Ukuhlolwa kwegazi le-Antithrombin III

I-Antithrombin III (AT III) yiprotheni esiza ukulawula ukunqamuka kwegazi. Ukuhlolwa kwegazi kunganquma inani le-AT III elikhona emzimbeni wakho.

Kudingeka isampula yegazi.

Imithi ethile ingathinta imiphumela yokuhlolwa. Umhlinzeki wakho wezokunakekelwa kwempilo angakutshela ukuthi uyeke ukuthatha imithi ethile noma wehlise umthamo wabo ngaphambi kokuhlolwa. Ungayeki ukuthatha noma imuphi umuthi ngaphambi kokukhuluma nomhlinzeki wakho.

Lapho inaliti ifakwa ukudonsa igazi, abanye abantu bezwa ubuhlungu obulinganiselayo. Abanye bazizwa beshaywa noma betinyelwa kuphela. Ngemuva kwalokho, kungahle kube nokushaywa okuthile noma ukulimazeka okuncane. Lokhu maduzane kuyaphela.

Umhlinzeki wakho anga-oda lokhu kuhlolwa uma uphindaphinde amahlule egazi noma uma umuthi wokuncipha kwegazi ungasebenzi.

Ububanzi bamanani ajwayelekile bungahluka kancane phakathi kwamalabhorethri ahlukene. Khuluma nomhlinzeki wakho mayelana nencazelo yemiphumela yakho ethile yokuhlolwa.

I-AT III engaphansi kokujwayelekile ingasho ukuthi unengozi eyengeziwe yokujiya kwegazi. Lokhu kungenzeka uma ingekho i-AT III eyanele egazini lakho, noma uma kune-AT III eyanele egazini lakho, kepha i-AT III ayisebenzi kahle futhi ayisebenzi kangako.

Imiphumela engajwayelekile kungenzeka ingaveli uze ube mdala.

Izibonelo zezinkinga ezihambisana nokwanda kwe-clotting yegazi yilezi:

• I-thrombosis ejulile ye-venous
• I-phlebitis (ukuvuvukala kwe-vein)
• I-pulmonary embolus (igazi elihamba liye emaphashini)
• I-thrombophlebitis (ukuvuvukala kwe-vein nokwakheka kwe-clot)

Ngaphansi kune-AT III ejwayelekile kungenzeka kungenxa yokuthi:

• Ukufakelwa komnkantsha wethambo
• Kusatshalaliswe i-coagulation ye-intravascular (DIC)
• Ukuntuleka kwe-AT III, isimo esizuzwe njengefa
• Isibindi sokuqina kwesibindi
• I-Nephrotic syndrome

Okuphakeme kunejwayelekile i-AT III kungenzeka kungenxa yokuthi:

• Ukusetshenziswa kwama-anabolic steroids
• Ukuphazamiseka kwegazi (hemophilia)
• Ukufakelwa kwezinso
• Izinga eliphansi likavithamini K

Kunengozi encane ethintekayo ekuthatheni igazi lakho. Imithambo nemithambo iyehluka ngobukhulu ukusuka komunye umuntu iye komunye, futhi kusukela kolunye uhlangothi lomzimba kuye kolunye. Ukuthola isampula yegazi kwabanye abantu kungaba nzima kakhulu ukwedlula kwabanye.

Ezinye izingozi zingafaka:

• Ukopha ngokweqile
• Ukuquleka noma uzizwe unekhanda elincane
• Ukubhoboza okuningi ukuthola imithambo
  
• I-hematoma (ukuqoqwa kwegazi ngaphansi kwesikhumba)
• Ukutheleleka (ingozi encane noma kunini lapho isikhumba siphukile)

I-Antithrombin; AT III; NGO-3; I-antithrombin III esebenzayo; Ukuphazamiseka kokuvala - AT III; I-DVT - AT III; I-vein thrombosis ejulile - AT III

U-Anderson JA, uKogg KE, Weitz JI. I-Hypercoagulation ithi. Ku: Hoffman R, Benz EJ, Silberstein LE, et al, ama-eds. I-Hematology: Izimiso Eziyisisekelo Nokuzijwayeza. Umhla wesi-7. IPhiladelphia, PA: Elsevier; 2018: isahluko 140.

IChernecky CC, iBerger BJ. Ukuhlolwa kwe-Antithrombin III (AT-III) - ukuxilonga. Ku: IChernecky CC, iBerger BJ, ama-eds. Ukuhlolwa Kwelabhoratri Nezinqubo Zokuxilonga. Umhlaka 6. ISt Louis, MO: Elsevier Saunders; 2013: 156-157.

UNapolitano M, uSchmaier AH, uKessler CM. I-Coagulation kanye ne-fibrinolysis. Ku: McPherson RA, Pincus MR, abahleli. UHenry’s Clinical Diagnosis and Management by Laboratory Methods. Umhla ka-23. ISt Louis, MO: Elsevier; 2017: isahluko 39.