Umlobi: Gregory Harris
Usuku Lokudalwa: 10 Epreli 2021
Ukuvuselela Usuku: 1 Ujuni 2024
Anonim
L-Триптофан и 5-HTP что это? Как принимать от депрессии, бессонницы и для похудения?
Ividiyo: L-Триптофан и 5-HTP что это? Как принимать от депрессии, бессонницы и для похудения?

-Delile

I-5-HTP (5-hydroxytryptophan) ingumkhiqizo wamakhemikhali owakhiwe ngebhulokhi L-tryptophan. Iphinde ikhiqizwe ngokuhweba kusuka enzalweni yesitshalo sase-Afrika esaziwa ngeGriffonia simplicifolia.

I-5-HTP isetshenziselwa ukuphazamiseka kokulala njengokuqwasha, ukucindezeleka, ukukhathazeka nezinye izimo eziningi, kodwa abukho ubufakazi obuhle besayensi obusekela iningi lalokhu kusetshenziswa.

Imibhalo Yemvelo Yemininingwane Ephelele ukukala ukusebenza ngokuncike ebufakazini besayensi ngokwesilinganiso esilandelayo: Okusebenzayo, Okungenzeka Kusebenze, Okungenzeka Kusebenze, Okungenzeka Kungasebenzi, Cishe Okungaphumeleli, Ukungasebenzi, Nobufakazi Obunganele Bokulinganisa.

Izilinganiso zokusebenza ze 5-HTP zimi kanje:

Kungenzeka kusebenze ...

  • Ukucindezeleka. Ukuthatha i-5-HTP ngomlomo kubonakala kuthuthukisa izimpawu zokucindezeleka kwabanye abantu. Olunye ucwaningo lomtholampilo lukhombisa ukuthi ukuthatha i-5-HTP ngomlomo kungahle kuzuzise njengemithi ethile elwa nodokotela yokuthuthukisa izimpawu zokucindezeleka. Ezifundweni eziningi, kwathathwa i-150-800 mg nsuku zonke ye-5-HTP. Kwezinye izimo, amanani aphezulu asetshenzisiwe.

Kungenzeka kungasebenzi ku ...

  • I-Down syndrome. Olunye ucwaningo lubonisa ukuthi ukunikeza i-5-HTP ezinganeni ezine-Down syndrome kungathuthukisa imisipha nomsebenzi. Olunye ucwaningo lukhombisa ukuthi ayithuthukisi imisipha noma ukukhula lapho ithathwa kusukela ebuntwaneni kuze kube yiminyaka engu-3-4. Ucwaningo lukhombisa nokuthi ukuthatha i-5-HTP kanye nemithi ejwayelekile kadokotela kuthuthukisa intuthuko, amakhono ezenhlalo, noma amakhono olimi.

Ubufakazi obanele bokukala ukusebenza kwe ...

