I-thrombocytopenia eyenziwe yizidakamizwa

I-Thrombocytopenia yinoma yikuphi ukuphazamiseka lapho kungekho khona amaplatelet anele. Ama-platelets amangqamuzana asegazini asiza i-clot yegazi. Ukubalwa kweplatelet okuphansi kwenza ukuphuma kwegazi kube lula kakhulu.

Lapho imithi noma izidakamizwa kuyizimbangela zenani eliphansi leplatelet, ibizwa ngokuthi i-thrombocytopenia eyenziwe yizidakamizwa.

I-thrombocytopenia eyenziwe yizidakamizwa yenzeka lapho imithi ethile icekela ama-platelet noma iphazamisa amandla omzimba okwenza okwanele ngayo.

Kunezinhlobo ezimbili ze-thrombocytopenia eyenziwe yizidakamizwa: i-immune ne-nonimmune.

Uma umuthi ubangela ukuthi umzimba wakho ukhiqize amasosha omzimba, afuna futhi aqede ama-platelet akho, lesi simo sibizwa ngokuthi yi-immune thrombocytopenia eyenziwe yizidakamizwa. I-Heparin, egazini elincanyana, iyimbangela evame kakhulu ye-immune thrombocytopenia eyenziwe yizidakamizwa.

Uma umuthi uvimbela umnkantsha wakho ekwenzeni amaplatelet anele, lesi simo sibizwa ngokuthi i-nonimmune thrombocytopenia eyenziwe yizidakamizwa. Izidakamizwa zeChemotherapy kanye nomuthi wokuquleka obizwa nge-valproic acid kungaholela kule nkinga.

Eminye imithi edala i-thrombocytopenia eyenziwe yizidakamizwa ihlanganisa:

• UFurosemide
• Igolide, lisetshenziselwa ukwelapha i-arthritis
• Izidakamizwa ezingezona ukuvuvukala (ama-NSAID)
• I-penicillin
• I-Quinidine
• I-Quinine
• I-Ranitidine
• AmaSulfonamides
• I-Linezolid namanye ama-antibiotic
• Izitatimende

Ukwehla kwama-platelet kungadala:

• Ukopha okungavamile
• Ukopha lapho uxubha amazinyo
• Ukulinyazwa okulula
• Khomba izindawo ezibomvu esikhunjeni (petechiae)

Isinyathelo sokuqala ukuyeka ukusebenzisa umuthi odala inkinga.

Kubantu abanegazi elisongela ukuphila, ukwelashwa kungafaka:

• Ukwelashwa kwe-Immunoglobulin (IVIG) okunikezwa ngomthambo
• Ukushintshaniswa kwe-Plasma (plasmapheresis)
• Ukumpontshelwa kweplatelet
• Umuthi weCorticosteroid

Ukopha kungasongela impilo uma kwenzeka ebuchosheni noma kwezinye izitho.

Owesifazane okhulelwe onamasosha omzimba kuma-platelet angadlulisela amasosha omzimba enganeni esesibelethweni.

Shayela umhlinzeki wakho wezokunakekelwa kwezempilo uma unegazi elichazayo noma ukulimaza futhi uthatha imithi, njengaleyo eshiwo ngenhla ngaphansi kwezimbangela.

I-thrombocytopenia eyenziwe yizidakamizwa; I-immune thrombocytopenia - isidakamizwa

• Ukwakheka kwegazi
• Amahlule egazi

Abrams CS. I-Thrombocytopenia. Ku: IGoldman L, iSchafer AI, ama-eds. Imithi yeGoldman-Cecil. Umhla ka-25. IPhiladelphia, PA: Elsevier Saunders; 2016: isahluko 172.

I-Warkentin TE. I-Thrombocytopenia ebangelwa ukubhujiswa kweplatelet, hypersplenism, noma i-hemodilution. Ku: Hoffman R, Benz EJ, Silberstein LE, et al, ama-eds. I-Hematology: Izimiso Eziyisisekelo Nokuzijwayeza. Umhla wesi-7. IPhiladelphia, PA: Elsevier; 2018: isahluko 132.