I-hypersensitivity vasculitis

I-Hypersensitivity vasculitis ukusabela okweqile kumuthi, ukutheleleka, noma into yangaphandle. Kuholela ekuvukeleni nasekulimaleni kwemithambo yegazi, ikakhulukazi esikhumbeni. Leli gama alisasetshenziswa kakhulu njengamanje ngoba amagama athile acatshangwa njenganembe kakhulu.

I-Hypersensitivity vasculitis, noma i-vasculitis yesitsha esincane esinqunyiwe, ibangelwa:

• Ukungezwani komzimba nomuthi noma enye into yangaphandle
• Ukusabela kokutheleleka

Imvamisa kuthinta abantu abadala kuneminyaka eyi-16.

Imvamisa, imbangela yenkinga ayitholakali ngisho nokucwaninga ngomlando wezokwelapha.

I-Hypersensitivity vasculitis ingabukeka njenge-systemic, necrotizing vasculitis, engathinta imithambo yegazi emzimbeni wonke hhayi esikhunjeni kuphela. Ezinganeni, kungabonakala njenge-Henoch-Schonlein purpura.

Izimpawu zingafaka:

• Ukuqhuma okusha okunezindawo ezinethenda, nsomi noma nsundu ngokubomvu ezindaweni ezinkulu
• Izilonda zesikhumba zitholakala kakhulu emilenzeni, ezinqeni, noma esiqwini
• Amabhamuza esikhunjeni
• I-Hives (urticaria), ingahlala isikhathi eside kunamahora angama-24
• Izilonda ezivulekile ezinezicubu ezifile (izilonda ze-necrotic)

Umhlinzeki wezokunakekelwa kwempilo uzosekela ukuxilongwa ezimpawu. Umhlinzeki uzobuyekeza noma imiphi imithi noma imishanguzo oyithathile kanye nezifo ezisanda kutholakala. Uzobuzwa ngokukhwehlela, umkhuhlane, noma ubuhlungu besifuba.

Ukuhlolwa okuphelele komzimba kuzokwenziwa.

Ukuhlolwa kwegazi nomchamo kungenziwa ukubheka ukuphazamiseka kwesistimu okunje nge-systemic lupus erythematosus, dermatomyositis, noma i-hepatitis C. Ukuhlolwa kwegazi kungafaka:

• Gcwalisa inani legazi ngokuhluka
• Isilinganiso se-erythrocyte sedimentation
• Iphaneli leKhemistry eline-enzyme yesibindi ne-creatinine
• I-antiinuclear antibody (ANA)
• Isici se-rheumatoid
• Amasosha omzimba antineutrophil cytoplasmic (ANCA)
• Qedela amazinga
• Ama-Cryoglobulins
• Ukuhlolwa kwe-Hepatitis B no-C
• Ukuhlolelwa i-HIV
• Ukuhlolwa komchamo

I-biopsy yesikhumba ikhombisa ukuvuvukala kwemithambo yegazi emincane.

Umgomo wokwelashwa ukunciphisa ukuvuvukala.

Umhlinzeki wakho anganikeza i-aspirin, izidakamizwa ezingezona ukuvuvukala (ama-NSAID), noma ama-corticosteroids ukunciphisa ukuvuvukala kwemithambo yegazi. (UNGANIKI i-aspirin ezinganeni ngaphandle kwalapho welulekwa ngumhlinzeki wakho)

Umhlinzeki wakho uzokutshela ukuthi uyeke ukuthatha imishanguzo engadala lesi simo.

I-Hypersensitivity vasculitis ivame ukuhamba ngokuhamba kwesikhathi. Isimo singabuyela kwabanye abantu.

Abantu abane-vasculitis eqhubekayo kufanele bahlolwe i-systemic vasculitis.

Izinkinga zingafaka:

• Ukulimala okungapheli emithanjeni yegazi noma esikhunjeni ngesibazi
• Imithambo yegazi evuthayo ethinta izitho zangaphakathi

Shayela umhlinzeki wakho uma unezimpawu ze-hypersensitivity vasculitis.

UNGAYITHATHI imishanguzo edale ukungezwani nesikhathi esedlule.

I-vasculitis yesitsha esincane esinqunyiwe; I-vasculitis yokungezwani komzimba; I-leukocytoclastic vasculitis

• I-Vasculitis entendeni
• I-Vasculitis
• I-Vasculitis - urticarial esandleni

IHabif TP. Hypersensitivity syndromes kanye ne-vasculitis. Ku: Habif TP, ed. Ukwelashwa Kwemithi Yezokwelapha. Umhlaka 6. IPhiladelphia, PA: Elsevier; 2016: isahluko 18.

UJennette JC, Falk RJ, Bacon PA, et al. U-2012 obuyekezwe ukuqokwa kwengqungquthela yesivumelwano se-International Chapel Hill yama-vasculitides. I-Arthritis Rheum. 2013; 65 (1): 1-11. I-PMID: 23045170 www.ncbi.nlm.nih.gov/pubmed/23045170.

IPatterson JW. Iphethini yokuphendula ye-vasculopathic. Ku: Patterson JW, ed. I-Weedon's Skin Pathology. Umhla wesi-4. IPhiladelphia, PA: Elsevier Churchill Livingstone; 2016: isahluko 8.

Itshe uJH. Ama-vasculitides ahlelekile. Ku: IGoldman L, iSchafer AI, ama-eds. Imithi yeGoldman-Cecil. Umhla ka-25. IPhiladelphia, PA: Elsevier Saunders; 2016: isahluko 270.

ISunderkötter CH, uZelger B, Chen KR, et al. Ukuqanjwa kwamagama kwe-vasculitis enqunyiwe: i-dermatologic addendum engqungqutheleni ye-Revised International Chapel Hill Consensus Conference ka-2012 ye-Vasculitides. I-Arthritis Rheumatol. I-2018; 70 (2): 171-184. I-PMID: 29136340 www.ncbi.nlm.nih.gov/pubmed/29136340.