Umlobi: Marcus Baldwin
Usuku Lokudalwa: 18 Ujuni 2021
Ukuvuselela Usuku: 16 Unovemba 2024
Anonim
I-sepsis engakazalwa - Umuthi
I-sepsis engakazalwa - Umuthi

I-Neonatal sepsis ukutheleleka kwegazi okwenzeka enganeni engaphansi kwezinsuku ezingama-90 ubudala. I-sepsis yokuqala-ekuqaleni ibonakala esontweni lokuqala lokuphila. Isikhathi sokuqala sepsis senzeka ngemuva kweviki elilodwa kuya ezinyangeni ezintathu ubudala.

I-Neonatal sepsis ingabangelwa amagciwane afana ne- Escherichia coli (E coli), IListeria, kanye nezinye izinhlobo ze-streptococcus. I-streptococcus yeqembu B (i-GBS) ibe yimbangela enkulu ye-sepsis ebelethayo. Kodwa-ke, le nkinga seyande kakhulu ngoba abesifazane bayahlolwa ngesikhathi sokukhulelwa. Igciwane le-herpes simplex (HSV) lingadala nokutheleleka okunzima enganeni esanda kuzalwa. Lokhu kwenzeka kaningi lapho umama esanda kutheleleka.

I-sepsis esanda kuzalwa ivame ukuvela kungakapheli amahora angama-24 kuye kwangama-48 wokuzalwa. Ingane ithola ukutheleleka kunina ngaphambi noma ngesikhathi sokubeletha. Lokhu okulandelayo kwandisa ingozi yengane yokuthola i-sepsis yokuqala yebhaktheriya:

  • I-GBS colonization ngesikhathi sokukhulelwa
  • Ukulethwa kwangaphambi kwesikhathi
  • Ukwephuka kwamanzi (ukuqhekeka kolwelwesi) isikhathi eside kunamahora ayi-18 ngaphambi kokuzalwa
  • Ukutheleleka kwezicubu ze-placenta kanye ne-amniotic fluid (chorioamnionitis)

Izingane ezine-sepsis ebelethwe sekwedlule isikhathi zitheleleka ngemuva kokubeletha. Lokhu okulandelayo kwandisa ingozi yengane ye-sepsis ngemuva kokubeletha:


  • Ukuba ne-catheter esitsheni segazi isikhathi eside
  • Ukuhlala esibhedlela isikhathi eside

Izinsana ezine-sepsis ezisanda kuzalwa zingaba nalezi zimpawu ezilandelayo:

  • Izinguquko zokushisa komzimba
  • Izinkinga zokuphefumula
  • Isifo sohudo noma ukwehla kwamathumbu
  • Ushukela wegazi ophansi
  • Ukunyakaza okuncishisiwe
  • Ukwehlisa ukuncela
  • Ukuquleka
  • Ukushaya kwenhliziyo okuhamba kancane noma okusheshayo
  • Indawo yesisu evuvukile
  • Ukuhlanza
  • Isikhumba esiphuzi nabamhlophe bamehlo (i-jaundice)

Ukuhlolwa kwelebhu kungasiza ekutholeni i-sepsis ebelethayo nokuthola imbangela yokutheleleka. Ukuhlolwa kwegazi kungafaka:

  • Isiko legazi
  • Amaprotheni asebenza ngo-C
  • Qedela ukubalwa kwegazi (CBC)

Uma ingane inezimpawu ze-sepsis, kuzokwenziwa i-lumbar puncture (umpompi womgogodla) ukubheka uketshezi lomgogodla wamagciwane. Amasiko esikhumba, isitulo kanye nomchamo kungenziwa ngegciwane le-herpes, ikakhulukazi uma umama enomlando wokutheleleka.

I-x-ray yesifuba izokwenziwa uma ingane ikhwehlela noma inenkinga yokuphefumula.


Ukuhlolwa kwesiko lomchamo kwenziwa ezinganeni ezindala kunezinsuku ezimbalwa.

Izingane ezingaphansi kwamasonto amane ubudala ezinomkhuhlane noma ezinye izimpawu zokutheleleka ziqala ngemithi elwa namagciwane (IV) ngokushesha. (Kungathatha amahora angama-24 kuye kwangama-72 ukuthola imiphumela yelabhu.) Izinsana ezinomama abane-chorioamnionitis noma abangaba sengozini enkulu yezinye izizathu nabo bazothola ama-antibiotic e-IV ekuqaleni, noma bengenazo izimpawu.

Ingane izothola ama-antibiotic kuze kuphele amasonto ama-3 uma amagciwane etholakala egazini noma emanzini omgogodla. Ukwelashwa kuzoba mfushane uma kungekho magciwane atholakala.