  • Uhlobo lokukhathazeka olumakwe yimicabango ephindaphindwayo nokuziphatha okuphindaphindwayo (ukukhathazeka ngokweqile noma i-OCD). Ucwaningo lokuqala lubonisa ukuthi ukuthatha i-5-HTP ne-antidepressant drug fluoxetine (Prozac) amasonto ayi-12 kungathuthukisa ezinye izimpawu ze-OCD.
  • Ukuphazamiseka kokusebenzisa utshwala. Ucwaningo lwakuqala lukhombisa ukuthi ukuthatha i-5-HTP nge-D-phenylalanine ne-L-glutamine izinsuku ezingama-40 kunganciphisa izimpawu zokuhoxa utshwala. Kodwa-ke, ukuthatha i-5-HTP nge-carbidopa nsuku zonke unyaka owodwa akubonakali kusiza abantu bayeke ukuphuza. Umphumela we-5-HTP kuphela ekuphuzeni ngokweqile awucaci.
  • Isifo i-Alzheimer. Ucwaningo lwakuqala luphakamisa ukuthi ukuthatha i-5-HTP ngomlomo akusizi izimpawu zesifo i-Alzheimer.
  • Ukukhathazeka. Ubufakazi ngemiphumela ye-5-HTP yokukhathazeka abucaci. Ucwaningo lwakuqala lukhombisa ukuthi ukuthatha i-25-150 mg ye-5-HTP ngomlomo nsuku zonke kanye ne-carbidopa kubonakala kunciphisa izimpawu zokukhathazeka kubantu abanezinkinga zokukhathazeka. Kodwa-ke, olunye ucwaningo lwakuqala lukhombisa ukuthi ukuthatha imithamo ephezulu ye-5-HTP, 225 mg nsuku zonke noma ngaphezulu, kubonakala kwenza ukukhathazeka kube kubi kakhulu. Futhi, ukuthatha ama-60 mg we-5-HTP nsuku zonke ngomthambo akukunciphisi ukukhathazeka kubantu abanezinkinga zokwethuka.
  • Ukulimala kobuchopho okuthinta ukunyakaza kwemisipha (i-cerebellar ataxia). Ubufakazi bokusetshenziswa kwe-5-HTP ye-cerebellar ataxia abucaci. Ubufakazi bokuqala bukhombisa ukuthi ukuthatha u-5 mg / kg we-5-HTP nsuku zonke izinyanga ze-4 kunganciphisa ukungasebenzi kwesistimu yezinzwa. Kodwa-ke, olunye ucwaningo lukhombisa ukuthi ukuthatha i-5-HTP nsuku zonke kuze kube unyaka owodwa akuzithuthukisi izimpawu ze-cerebellar ataxia.
  • I-Fibromyalgia. Ucwaningo lwakuqala luphakamisa ukuthi ukuthatha i-100 mg ye-5-HTP ngomlomo kathathu nsuku zonke izinsuku ezingama-30-90 kungathuthukisa ubuhlungu, ubumnene, ukulala, ukukhathazeka, ukukhathala, nokuqina kwasekuseni kubantu abane-fibromyalgia.
  • Izimpawu zokunqamuka kokuya esikhathini. Ucwaningo lokuqala lubonisa ukuthi ukuthatha i-150 mg ye-5-HTP nsuku zonke amasonto ama-4 akukunciphisi ukukhanya okushisayo kwabesifazane be-postmenopausal.
  • Migraine. Ubufakazi bemiphumela ye-5-HTP yokuvikela noma yokwelapha i-migraines kubantu abadala abucaci. Olunye ucwaningo lukhombisa ukuthi ukuthatha i-5-HTP nsuku zonke akukunciphisi i-migraines, kanti ezinye izifundo zikhombisa ukuthi kungazuzisa njengemithi kadokotela. I-5-HTP ayibonakali inciphisa imigraines ezinganeni.
  • Ukukhuluphala ngokweqile. Ucwaningo lwakuqala luphakamisa ukuthi ukuthatha i-5-HTP kungasiza ekunciphiseni ukudla, ukudla okunekhalori, kanye nesisindo kubantu abakhuluphele ngokweqile. Olunye ucwaningo luphakamisa ukuthi ukusebenzisa isifutho somlomo esithile esiqukethe i-5-HTP nezinye izinto ezikhishwayo (i-5-HTP-Nat Exts, iMedestea Biotech S.p.a., iTorino, e-Italy) amasonto ama-4 kwandisa ukwehla kwesisindo cishe ngama-41% kwabesifazane abakhuluphele ngokweqile be-postmenopausal.
  • Ukuhoxa kwi-heroin, morphine, nezinye izidakamizwa ze-opioid. Ucwaningo lwasekuqaleni luphakamisa ukuthi ukuthatha ama-200 mg we-5-HTP nsuku zonke izinsuku ezingama-6 kanye ne-tyrosine, i-phosphatidylcholine, ne-L-glutamine, kungahle kunciphise ukuqwasha nezimpawu zokuhoxa ekutholeni imilutha ye-heroin.
  • Isifo se-Parkinson. Ucwaningo lwakuqala lukhombisa ukuthi ukuthatha i-100-150 mg ye-5-HTP ngomlomo nsuku zonke ngemithi ejwayelekile kubonakala kunciphisa ukuzamazama, kepha lezi zinzuzo ziqhubeka kuphela izinyanga ezifika kwezingu-5. Olunye ucwaningo lokuqala lukhombisa ukuthi ukuthatha ama-50 mg we-5-HTP nsuku zonke kunganciphisa izimpawu zokuphazamiseka kokunyakaza kusuka ku-levodopa yezidakamizwa, kanye nezimpawu zokucindezeleka, kubantu abanesifo i-Parkinson. Kepha ukuthatha imithamo emikhulu ye-5-HTP, 275-1500 mg nsuku zonke, kanye ne-carbidopa kungazenza zibe zimbi izimpawu ezithile.
  • Ikhanda lokucindezeleka. Ucwaningo lwakuqala luphakamisa ukuthi ukuthatha i-100 mg ye-5-HTP kathathu nsuku zonke emavikini ayisishiyagalombili akubunciphisi ubuhlungu noma ubude bezinhlungu zekhanda.
  • Ukunakwa kokushoda-i-hyperactivity disorder (ADHD).
  • Ukuqwasha.
  • Isifo se-premenstrual dysphoric (PMDD).
  • I-Premenstrual syndrome (i-PMS).
  • Isifo se-Ramsey-Hunt.
  • Ezinye izimo.
Kudingeka ubufakazi obuningi ukukala ukusebenza kwe-5-HTP yalokhu kusetshenziswa.

