Ukuhlolwa kwegazi le-Estradiol

Ukuhlolwa kwe-estradiol kukala inani le-hormone ebizwa nge-estradiol egazini. I-Estradiol ingenye yezinhlobo eziyinhloko zama-estrogens.

Kudingeka isampula yegazi.

Umhlinzeki wakho wezokunakekelwa kwempilo angakutshela ukuthi uyeke ukuthatha imithi ethile okwesikhashana engathinta imiphumela yokuhlolwa. Qiniseka ukuthi utshela umhlinzeki wakho ngayo yonke imithi oyiphuzayo. Lokhu kufaka phakathi:

• Amaphilisi okuvimbela inzalo
• Imithi elwa namagciwane efana ne-ampicillin noma i-tetracycline
• Ama-Corticosteroids
• I-DHEA (isengezo)
• I-Estrogen
• Imithi yokuphatha ukuphazamiseka kwengqondo (njenge phenothiazine)
• I-testosterone

Ungayeki ukuthatha noma imuphi umuthi ngaphambi kokukhuluma nodokotela wakho.

Lapho inaliti ifakwa ukudonsa igazi, abanye abantu bezwa ubuhlungu obulinganiselayo. Abanye bazizwa beshaywa noma betinyelwa kuphela. Ngemuva kwalokho, kungahle kube nokushaywa okuthile noma ukulimazeka okuncane. Lokhu maduzane kuyaphela.

Kwabesifazane, iningi le-estradiol likhishwa kuma-ovari nasezindlala ze-adrenal. Iphinde ikhishwe yi-placenta ngesikhathi sokukhulelwa. I-Estradiol nayo ikhiqizwa kwezinye izicubu zomzimba, njengesikhumba, amafutha, amaseli amathambo, ubuchopho nesibindi. I-Estradiol idlala indima ku:

• Ukukhula kwesibeletho (isibeletho), amashubhu ezulu, kanye nesitho sangasese sowesifazane
• Ukukhula kwamabele
• Izinguquko zesitho sangasese sangaphandle
• Ukusatshalaliswa kwamafutha omzimba
• Ukunqamuka kokuya esikhathini

Emadodeni, inani elincane le-estradiol likhishwa ikakhulukazi ngama-testes. I-Estradiol isiza ukuvimbela isidoda ukuthi singafi kusenesikhathi.

Lokhu kuhlolwa kungayalelwa ukuthi kuhlolwe:

• Asebenza kahle kangakanani amaqanda akho, i-placenta, noma izindlala ze-adrenal
• Uma unezimpawu zesimila esibelethweni
• Uma izici zomzimba wowesilisa noma wesifazane zingakhuli ngendlela ejwayelekile
• Uma izikhathi zakho zimile (amazinga e-estradiol ayahluka, kuye ngesikhathi senyanga)

Ukuhlolwa kungabuye futhi kuyalwe ukuthi kubhekwe ukuthi:

• Ukwelashwa kweHormone kusebenza kubantu besifazane abanqamuka esikhathini
• Owesifazane uphendula ekwelashweni kokuzala

Ukuhlolwa kungasetshenziswa futhi ukuqapha abantu abane-hypopituitarism kanye nabesifazane ekwelashweni okuthile kokuzala.

Imiphumela ingahluka, kuye ngobulili nobudala bomuntu.

• Owesilisa - 10 kuya ku-50 pg / mL (36.7 kuya ku-183.6 pmol / L)
• Owesifazane (premenopausal) - 30 kuya ku-400 pg / mL (110 kuya ku-1468.4 pmol / L)
• Owesifazane (postmenopausal) - 0 kuya ku-30 ​​pg / mL (0 kuya ku-110 pmol / L)

Ububanzi bamanani ajwayelekile bungahluka kancane phakathi kwamalabhorethri ahlukene. Amanye amalebhu asebenzisa izilinganiso ezahlukahlukene noma avivinye amasampula ahlukile. Khuluma nodokotela wakho mayelana nencazelo yomphumela wakho wokuhlolwa othize.

Ukuphazamiseka okuhambisana nemiphumela engajwayelekile ye-estradiol kufaka:

• Ukuthomba kwangaphambi kwesikhathi (okungajwayelekile) emantombazaneni
• Ukukhula kwamabele amakhulu ngokungajwayelekile emadodeni (gynecomastia)
• Ukungabi nezikhathi kwabesifazane (amenorrhea)
• Umsebenzi owehlisiwe wama-ovari (i-ovarian hypofunction)
• Inkinga ngezakhi zofuzo, njenge-Klinefelter syndrome, i-Turner syndrome
• Ukulahleka kwesisindo okusheshayo noma amafutha omzimba aphansi

Kunengozi encane ethintekayo ekuthatheni igazi lakho. Imithambo nemithambo yegazi kuyahluka ngosayizi komunye umuntu kuya kolunye uhlangothi lomzimba kuya kolunye. Ukuthatha igazi kwabanye abantu kungaba nzima kakhulu ukwedlula kwabanye.

Ezinye izingozi ezihambisana nokudonswa igazi zincane, kepha zingafaka:

• Ukopha ngokweqile
• Ukuquleka noma uzizwe unekhanda elincane
• Ukubhoboza okuningi ukuthola imithambo
• I-hematoma (ukuqoqwa kwegazi ngaphansi kwesikhumba)
• Ukutheleleka (ingozi encane noma kunini lapho isikhumba siphukile)

Ukuhlolwa kwe-E2

UGuber HA, uFarag AF. Ukuhlolwa komsebenzi we-endocrine. Ku: McPherson RA, Pincus MR, abahleli. UHenry’s Clinical Diagnosis and Management by Laboratory Methods. Umhla ka-23. ISt Louis, MO: Elsevier; 2017: isahluko 24.

I-Haisenleder DJ, uMarshall JC. Ama-gonadotropin: ukulawulwa kokuhlanganiswa nokufihlwa. Ku: Jameson JL, De Groot LJ, de Kretser DM, et al, abahleli. I-Endocrinology: Eyabantu Abadala Neyengane. Umhla wesi-7. IPhiladelphia, PA: Elsevier Saunders; 2016: isahluko 116.