AmaCatecholamine - umchamo

I-Catecholamines ngamakhemikhali enziwa izicubu zemizwa (kufaka phakathi ubuchopho) kanye ne-adrenal gland.

Izinhlobo eziyinhloko zama-catecholamine yi-dopamine, i-norepinephrine, ne-epinephrine. Lawa makhemikhali ahlahlela kwezinye izinto, ashiya umzimba wakho ngomchamo wakho.

Ukuhlolwa komchamo kungenziwa ukukala izinga lama-catecholamine emzimbeni wakho. Ukuhlolwa okuhlukile komchamo kungenziwa ukukala izinto ezihambisanayo.

AmaCatecholamine nawo angalinganiswa ngokuhlolwa kwegazi.

Kulesi sivivinyo, kufanele uqoqe umchamo wakho esikhwameni esikhethekile noma esitsheni njalo lapho uchama isikhathi samahora angama-24.

• Ngosuku lokuqala, chamela indlu yangasese lapho uvuka ekuseni bese uwulahla lowo mchamo.
• Chamela esitsheni esikhethekile njalo uma usebenzisa indlu yokugezela amahora angama-24 alandelayo. Yigcine esiqandisini noma endaweni epholile ngesikhathi sokuqoqa.
• Ngosuku 2, chamela esitsheni ekuseni futhi lapho uvuka.
• Faka ilebula esitsheni negama lakho, usuku, isikhathi sokuphothulwa, bese usibuyisela njengokuyalelwe.

Enganeni, geza kahle indawo lapho umchamo uphuma khona emzimbeni.

• Vula isikhwama sokuqoqa umchamo (isikhwama sepulasitiki esinephepha lokunamathisela ekugcineni).
• Kwabesilisa, faka wonke umthondo esikhwameni bese unamathisela ukunamathela esikhunjeni.
• Kwabesifazane, beka isikhwama phezu kwama-labia.
• Inabukeni njengenjwayelo phezu kwesikhwama esivikelekile.

Le nqubo ingathatha imizamo embalwa. Ingane esebenzayo ingahambisa isikhwama esidala ukuthi umchamo ungene emanabukeni.

Hlola usana kaningi bese ushintsha isikhwama ngemuva kokuthi usana seluchamele kulo. Khipha umchamo esikhwameni ungene esitsheni esihlinzekwe ngumhlinzeki wakho wezokunakekelwa kwempilo.

Hambisa isampula elabhorethri noma kumhlinzeki wakho ngokushesha okukhulu.

Ukucindezeleka nokuvivinya umzimba okunzima kungathinta imiphumela yokuhlolwa.

Okunye ukudla kungakhuphula ama-catecholamine emchameni wakho. Ungadinga ukugwema lokhu kudla neziphuzo ezilandelayo izinsuku ezimbalwa ngaphambi kokuhlolwa:

• Ubhanana
• Ushokoledi
• Izithelo ze-Citrus
• Ukhokho
• Ikhofi
• Ilayisensi
• Itiye
• I-Vanilla

Imithi eminingi ingaphazamisa imiphumela yokuhlolwa.

• Umhlinzeki wakho uzokutshela uma udinga ukuyeka ukuthatha noma yimiphi imithi ngaphambi kokwenza lokhu kuhlolwa.
• UNGAYIMISI noma ushintshe imithi yakho ngaphandle kokukhuluma nomhlinzeki wakho kuqala.

Isivivinyo sihilela ukuchama okujwayelekile kuphela, futhi akukho ukungaphatheki kahle.

Ukuhlolwa kuvame ukwenziwa ukuthola isimila sendlala ye-adrenal ebizwa nge-pheochromocytoma. Ingasetshenziselwa ukuxilonga i-neuroblastoma. Amazinga e-urine catecholamine ayanda kubantu abaningi abane-neuroblastoma.

Ukuhlolwa komchamo wama-catecholamine kungasetshenziswa futhi ukuqapha labo abathola ukwelashwa ngalezi zimo.

Onke ama-catecholamines ahlukaniswe abe yizinto ezingasebenzi ezivela kumchamo:

• I-Dopamine iba yi-homovanillic acid (HVA)
• INorepinephrine iba yi-normetanephrine ne-vanillylmandelic acid (VMA)
• I-Epinephrine iba yi-metanephrine ne-VMA

Amanani ajwayelekile alandelayo yinani lezinto ezitholakala emchameni esikhathini samahora angama-24:

• I-Dopamine: ama-micrograms angama-65 kuya kwangu-400 (mcg) / amahora angama-24 (420 kuya ku-2612 nmol / amahora angu-24)
• I-Epinephrine: 0.5 kuya ku-20 mcg / amahora angu-24
• I-Metanephrine: amahora angama-24 kuya kwangu-96 mcg / 24 (amanye ama-laboratories anika ibanga njengama-140 kuya kuma-785 mcg / amahora angu-24)
• I-Norepinephrine: 15 kuya ku-80 mcg / amahora angu-24 (89 kuye ku-473 nmol / amahora angu-24)
• I-Normetanephrine: amahora angama-75 kuya kwangu-375 mcg / 24
• Ingqikithi yama-catecholamines womchamo: amahora angu-14 kuya kwangu-110 mcg / 24
• I-VMA: 2 kuya ku-7 milligrams (mg) / amahora angu-24 (10 kuye ku-35 mcmol / amahora angu-24)

Ububanzi bamanani ajwayelekile bungahluka kancane phakathi kwamalabhorethri ahlukene. Khuluma nomhlinzeki wakho mayelana nencazelo yemiphumela yakho ethile yokuhlolwa.

Izibonelo ezingenhla zibonisa izilinganiso ezivamile zemiphumela yalezi zivivinyo. Amanye ama-laboratories asebenzisa izilinganiso ezahlukahlukene noma angahlola izinhlobo ezahlukene.

Amazinga aphakeme ama-catecholamine we-urinary angakhombisa:

• Ukukhathazeka okukhulu
• I-Ganglioneuroblastoma (engavamile kakhulu)
• I-Ganglioneuroma (engavamile kakhulu)
• I-Neuroblastoma (engavamile)
• I-Pheochromocytoma (kuyaqabukela)
• Ukucindezeleka okukhulu

Isivivinyo singenzelwa futhi:

• Ama-endocrine neoplasia amaningi (AMADODA) II

Azikho izingozi.

Ukudla okuningana nezidakamizwa, kanye nokusebenza komzimba kanye nengcindezi, kungathinta ukunemba kwalesi sivivinyo.

Ukuhlolwa kwe-Dopamine - umchamo; I-Epinephrine - ukuhlolwa komchamo; Ukuhlolwa kwe-Adrenalin - umchamo; Umchamo metanephrine; ENormetanephrine; I-norepinephrine - ukuhlolwa komchamo; Ama-catecholamines womchamo; I-VMA; I-HVA; I-Metanephrine; I-Homovanillic acid (HVA)

• Umgudu womchamo wabesifazane
• Umgudu womchamo wabesilisa
• Ukuhlolwa komchamo weCatecholamine

UGuber HA, uFarag AF. Ukuhlolwa komsebenzi we-endocrine. Ku: McPherson RA, Pincus MR, abahleli. UHenry’s Clinical Diagnosis and Management by Laboratory Methods. Umhla ka-23. ISt Louis, MO: Elsevier; 2017: isahluko 24.

WF osemncane. I-Adrenal medulla, i-catecholamines, ne-pheochromocytoma. Ku: IGoldman L, iSchafer AI, ama-eds. Imithi yeGoldman-Cecil. Umhla ka-25. IPhiladelphia, PA: Elsevier Saunders; 2016: isahluko 228.