Ukuhlolwa kwe-Methylene blue

Ukuhlolwa kwe-methylene blue kusivivinyo sokuthola uhlobo noma ukwelapha i-methemoglobinemia, isifo segazi.

Umhlinzeki wezempilo usonga ibhande eliqinile noma umfutho wegazi ozungeze ingalo yakho ephezulu. Ingcindezi ibangela ukuthi imithambo engezansi kwendawo igcwale igazi.

Ingalo ihlanzwa ngombulali wegciwane (isinqandakuvunda). Kufakwa inaliti emthanjeni wakho, imvamisa eseduze nengaphakathi lendololwane noma emuva kwesandla. Ishubhu elincanyana, elibizwa ngokuthi i-catheter, lifakwa emthanjeni. (Lokhu kungabizwa nge-IV, okusho ukuthi kufakwa imithambo yegazi). Ngenkathi ishubhu lihlala endaweni, inaliti ne-tourniquet kuyasuswa.

Impuphu eluhlaza emnyama ebizwa nge-methylene blue ingena ngeshubhu iye emthanjeni wakho. Umhlinzeki ubheka ukuthi impuphu iguqula kanjani into esegazini ebizwa nge-methemoglobin ibe yi-hemoglobin ejwayelekile.

Akukho ukulungiselela okukhethekile okudingekayo kulolu vivinyo.

Lapho inaliti ifakwa ukudonsa igazi, abanye abantu bezwa ubuhlungu obulinganiselayo. Abanye bazizwa beshaywa noma betinyelwa kuphela. Ngemuva kwalokho, kungahle kube nokushaywa okuthile noma ukulinyazeka okuncane. Lokhu maduzane kuyaphela.

Kunezinhlobo eziningana zamaprotheni athwala umoya-mpilo egazini. Omunye wabo yi-methemoglobin. Izinga elijwayelekile le-methemoglobin egazini imvamisa liyi-1%. Uma izinga liphakeme, ungagula ngoba iphrotheni alithwali umoya-mpilo. Lokhu kungenza igazi lakho libukeke linsundu esikhundleni sokubomvu.

I-Methemoglobinemia inezimbangela eziningana, eziningi zazo ezofuzo (inkinga ngezakhi zakho zofuzo). Lokhu kuhlolwa kusetshenziselwa ukutshela umehluko phakathi kwe-methemoglobinemia okubangelwa ukungabi khona kweprotheni ebizwa nge-cytochrome b5 reductase nezinye izinhlobo ezidluliselwa ngemindeni (ezuzwe njengefa). Udokotela wakho uzosebenzisa imiphumela yalolu vivinyo ukusiza ukunquma ukwelashwa kwakho.

Ngokuvamile, i-methylene eluhlaza okwesibhakabhaka yehlisa ngokushesha izinga le-methemoglobin egazini.

Ububanzi bamanani ajwayelekile bungahluka kancane phakathi kwamalabhorethri ahlukene. Amanye amalebhu asebenzisa izilinganiso ezahlukahlukene noma avivinye amasampula ahlukile. Khuluma nomhlinzeki wakho mayelana nencazelo yemiphumela yakho ethile yokuhlolwa.

Ungaba nohlobo olungavamile lwe-methemoglobinemia uma lokhu kuhlolwa kungalinciphisi kakhulu izinga legazi le-methemoglobin.

Kunengozi encane ethintekayo ekuthatheni igazi lakho. Imithambo nemithambo yegazi kuyahluka ngosayizi komunye umuntu kuya kolunye uhlangothi lomzimba kuya kolunye. Ukufaka i-IV kungaba nzima kakhulu kuwe noma enganeni yakho kunakwabanye abantu.

Ezinye izingozi ezihambisana nalolu hlobo lokuhlolwa kwegazi zincane, kepha zingafaka:

• Ukopha ngokweqile
• Ukuquleka noma uzizwe unekhanda elincane
• Ukubhoboza okuningi ukuthola imithambo
• I-Hematoma (igazi elinqwabelana ngaphansi kwesikhumba lidala ukulinyazwa)
• Ukutheleleka (ingozi encane noma kunini lapho isikhumba siphukile, kepha amathuba okutheleleka anda isikhathi eside lapho i-IV ihlala emthanjeni)

I-Methemoglobinemia - ukuhlolwa kwe-methylene blue

I-Benz EJ, i-Ebert BL. Ukwahluka kwe-hemoglobin okuhambisana ne-hemolytic anemia, ukushintsha kwe-oxygen, kanye ne-methemoglobinemias. Ku: Hoffman R, Benz EJ, Silberstein LE, et al, ama-eds. I-Hematology: Izimiso Eziyisisekelo Nokuzijwayeza. Umhla wesi-7. IPhiladelphia, PA: Elsevier; 2018: isahluko 43.

IChernecky CC, iBerger BJ. I-Methemoglobin - igazi. Ku: IChernecky CC, iBerger BJ, ama-eds. Ukuhlolwa Kwelabhoratri Nezinqubo Zokuxilonga. Umhlaka 6. ISt Louis, MO: Elsevier Saunders; 2013: 781-782.