Delavirdine
-Delile
- Ngaphambi kokuthatha i-delavirdine,
- I-Delavirdine ingadala imiphumela emibi. Tshela udokotela wakho uma kukhona kulezi zimpawu ezinzima noma ezingapheli:
- Eminye imiphumela emibi ingaba mibi. Uma uhlangabezana nalezi zimpawu ezilandelayo, yeka ukuthatha i-delavirdine bese ushayela udokotela wakho ngokushesha noma uthole ukwelashwa okuphuthumayo:
IDelavirdine ayisatholakali e-United States.
I-Delavirdine isetshenziswa kanye neminye imithi yokwelapha ukutheleleka ngegciwane lesandulela ngculaza (i-HIV). IDelavirdine isekilasini lemithi ebizwa nge-non-nucleoside reverse transcriptase inhibitors (NNRTIs). Isebenza ngokunciphisa inani le-HIV egazini. Yize i-delavirdine ingayelaphi i-HIV, ingahle inciphise amathuba okuba ne-immunodeficiency syndrome (i-AIDS) kanye nezifo ezihlobene ne-HIV ezinjengezifo ezibucayi noma umdlavuza. Ukuthatha le mithi kanye nokwenza ucansi oluphephile nokwenza ezinye izinguquko endleleni yokuphila kunganciphisa ubungozi bokudlulisela (ukusabalalisa) igciwane le-HIV kwabanye abantu.
I-Delavirdine iza njengethebhulethi ezothathwa ngomlomo. Imvamisa kuthathwa kathathu ngosuku noma ngaphandle kokudla. Thatha i-delavirdine ngasikhathi sinye nsuku zonke. Landela izinkomba ezikulebuli kadokotela wakho ngokucophelela, bese ubuza udokotela noma usokhemisi wakho ukuthi akuchaze nganoma iyiphi ingxenye ongayiqondi. Thatha i-delavirdine njengoba nje kuqondisiwe. Ungayithathi kancane noma uyithathe kaningi kunokuyalelwa ngudokotela wakho.
Uma unenkinga yokugwinya amaphilisi ayi-100-mg, angahlakazeka emanzini. Ukuzilungiselela, engeza amaphilisi amane okungenani ama-ounces amathathu (90 milliliters) wamanzi, vumela ukuma imizuzu embalwa, bese unyakazisa aze ancibilike wonke amaphilisi. Phuza ingxube yamanzi e-delavirdine ngokushesha. Hlanza ingilazi bese ugwinya ukugeza ukuze uqinisekise ukuthi usutholile wonke umthamo. Amathebulethi angama-200-mg (amancane kunama-100-mg tablet) kufanele agwinywe ephelele, ngoba awancibiliki kalula emanzini.
Udokotela wakho angakutshela ukuthi uthathe amaphilisi e-delavirdine ngejusi le-orange noma le-cranberry uma unezimo ezithile zezokwelapha ezifana ne-achlorhydria (isimo lapho isisu singenayo i-asidi encane). Landela lezi zinkomba ngokucophelela.
IDelavirdine ingayilawula i-HIV kepha ngeke iyelaphe. Qhubeka uthathe i-delavirdine noma ngabe uzizwa uphilile. Ungayeki ukuphuza i-delavirdine noma omunye umuthi owuthathayo ukwelapha i-HIV noma i-AIDS ngaphandle kokukhuluma nodokotela wakho. Lapho ukunikezwa kwakho kwe-delavirdine kuqala ukwehla, thola okuningi kudokotela noma kukhemisi wakho. Uma uphuthelwa amanani noma uyeka ukuthatha i-delavirdine, isimo sakho singaba nzima ukwelapha.
Buza usokhemisi noma udokotela wakho ikhophi lemininingwane yomkhiqizi yesiguli.
Lo muthi kwesinye isikhathi ubekelwa okunye ukusetshenziswa; buza udokotela wakho noma usokhemisi ukuthola eminye imininingwane.
