Ama-Fibrates

Ama-fibrate yimithi enqunyelwe ukusiza ukwehlisa amazinga aphezulu e-triglyceride. AmaTriglycerides awuhlobo lwamafutha egazini lakho. Ama-fibrate nawo angasiza ekukhuphuleni i-cholesterol yakho ye-HDL (enhle).

Ama-triglycerides aphezulu kanye ne-cholesterol ephansi ye-HDL kwandisa ubungozi besifo senhliziyo nesifo sohlangothi.

Ukwehlisa i-cholesterol ne-triglycerides kungakusiza ekuvikeleni ezifweni zenhliziyo, ekuhlaselweni yinhliziyo nasekushayweni unhlangothi.

Izitatimende kucatshangwa ukuthi yimithi engcono kakhulu ongayisebenzisa kubantu abadinga imithi yokwehlisa i-cholesterol yabo.

Amanye ama-fibrate angabekwa kanye nama-statins ukusiza ukwehlisa i-cholesterol. Kodwa-ke, ezinye izifundo zibonisa ukuthi ukusebenzisa ama-fibrate athile kanye nama-statins kungahle kungasizi ekwehliseni ubungozi bokuhlaselwa yisifo senhliziyo noma ukushaywa unhlangothi kunokusebenzisa ama-statins kuphela.

Ama-fibrate nawo angasetshenziswa ukusiza ukwehlisa ama-triglycerides aphakeme kakhulu kubantu abasengozini ye-pancreatitis.

Ama-fibrate anqunyelwe abantu abadala.

Thatha umuthi wakho njengokuyalelwa.Ngokuvamile kuthathwa 1 isikhathi ngosuku. Ungayeki ukuthatha umuthi wakho ngaphandle kokuqala ukhulume nomhlinzeki wakho wezokunakekelwa kwempilo.

Umuthi uza ngefomu eligcwele uketshezi noma ifomu lethebulethi. Ungavuli amaphilisi, uhlafune, noma uxove amaphilisi ngaphambi kokuthatha.

Funda imiyalo elebula lakho lomuthi. Eminye imikhiqizo kufanele ithathwe ngokudla. Abanye bangathathwa nokudla, noma ngaphandle kokudla.

Gcina yonke imithi yakho endaweni epholile, eyomile.

Landela ukudla okunempilo ngenkathi uthatha ama-fibrate. Lokhu kufaka phakathi ukudla amafutha amancane ekudleni kwakho. Ezinye izindlela ongasiza ngazo inhliziyo yakho zifaka:

• Ukuvivinya umzimba njalo
• Ukulawula ukucindezeleka
• Ukuyeka ukubhema

Ngaphambi kokuba uqale ukuthatha ama-fibre, tshela umhlinzeki wakho uma:

• Ukhulelwe, hlela ukukhulelwa, noma ukuncelisa. Omama abahlengikazi akufanele bathathe lo muthi.
• Unomzimba ongezwani nawo
• Bathatha eminye imithi
• Hlela ukuhlinzwa noma umsebenzi wamazinyo
• Unesifo sikashukela

Uma unesimo sesibindi, i-gallbladder, noma izinso, akufanele uthathe ama-fibrate.

Tshela umhlinzeki wakho ngayo yonke imithi yakho, izithasiselo, amavithamini, namakhambi. Imithi ethile ingahlangana nama-fibrate. Qiniseka ukuthi utshela umhlinzeki wakho ngaphambi kokuthatha noma yimiphi imithi emisha.

Ukuhlolwa kwegazi njalo kuzokusiza wena nomhlinzeki wakho:

• Bona ukuthi umuthi usebenza kahle kanjani
• Ukuqapha imiphumela emibi, njengezinkinga zesibindi

Imiphumela emibi engaba khona ingafaka:

• Ubuhlungu bekhanda
• Ukuqunjelwa
• Uhudo
• Isiyezi
• Ubuhlungu besisu

Shayela umhlinzeki wakho uma uqaphela:

• Ubuhlungu besisu
• Ubuhlungu bemisipha noma ubumnene
• Ubuthakathaka
• Ukuphuzi kwesikhumba (i-jaundice)
• Ukuqhuma kwesikhumba
• Ezinye izimpawu ezintsha

Ummeli we-Antilipemic; I-Fenofibrate (i-Antara, i-Fenoglide, i-Lipofen, i-Tricor, ne-Triglide); I-Gemfibrozil (iLopid); I-Fenofibric acid (iTrilipix); Hyperlipidemia - imicu emide; Ukuqina kwemithambo - ama-fibrate; Cholesterol - imicu; Hypercholesterolemia - imicu emincane; I-dyslipidemia - imicu emide

Iwebhusayithi yeAmerican Heart Association. Imithi ye-cholesterol. www.heart.org/en/health-topics/cholesterol/prevention-and-treatment-of-high-cholesterol-hyperlipidemia/cholesterol-medications. Kubuyekezwe ngoNovemba 10, 2018. Kufinyelelwe ngoMashi 4, 2020.

UGenest J, ukuphazamiseka kweLibby P. Lipoprotein nesifo senhliziyo. Ku: Zipes DP, Libby P, Bonow RO, Mann DL, Tomaselli GF, Braunwald E, ama-eds. Isifo Senhliziyo SikaBraunwald: Incwadi Yemithi Yezinhliziyo Nemithambo. Umhla ka-11. IPhiladelphia, PA: Elsevier; 2019: isahluko 48.

I-Grundy SM, i-Stone NJ, i-Bailey AL, et al. 2018 AHA / ACC / AACVPR / AAPA / ABC / ACPM / ADA / AGS / APhA / ASPC / NLA / PCNA umhlahlandlela wokuphathwa kwe-cholesterol yegazi: umbiko we-American College of Cardiology / American Heart Association Task Force on Guidelines Practice Guidelines . UJ Am Coll Cardiol. 2019; 73 (24): e285 – e350. I-PMID: 30423393 pubmed.ncbi.nlm.nih.gov/30423393/.

UJones PH, Brinto EA. Ama-Fibrates. Ku: Ballantyne CM, ed. I-Clinical Lipidology: Umngane Wesifo Senhliziyo SaseBraunwald. Okwesibili. IPhiladelphia, PA: Elsevier Saunders; 2015: isahluko 25.

Iwebhusayithi ye-US Food and Drug Administration. Ukuxhumana nokuphepha kwezidakamizwa kwe-FDA: buyekeza isibuyekezo se-trilipix (fenofibric acid) kanye necala le-ACCORD lipid. www.fda.gov/drugs/drug-safety-and-availability/fda-drug-safety-communicationreview-update-trilipix-fenofibric-acid-and-accord-lipid-trial. Kubuyekezwe uFebhuwari 13, 2018. Kufinyelelwe kuMashi 4, 2020.

• Imithi Ye-cholesterol
• Ama-Triglycerides