Ukuhlolwa kwemvume ye-Creatinine

Ukuhlolwa kwe-creatinine clearance kusiza ukuhlinzeka ngolwazi mayelana nokuthi izinso zisebenza kahle kangakanani. Ukuhlolwa kuqhathanisa ileveli ye-creatinine emchameni nezinga le-creatinine egazini.

Lokhu kuhlolwa kudinga isampula yomchamo nesampula segazi. Uzoqoqa umchamo wakho amahora angama-24 bese uthathwa igazi. Landela imiyalo ngqo. Lokhu kuqinisekisa imiphumela enembile.

Umhlinzeki wakho wezokunakekelwa kwempilo angakucela ukuthi umise okwesikhashana noma yimiphi imithi engathinta imiphumela yokuhlolwa. Lokhu kufaka phakathi eminye imithi elwa namagciwane kanye nemithi ye-asidi esiswini. Qiniseka ukuthi utshela umhlinzeki wakho ngayo yonke imithi oyiphuzayo.

Ungayeki ukuthatha noma imuphi umuthi ngaphambi kokukhuluma nomhlinzeki wakho.

Ukuhlolwa komchamo kufaka kuphela ukuchama okujwayelekile. Akukho ukungakhululeki.

Lapho inaliti ifakwa ukudonsa igazi, abanye abantu bezwa ubuhlungu obulinganiselayo. Abanye bazizwa beshaywa noma betinyelwa kuphela. Ngemuva kwalokho, kungahle kube nokushaywa okuthile noma ukulimazeka okuncane. Lokhu maduzane kuyaphela.

I-Creatinine ingumkhiqizo wemfucuza wamakhemikhali we-creatine. I-Creatine iyikhemikhali elenziwa ngumzimba ukunikezela ngamandla, ikakhulukazi emisipheni.

Ngokuqhathanisa ileveli ye-creatinine emchameni nezinga le-creatinine egazini, ukuhlolwa kwe-creatinine clearance the glomerular filtration rate (GFR). I-GFR iyisilinganiso sokuthi izinso zisebenza kahle kangakanani, ikakhulukazi izingxenye zokuhlunga izinso. Lezi zingxenye zokuhlunga zibizwa nge-glomeruli.

I-Creatinine iyasuswa, noma isuliwe, emzimbeni ngokuphelele yizinso. Uma ukusebenza kwezinso kungavamile, izinga le-creatinine liyakhuphuka egazini ngoba i-creatinine encane ikhishwa ngomchamo.

Ukususwa kuvame ukulinganiswa njengamamililitha ngomzuzu (mL / min) noma ama-milliliters ngomzuzwana (mL / s). Amanani ajwayelekile yilawa:

• Owesilisa: 97 kuya ku-137 ml / min (1.65 kuye ku-2.33 mL / s).
• Owesifazane: 88 kuya ku-128 mL / min (14.96 kuye ku-2.18 mL / s).

Ububanzi bamanani ajwayelekile bungahluka kancane phakathi kwamalabhorethri ahlukene. Amanye amalebhu asebenzisa izilinganiso ezahlukahlukene noma avivinye amasampula ahlukile. Khuluma nodokotela wakho ukuze wazi ngencazelo yemiphumela yakho ethile yokuhlolwa.

Imiphumela engajwayelekile (ngaphansi kokuvunyelwa kwe-creatinine ejwayelekile) ingakhombisa:

• Izinkinga zezinso, njengokulimala kwamangqamuzana e-tubule
• Ukuhluleka kwezinso
• Ukugeleza kwegazi okuncane kakhulu kuya ezinso
• Ukulimala kwamayunithi wokuhlunga wezinso
• Ukulahlekelwa uketshezi lomzimba (ukoma)
• Isithintelo esidayisa isinye
• Ukwehluleka kwenhliziyo

Kunengozi encane ethintekayo ekuthatheni igazi lakho. Imithambo nemithambo yegazi kuyahluka ngosayizi komunye umuntu kuya kolunye uhlangothi lomzimba kuya kolunye. Ukuthatha igazi kwabanye abantu kungaba nzima kakhulu ukwedlula kwabanye.

Ezinye izingozi ezihambisana nokudonswa igazi zincane, kepha zingafaka:

• Ukopha ngokweqile
• Ukuquleka noma uzizwe unekhanda elincane
• Ukubhoboza okuningi ukuthola imithambo
• I-hematoma (ukuqoqwa kwegazi ngaphansi kwesikhumba)
• Ukutheleleka (ingozi encane noma kunini lapho isikhumba siphukile)

Imvume ye-Serum creatinine; Umsebenzi wezinso - imvume ye-creatinine; Umsebenzi we-renal - imvume ye-creatinine

• Ukuhlolwa kwe-Creatinine

I-Landry DW, iBazari H. Indlela eya esigulini esinesifo so-renal. Ku: IGoldman L, iSchafer AI, ama-eds. Imithi yeGoldman-Cecil. Umhla ka-26. IPhiladelphia, PA: Elsevier; 2020: isahluko 106.

I-Oh MS, i-Briefel G. Ukuhlolwa kokusebenza kwezinso, amanzi, ama-electrolyte, ne-acid-base balance. Ku: McPherson RA, Pincus MR, abahleli. UHenry’s Clinical Diagnosis and Management by Laboratory Methods. Umhla ka-23. ISt Louis, MO: Elsevier; I-2017: isahluko 14.