Ngaphambi kokuthatha i-delavirdine,
- Tshela udokotela wakho kanye nosokhemisi uma une-aleji ku-delavirdine, noma imiphi eminye imithi, noma iziphi izithako ezikumaphilisi e-delavirdine. Buza usokhemisi wakho ukuthola uhlu lwezithako.
- utshele udokotela wakho uma uthatha i-alprazolam (Xanax); ama-antihistamine athile afana ne-astemizole (Hismanal) (awasatholakali e-U.S.) ne-terfenadine (Seldane) (ayisatholakali e-U.S.); imithi ethile yohlobo lwe-ergot efana ne-dihydroergotamine (i-DHE 45, i-Migranal), i-ergonovine (i-Ergotrate), i-ergotamine tartrate (i-Ergomar, eCafergot, eMigergot), ne-methylergonovine (Methergine); i-cisapride (Propulsid) (ayisatholakali e-U.S.); i-midazolam (iVesi); ipimozide (i-Orap); kanye ne-triazolam (Halcion). Udokotela wakho mhlawumbe uzokutshela ukuthi ungathathi i-delavirdine uma uthatha eyodwa noma ngaphezulu yale mithi.
- Tshela udokotela wakho kanye nosokhemisi ukuthi imiphi imishanguzo kadokotela noma engabhaliswanga, amavithamini, kanye nezithako zokudla okunomsoco ozithathayo noma ohlela ukuzithatha. Qiniseka ukuthi usho noma yikuphi okulandelayo: ama-amphetamine afana ne-amphetamine (Adderall) ne-dextroamphetamine (Dexadrine, Dextrostat); ama-anticoagulants (’ama-thinner egazi’) afana ne-warfarin (Coumadin); ama-calcium channel blocker afana ne-amlodipine (Norvasc), diltiazem (Cardizem, Dilacor, Tiazac), felodipine (Plendil), isradipine (DynaCirc), nicardipine (Cardene), nifedipine (Adalat, Procardia), nimodipine (Nimotop), nisoldipine , kanye ne-verapamil (Calan, Covera, Isoptin, Verelan); imithi ethile yokwelapha i-cholesterol ephezulu njenge-atorvastatin (Lipitor), i-cerivastatin (i-Baycol), i-fluvastatin (i-Lescol), i-lovastatin (i-Mevacor), ne-simvastatin (i-Zocor); imithi ethile yokwelapha ukuquleka okufana ne-carbamazepine (Tegretol, Carbatrol), phenobarbital, ne-phenytoin (Dilantin, Phenytek); i-clarithromycin (i-Biaxin); i-cyclosporine (iNeoral, iSandimmune); i-dexamethasone (i-Decadron); i-fluticasone (i-Flonase, i-Flovent, i-Veramyst); imishanguzo yokushaya kwenhliziyo okungajwayelekile njenge-amiodarone (Cordarone), i-bepridil (i-Bepadin) (ayisatholakali e-U.S.), i-lidocaine, i-quinidine, i-flecainide (i-Tambocor) ne-propafenone (i-Rythmol); imithi ye-indigestion, isilungulela, noma izilonda ezifana ne-cimetidine (Tagamet), i-famotidine (i-Pepcid), i-lansoprazole (i-Prevacid), i-nizatidine (i-Axid), i-omeprazole (i-Prilosec), ne-ranitidine (i-Zantac); i-methadone (i-Dolophine, i-Methadose); izinto zokuvimbela inzalo ngomlomo (amaphilisi okuvimbela inzalo); eminye imithi yokwelapha i-HIV kubandakanya i-didanosine (Videx), i-efavirenz (i-Sustiva, e-Atripla), i-etravirine (Intelence), i-indinavir (i-Crixivan), i-lopinavir (e-Kaletra), i-maraviroc (i-Selzentry), i-nelfinavir (i-Viracept), i-nevirapine (i-Viramune), i-rilpivirine (i-Edurant, eComplera), i-ritonavir (i-Norvir, e-Kaletra), ne-saquinavir (i-Invirase); i-rifabutin (i-Mycobutin); i-rifampin (iRifadin, iRimactane, eRifamate, eRifater); i-sildenafil (i-Viagra); i-sirolimus (i-Rapamune); itacrolimus (Prograf); kanye ne-trazodone (Desyrel). Eminye imithi eminingi ingaxhumana ne-delavirdine, ngakho-ke qiniseka ukuthi utshela udokotela wakho ngayo yonke imithi oyiphuzayo, ngisho naleyo engabonakali kulolu hlu. Udokotela wakho angadinga ukushintsha imithamo yemithi yakho noma akuqaphele ngokucophelela ngemiphumela emibi.
