Umlobi: Gregory Harris
Usuku Lokudalwa: 12 Epreli 2021
Ukuvuselela Usuku: 21 Unovemba 2024
Anonim
Amiodarone, Sotalol, and Dofetilide - Class III Antiarrhythmics Mechanism of Action and Side Effects
Ividiyo: Amiodarone, Sotalol, and Dofetilide - Class III Antiarrhythmics Mechanism of Action and Side Effects

-Delile

I-Dofetilide ingadala ukuthi inhliziyo yakho ishaye ngokungafani. Uzodinga ukuba sesibhedlela noma kwenye indawo lapho ungaqashwa khona ngudokotela wakho okungenani izinsuku ezintathu lapho uqala noma uqalwa kabusha ku-dofetilide. Kubalulekile ukufunda imininingwane yesiguli oyinikezwe njalo lapho uqala ukwelashwa nge-dofetilide.

I-Dofetilide isetshenziselwa ukwelapha ukushaya kwenhliziyo okungajwayelekile (kufaka phakathi i-atrial fibrillation noma i-atrial flutter). Kusesigabeni semithi ebizwa ngama-antiarrhythmics. Ithuthukisa isigqi senhliziyo yakho ngokuphumuza inhliziyo eyeqile.

I-Dofetilide iza njengephilisi elizothathwa ngomlomo. Imvamisa iphuzwa kabili ngosuku, kepha ingaphuzwa kanye ngosuku kubantu abanezimo ezithile. Landela izinkomba ezikulebuli kadokotela wakho ngokucophelela, bese ubuza udokotela noma usokhemisi wakho ukuthi akuchaze nganoma iyiphi ingxenye ongayiqondi. Thatha i-dofetilide njengoba nje kuqondisiwe. Ungayithathi kancane noma uyithathe kaningi kunokuyalelwa ngudokotela wakho.

IDofetilide ilawula isigqi senhliziyo esingajwayelekile kepha ayiyelaphi. Qhubeka nokusebenzisa i-dofetilide noma ngabe uzizwa uphilile. Ungayeki ukuthatha i-dofetilide ngaphandle kokukhuluma nodokotela wakho.


Lo muthi kwesinye isikhathi ubekelwa okunye ukusetshenziswa; buza udokotela wakho noma usokhemisi ukuthola eminye imininingwane.

Ngaphambi kokuthatha i-dofetilide,

  • Tshela udokotela kanye nosokhemisi wakho uma unegciwane ku-dofetilide, noma imiphi eminye imithi, noma iziphi izithako ezikuma-capsule e-dofetilide. Buza usokhemisi wakho noma hlola imininingwane yesiguli somkhiqizi ukuthola uhlu lwezithako.
  • Tshela udokotela wakho uma uthatha i-cimetidine (Tagamet), i-dolutegravir (i-Tivicay), i-hydrochlorothiazide (i-Microzide, i-Oretic), i-hydrochlorothiazide ne-triamterene (i-Dyazide, i-Maxzide), i-ketoconazole (i-Nizoral), i-megestrol (i-Megace), i-prochlorperazine (i-Compro, i-trimethoprim (Primsol), i-trimethoprim ne-sulfamethoxazole (i-Bactrim, i-Septra, i-Sulfatrim), ne-verapamil (i-Calan, i-Covera, i-Verelan). Udokotela wakho mhlawumbe uzokutshela ukuthi ungasebenzisi i-dofetilide uma uthatha eyodwa noma ngaphezulu yale mithi.
  • Tshela udokotela wakho kanye nosokhemisi ukuthi imiphi imishanguzo kadokotela neyokungabhalisi, amavithamini, izithako zokudla okunempilo, nemikhiqizo yamakhambi oyithathayo noma ohlela ukuyithatha. Qiniseka ukuthi usho noma ikuphi kokulandelayo: i-amiloride (Midamor); ama-antibiotic afana ne-erythromycin (E.E.S., E-Mycin) ne-norfloxacin (Noroxin); imishanguzo ethile yokulwa nobuthi efana ne-fluconazole (i-Diflucan), i-itraconazole (i-Sporanox), ne-ketoconazole (i-Nizoral); i-bepridil (i-Vascor); ama-cannabinoids afana ne-dronabinol (Marinol), nabilone (Cesamet) noma insangu (insangu); i-digoxin (i-Lanoxin); i-diltiazem (iCardizem, iCartia XT, iDilacor XR, iTaxtia XT, iTiazac); isisu (‘amaphilisi amanzi’); I-HIV protease inhibitors kufaka phakathi i-atazanavir (Reyataz), darunavir (Prezista), fosamprenavir (Lexiva), indinavir (Crixivan), nelfinavir (Viracept), ritonavir (Norvir, eKaletra), saquinavir (Invirase) kanye ne-tipranavir (Aptivus) imithi ye-asthma efana ne-zafirlukast (Accolate); imithi yokudangala, ukugula kwengqondo, noma isicanucanu; imishanguzo yezinhliziyo ezishaya ngokungafani ne-amiodarone (Cordarone, Pacerone); i-metformin (iFortamet, iGlucophage, iGlumetza, iRiomet); nefazodone; noma i-quinine (iQualquin).
  • Tshela udokotela wakho uma ngabe uke waba ne-QT syndrome isikhathi eside (isimo esandisa ingozi yokuhlaselwa ukushaya kwenhliziyo okungajwayelekile okungadala ukuquleka noma ukufa ngokuzuma), noma isifo sezinso.
  • Tshela udokotela wakho uma unesifo sohudo ngokweqile, ukujuluka, ukuhlanza, ukulahlekelwa isifiso sokudla, noma ukunciphisa ukoma noma izinga eliphansi le-potassium egazini lakho, futhi uma ngabe uke waba nesifo senhliziyo noma sesibindi.
  • tshela udokotela wakho uma ukhulelwe, hlela ukukhulelwa, noma uncelisa. Uma ukhulelwa ngenkathi uthatha i-dofetilide, shayela udokotela wakho.