Umuthi we-antiviral obizwa nge-acyclovir uzosetshenziselwa ukutheleleka okungabangelwa yi-HSV. Izinsana ezindala ezinemiphumela evamile yelebhu futhi ezinomkhuhlane kuphela kungenzeka zinganikezwa ama-antibiotic. Esikhundleni salokho, ingane ingakwazi ukuphuma esibhedlela ibuye iyohlolwa.

Izingane ezidinga ukwelashwa futhi esezivele sezihambile emakhaya ngemuva kokuzalwa zivame ukungeniswa esibhedlela ukuze ziqashwe.

Izingane eziningi ezinezifo ezibangelwa amagciwane zizolulama ngokuphelele futhi azinazo ezinye izinkinga. Kodwa-ke, i-neonatal sepsis iyimbangela ehamba phambili yokufa kwezinsana. Lapho usana luthola ngokushesha ukwelashwa, kuba ngcono umphumela.


Izinkinga zingafaka:

  • Ukukhubazeka
  • Ukufa

Funa usizo lwezokwelapha khona manjalo ukuthola usana olubonisa izimpawu ze-nepsatal sepsis.

Abesifazane abakhulelwe bangadinga ama-antibiotic okuvimbela uma ngabe:

  • I-Chorioamnionitis
  • Ikoloni lokusakaza kweqembu B
  • Ukunikezwa esikhathini esidlule enganeni ene-sepsis ebangelwa amagciwane

Ezinye izinto ezingasiza ukuvimbela i-sepsis zifaka:

  • Ukuvimbela nokwelapha izifo komama, kufaka phakathi i-HSV
  • Ukuhlinzeka ngendawo ehlanzekile yokuzalwa
  • Ukuletha ingane kungakapheli amahora ayi-12 kuye kwangama-24 lapho ulwelwesi luphuka (ukulethwa kukaKesari kufanele kwenziwe kwabesifazane kungakapheli amahora amane kuya kwayisithupha noma kusheshe kuphuka ulwelwesi.)

Sepsis neonatorum; I-septicemia engakazalwa; Sepsis - usana

IKomidi Lezifo Ezithathelwanayo, Ikomidi Lezisu Nezinsana; UBaker CJ, uByington CL, uPolin RA. Isitatimende senqubomgomo - izincomo zokuvimbela isifo se-perinatal group B streptococcal (GBS). Izifo zezingane. 2011; 128 (3): 611-616. I-PMID: 21807694 www.ncbi.nlm.nih.gov/pubmed/21807694.

Ukutheleleka kwamagciwane e-Esper F. Ngemuva kokubeletha. KuMartin RJ, uFanaroff AA, uWalsh MC, ama-eds. UFanaroff kanye neMithi kaMartin's Neonatal-Perinatal Medicine. Umhla ka-11. IPhiladelphia, PA: Elsevier; 2020: isahluko 48.

IGreenberg JM, uHaberman B, uNarendran V, uNathan AT, uSchibler K. Izifo ezisencane zokubeletha kwemvelaphi yokubeletha neyangaphambi kokubeletha. Ku: Resnik R, Lockwood CJ, Moore TR, Greene MF, Copel JA, Silver RM, abahleli. ICreasy neResnik's Maternal-Fetal Medicine: Izimiso kanye Nokuzijwayeza. Umhlaka 8. IPhiladelphia, PA: Elsevier; 2019: isahluko 73.

UJaganath D, uSame RG. Microbiology kanye nezifo ezithathelwanayo. Ku: Isibhedlela iJohns Hopkins; UHughes HK, Kahl LK, ama-eds. IHarriet Lane Handbook. Umhlaka 21. IPhiladelphia, PA: Elsevier; 2018: isahluko 17.

UPolin R, uRandis TM. Izifo ze-Perinatal kanye ne-chorioamnionitis. KuMartin RJ, uFanaroff AA, uWalsh MC, ama-eds. UFanaroff kanye neMithi kaMartin's Neonatal-Perinatal Medicine. Umhla ka-11. IPhiladelphia, PA: Elsevier; 2020: isahluko 25.

UVerani JR, McGee L, uSchrag SJ; Ukwahlukaniswa Kwezifo Zebacteria, Isikhungo Sikazwelonke Sokugoma Nezifo Zokuphefumula, Izikhungo Zokulawulwa Nokuvikelwa Kwezifo (CDC). Ukuvinjelwa kweqembu le-perinatal B isifo se-streptococcal - imihlahlandlela ebukeziwe evela kuCDC, 2010. Incoma i-MMWR Rep. 2010; 59 (RR-10): 1-36. I-PMID: 21088663 www.ncbi.nlm.nih.gov/pubmed/21088663.

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