Izidakamizwa ze-thrombolytic zokuhlaselwa yisifo senhliziyo

Imithambo yegazi emincane ebizwa ngemithambo yegazi ihambisa umoya-mpilo othwala igazi liye emisipheni yenhliziyo.

• Ukuhlaselwa yinhliziyo kungenzeka uma ihlule legazi limisa ukuhamba kwegazi ngomunye wale mithambo.
• I-angina engazinzile ibhekisa ebuhlungwini besifuba nezinye izimpawu zokuxwayisa ukuthi isifo senhliziyo singenzeka kungekudala. Ngokuvamile kubangelwa amahlule egazi emithanjeni yegazi.

Abanye abantu banganikezwa izidakamizwa zokuqeda ihlwili uma umthambo uvinjwe ngokuphelele.

• Le mithi ibizwa nge-thrombolytics, noma imishanguzo yokuvala amahlule.
• Zinikezwa kuphela uhlobo lokuhlaselwa yisifo senhliziyo, lapho izinguquko ezithile ziphawulwa ku-ECG. Lolu hlobo lokuhlaselwa yinhliziyo lubizwa nge-ST segment elevation myocardial infarction (STEMI).
• Le mithi kufanele inikezwe ngokushesha okukhulu ngemuva kokuvela kobuhlungu besifuba (imvamisa kakhulu ngaphansi kwamahora ayi-12).
• Umuthi unikezwa ngomthambo (IV).
• Abanciphisi begazi abathathwe ngomlomo bangabekwa kamuva ukuvimbela amahlule amaningi ukuthi angakhi.

Ingcuphe enkulu lapho uthola imishanguzo yokopha ukuphuma kwegazi, okuhamba kakhulu ebuchosheni.

Ukwelashwa kwe-thrombolytic akuphephile kubantu abane:

• Ukopha ngaphakathi kwekhanda noma isifo sohlangothi
• Ukungajwayelekile kobuchopho, okufana nezicubu noma imithambo yegazi engakheki kahle
• Ngaba nokulimala ekhanda ezinyangeni ezi-3 ezedlule
• Umlando wokusebenzisa izinciphisi zegazi noma ukuphazamiseka kokopha
• Ngaba nokuhlinzwa okukhulu, ukulimala okukhulu, noma ukopha ngaphakathi ngaphakathi kwamasonto amathathu kuya kwamane edlule
• Isifo sesilonda se-Peptic
• Umfutho wegazi ophezulu

Okunye ukwelashwa ukuvula imikhumbi evinjiwe noma encishisiwe engenziwa endaweni noma ngemuva kokwelashwa nge-thrombolytic therapy ifaka:

• I-Angioplasty
• Ukuhlinzwa kokudlula kwenhliziyo

I-infarction ye-myocardial - i-thrombolytic; I-MI - i-thrombolytic; ST - ukuphakama kwe-infarction ye-myocardial; CAD - thrombolytic; Isifo semithambo yegazi - i-thrombolytic; STEMI - thrombolytic

I-Amsterdam EA, uWenger NK, uBrindis RG, et al. Umhlahlandlela we-2014 AHA / ACC wokuphathwa kweziguli ezine-non-ST-elevation acute coronary syndromes: umbiko we-American College of Cardiology / American Heart Association Task Force ngemihlahlandlela yokusebenza. UJ Am Coll Cardiol. 2014; 64 (24): e139-e228. I-PMID: 25260718 www.ncbi.nlm.nih.gov/pubmed/25260718.

I-Bohula EA, i-Morrow DA. I-ST-elevation infarction ye-myocardial: ukuphathwa. Ku: Zipes DP, Libby P, Bonow RO, Mann DL, Tomaselli GF, Braunwald E, ama-eds. Isifo Senhliziyo SikaBraunwald: Incwadi Yemithi Yezinhliziyo Nemithambo. Umhla ka-11. IPhiladelphia, PA: Elsevier; 2019: isahluko 59.

U-Ibanez B, uJames S, u-Agewall S, et al. Imihlahlandlela ye-2017 ESC yokuphathwa kwe-infarction ye-myocardial ebukhali ezigulini ezethula ukuphakama kwesigaba se-ST: I-Task Force yokuphathwa kwe-infarction ye-myocardial ebukhali ezigulini ezethula ukuphakama kwengxenye ye-ST ye-European Society of Cardiology (ESC). Inhliziyo ye-Eur J. 2018; 39 (2): 119-177. PMID: 28886621 www.ncbi.nlm.nih.gov/pubmed/28886621.