I-5-HTP isebenza ebuchosheni nasesimisweni sezinzwa eziphakathi ngokwandisa ukukhiqizwa kwe-serotonin yamakhemikhali. I-Serotonin ingathinta ukulala, isifiso sokudla, izinga lokushisa, ukuziphatha ngokocansi nokuzwa ubuhlungu. Njengoba i-5-HTP inyusa ukuhlanganiswa kwe-serotonin, isetshenziselwa izifo eziningana lapho i-serotonin ikholelwa ukuthi idlala indima ebalulekile kubandakanya ukucindezeleka, ukuqwasha, ukukhuluphala, nezinye izimo eziningi.

Lapho ithathwa ngomlomo: 5-HTP kuyinto OKUNGENZEKA UKUPHEPHA lapho uthatha ngomlomo ngokufanele. Isetshenziswe ngokuphepha ngemithamo efinyelela ku-400 mg nsuku zonke kuze kube unyaka owodwa. Kodwa abanye abantu abathathe i-5-HTP bahlakulele isimo esibizwa nge-eosinophilia-myalgia syndrome (EMS). I-EMS yisimo esibi kakhulu esifaka ubuthakathaka obukhulu bemisipha (myalgia) nokungajwayelekile kwegazi (i-eosinophilia). Abanye abantu bacabanga ukuthi i-EMS ingahle idalwe isithako sengozi noma ukungcola kweminye imikhiqizo ye-5-HTP. Kodwa abukho ubufakazi obanele besayensi ukwazi ukuthi i-EMS ibangelwa yi-5-HTP, ukungcola, noma esinye isici. Kuze kube kwaziwa okuningi, i-5-HTP kufanele isetshenziswe ngokuqapha.

Eminye imiphumela emibi engaba khona ye-5-HTP ifaka isilungulela, ubuhlungu besisu, isicanucanu, ukuhlanza, isifo sohudo, ukozela, izinkinga zocansi nezinkinga zemisipha.

5-HTP kuyinto MHLAWUMBI ANGIPHEPHILE lapho ithathwa ngomlomo ngemithamo emikhulu. Imithamo evela ku-6-10 amagremu nsuku zonke ixhunyaniswe nezinkinga ezinzima zesisu kanye nokuqaqamba kwemisipha.

Ukuqapha okukhethekile nezixwayiso:

Ukukhulelwa nokuncelisa ibele: Alukho ulwazi olwanele olunokwethenjelwa ukwazi ukuthi i-5-HTP iphephile yini ukusetshenziswa lapho ukhulelwe noma uncelisa ibele. Hlala ohlangothini oluphephile futhi ugweme ukusetshenziswa.

Izingane: 5-HTP kuyinto OKUNGENZEKA UKUPHEPHA lapho ithathwa ngomlomo ngokufanele. Imithamo efinyelela ku-5 mg / kg nsuku zonke isetshenziswe ngokuphepha kuze kube yiminyaka emi-3 ezinganeni nasezinganeni ezineminyaka engama-12 ubudala. Njengabantu abadala, kukhona nokukhathazeka mayelana namandla e-eosinophilia-myalgia syndrome (EMS) ezinganeni, isimo esibi esibandakanya ubuthakathaka obukhulu bemisipha (myalgia) kanye nokungajwayelekile kwegazi (i-eosinophilia).

Ukuhlinzwa: I-5-HTP ingathinta ikhemikhali yobuchopho ebizwa nge-serotonin. Eminye imishanguzo enikezwa ngesikhathi sokuhlinzwa ingathinta ne-serotonin. Ukuthatha i-5-HTP ngaphambi kokuhlinzwa kungadala i-serotonin eningi ebuchosheni futhi kungaholela emiphumeleni emibi ebandakanya izinkinga zenhliziyo, ukuqhaqhazela nokukhathazeka. Tshela iziguli ukuthi ziyeke ukuthatha i-5-HTP okungenani amasonto ama-2 ngaphambi kokuhlinzwa.

Okukhulu
Ungathathi le nhlanganisela.
Imithi yokudangala (MAOIs)
I-5-HTP inyusa ikhemikhali ebuchosheni ebizwa nge-serotonin. Eminye imishanguzo esetshenziselwa ukucindezelwa nayo inyusa i-serotonin. Ukuthatha i-5-HTP ngale mithi esetshenziselwa ukudangala kungakhuphula i-serotonin kakhulu. Lokhu kungadala imiphumela emibi kakhulu kubandakanya ikhanda elibuhlungu, izinkinga zenhliziyo, ukuqhaqhazela, ukudideka nokukhathazeka.

