Ukuhlolwa kwe-T3

I-Triiodothyronine (T3) iyihomoni yegilo. Idlala indima ebalulekile ekulawuleni komzimba we-metabolism (izinqubo eziningi ezilawula izinga lomsebenzi kumaseli nezicubu).

Ukuhlolwa kwelabhorethri kungenziwa ukukala inani le-T3 egazini lakho.

Kudingeka isampula yegazi.

Umhlinzeki wakho wezokunakekelwa kwempilo uzokutshela uma kudingeka uyeke ukuthatha noma yimiphi imithi ngaphambi kokuhlolwa okungathinta imiphumela yakho yokuhlolwa. UNGAYEKISI ukuthatha noma imuphi umuthi ngaphandle kokuqala ukhulume nomhlinzeki wakho.

Izidakamizwa ezingakhuphula izilinganiso ze-T3 zifaka:

• Amaphilisi okuvimbela inzalo
• Clofibrate
• Ama-Estrogens
• I-Methadone
• Imithi ethile yamakhambi

Izidakamizwa ezinganciphisa izilinganiso ze-T3 zifaka:

• Amiodarone
• Ama-Anabolic steroids
• I-Androgens
• Izidakamizwa ze-Antithyroid (ngokwesibonelo, i-propylthiouracil ne-methimazole)
• ILithium
• Phenytoin
• I-Propranolol

Lapho inaliti ifakwa ukudonsa igazi, abanye abantu bezwa ubuhlungu obulinganiselayo. Abanye bazizwa beshaywa noma betinyelwa kuphela. Ngemuva kwalokho, kungahle kube nokushaywa okuthile noma ukulimazeka okuncane. Lokhu maduzane kuyaphela.

Lokhu kuhlolwa kwenziwa ukuhlola umsebenzi wakho wegilo. Umsebenzi we-thyroid uncike esenzweni se-T3 namanye ama-hormone, kufaka phakathi i-hormone evuselela i-thyroid (TSH) ne-T4.

Kwesinye isikhathi kungasiza ukukala i-T3 ne-T4 lapho uhlola ukusebenza kwe-thyroid.

Ukuhlolwa okuphelele kwe-T3 kukala i-T3 ehlanganiswe namaphrotheni futhi intanta mahhala egazini.

Ukuhlolwa kwamahhala kwe-T3 kukala i-T3 entanta mahhala egazini. Ukuhlolwa kwe-T3 yamahhala ngokuvamile akunembe kangako kunokwengqikithi ye-T3.

Umhlinzeki wakho angancoma lokhu kuhlolwa uma unezimpawu zesifo se-thyroid, kufaka phakathi:

• Indlala ye-pituitary ayivezi amanani ajwayelekile amanye noma wonke ama-hormone ayo (i-hypopituitarism)
• Indlala yegilo eyeqile (hyperthyroidism)
• Indlala yegilo engasebenzi kahle (hypothyroidism)
• Ukuthatha imithi ye-hypothyroidism

Ububanzi bamanani ajwayelekile yile:

• Ingqikithi ye-T3 - 60 kuya ku-180 nanograms nge-deciliter ngayinye (ng / dL), noma ama-nanomoles angu-0.9 kuye ku-2.8 ngelitha ngalinye (nmol / L)
• Amaphikrama ama-T3 - 130 kuya ku-450 amahhala nge-desilitha (pg / dL), noma ngo-2.0 kuye ku-7.0 ama-picomoles ngelitha ngalinye (pmol / L)

Ububanzi bamanani ajwayelekile bungahluka kancane phakathi kwamalabhorethri ahlukene. Amanye amalebhu asebenzisa izilinganiso ezahlukahlukene noma avivinye izinhlobo ezihlukile. Khuluma nomhlinzeki wakho mayelana nencazelo yemiphumela yakho ethile yokuhlolwa.