- utshele udokotela wakho kanye nosokhemisi ukuthi yimiphi imikhiqizo yamakhambi oyithathayo, ikakhulukazi iSort John's wort. Akufanele uthathe i-wort yaseSt.John ngenkathi uthatha i-delavirdine.
- uma uthatha i-didanosine (Videx), yithathe okungenani ihora eli-1 ngaphambi noma ihora eli-1 ngemuva kokuthatha i-delavirdine.
- uma uthatha ama-antacid, thatha i-antacid okungenani ihora elilodwa ngaphambi noma ihora eli-1 ngemuva kokuthatha i-delavirdine.
- Tshela udokotela wakho uma uke waba ne-achlorhydria (isimo lapho isisu sine-asidi encane noma singenayo) noma isifo sesibindi noma sezinso.
- utshele udokotela wakho uma ukhulelwe noma uhlela ukukhulelwa. Uma ukhulelwa ngenkathi uthatha i-delavirdine, shayela udokotela wakho. Tshela udokotela wakho uma uncelisa. Akufanele uncelise ibele uma utheleleke nge-HIV noma uma udla i-delavirdine.
- kufanele wazi ukuthi amafutha omzimba wakho angakhuphuka noma ahambele ezindaweni ezahlukahlukene zomzimba wakho njengamabele akho, iqolo elingaphezulu nentamo, noma phakathi nendawo yomzimba wakho. Ukulahleka kwamafutha emilenzeni, ezingalweni nasebusweni nakho kungenzeka.
- kufanele wazi ukuthi ngenkathi uthatha imishanguzo yokwelapha ukutheleleka nge-HIV, amasosha omzimba wakho angaqina futhi aqale ukulwa nezinye izifo ezazivele zisemzimbeni wakho. Lokhu kungadala ukuthi ube nezimpawu zalezo zifo. Uma unezimpawu ezintsha noma eziya ziba zimbi ngemuva kokuqala ukwelashwa nge-delavirdine, qiniseka ukuthi utshela udokotela wakho.
Ngaphandle kokuthi udokotela wakho akutshele ngenye indlela, qhubeka nokudla okuvamile.
Thatha umthamo ongabanjwanga ngokushesha nje lapho uwukhumbula. Kodwa-ke, uma sekuyisikhathi somthamo olandelayo, weqa umthamo ongabanjwanga bese uqhubeka neshejuli yakho ejwayelekile yokulinganisa. Ungathathi umthamo ophindwe kabili ukwenza okulahlekile. Uma uphuthelwa imithamo eminingana, shayela udokotela wakho akubuze ukuthi kufanele uqhubeke kanjani nokuthatha i-delavirdine.
I-Delavirdine ingadala imiphumela emibi. Tshela udokotela wakho uma kukhona kulezi zimpawu ezinzima noma ezingapheli:
- ukukhathala ngokweqile
- ikhanda
- isicanucanu
- isifo sohudo
- ukuqubuka
Eminye imiphumela emibi ingaba mibi. Uma uhlangabezana nalezi zimpawu ezilandelayo, yeka ukuthatha i-delavirdine bese ushayela udokotela wakho ngokushesha noma uthole ukwelashwa okuphuthumayo:
- ukuqubuka kanye nezinye izimpawu ezinjengomkhuhlane, ukushwabana, izilonda emlonyeni, amehlo abomvu noma avuvukile, noma ubuhlungu bemisipha noma obuhlangene
- isifuba
- ukulunywa
- ukuvuvukala kobuso, umphimbo, ulimi, izindebe, amehlo, izandla, izinyawo, amaqakala noma imilenze engezansi
- ukushaqeka
- ukuphefumula kanzima noma ukugwinya
I-Delavirdine ingadala eminye imiphumela emibi. Shayela udokotela wakho uma unezinkinga ezingavamile ngenkathi uthatha lo muthi.