Khuluma nodokotela wakho ngokudla isithelo samagilebhisi noma ukuphuza ijusi lamagilebhisi ngenkathi uthatha i-dofetilide.


Thatha umthamo ongabanjwanga ngokushesha nje lapho uwukhumbula. Kodwa-ke, uma sekuyisikhathi sedosi yakho elandelayo, weqa umthamo ophuthelwe bese uqhubeka nesimiso sakho sokulinganisa. Ungathathi umthamo ophindwe kabili ukwenza okulahlekile.

I-Dofetilide ingadala imiphumela emibi. Tshela udokotela wakho uma kukhona kulezi zimpawu ezinzima noma ezingapheli:

  • ikhanda
  • ubuhlungu besifuba
  • ukuphelelwa umoya
  • isicanucanu
  • izimpawu ezinjengomkhuhlane
  • ubuhlungu besisu
  • ukuhlungu obusemhlane
  • ubunzima bokulala noma ukulala

Uma uhlangabezana nalezi zimpawu ezilandelayo, shayela udokotela wakho ngokushesha:

  • ukushesha, ukushaya ngamandla, noma ukushaya kwenhliziyo okungajwayelekile
  • ukuqubuka
  • isifo sohudo esibi
  • isiyezi noma ukuquleka
  • ukujuluka okungajwayelekile
  • ukuhlanza
  • ukulahlekelwa isifiso sokudla
  • ukoma okwandisiwe (ukuphuza ngaphezu kokujwayelekile)

Uma uthola imiphumela emibi kakhulu, wena noma udokotela wakho ungathumela umbiko kuhlelo lwe-Food and Drug Administration's (FDA) MedWatch Adverse Event Reporting online (http://www.fda.gov/Safety/MedWatch) noma ngocingo ( 1-800-332-1088).


Gcina le mithi esitsheni efike ngayo, ivalwe ngokuqinile, futhi lapho izingane zingafinyeleleki khona. Gcina ekamelweni lokushisa futhi kude nokushisa okweqile nomswakama (hhayi endlini yangasese).

Imithi engadingeki kufanele ilahlwe ngezindlela ezikhethekile zokuqinisekisa ukuthi izilwane ezifuywayo, izingane nabanye abantu abakwazi ukuzidla. Kodwa-ke, akufanele ukhiphe le mithi ethoyilethi. Esikhundleni salokho, indlela engcono kakhulu yokulahla imithi yakho ngohlelo lokubuyisa umuthi. Khuluma nosokhemisi wakho noma uthinte umnyango wangakini wokulahla udoti / wokusebenzisa kabusha ukuze ufunde ngezinhlelo zokubuyisa emphakathini wakho. Bheka iwebhusayithi yakwa-FDA's Safe Disposal of Medicines (http://goo.gl/c4Rm4p) ukuthola eminye imininingwane uma ungakwazi ukufinyelela kuhlelo lokubuyisa.

Kubalulekile ukugcina yonke imishanguzo ingabonakali futhi ifinyeleleke ezinganeni njengoba iziqukathi eziningi (njengezingqondo zamaphilisi zamasonto onke kanye nalawo amaconsi wamehlo, okhilimu, amabala, kanye nama-inhalers) azimeleki ezinganeni futhi izingane ezincane zingazivula kalula. Ukuvikela izingane ezisencane ekufakeni ubuthi, hlala uvala amakepisi okuphepha bese ubeka umuthi endaweni ephephile - eyodwa ephezulu futhi engekho futhi engabonakali kubo futhi efinyelela kuyo. http://www.upandaway.org

Uma kwenzeka ukweqisa ngokweqile, shayela ucingo losizo lokulawula ubuthi ku-1-800-222-1222. Imininingwane iyatholakala online ku-https: //www.poisonhelp.org/help. Uma isisulu siwile, saba nokuquleka, sinenkinga yokuphefumula, noma singakwazi ukuvuswa, shayela ngokushesha abezimo eziphuthumayo ku-911.

Gcina wonke ama-aphoyintimenti nodokotela wakho kanye nelabhorethri. Isigqi senhliziyo yakho kufanele sihlolwe njalo ukuthola impendulo yakho ku-dofetilide. Udokotela wakho uzophinde afune ukulandela ukusebenza kwezinso zakho kanye nezinga legazi le-potassium eduze ngenkathi uthatha i-dofetilide.

Ungavumeli omunye umuntu ukuthi athathe imithi yakho. Buza usokhemisi wakho noma imiphi imibuzo onayo mayelana nokugcwalisa umuthi wakho.

Kubalulekile ukuthi ugcine uhlu olubhaliwe lwayo yonke imishanguzo oyisebenzisayo kadokotela kanye nokungabhaliswanga (ngaphezulu kokuthenga), kanye nanoma yimiphi imikhiqizo efana namavithamini, amaminerali, noma ezinye izithako zokudla. Kufanele uze nalolu hlu njalo uma uvakashela udokotela noma uma ungeniswa esibhedlela. Kubaluleke kakhulu futhi nemininingwane ebalulekile ukuthi uphathe uma kwenzeka kunezimo eziphuthumayo.

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