Ukuhlolwa kwe-vitamin D engu-25-hydroxy

Isivivinyo se-25-hydroxy vitamin D siyindlela enembile kunazo zonke yokulinganisa ukuthi uvithamini D omningi kangakanani emzimbeni wakho.

U-Vitamin D usiza ukulawula amazinga e-calcium ne-phosphate emzimbeni.

Kudingeka isampula yegazi.

Imvamisa, awudingi ukuzila ukudla. Kepha lokhu kuya nge-laboratory nendlela yokuhlola esetshenzisiwe. Landela noma imiphi imiyalelo yokuthi ungadli ngaphambi kokuhlolwa.

Lapho inaliti ifakwa ukudonsa igazi, abanye abantu bezwa ubuhlungu obulinganiselayo. Abanye bazizwa beshaywa noma betinyelwa kuphela. Ngemuva kwalokho, kungahle kube nokushaywa okuthile.

Lokhu kuhlolwa kwenziwa ukuthola ukuthi unovithamini D omningi noma omncane kakhulu egazini lakho. Ukuhlolwa kwabo bonke abantu abadala, noma ngabe bakhulelwe, ukuthola amazinga aphansi kavithamini D akuvamile kunconywa.

Kodwa-ke, ukuhlolwa kungenziwa kubantu abasengozini enkulu yokushoda kukavithamini D, njengalabo:

• Bangaphezu kweminyaka yobudala engama-65 (kokubili ukukhiqizwa kwesikhumba kukavithamini D nokufakwa kwesisu ku-vitamin D kuyehla njengoba sikhula)
• Ingabe ukhuluphele (noma ulahlekelwe isisindo ekuhlinzweni kwe-bariatric)
• Bathatha imithi ethile, efana ne-phenytoin
• Unesifo samathambo noma amathambo amancane
• Yiba nokukhanya kwelanga okulinganiselwe
• Unenkinga yokuthola amavithamini nezakhi zomzimba emathunjini abo, njengaleyo ene-ulcerative colitis, isifo se-Crohn, noma isifo se-celiac

Ububanzi obujwayelekile bukavithamini D bukalwa njengama-nanograms ngemililitha ngayinye (ng / mL). Ochwepheshe abaningi bancoma izinga eliphakathi kuka-20 no-40 ng / mL. Abanye bancoma izinga eliphakathi kuka-30 no-50 ng / mL.

Izibonelo ezingenhla yizilinganiso ezijwayelekile zemiphumela yalezi zivivinyo. Ububanzi bamanani ajwayelekile bungahluka kancane phakathi kwamalabhorethri ahlukene. Amanye amalabhoratri asebenzisa izilinganiso ezahlukahlukene noma avivinye amasampula ahlukile. Khuluma nodokotela wakho mayelana nencazelo yemiphumela yakho ethile yokuhlolwa, nokuthi ungadinga yini izengezo zikavithamini D.

• I-25 hydroxy vitamin D3 (cholecalciferol) i-vitamin D eyenziwe ngumzimba wakho noma oyithathe emthonjeni wezilwane (njengezinhlanzi ezinamafutha noma isibindi) noma i-cholecalciferol supplement.
• I-25 hydroxy vitamin D2 (ergocalciferol) yivithamini D oyithathe ekudleni okuqiniswe nge-vitamin D yesitshalo noma kusuka ku-ergocalciferol supplement.
• Ama-hormone amabili (i-ergo- ne-cholecalciferol) asebenza ngokufanayo emzimbeni. Inani elibalulekile inani eliphelele lamavithamini D angama-25 egazini lakho.

Izinga eliphansi kunokujwayelekile lingahle libe ngenxa yokushoda kukavithamini D, okungavela ku:

• Ukungabi bikho kwesikhumba ekukhanyeni kwelanga, isikhumba esinombala omnyama, noma ukusetshenziswa okungaguquguquki kwesikrini selanga esiphezulu se-SPF
• Ukungabi novithamini D owanele ekudleni
• Izifo zesibindi nezinso
• Ukumuncwa kokudla okungampofu
• Ukusetshenziswa kwemithi ethile, kufaka phakathi i-phenytoin, i-phenobarbital, ne-rifampin
• Ukumuncwa okungavumelekile kukavithamini D ngenxa yokuguga, ukuhlinzwa okwehlisa isisindo, noma izimo lapho amafutha angangeni khona kahle

Izinga eliphansi le-vitamin D livame kakhulu ezinganeni zase-Afrika zaseMelika (ikakhulukazi ebusika), kanye nasezinsaneni ezinceliswa ibele kuphela.

Izinga eliphakeme kunokujwayelekile lingahle libe ngenxa ye-vitamin D eyeqile, isimo esibizwa nge-hypervitaminosis D. Lokhu kuvame kakhulu ukubangelwa ukuthatha uvithamini omningi kakhulu. Kungadala i-calcium eningi emzimbeni (i-hypercalcemia). Lokhu kuholela ezimpawu eziningi nasekulimaleni kwezinso.

Kunengozi encane ethintekayo ekuthatheni igazi lakho. Imithambo nemithambo yegazi kuyahluka ngosayizi komunye umuntu kuya kolunye uhlangothi lomzimba kuya kolunye. Ukuthatha igazi kwabanye abantu kungaba nzima kakhulu ukwedlula kwabanye.

Ezinye izingozi ezihambisana nokudonswa igazi zincane, kepha zingafaka:

• Ukopha ngokweqile
• Ukubhoboza okuningi ukuthola imithambo
• Ukuquleka noma uzizwe unekhanda elincane
• I-hematoma (ukuqoqwa kwegazi ngaphansi kwesikhumba)
• Ukutheleleka (ingozi encane noma kunini lapho isikhumba siphukile)

Ukuhlolwa kwe-vitamin D 25-OH; I-Calcidiol; Ukuhlolwa kwe-25-hydroxycholecalciferol

• Ukuhlolwa kwegazi

I-Bouillon R. Vitamin D: kusuka ku-photosynthesis, metabolism, kanye nesenzo kuzinhlelo zokusebenza zomtholampilo. Ku: Jameson JL, De Groot LJ, de Kretser DM, et al, abahleli. I-Endocrinology: Eyabantu Abadala Neyengane. Umhla wesi-7. IPhiladelphia, PA: Elsevier Saunders; 2016: isahluko 59.

IChernecky CC, iBerger BJ. Uvithamini D (cholecalciferol) - i-plasma noma i-serum. Ku: IChernecky CC, iBerger BJ, ama-eds. Ukuhlolwa Kwelebhu kanye Nezinqubo Zokuxilonga. Umhlaka 6. ISt Louis, MO: Elsevier Saunders; 2013: 1182-1183.

LeFevre ML; I-US Preventive Services Task Force. Ukuhlolwa kokushoda kukavithamini D kubantu abadala: Isitatimende sezincomo ze-US Preventive Services Task Force. U-Ann Intern Med. 2015; 162 (2): 133-140. I-PMID: 25419853 pubmed.ncbi.nlm.nih.gov/25419853/.