Amanani ajwayelekile aqondene nobudala babantu abangaphansi kweminyaka yobudala engama-20. Buza kumhlinzeki wakho ngemiphumela yakho ethile.

Izinga eliphezulu ukwedlula elejwayelekile le-T3 kungaba uphawu lwe:

• Indlala yegilo eyeqile (ngokwesibonelo, isifo se-Graves)
• I-T3 thyrotoxicosis (engavamile)
• I-goiter nodular enobuthi
• Ukuthatha imithi ye-thyroid noma izithako ezithile (ezivamile)
• Isifo sesibindi

Izinga eliphakeme le-T3 lingenzeka ekukhulelweni (ikakhulukazi ngokugula kwasekuseni ekupheleni kwe-trimester yokuqala) noma ngokusebenzisa amaphilisi okulawula ukubeletha noma i-estrogen.

Izinga eliphansi kunokujwayelekile lingahle libe ngenxa ye:

• Izifo zesikhashana esifushane noma ezinye zesikhathi eside
• I-Thyroiditis (ukuvuvukala noma ukuvuvukala kwendlala yegilo - isifo sikaHashimoto yilona hlobo oluvame kakhulu)
• Indlala
• Indlala yegilo engasebenzi

Ukushoda kwe-Selenium kudala ukwehla ekuguqulweni kwe-T4 kuya ku-T3, kepha akucaci ukuthi lokhu kuholela emazingeni aphansi kunejwayelekile we-T3 kubantu.

Kunobungozi obuncane obubandakanyekile ekuthatheni igazi lakho.Imithambo yegazi nemithambo yegazi iyehluka ngosayizi komunye umuntu iye kolunye uhlangothi nangolunye uhlangothi lomzimba. Ukuthola isampula yegazi kwabanye abantu kungaba nzima kakhulu ukwedlula kwabanye.

Ezinye izingozi ezihambisana nokudonswa igazi zincane, kepha zingafaka:

• Ukopha ngokweqile
• Ukuquleka noma uzizwe unekhanda elincane
• Ukubhoboza okuningi ukuthola imithambo
• I-hematoma (i-blood buildup ngaphansi kwesikhumba)
• Ukutheleleka (ingozi encane noma kunini lapho isikhumba siphukile)

Triiodothyronine; T3 radioimmunoassay; I-goiter nodular enobuthi - T3; Indlala yegilo - T3; I-Thyrotoxicosis - i-T3; Isifo samathuna - T3

• Ukuhlolwa kwegazi

UGuber HA, uFarag AF. Ukuhlolwa komsebenzi we-endocrine. Ku: McPherson RA, Pincus MR, abahleli. UHenry’s Clinical Diagnosis and Management by Laboratory Methods. Umhla ka-23. ISt Louis, MO: Elsevier; 2017: isahluko 24.

UKim G, uNandi-Munshi D, uDiblasi CC. Ukuphazamiseka kwendlala yegilo. Ku: Gleason CA, Juul SE, ama-eds. Izifo zika-Avery Zomntwana osanda kuzalwa. Umhlaka 10. IPhiladelphia, PA: Elsevier; 2018: isahluko 98.

USalvatore D, uCohen R, uKopp PA, uLarsen PR. I-pathophysiology ye-thyroid nokuhlolwa kokuxilongwa. Ku: Melmed S, Auchus RJ, Goldfine AB, Koenig RJ, Rosen CJ, abahleli. Incwadi kaWilliams ye-Endocrinology. Umhlaka 14. IPhiladelphia, PA: Elsevier; 2020: isahluko 11.

I-Weiss RE, Refetoff S. Ukuhlolwa komsebenzi we-Thyroid. Ku: Jameson JL, De Groot LJ, de Kretser DM, et al, abahleli. I-Endocrinology: Eyabantu Abadala Neyengane. Umhla wesi-7. IPhiladelphia, PA: Elsevier Saunders; 2016: isahluko 78.