Inaliti ye-Tacrolimus

-Delile

• Ngaphambi kokuthola umjovo we-tacrolimus,
• Umjovo we-tacrolimus ungadala imiphumela emibi. Tshela udokotela wakho uma kukhona kulezi zimpawu ezinzima noma ezingapheli:
• Eminye imiphumela emibi ingaba mibi. Uma uhlangabezana nalezi zimpawu ezilandelayo, noma lezo ezishiwo esigabeni ESIBALULEKILE SESEXWAYISO, shayela udokotela wakho ngokushesha:
• Izimpawu zokudlula ngokweqile zingafaka:

Umjovo we-tacrolimus kufanele unikezwe kuphela ngaphansi kokuqondisa kukadokotela onolwazi lokwelapha abantu abafakelwe izitho zomzimba kanye nokunikeza imithi eyehlisa ukusebenza kwamasosha omzimba.

Umjovo we-tacrolimus unciphisa ukusebenza kwesistimu yakho yomzimba. Lokhu kungakhuphula ubungozi bokuthi uthole ukutheleleka okunzima. Uma uhlangabezana nalezi zimpawu ezilandelayo, shayela udokotela wakho ngokushesha: umphimbo obuhlungu; ukukhwehlela; imfiva; ukukhathala ngokweqile; izimpawu ezinjengomkhuhlane; isikhumba esifudumele, esibomvu, noma esibuhlungu; noma ezinye izimpawu zokutheleleka.

Lapho amasosha akho omzimba engasebenzi ngendlela ejwayelekile, kungaba nengozi enkulu yokuthi uzoba nomdlavuza, ikakhulukazi i-lymphoma (uhlobo lomdlavuza oluqala kumaseli amasosha omzimba). Uma uthola umjovo we-tacrolimus isikhathi eside noma eminye imishanguzo eyehlisa ukusebenza kwamasosha omzimba, futhi amazinga akho ale mithi ayanda, le ngozi inganda kakhulu. Uma uhlangabezana nanoma yiziphi kulezi zimpawu ezilandelayo ze-lymphoma, shayela udokotela wakho ngokushesha: ama-lymph node avuvukile entanyeni, emakhwapheni, noma emgodini; ukuncipha komzimba; imfiva; ukujuluka ebusuku; ukukhathala ngokweqile noma ubuthakathaka; ukukhwehlela; ukuphefumula kanzima; ubuhlungu besifuba; noma ubuhlungu, ukuvuvukala, noma ukugcwala endaweni yesisu.

Khuluma nodokotela wakho ngezingozi zokuthola umjovo we-tacrolimus.

Umjovo we-tacrolimus usetshenziswa kanye neminye imithi ukuvimbela ukwenqatshwa (ukuhlaselwa kwesitho esifakelwe kabusha amasosha omzimba womamukeli wokufakelwa) kubantu abathole ukufakelwa izinso, isibindi, noma inhliziyo. Umjovo we-tacrolimus kufanele usetshenziswe kuphela ngabantu abangakwazi ukuthatha i-tacrolimus ngomlomo. Umjovo we-tacrolimus usesigabeni semithi ebizwa ngama-immunosupressants. Isebenza ngokunciphisa ukusebenza kwamasosha omzimba ukuyivimba ekuhlaseleni isitho esitshalwe kabusha.

Umjovo weTacrolimus uza njengesisombululo (uketshezi) sokujova ngomjovo (emthanjeni) ngudokotela noma umhlengikazi esibhedlela noma esikhungweni sezokwelapha. Imvamisa inikezwa njengokumnika okuqhubekayo, kuqala kungakapheli amahora angama-6 ngemuva kokuhlinzwa kokufakelwa futhi kuqhubeke kuze kube yilapho i-tacrolimus ingathathwa ngomlomo.

Udokotela noma umhlengikazi uzokubuka eduze phakathi nemizuzu yokuqala engama-30 yokwelashwa kwakho bese ezokuqapha kaningi ukuze welashwe ngokushesha uma unegciwane elibi.

Lo muthi ungabekelwa okunye ukusetshenziswa; buza udokotela wakho noma usokhemisi ukuthola eminye imininingwane.

