Ukuhlolwa kwe-urine protein electrophoresis

Isivivinyo se-urine protein electrophoresis (UPEP) sisetshenziselwa ukulinganisa ukuthi angakanani amaprotheni athile asemchameni.

Isampula yomchamo wokubamba ehlanzekile iyadingeka. Indlela yokubamba ehlanzekile isetshenziselwa ukuvimbela amagciwane avela endondeni noma esithweni sangasese ekungeneni kusampula yomchamo. Ukuqoqa umchamo wakho, umhlinzeki wezokunakekelwa kwempilo angakunika ikhithi ekhethekile yokubamba ehlanzekile equkethe isisombululo sokuhlanza kanye nokusula okuyinyumba. Landela imiyalo ngqo.

Ngemuva kokunikeza isampula yomchamo, ithunyelwa elabhorethri. Lapho, isazi selabhorethri sizobeka isampula lomchamo ephepheni elikhethekile bese sisebenzisa amandla kagesi. Amaprotheni anyakaza futhi akha amabhendi abonakalayo. Lokhu kuveza inani elijwayelekile leprotheyini ngalinye.

Umhlinzeki wakho angakutshela ukuthi uyeke ukuthatha imishanguzo ethile engaphazamisa ukuhlolwa. Imithi engathinta imiphumela yokuhlolwa ifaka phakathi:

• I-chlorpromazine
• Ama-Corticosteroids
• Isoniazid
• I-Neomycin
• Phenacemide
• Ama-salicylates
• AmaSulfonamides
• I-Tolbutamide

Ungayeki ukuthatha noma imuphi umuthi ngaphandle kokuqala ukhulume nomhlinzeki wakho.

Lokhu kuhlolwa kuhilela ukuchama okuvamile kuphela. Akukho ukungakhululeki.

Imvamisa awekho amaprotheni, noma inani elincane kuphela lamaprotheni emchameni. Inani eliphakeme ngokungajwayelekile lamaprotheni emchameni kungaba uphawu lokuphazamiseka okuningi okuhlukile.

Kunganconywa i-UPEP ukusiza ukuthola imbangela yamaprotheni emchameni. Noma kungenziwa njengokuhlolwa kokuhlola ukukala amanani ahlukahlukene ezinhlobo ezahlukahlukene zamaprotheni emchameni. I-UPEP ithola izinhlobo ezimbili zamaprotheni: i-albumin nama-globulin.

Akukho manani abalulekile ama-globulin atholakala emchameni. I-albumin yomchamo ingaphansi kuka-5 mg / dL.

Ububanzi bamanani ajwayelekile bungahluka kancane phakathi kwamalabhorethri ahlukene. Amanye amalebhu asebenzisa izilinganiso ezahlukahlukene noma avivinye izinhlobo ezihlukile. Khuluma nodokotela wakho mayelana nencazelo yemiphumela yakho ethile yokuhlolwa.

Uma isampula yomchamo inenani elikhulu lama-globulin noma ngaphezulu kwezinga elijwayelekile le-albhamuin, kungasho noma yikuphi okulandelayo:

• Ukuvuvukala okukhulu
• Amaprotheni angajwayelekile ezakhiweni nasezithweni (amyloidosis)
• Ukwehla kokusebenza kwezinso
• Isifo sezinso ngenxa yesifo sikashukela (nephropathy yesifo sikashukela)
• Ukuhluleka kwezinso
• Uhlobo lomdlavuza wegazi obizwa nge-multiple myeloma
• Iqembu lezimpawu ezibandakanya amaprotheni emchameni, izinga eliphansi lamaprotheni egazini, ukuvuvukala (nephrotic syndrome)
• Ukutheleleka okunamandla komgudu womchamo

Azikho izingozi ngalokhu kuhlolwa.

Umchamo wamaprotheni electrophoresis; PHAKAMA; I-myeloma eminingi - UPEP; I-Waldenström macroglobulinemia - UPEP; I-Amyloidosis - UPEP

• Uhlelo lwesilisa lomchamo

IChernecky CC, iBerger BJ. Amaprotheni electrophoresis - umchamo. Ku: IChernecky CC, iBerger BJ, ama-eds. Ukuhlolwa Kwelabhoratri Nezinqubo Zokuxilonga. Umhlaka 6. ISt Louis, MO: Elsevier Saunders; 2013: 920-922.

UMcPherson RA. Amaprotheni athile. Ku: McPherson RA, Pincus MR, abahleli. UHenry’s Clinical Diagnosis and Management by Laboratory Methods. Umhla ka-23. ISt Louis, MO: Elsevier; 2017: isahluko 19.

URajkumar SV, iDispenzieri A. I-myeloma eminingi kanye nokuphazamiseka okuhlobene. Ku: Niederhuber JE, Armitage JO, Kastan MB, Doroshow JH, Tepper JE, abahleli. I-Abeloff’s Clinical Oncology. Umhlaka 6. IPhiladelphia, PA: Elsevier; 2020: isahluko 101.