Ukuhlolwa kwe-insulin C-peptide

I-C-peptide yinto edalwa lapho kukhiqizwa i-hormone insulin futhi ikhishelwa emzimbeni. Ukuhlolwa kwe-insulin C-peptide kukala inani lalo mkhiqizo osegazini.

Kudingeka isampula yegazi.

Ukulungiselela isivivinyo kuya ngesizathu sesilinganiso se-C-peptide. Buza umhlinzeki wakho wezempilo ukuthi akufanele yini udle (ngokushesha) ngaphambi kokuhlolwa. Umhlinzeki wakho angakucela ukuthi uyeke ukuthatha imithi engathinta imiphumela yokuhlolwa.

Lapho inaliti ifakwa ukudonsa igazi, abanye abantu bezwa ubuhlungu obulinganiselayo. Abanye bazizwa beshaywa noma betinyelwa kuphela. Ngemuva kwalokho, kungahle kube nokushaywa okuthile noma ukulimazeka okuncane. Lokhu maduzane kuyaphela.

I-C-peptide ilinganiswa ukutshela umehluko phakathi kwe-insulin ekhiqizwa ngumzimba ne-insulin ejojowe emzimbeni.

Umuntu onesifo sikashukela sohlobo 1 noma sohlobo 2 angalinganiswa izinga lakhe le-C-peptide ukuze abone ukuthi umzimba wakhe usayikhiqiza yini i-insulin. I-C-peptide ibuye ilinganiswe uma kunoshukela ophansi wegazi ukubona ukuthi umzimba womuntu ukhiqiza i-insulin eningi kakhulu.

Ukuhlolwa futhi kuyaye kuvunyelwe ukuthi kubhekwe imishanguzo ethile engasiza umzimba ukuthi ukhiqize i-insulin ethe xaxa, efana ne-glucagon-like peptide 1 analogs (GLP-1) noma DPP IV inhibitors.

Umphumela ojwayelekile uphakathi kuka-0.5 kuya ku-2.0 nanograms ngemililitha (ng / mL), noma ngo-0.2 kuye ku-0.8 nanomoles ngelitha ngalinye (nmol / L).

Ububanzi bamanani ajwayelekile bungahluka kancane phakathi kwamalabhorethri ahlukene. Amanye amalebhu asebenzisa izilinganiso ezahlukahlukene noma avivinye amasampula ahlukile. Khuluma nomhlinzeki wakho mayelana nencazelo yemiphumela yakho ethile yokuhlolwa.

Izinga elijwayelekile le-C-peptide lincike ezingeni likashukela egazini. I-C-peptide iwuphawu lokuthi umzimba wakho ukhiqiza i-insulin. Izinga eliphansi (noma cha i-C-peptide) likhombisa ukuthi amanyikwe akho akhiqiza i-insulin encane noma akanayo nhlobo.

• Izinga eliphansi lingajwayelekile uma ungadlanga muva nje. Ushukela wegazi kanye namazinga e-insulin akho ngokwemvelo abe phansi ngaleso sikhathi.
• Izinga eliphansi alijwayelekile uma ushukela wegazi lakho uphakeme futhi umzimba wakho kufanele wenze i-insulin ngaleso sikhathi.

Abantu abanesifo sikashukela sohlobo 2, ukukhuluphala ngokweqile, noma ukumelana ne-insulin bangaba nezinga eliphezulu le-C-peptide. Lokhu kusho ukuthi umzimba wabo ukhiqiza i-insulin eningi ukugcina (noma ukuzama ukugcina) ushukela wegazi wabo ujwayelekile.

Kunobungozi obuncane obubandakanyekile ekuthatheni igazi lakho.Imithambo yegazi nemithambo yegazi iyehluka ngosayizi komunye umuntu iye kolunye uhlangothi nangolunye uhlangothi lomzimba. Ukuthola isampula yegazi kwabanye abantu kungaba nzima kakhulu ukwedlula kwabanye.

Ezinye izingozi ezihambisana nokudonswa igazi zincane kepha zingafaka:

• Ukopha
• Ukuquleka noma uzizwe unekhanda elincane
• Ukubhoboza okuningi ukuzama ukuthola imithambo
• I-hematoma (i-blood buildup ngaphansi kwesikhumba)
• Ukutheleleka (ingozi encane noma kunini lapho isikhumba siphukile)

C-peptide

• Ukuhlolwa kwegazi

I-Atkinson MA, Mcgill DE, Dassau E, Laffel L. Thayipha i-1 yesifo sikashukela. Ku: Melmed S, Auchus RJ, Goldfine AB, Koenig RJ, Rosen CJ, abahleli. Incwadi kaWilliams ye-Endocrinology. Umhlaka 14. IPhiladelphia, PA: Elsevier; 2020: isahluko 36.

IChernecky CC, iBerger BJ. C-peptide (peptide yokuxhuma) - i-serum. Ku: IChernecky CC, iBerger BJ, ama-eds. Ukuhlolwa Kwelabhoratri Nezinqubo Zokuxilonga. Umhlaka 6. IPhiladelphia, PA: Elsevier; 2013: 391-392.

I-Kahn CR, i-Ferris HA, i-O'Neill BT. I-Pathophysiology yohlobo 2 sikashukela mellitus. Ku: Melmed S, Auchus RJ, Goldfine AB, Koenig RJ, Rosen CJ, abahleli. Incwadi kaWilliams ye-Endocrinology. Umhlaka 14. IPhiladelphia, PA: Elsevier; 2020: isahluko 34.

UPearson ER, uMcCrimmon RJ. Isifo sikashukela. Ku: Ralston SH, ID Penman, Strachen MWJ, Hobson RP, eds. Izimiso zikaDavidson kanye Nokuzijwayeza Kwezokwelapha. Umhla ka-23. IPhiladelphia, PA: Elsevier; 2020: isahluko 20.