Ngaphambi kokuthola umjovo we-tacrolimus,

• Tshela udokotela wakho kanye nosokhemisi uma unegciwane ku-tacrolimus, noma imiphi eminye imithi, i-polyoxyl 60 hydrogenated castor oil (HCO-60) noma eminye imithi equkethe uwoyela we-castor. Buza udokotela noma usokhemisi wakho uma ungazi ukuthi umuthi owugulayo unawo yini uwoyela we-castor.
• Tshela udokotela wakho kanye nosokhemisi ukuthi imiphi imishanguzo kadokotela noma engabhaliswanga, amavithamini, kanye nezithako zokudla okunomsoco ozithathayo noma ohlela ukuzithatha. Qiniseka ukuthi usho noma yikuphi okulandelayo: i-amphotericin B (i-Abelcet, i-Ambisome, i-Amphotec); ama-antacids; ama-antibiotic athile afaka i-aminoglycosides efana ne-amikacin, i-gentamicin, i-neomycin (i-Neo-Fradin), i-streptomycin, ne-tobramycin (i-Tobi), nama-macrolides afana ne-clarithromycin (Biaxin), i-erythromycin (i-EES, i-E-Mycin, i-Erythrocin), ne-troleandomycin (TAO) (ayitholakali e-US); imishanguzo ye-antifungal efana ne-clotrimazole (Lotrimin, Mycelex), i-fluconazole (i-Diflucan), i-itraconazole (i-Sporanox), i-ketoconazole (i-Nizoral) ne-voriconazole (i-Vfend); i-bromocriptine (Parlodel); ama-calcium channel blocker afana ne-diltiazem (Cardizem), nicardipine (Cardene), nifedipine (Adalat, Procardia), kanye ne-verapamil (Calan, Covera, Isoptin); i-caspofungin (Cancidas); i-chloramphenicol; i-cimetidine (Tagamet); i-cisapride (Propulsid) (ayitholakali e-U.S.); i-cisplatin (iPlatinol); i-danazol (iDanocrine); isisu esithile (’amaphilisi amanzi’); i-ganciclovir (i-cytovene); izindlela zokuvimbela inzalo zamahomoni (amaphilisi okulawula ukubeletha, amabala, izindandatho, ukufaka, noma imijovo); I-HIV protease inhibitors efana ne-indinavir (Crixivan), nelfinavir (Viracept), ne-ritonavir (Norvir); i-lansoprazole (Prevacid); imithi ethile yokuquleka efana ne-carbamazepine (Tegretol), phenobarbital, ne-phenytoin (Dilantin); i-methylprednisolone (iMedrol); i-metoclopramide (Reglan); nefazodone; omeprazole (Prilosec); i-rifabutin (i-Mycobutin); i-rifampin (i-Rifadin, i-Rimactane); futhi sirolimus (Rapamune). Udokotela wakho angadinga ukushintsha imithamo yemithi yakho noma akuqaphele ngokucophelela ngemiphumela emibi. Eminye imithi eminingi ingaxhumana ne-tacrolimus, ngakho-ke tshela udokotela wakho ngayo yonke imithi oyiphuzayo, ngisho nalawo angaveli kulolu hlu.
• Tshela udokotela wakho uma uthola noma usanda kuyeka ukuthola i-cyclosporine (Gengraf, Neoral, Sandimmune). Ukube ubuthola i-cyclosporine, udokotela wakho cishe ngeke aqale ukukunika umjovo we-tacrolimus kuze kube amahora angama-24 ngemuva kokuthola umthamo wakho wokugcina we-cyclosporine. Uma uyeka ukuthola umjovo we-tacrolimus, udokotela wakho uzokutshela nokuthi ulinde amahora angama-24 ngaphambi kokuqala ukuthatha i-cyclosporine.
• utshele udokotela wakho kanye nosokhemisi ukuthi yimiphi imikhiqizo yamakhambi oyithathayo, ikakhulukazi iSort John's wort.
• utshele udokotela wakho uma uke waba nesifo senhliziyo, sezinso, noma sesibindi.
• tshela udokotela wakho uma ukhulelwe, hlela ukukhulelwa, noma uncelisa. Uma ukhulelwa ngenkathi uthola umjovo we-tacrolimus, shayela udokotela wakho.
• uma uhlinzwa, kufaka phakathi ukuhlinzwa kwamazinyo, tshela udokotela noma udokotela wamazinyo ukuthi uthola umjovo we-tacrolimus.
• kufanele wazi ukuthi ukuthola umjovo we-tacrolimus kungakhuphula ubungozi bokuba nomdlavuza wesikhumba. Zivikele emdlavuzeni wesikhumba ngokugwema ukuvezwa yilanga noma i-ultraviolet light (imibhede yokushuka) nokugqoka izimpahla zokuzivikela, izibuko zelanga, kanye nesivikelo selanga esinokuvikelwa kwesikhumba (SPF).
• kufanele wazi ukuthi umjovo we-tacrolimus ungadala umfutho wegazi ophezulu. Udokotela wakho uzoqapha ukucindezelwa kwegazi lakho ngokucophelela, futhi angakunikeza nemithi yokwelapha umfutho wegazi ophakeme uma ikhula.
• kufanele wazi ukuthi kunengozi yokuthi uzoba nesifo sikashukela ngesikhathi sokwelashwa kwakho ngomjovo we-tacrolimus. Iziguli zase-Afrika zaseMelika nezaseSpain ezifakelwe ukufakelwa izinso zisengozini enkulu kakhulu yokuba nesifo sikashukela ngesikhathi sezelashwa ngomjovo we-tacrolimus. Tshela udokotela wakho uma wena noma omunye emndenini wakho unesifo sikashukela noma wake waba naso. Uma uhlangabezana nalezi zimpawu ezilandelayo, shayela udokotela wakho ngokushesha: ukoma ngokweqile; ukulamba ngokweqile; ukuchama njalo; ukungaboni kahle noma ukudideka.
• ungenayo imigomo ngaphandle kokukhuluma nodokotela wakho.

