Ukuhlolwa kwe-ALP isoenzyme

I-alkaline phosphatase (ALP) iyi-enzyme etholakala ezicutshini eziningi zomzimba ezinjengesibindi, imisele yamathambo, ithambo namathumbu. Kunezinhlobo ezahlukahlukene ze-ALP ezibizwa nge-isoenzymes. Isakhiwo se-enzyme sincike ekutheni ikhiqizwa kuphi emzimbeni. Lokhu kuhlolwa kuvame ukusetshenziselwa ukuhlola i-ALP eyenziwe ezicutshini zesibindi namathambo.

Ukuhlolwa kwe-ALP isoenzyme ukuhlolwa kwelebhu okulinganisa amanani ezinhlobo ezahlukene ze-ALP egazini.

Ukuhlolwa kwe-ALP ukuhlolwa okuhlobene.

Kudingeka isampula yegazi. Isikhathi esiningi igazi likhishwa emthanjeni ongaphakathi endololwaneni noma ngemuva kwesandla.

Akufanele udle noma uphuze noma yini amahora ayi-10 kuya kwayi-12 ngaphambi kokuhlolwa, ngaphandle kwalapho umhlinzeki wakho wezempilo ekutshela ukuthi wenze kanjalo.

Imithi eminingi ingaphazamisa imiphumela yokuhlolwa kwegazi.

• Umhlinzeki wakho uzokutshela uma udinga ukuyeka ukuthatha noma yimiphi imithi ngaphambi kokwenza lokhu kuhlolwa.
• UNGAYIMISI noma ushintshe imithi yakho ngaphandle kokukhuluma nomhlinzeki wakho kuqala.

Ungase uzwe ubuhlungu obuncane noma isitinyela lapho kufakwa inaliti. Ungase futhi uzizwe ushaywa yisiza ngemuva kokukhishwa kwegazi.

Lapho umphumela wokuhlolwa kwe-ALP uphezulu, kungadingeka ukuthi ube nokuhlolwa kwe-ALP isoenzyme. Lokhu kuhlolwa kuzosiza ekunqumeni ukuthi iyiphi ingxenye yomzimba ebangela amazinga aphezulu e-ALP.

Lokhu kuhlolwa kungasetshenziselwa ukuxilonga noma ukuqapha:

• Isifo samathambo
• Isifo sesibindi, i-gallbladder, noma i-bile duct
• Ubuhlungu esiswini
• Isifo sendlala Parathyroid
• Ukushoda kukavithamini D

Kungenziwa futhi ukuhlola ukusebenza kwesibindi nokubona ukuthi imithi oyithathayo ingasithinta kanjani isibindi sakho.

Inani elijwayelekile lenani eliphelele le-ALP lingama-unit amayunithi angama-44 kuya kwangama-147 ngelitha ngalinye (IU / L) noma u-0.73 kuye ku-2.45 ngemitha engaphansi yelitha (atkat / L). Ukuhlolwa kwe-ALP isoenzyme kungahle kube namanani ajwayelekile ahlukile.

Abantu abadala banamazinga aphansi e-ALP kunezingane. Amathambo asakhula akhiqiza amazinga aphezulu we-ALP. Ngesikhathi sokukhula okuthile, amazinga angaba phezulu njenge-500 IU / L noma i-835 µKat / L. Ngalesi sizathu, ukuhlolwa akuvamisile ukwenziwa ezinganeni, futhi imiphumela engajwayelekile ibhekisa kubantu abadala.

Imiphumela yokuhlolwa kwe-isoenzyme ingadalula ukuthi ukwanda ku-"bone" ALP noma "isibindi" ALP.

Ububanzi bamanani ajwayelekile bungahluka kancane phakathi kwamalabhorethri ahlukene. Khuluma nomhlinzeki wakho mayelana nencazelo yemiphumela yakho ethile yokuhlolwa.

Isibonelo esingenhla sikhombisa ibanga lesilinganiso elijwayelekile lemiphumela yalezi zivivinyo. Amanye ama-laboratories asebenzisa izilinganiso ezahlukahlukene noma angahlola izinhlobo ezahlukene.

Izinga le-ALP elingaphezu kokujwayelekile:

• Ukuvinjelwa kwe-biliary
• Isifo samathambo
• Ukudla ukudla okunamafutha uma unohlobo lwegazi O noma B
• Ukuphulukisa ukuphuka
• Isibindi
• Hyperparathyroidism
• Umdlavuza wegazi
• Isifo sesibindi
• I-Lymphoma
• Izicubu zamathambo e-Osteoblastic
• I-Osteomalacia
• Isifo sePaget
• Ama-Rickets
• I-Sarcoidosis

Amazinga aphansi kunokujwayelekile we-ALP:

• I-Hypophosphatasia
• Ukungondleki
• Ukushoda kwamaphrotheni
• Isifo sikaWilson

Amaleveli aphakeme nje kancane kunokujwayelekile kungenzeka angabi yinkinga ngaphandle uma kunezinye izimpawu zesifo noma inkinga yezokwelapha.

Ukuhlolwa kwe-alkaline phosphatase isoenzyme

• Ukuhlolwa kwegazi

IBerk PD, iKorenblat KM. Sondela esigulini nge-jaundice noma ngokuhlolwa kwesibindi okungavamile. Ku: IGoldman L, iSchafer AI, ama-eds. Imithi yeGoldman-Cecil. Umhla ka-25. IPhiladelphia, PA: Elsevier Saunders; 2016: isahluko 147.

UFogel EL, uSherman S. Izifo zesinyongo kanye namapayipi enyongo. Ku: IGoldman L, iSchafer AI, ama-eds. Imithi yeGoldman-Cecil. Umhla ka-25. IPhiladelphia, PA: Elsevier Saunders; 2016: isahluko 155.

UMartin P. Indlela eya esigulini esinesifo sesibindi. Ku: IGoldman L, iSchafer AI, ama-eds. Imithi yeGoldman-Cecil. Umhla ka-25. IPhiladelphia, PA: Elsevier Saunders; 2016: isahluko 146.

I-Weinstein RS. Osteomalacia namarickets. Ku: IGoldman L, iSchafer AI, ama-eds. Imithi yeGoldman-Cecil. Umhla ka-25. IPhiladelphia, PA: Elsevier Saunders; 2016: isahluko 244.