I-poststreptococcal glomerulonephritis (GN)

I-Poststreptococcal glomerulonephritis (GN) yisifo sezinso esenzeka ngemuva kokutheleleka ngezinhlobo ezithile zamagciwane e-streptococcus.

I-Poststreptococcal GN iyindlela ye-glomerulonephritis. Kubangelwa ukutheleleka ngohlobo lwe-streptococcus bacteria. Ukutheleleka akwenzeki ezinso, kodwa engxenyeni ehlukile yomzimba, njengesikhumba noma umphimbo. Lesi sifo singaqala amasonto amabili kuya kwamabili ngemuva kokutheleleka komphimbo okungalashwa, noma amasonto amathathu kuye kwayi-4 ngemuva kokutheleleka kwesikhumba.

Kungenzeka kubantu banoma yibuphi ubudala, kepha kuvame ukwenzeka ezinganeni ezineminyaka eyisithupha kuya kwengu-10. Noma ukutheleleka kwesikhumba nomphimbo kujwayelekile ezinganeni, i-poststreptococcal GN ayivamile ukuba inkinga yalezi zifo. I-Poststreptococcal GN ibangela ukuthi imithambo yegazi emincane esezigabeni zokuhlunga izinso (i-glomeruli) ivuvuke. Lokhu kwenza izinso zingakwazi ukuhlunga umchamo.

Lesi simo asijwayelekile namuhla ngoba ukutheleleka okungaholela ekuphazamisekeni kulashwa ngama-antibiotic.

Izici zobungozi zifaka:

• Strep umphimbo
• Ukutheleleka kwesikhumba se-Streptococcal (njenge-impetigo)

Izimpawu zingafaka noma yikuphi okulandelayo:

• Ukwehla kokukhishwa komchamo
• Umchamo onombala wokugqwala
• Ukuvuvukala (i-edema), ukuvuvukala okujwayelekile, ukuvuvukala kwesisu, ukuvuvukala kobuso noma kwamehlo, ukuvuvukala kwezinyawo, amaqakala, izandla
• Igazi elibonakalayo emchameni
• Ubuhlungu obuhlangene
• Ukuqina okuhlangene noma ukuvuvukala

Ukuhlolwa komzimba kubonisa ukuvuvukala (i-edema), ikakhulukazi ebusweni. Imisindo engajwayelekile ingazwakala lapho ulalele inhliziyo namaphaphu nge-stethoscope. Umfutho wegazi uvame ukuba phezulu.

Olunye uvivinyo olungenziwa lubandakanya:

• I-Anti-DNase B
• I-Serum ASO (ne-streptolysin O)
• Amazinga wokugcwalisa weSerum
• Ukuhlolwa komchamo
• I-biopsy yezinso (imvamisa ayidingeki)

Akukho ukwelashwa okuqondile kwalesi sifo. Ukwelashwa kugxile ekunciphiseni izimpawu.

• Ama-antibiotic, njenge-penicillin, kungenzeka asetshenziselwe ukubhubhisa noma yimaphi amabhaktheriya e-streptococcal asele emzimbeni.
• Imithi yengcindezi yegazi nemithi yokwesula kungadingeka ukulawula ukuvuvukala nomfutho wegazi ophezulu.
• I-Corticosteroids neminye imithi elwa nokuvuvukala ngokuvamile ayisebenzi.

Ungadinga ukukhawulela usawoti ekudleni kwakho ukuze ulawule ukuvuvukala nomfutho wegazi ophezulu.

I-Poststreptococcal GN ivame ukuzihambela yodwa emva kwamasonto ambalwa kuye ezinyangeni.

Kwisibalo esincane sabantu abadala, kungahle kube kubi kakhulu futhi kuholele ekuhlulekeni kwezinso zesikhathi eside (ezingapheli). Kwesinye isikhathi, ingaqhubekela phambili ize ifike esigabeni sesifo sezinso, esidinga i-dialysis kanye nokufakelwa kwezinso.

Izinkinga zempilo ezingabangelwa yilesi sifo zifaka:

• Ukwehluleka okukhulu kwezinso (ukulahleka okusheshayo kwezinso 'ikhono lokususa imfucuza nokusiza ukulinganisela uketshezi nama-electrolyte emzimbeni)
• I-glomerulonephritis engapheli
• Isifo sezinso esingalapheki
• Ukwehluleka kwenhliziyo noma i-edema yamaphaphu (i-fluid buildup emaphashini)
• Isifo sezinso sokugcina
• I-Hyperkalemia (izinga eliphakeme kakhulu le-potassium egazini)
• Umfutho wegazi ophezulu (umfutho wegazi ophakeme)
• I-Nephrotic syndrome (iqembu lezimpawu ezibandakanya amaprotheni emchameni, amazinga aphansi wamaprotheni egazini, amazinga aphezulu e-cholesterol, amazinga aphezulu e-triglyceride nokuvuvukala)

Shayela umhlinzeki wakho wezempilo uma:

• Unezimpawu ze-poststreptococcal GN
• Une-poststreptococcal GN, futhi wehlise ukuphuma komchamo noma ezinye izimpawu ezintsha

Ukwelapha ukutheleleka okwaziwayo kwe-streptococcal kungasiza ekuvimbeleni i-poststreptococcal GN. Futhi, ukwenza inhlanzeko enhle njengokugeza izandla kuvimbela ukusabalala kwesifo.

I-Glomerulonephritis - i-poststreptococcal; I-glomerulonephritis engatheleleki

• Ukwakheka kwezinso
• I-Glomerulus nephron

I-Flores FX. Izifo ezihlukanisiwe ezihlotshaniswa ne-hematuria eyedlulele ephindaphindwayo. Ku: Kliegman RM, St Geme JW, Blum NJ, Shah SS, Tasker RC, Wilson KM, eds. Incwadi kaNelson Yezingane. Umhlaka 21. IPhiladelphia, PA: Elsevier; 2020: isahluko 537.

USaha MK, iPendergraft WF, uJennette JC, uFalk RJ. Isifo esiyisisekelo se-glomerular. Ku: Yu ASL, Chertow GM, Luyckx VA, Marsden PA, Skorecki K, Taal MW, ama-eds. IBrenner neRector's The Kidney. Umhla ka-11. IPhiladelphia, PA: Elsevier; 2020: isahluko 31.