Uma uthola imiphumela emibi kakhulu, wena noma udokotela wakho ungathumela umbiko kuhlelo lwe-Food and Drug Administration's (FDA) MedWatch Adverse Event Reporting online (http://www.fda.gov/Safety/MedWatch) noma ngocingo ( 1-800-332-1088).
Gcina le mithi esitsheni efike ngayo, ivalwe ngokuqinile, futhi lapho izingane zingafinyeleleki khona. Gcina ekamelweni lokushisa futhi kude nokushisa okweqile nomswakama (hhayi endlini yangasese).
Imithi engadingeki kufanele ilahlwe ngezindlela ezikhethekile zokuqinisekisa ukuthi izilwane ezifuywayo, izingane nabanye abantu abakwazi ukuzidla. Kodwa-ke, akufanele ukhiphe le mithi ethoyilethi. Esikhundleni salokho, indlela engcono kakhulu yokulahla imithi yakho ngohlelo lokubuyisa umuthi. Khuluma nosokhemisi wakho noma uthinte umnyango wangakini wokulahla udoti / wokusebenzisa kabusha ukuze ufunde ngezinhlelo zokubuyisa emphakathini wakho. Bheka iwebhusayithi yakwa-FDA's Safe Disposal of Medicines (http://goo.gl/c4Rm4p) ukuthola eminye imininingwane uma ungakwazi ukufinyelela kuhlelo lokubuyisa.
Kubalulekile ukugcina yonke imishanguzo ingabonakali futhi ifinyeleleke ezinganeni njengoba iziqukathi eziningi (njengezingqondo zamaphilisi zamasonto onke kanye nalawo amaconsi wamehlo, okhilimu, amabala, kanye nama-inhalers) azimeleki ezinganeni futhi izingane ezincane zingazivula kalula. Ukuvikela izingane ezisencane ekufakeni ubuthi, hlala uvala amakepisi okuphepha bese ubeka umuthi endaweni ephephile - eyodwa ephezulu futhi engekho futhi engabonakali kubo futhi efinyelela kuyo. http://www.upandaway.org
Uma kwenzeka ukweqisa ngokweqile, shayela ucingo losizo lokulawula ubuthi ku-1-800-222-1222. Imininingwane iyatholakala online ku-https: //www.poisonhelp.org/help. Uma isisulu siwile, saba nokuquleka, sinenkinga yokuphefumula, noma singakwazi ukuvuswa, shayela ngokushesha abezimo eziphuthumayo ku-911.
Gcina wonke ama-aphoyintimenti nodokotela wakho kanye nelabhorethri. Udokotela wakho angalawula izivivinyo ezithile zebhu ukuze ahlole impendulo yakho ku-delavirdine.
Ungavumeli omunye umuntu ukuthi athathe imithi yakho. Buza usokhemisi wakho noma imiphi imibuzo onayo mayelana nokugcwalisa umuthi wakho.
Kubalulekile ukuthi ugcine uhlu olubhaliwe lwayo yonke imishanguzo oyisebenzisayo kadokotela kanye nokungabhaliswanga (ngaphezulu kokuthenga), kanye nanoma yimiphi imikhiqizo efana namavithamini, amaminerali, noma ezinye izithako zokudla. Kufanele uze nalolu hlu njalo uma uvakashela udokotela noma uma ungeniswa esibhedlela. Kubaluleke kakhulu futhi nemininingwane ebalulekile ukuthi uphathe uma kwenzeka kunezimo eziphuthumayo.
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