Ukuhlolwa kweTroponin

Ukuhlolwa kwe-troponin kukala amazinga we-troponin T noma i-troponin I amaprotheni egazini. Lawa maprotheni akhishwa lapho imisipha yenhliziyo iye yalimala, njengokuvela kwesifo senhliziyo. Uma kunomonakalo omkhulu enhliziyweni, nenani le-troponin T nami lizoba khona egazini.

Kudingeka isampula yegazi.

Azikho izinyathelo ezikhethekile ezidingekayo ukulungiselela, isikhathi esiningi.

Ungase uzwe ubuhlungu obuncane noma isitinyela lapho kufakwa inaliti. Ungase futhi uzizwe ushaywa yisiza ngemuva kokukhishwa kwegazi.

Isizathu esivame kakhulu ukwenza lolu vivinyo ukubona ukuthi ngabe isifo senhliziyo senzekile yini. Umhlinzeki wakho wezokunakekelwa kwempilo uzoku-oda lokhu kuhlolwa uma unezinhlungu esifubeni nezinye izimpawu zokuhlaselwa yisifo senhliziyo. Ukuhlolwa kuvame ukuphindwa kabili ngaphezulu kwamahora ayisithupha kuya kwangu-24 alandelayo.

Umhlinzeki wakho angaphinde ahlele lokhu kuhlolwa uma une-angina eya ngokuya iba yimbi, kepha azikho ezinye izimpawu zokuhlaselwa yinhliziyo. (U-Angina ubuhlungu besifuba okucatshangwa ukuthi buvela engxenyeni yenhliziyo yakho engatholi ukugeleza kwegazi okwanele.)

Ukuhlolwa kwe-troponin kungenziwa futhi ukusiza ukuthola nokuhlola ezinye izimbangela zokulimala kwenhliziyo.

Ukuhlolwa kungenziwa kanye nezinye izivivinyo zomaka wenhliziyo, njenge-CPK isoenzymes noma i-myoglobin.

Amazinga we-Cardiac troponin ngokuvamile aphansi kakhulu futhi angatholakali ngokuhlolwa kwegazi okuningi.

Ukuba namazinga ajwayelekile we-troponin amahora ayi-12 ngemuva kokuqala kwesifo esifubeni kusho ukuthi ukuhlaselwa yinhliziyo akunakwenzeka.

Ibanga lenani elijwayelekile lingahluka kancane phakathi kwamalabhorethri ahlukile. Amanye amalebhu asebenzisa izilinganiso ezahlukahlukene (isibonelo, "high sensitivity troponin test") noma hlola amasampula ahlukile. Futhi, amanye amalebhu anamaphoyinti ahlukene okusika "okuvamile" kanye "ne-infarction engaba khona ye-myocardial." Khuluma nomhlinzeki wakho mayelana nencazelo yemiphumela yakho ethile yokuhlolwa.

Ngisho nokwanda okuncane kwezinga le-troponin kuzosho ukuthi kube khona ukulimala enhliziyweni. Amazinga aphezulu kakhulu we-troponin awuphawu lokuthi kuhlaselwe yisifo senhliziyo.

Iningi leziguli ezihlaselwe yisifo senhliziyo lenyuke amazinga e-troponin kungakapheli amahora ayisithupha. Ngemuva kwamahora ayi-12, cishe wonke umuntu oke wahlaselwa yisifo senhliziyo uzobe ephakamile amazinga.

Amazinga eTroponin angahlala ephezulu amasonto ayi-1 kuye kwayi-2 ngemuva kokuhlaselwa yisifo senhliziyo.

Ukukhuphuka kwamazinga e-troponin nakho kungabangelwa:

• Ukushaya kwenhliziyo okusheshayo ngokungavamile
• Umfutho wegazi ophakeme emithanjeni yamaphaphu (umfutho wegazi ophakeme wamaphaphu)
• Ukuvalwa komthambo wamaphaphu ngegazi, ngamafutha, noma ngamangqamuzana wesimila (embolus pulmonary)
• Ukwehluleka kwenhliziyo yokubopha
• Umthambo weCoronary spasm
• Ukuvuvukala kwemisipha yenhliziyo imvamisa kungenxa yegciwane (i-myocarditis)
• Ukuvivinya umzimba isikhathi eside (ngokwesibonelo, ngenxa yama-marathoni noma ama-triathlons)
• Ukuhlukumezeka okulimaza inhliziyo, njengengozi yemoto
• Ukubuthaka kwemisipha yenhliziyo (i-cardiomyopathy)
• Isifo sezinso sesikhathi eside

Ukukhuphuka kwamazinga e-troponin nakho kungavela ezinqubweni ezithile zezokwelapha ezinjenge:

• I-angioplasty yenhliziyo / ukuthukuthela
• I-defibrillation yenhliziyo noma i-cardioversion kagesi (ukwethusa okunenhliziyo kwenhliziyo ngabasebenzi bezokwelapha ukulungisa isigqi senhliziyo esingajwayelekile)
• Vula ukuhlinzwa kwenhliziyo
• Ukuchithwa kwemisebe yenhliziyo

TroponinI; TnI; I-TroponinT; TnT; I-troponin eqondene nenhliziyo I; I-troponin eqondene nenhliziyo T; cTnl; cTnT

I-Bohula EA, i-Morrow DA. I-ST-Elevation infarction ye-myocardial: ukuphathwa. Ku: Zipes DP, Libby P, Bonow RO, Mann DL, Tomaselli GF, Braunwald E, ama-eds. Isifo Senhliziyo SikaBraunwald: Incwadi Yemithi Yezinhliziyo Nemithambo. Umhla ka-11. IPhiladelphia, PA: Elsevier; 2018: isahluko 59.

Bonaca, MP, Sabatine MS. Sondela esigulini ngobuhlungu besifuba. Ku: Zipes DP, Libby P, Bonow RO, Mann DL, Tomaselli GF, Braunwald E, ama-eds. Isifo Senhliziyo SikaBraunwald: Incwadi Yemithi Yezinhliziyo Nemithambo. Umhla ka-11. IPhiladelphia, PA: Elsevier; 2019: isahluko 56.

ILevine GN, iBates ER, Blankenship JC, et al. I-2015 ACC / AHA / SCAI Ukugxila kokubuyekezwa kokungenelela okuyisisekelo kwe-coronary yeziguli ezine-ST-Elevation myocardial infarction: isibuyekezo se-2011 ACCF / AHA / SCAI umhlahlandlela wokungenelela kwe-coronary okungenzeka kanye nomhlahlandlela we-ACCF / AHA ka-2013 wokuphathwa kwe-ST- I-Elevation myocardial infarction: umbiko we-American College of Cardiology / American Heart Association Task Force ngemihlahlandlela yokusebenza komtholampilo kanye neSociety for Cardiovascular Angiography and Interventions. Ukujikeleza. 2016; 133 (11): 1135-1147. I-PMID: 26490017 www.ncbi.nlm.nih.gov/pubmed/26490017.

UThygesen K, Alpert JS, Jaffe AS, Chaitman BR, Bax JJ, Morrow DA, White HD; I-Executive Group esikhundleni seJoint European Society of Cardiology (ESC) / American College of Cardiology (ACC) / American Heart Association (AHA) / World Heart Federation (WHF) Task Force for the Universal Definition of Myocardial Infarction. Incazelo Yesine Yomhlaba Wonke Ye-Myocardial Infarction (2018). Ukujikeleza. I-2018; 138 (20): e618-e651 PMID: 30571511 www.ncbi.nlm.nih.gov/pubmed/30571511.