Eminye yale mithi esetshenziselwa ukucindezeleka ifaka phakathi i-phenelzine (Nardil), i-tranylcypromine (i-Parnate), neminye.
Maphakathi
Qaphela ngale nhlanganisela.
I-Carbidopa (Lodosyn)
I-5-HTP ingathinta ubuchopho. ICarbidopa (Lodosyn) nayo ingathinta ubuchopho. Ukuthatha i-5-HTP kanye ne-carbidopa kungakhuphula ubungozi bemiphumela emibi kakhulu kubandakanya inkulumo esheshayo, ukukhathazeka, ulaka nabanye.
Imithi yokudambisa (i-CNS depressants)
I-5-HTP ingadala ubuthongo nozela. Imithi ebanga ubuthongo ibizwa ngokuthi yimithi yokuthambisa. Ukuthatha i-5-HTP kanye nemithi yokwelapha kungadala ukulala kakhulu.

Eminye imishanguzo yokuthambisa ibandakanya i-clonazepam (iKlonopin), i-lorazepam (Ativan), i-phenobarbital (iDonnatal), i-zolpidem (i-Ambien), neminye.
Izidakamizwa zeSerotonergic
I-5-HTP ingakhuphula ikhemikhali ebuchosheni ebizwa nge-serotonin. Eminye imithi ibuye inyuse i-serotonin. Ukuthatha i-5-HTP kanye nale mithi kungakhuphula i-serotonin kakhulu. Lokhu kungadala imiphumela emibi kakhulu kubandakanya ikhanda elibuhlungu, izinkinga zenhliziyo, ukuqhaqhazela, ukudideka nokukhathazeka.

Eminye yale mithi ifaka i-fluoxetine (Prozac), i-paroxetine (i-Paxil), i-sertraline (i-Zoloft), i-amitriptyline (i-Elavil), i-clomipramine (i-Anafranil), i-imipramine (i-Tofranil), i-sumatriptan (Imitrex), i-zolmitriptan (i-Zomig), i-rizatriptan i-methadone (i-Dolophine), i-tramadol (i-Ultram), nezinye eziningi.
Amakhambi kanye nezithasiselo ezinezakhiwo zokuthambisa
I-5-HTP ingadala ukulala noma ukozela. Ukuyisebenzisa kanye namanye amakhambi nezithako ezinomphumela ofanayo kungadala ukulala okuningi. Amanye alawa makhambi nezithasiselo afaka i-calamus, i-poppy yaseCalifornia, i-catnip, i-hops, i-dogwood yaseJamaican, i-kava, iSt John's wort, i-skullcap, i-valerian, i-yerba mansa, nezinye.
Amakhambi nezengezo ezinezakhiwo ze-serotonergic
I-5-HTP inyusa ikhemikhali yobuchopho ebizwa nge-serotonin. Ukuthatha i-5-HTP kanye namanye amakhambi nezengezo ezandisa i-serotonin kungaholela kwi-serotonin eningi kakhulu futhi kudale imiphumela emibi kubandakanya izinkinga zenhliziyo, ukuqhaqhazela nokukhathazeka. Amanye amakhambi nezithako ezengeza amazinga e-serotonin afaka phakathi i-Hawaiian baby woodrose, i-L-tryptophan, i-S-adenosylmethionine (i-SAMe), ne-St.
Akukho ukuxhumana okwaziwayo nokudla.
Imithamo elandelayo ifundwe ocwaningweni lwesayensi: ABADALA

NGOMLOMO:
  • Yokudangala: Ngokuvamile, i-150-800 mg nsuku zonke ithathwa amasonto ama-2-6. Le mithamo kwesinye isikhathi ihlukaniswa futhi iphathwe njenge-50 mg iye ku-100 mg kathathu ngosuku. Kwesinye isikhathi umthamo uqala uphansi futhi ukhuphuke ngokuqinile njalo emavikini e-1-2 kuze kufinyelelwe umthamo ohlosiwe. Ngaphansi kokujwayelekile, kusetshenziswa imithamo ephezulu. Kwesinye isifundo, umthamo ukhuphuke ngokuqinile kuze kufike kumagremu ama-3 ngosuku.
2-Amino-3- (5-Hydroxy-1H-Indol-3-yl) Propanoic Acid, 5 Hydroxy-Tryptophan, 5 Hydroxy-Tryptophane, 5-Hydroxytryptophan, 5-Hydroxytryptophane, 5-Hydroxy L-Tryptophan, 5-Hydroxy L-Tryptophane, 5-Hydroxy Tryptophan, 5-L-Hydroxytryptophan, L-5 HTP, L-5-Hydroxytryptophan, L-5-Hydroxytryptophane, i-Oxitriptan.

Ukuze ufunde kabanzi ngokuthi le ndatshana ibhalwe kanjani, sicela ubheke ifayela le- Imibhalo Yemvelo Yemininingwane Ephelele indlela.


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