ukunakekelwa Kwe-Arthritis Res (IHoboken). 2019; 71 (10): 1285-1299. I-PMID: 31436026 pubmed.ncbi.nlm.nih.gov/31436026/.

UWerner BC, uFeuchtbaum E, uShen FH, uSamartzis D.I-Ankylosing spondylitis yomgogodla womlomo wesibeletho. Ku: Shen FH, Samartzis D, Fessler RG, ama-eds. Incwadi yombhalo wesibeletho somlomo wesibeletho. IPhiladelphia, PA: Elsevier Saunders; 2015: isahluko 28.