I-eosinophilic esophagitis

I-eosinophilic esophagitis ibandakanya ukwakheka kwamangqamuzana amhlophe egazi, abizwa ngama-eosinophil, kulwelwesi lwesisu sakho. I-esophagus yishubhu elithwala ukudla kusuka emlonyeni wakho kuya esiswini sakho. Ukwakhiwa kwamaseli amhlophe egazi kungenxa yokusabela kokudla, ama-allergen, noma i-acid reflux.

Imbangela ngqo ye-eosinophilic esophagitis ayaziwa. Kukholakala ukuthi ukusabela komzimba ekudla okuthile kuholela ekwakhiweni kwama-eosinophil. Ngenxa yalokhu, ulwelwesi lwe-esophagus luyavuvukala futhi luvuvuke.

Iningi labantu abanalesi sifo linomndeni noma umlando womuntu siqu we-allergies noma i-asthma. Izimbangela ezinjengesikhunta, impova, nezibungu zothuli nazo zingadlala indima.

I-eosinophilic esophagitis ingathinta kokubili izingane kanye nabantu abadala.

Izimpawu ezinganeni zifaka:

• Izinkinga ukondla noma ukudla
• Ubuhlungu besisu
• Ukuhlanza
• Izinkinga ukugwinya
• Ukudla kuyabambeka emphinjeni
• Ukuzuza kwesisindo esingesihle noma ukwehla kwesisindo, ukukhula okungekuhle, kanye nokungondleki

Izimpawu kubantu abadala zifaka:

• Ukudla kubambeka lapho kugwinya (i-dysphagia)
• Ubuhlungu besifuba
• Isilungulela
• Ubuhlungu besisu phezulu
• Ukubuyela emuva kokudla okungadliwe (ukuphinda usebenze kabusha)
• I-Reflux engabi ngcono ngemithi

Umhlinzeki wakho wokunakekelwa kwezempilo uzothatha umlando oningiliziwe futhi enze ukuhlolwa komzimba. Lokhu kwenzelwa ukuhlola ukungezwani kokudla nokulawula ezinye izimo, njengesifo se-reflux se-gastroesophageal (GERD).

Ukuhlolwa okungenziwa kufaka phakathi:

• Ukuhlolwa kwegazi
• Ukungezwani komzimba nokuhlolwa kwesikhumba
• I-endoscopy ephezulu
• I-biopsy of the lining of the esophagus

Alukho ikhambi futhi alukho ukwelashwa okuqondile kwe-eosinophilic esophagitis. Ukwelashwa kubandakanya ukuphatha indlela odla ngayo nokuphuza imithi.

Uma uhlola ukuthi une-aleji yokudla, ungatshelwa ukuthi ukugweme lokho kudla. Noma ungakugwema konke ukudla okwaziwayo ukuthi kungadala le nkinga. Ukudla okuvamile okufanele kugwenywe kufaka phakathi ukudla kwasolwandle, amaqanda, amantongomane, isoya, ukolweni nobisi. Ukuhlolwa kokungezwani komzimba kungathola ukudla okuthile okufanele kukugweme.

I-Proton pump inhibitors ingasiza ekulawuleni izimpawu, kodwa ayisizi inkinga ebangela izimpawu.

Umhlinzeki wakho angahle anikeze ama-topical steroids athathwe ngomlomo noma ahogelwe. Ungathatha futhi i-steroids yomlomo isikhashana. I-topical steroids ayinayo imiphumela emibi efanayo ne-oral steroids.

Uma uthuthukisa ukunciphisa noma ukuqina, inqubo yokuvula noma yokuhlanza indawo ingadingeka.

Wena nomhlinzeki wakho nizosebenza ndawonye ukuthola uhlelo lokwelashwa olusebenza kahle kakhulu kuwe.

Amaqembu okusekela afana ne-American Partnership for Eosinophilic Disorders angakusiza uqonde kabanzi nge-eosinophilic esophagitis. Ungafunda futhi izindlela zokuphatha isimo sakho nokubhekana nalesi sifo.

I-Eosinophilic esophagitis yisifo sesikhathi eside (esingapheli) esiza futhi sidlule isikhathi sokuphila komuntu.

Izinkinga ezingenzeka zingafaka:

• Ukunciphisa kwesifo (ukuqina)
• Ukudla kuyabambeka emphinjeni (okuvamile kuzingane nakubantu abadala)
• Ukuvuvukala okukhulu nokucasulwa komphimbo

Xhumana nomhlinzeki wakho uma unezimpawu ze-eosinophilic esophagitis.

• Isisu
• Ukuhlolwa kwesikhumba somzimba okweqile noma ukuhlolwa kokuqala
• Ukusabela kokuhlolwa kokungezwani komzimba kwangaphakathi

UChen JW, uKao JY. I-eosinophilic esophagitis: ukubuyekeza ekuphathweni nasezingxabanweni. BMJ. 2017; 359: j4482. I-PMID: 29133286 pubmed.ncbi.nlm.nih.gov/29133286/.

I-Falk GW, i-Katzka DA. Izifo zomphimbo. Ku: IGoldman L, iSchafer AI, ama-eds. Imithi yeGoldman-Cecil. Umhla ka-26. IPhiladelphia, PA: Elsevier; 2020: isahluko 129.

UGroetch M, uVenter C, uSkypala I, et al; IKomidi Lokukhubazeka Kwamathumbu Eosinophilic of the American Academy of Allergy, Asthma and Immunology. Ukwelashwa kokudla nokuphathwa kokudla okunomsoco we-eosinophilic esophagitis: umbiko weqembu lomsebenzi we-American Academy of Allergy, Asthma, kanye ne-Immunology. J Ukungezwani komzimba ne-Immunol Pract. 2017; 5 (2): 312-324.e29. I-PMID: 28283156 pubmed.ncbi.nlm.nih.gov/28283156/.

UKhan S. Eosinophilic esophagitis, iphilisi lokuqola, kanye ne-esophagitis yokutheleleka. Ku: Kliegman RM, St Geme JW, Blum NJ, Shah SS, Tasker RC, Wilson KM, eds. Incwadi kaNelson Yezingane. Umhlaka 21. IPhiladelphia, PA: Elsevier; 2020: isahluko 350.