Gwema ukudla isithelo samagilebhisi noma ukuphuza ijusi lamagilebhisi ngenkathi uthola umjovo we-tacrolimus.

Umjovo we-tacrolimus ungadala imiphumela emibi. Tshela udokotela wakho uma kukhona kulezi zimpawu ezinzima noma ezingapheli:

• ikhanda
• ukuzamazama okungalawuleki kwengxenye yomzimba
• isifo sohudo
• ukuqunjelwa
• isicanucanu
• ukuhlanza
• isilungulela
• ubuhlungu besisu
• ukulahlekelwa isifiso sokudla
• ubunzima bokulala noma ukulala
• isiyezi
• ubuthakathaka
• ubuhlungu emuva noma ngokuhlanganyela
• ukushisa, ukuba ndikindiki, ubuhlungu noma ukuhayiza ezandleni noma ezinyaweni

Eminye imiphumela emibi ingaba mibi. Uma uhlangabezana nalezi zimpawu ezilandelayo, noma lezo ezishiwo esigabeni ESIBALULEKILE SESEXWAYISO, shayela udokotela wakho ngokushesha:

• isifuba
• ukuqubuka
• ukulunywa
• ukuphefumula kanzima noma ukugwinya
• ukuncipha kokuchama
• ubuhlungu noma ukushisa ekuchameni
• ukuvuvukala kwezingalo, izandla, izinyawo, amaqakala noma imilenze engezansi
• ukuzuza kwesisindo
• ukopha okungajwayelekile noma ukulinyazwa
• isithuthwane
• ikhoma (ukulahlekelwa ukwazi isikhathi esithile)

Umjovo we-tacrolimus ungadala eminye imiphumela emibi. Shayela udokotela wakho uma unezinkinga ezingavamile ngenkathi uthola lo muthi.

Uma uthola imiphumela emibi kakhulu, wena noma udokotela wakho ungathumela umbiko kuhlelo lwe-Food and Drug Administration's (FDA) MedWatch Adverse Event Reporting online (http://www.fda.gov/Safety/MedWatch) noma ngocingo ( 1-800-332-1088).

Uma kwenzeka ukweqisa ngokweqile, shayela ucingo losizo lokulawula ubuthi ku-1-800-222-1222. Imininingwane iyatholakala online ku-https: //www.poisonhelp.org/help. Uma isisulu siwile, saba nokuquleka, sinenkinga yokuphefumula, noma singakwazi ukuvuswa, shayela ngokushesha abezimo eziphuthumayo ku-911.

Izimpawu zokudlula ngokweqile zingafaka:

• isifuba
• ubuthongo

Gcina wonke ama-aphoyintimenti nodokotela wakho kanye nelabhorethri. Udokotela wakho uzo-oda izivivinyo ezithile ukuze ahlole impendulo yomzimba wakho kumjovo we-tacrolimus.

Kubalulekile ukuthi ugcine uhlu olubhaliwe lwayo yonke imishanguzo oyisebenzisayo kadokotela kanye nokungabhaliswanga (ngaphezulu kokuthenga), kanye nanoma yimiphi imikhiqizo efana namavithamini, amaminerali, noma ezinye izithako zokudla. Kufanele uze nalolu hlu njalo uma uvakashela udokotela noma uma ungeniswa esibhedlela. Kubaluleke kakhulu futhi nemininingwane ebalulekile ukuthi uphathe uma kwenzeka kunezimo eziphuthumayo.

• Prograf^®

• FK 506