Ukuhlolwa kwegazi likaRenin

Ukuhlolwa kwe-renin kukala izinga le-renin egazini.

Kudingeka isampula yegazi.

Imithi ethile ingathinta imiphumela yalokhu kuhlolwa. Umhlinzeki wakho wokunakekelwa kwezempilo uzokutshela uma udinga ukuyeka ukusebenzisa noma imiphi imithi. UNGAYIMISI noma imuphi umuthi ngaphambi kokukhuluma nomhlinzeki wakho.

Imithi engathinta izilinganiso ze-renin ifaka phakathi:

• Amaphilisi okuvimbela inzalo.
• Izidakamizwa zomfutho wegazi.
• Imithi evula imithambo yegazi (vasodilators). Lezi zivame ukusetshenziselwa ukwelapha umfutho wegazi ophakeme noma ukwehluleka kwenhliziyo.
• Amaphilisi wamanzi (isisu).

Umhlinzeki wakho angakuyala ukuthi ubeke umkhawulo ekudleni kwakho kwe-sodium ngaphambi kokuhlolwa.

Yazi ukuthi izinga le-renin lingathinteka ngokukhulelwa, kanye nesikhathi sosuku nesimo somzimba lapho kudonswa igazi.

Lapho inaliti ifakwa ukudonsa igazi, abanye abantu bezwa ubuhlungu obulinganiselayo. Abanye bazizwa behlatshwa noma bezwa nje kuphela. Ngemuva kwalokho, kungahle kube nokushaywa okuthile noma ukulimazeka okuncane. Lokhu maduzane kuyaphela.

URenin uyiprotheni (i-enzyme) ekhishwa ngamangqamuzana wezinso akhethekile uma wehla ngosawoti (isodiyamu) noma ivolumu ephansi yegazi. Imvamisa, ukuhlolwa kwegazi kwe-renin kwenziwa ngasikhathi sinye nokuhlolwa kwegazi le-aldosterone ukubala i-renin ezingeni le-aldosterone.

Uma une-high blood pressure, udokotela wakho anga-oda ukuhlolwa kwe-renin ne-aldosterone ukusiza ukuthola imbangela yengcindezi yakho yegazi ephakeme. Imiphumela yokuhlolwa ingasiza ekuqondiseni udokotela wakho ekukhetheni ukwelashwa okufanele.

Ngokudla okujwayelekile kwe-sodium, ibanga lenani elijwayelekile lingu-0.6 kuye ku-4.3 ng / mL / ihora (0.6 kuye ku-4.3 µg / L / ihora). Ngokudla okuphansi kwe-sodium, ibanga lenani elijwayelekile lingu-2.9 kuya ku-24 ng / mL / ihora (2.9 kuya ku-24 µg / L / ihora).

Ububanzi bamanani ajwayelekile bungahluka kancane phakathi kwamalabhorethri ahlukene. Amanye amalebhu asebenzisa izilinganiso ezahlukahlukene noma avivinye amasampula ahlukile. Khuluma nodokotela wakho mayelana nencazelo yemiphumela yakho ethile yokuhlolwa.

Izinga eliphakeme le-renin lingabangelwa:

• Izindlala ze-Adrenal ezingenzi amahomoni anele (i-Addison isifo noma okunye ukungasebenzi kahle kwe-adrenal gland)
• Ukopha (ukopha)
• Ukwehluleka kwenhliziyo
• Umfutho wegazi ophakeme obangelwa ukuncipha kwemithambo yezinso (umfutho wegazi ophakeme wokuqina)
• Ukulimala kwesibindi nokusebenza kwesibindi okubi (i-cirrhosis)
• Ukulahlekelwa uketshezi lomzimba (ukoma)
• Ukulimala kwezinso okudala i-nephrotic syndrome
• Izimila zezinso ezikhiqiza i-renin
• Umfutho wegazi ongazelelwe futhi ophakeme kakhulu (umfutho wegazi opholile)

Izinga eliphansi le-renin lingabangelwa:

• Izindlala ze-Adrenal ezikhipha i-aldosterone hormone eningi kakhulu (i-hyperaldosteronism)
• Umfutho wegazi ophezulu ozwela usawoti
• Ukwelashwa nge-antidiuretic hormone (ADH)
• Ukwelashwa ngemithi ye-steroid eyenza ukuthi umzimba ugcine usawoti

Kunengozi encane ethintekayo ekuthatheni igazi lakho. Imithambo nemithambo yegazi kuyahluka ngosayizi kusuka kwesiguli kuya kwesinye nokusuka kolunye uhlangothi lomzimba kuye kolunye. Ukuthatha igazi kwabanye abantu kungaba nzima kakhulu ukwedlula kwabanye.

Ezinye izingozi ezihambisana nokudonswa igazi zincane kepha zingafaka:

• Ukopha ngokweqile
• Ukuquleka noma uzizwe unekhanda elincane
• Ukubhoboza okuningi ukuthola imithambo
• I-hematoma (ukuqoqwa kwegazi ngaphansi kwesikhumba)
• Ukutheleleka (ingozi encane noma kunini lapho isikhumba siphukile)

Umsebenzi we-Plasma renin; I-renin ye-plasma engahleliwe; I-PRA

• Izinso - ukugeleza kwegazi nomchamo
• Ukuhlolwa kwegazi

UGuber HA, uFarag AF. Ukuhlolwa komsebenzi we-endocrine. Ku: McPherson RA, Pincus MR, abahleli. UHenry’s Clinical Diagnosis and Management by Laboratory Methods. Umhla ka-23. ISt Louis, MO: Elsevier; 2017: isahluko 24.

I-ID ye-Weiner, i-Wingo CS. Izimbangela ze-Endocrine ze-hypertension: aldosterone. Ku: Feehally J, Floege J, Tonelli M, Johnson RJ, abahleli. I-Nephrology Yomtholampilo Ephelele. Umhlaka 6. IPhiladelphia, PA: Elsevier; 2019: isahluko 38.