Ibandronate

-Delile

• Ibandronate ingahle ingasebenzi kahle futhi ingalimaza i-esophagus (ithubhu phakathi komlomo nesisu) noma ibangele izilonda emlonyeni uma ingathathwa ngokwemiyalelo elandelayo. Tshela udokotela wakho uma ungaqondi, awucabangi ukuthi uzokhumbula, noma awukwazi ukulandela le miyalo:
• Ngaphambi kokuthatha ibandronate,
• Ibandronate ingadala imiphumela emibi. Tshela udokotela wakho uma kukhona kulezi zimpawu ezinzima noma ezingapheli:
• Eminye imiphumela emibi ingaba mibi. Uma uhlangabezana nalezi zimpawu ezilandelayo, shayela udokotela wakho ngokushesha ngaphambi kokuthi uthathe enye ibandronate:
• Izimpawu zokudlula ngokweqile zingafaka okulandelayo:

Ibandronate isetshenziselwa ukuvimbela nokwelapha i-osteoporosis (isimo lapho amathambo eba mncane futhi abuthakathaka futhi aphuke kalula) kwabesifazane asebedlule esikhathini ('' ushintsho lwempilo, '' ukuphela kwezikhathi zokuya esikhathini). Ibandronate isekilasini lemithi ebizwa ngama-bisphosphonates. Isebenza ngokuvimbela ukuwohloka kwamathambo nokwandisa ukuminyana kwethambo (ukujiya).

Ibandronate iza njengethebhulethi ukuthatha ngomlomo. Ithebhulethi engu-2.5-mg ivame ukuthathwa kanye ngosuku ekuseni esiswini esingenalutho futhi ithebhulethi engu-150-mg ivame ukuthathwa kanye ngenyanga ekuseni esiswini esingenalutho. Ithebhulethi engu-150-mg kufanele ithathwe ngosuku olufanayo inyanga ngayinye. Landela izinkomba ezikulebuli kadokotela wakho ngokucophelela, bese ubuza udokotela noma usokhemisi wakho ukuthi akuchaze nganoma iyiphi ingxenye ongayiqondi. Thatha ibandronate njengoba nje kuqondisiwe. Ungayithathi kancane noma uyithathe kaningi kunokuyalelwa ngudokotela wakho.

Ibandronate ingahle ingasebenzi kahle futhi ingalimaza i-esophagus (ithubhu phakathi komlomo nesisu) noma ibangele izilonda emlonyeni uma ingathathwa ngokwemiyalelo elandelayo. Tshela udokotela wakho uma ungaqondi, awucabangi ukuthi uzokhumbula, noma awukwazi ukulandela le miyalo:

• Kumele uthathe ibandronate ngemuva nje kokuvuka embhedeni ekuseni, ngaphambi kokudla noma ukuphuza noma yini. Ungalokothi uthathe ibandronate ngesikhathi sokulala noma ngaphambi kokuba uvuke uvuke embhedeni usuku lonke.
• Gwinya amaphilisi ngengilazi egcwele (ama-ounces ayisithupha kuya kwayi-8 (amamitha ayi-180 kuye kwangama-240) wamanzi angenalutho. Ungalokothi uthathe ibandronate netiye, ikhofi, ujusi, ubisi, amanzi amaminerali, amanzi akhazimulayo, nanoma yiluphi uketshezi ngaphandle kwamanzi angenalutho.
• Gwinya wonke amaphilisi; ungawahlukanisi, ungawahlafune noma uwagxoze. Ungamunci amaphilisi.
• Ngemuva kokuthatha ibandronate, ungadli, ungaphuzi, noma uthathe noma imuphi omunye umuthi (kufaka phakathi amavithamini noma ama-antacids) okungenani imizuzu engama-60. Musa ukulala phansi okungenani imizuzu engama-60 ngemuva kokuthatha ibandronate. Hlala uqonde noma ume uqonde okungenani imizuzu engama-60.

Ibandronate control osteoporosis kepha ayiyelaphi. Ibandronate iyasiza ekwelapheni nasekuvimbeleni i-osteoporosis kuphela uma nje ithathwa njalo. Qhubeka uthathe ibandronate noma ngabe uzizwa uphilile. Ungayeki ukuthatha ibandronate ngaphandle kokukhuluma nodokotela wakho, kodwa khuluma nodokotela wakho ngezikhathi ezithile mayelana nokuthi ngabe usadinga ukuthatha ibandronate.

Udokotela wakho noma usokhemisi uzokunikeza ishidi lemininingwane yesiguli lomkhiqizi (Umhlahlandlela Wezokwelapha) lapho uqala ukwelashwa nge-ibandronate futhi isikhathi ngasinye lapho ugcwalisa umuthi wakho. Funda imininingwane ngokucophelela bese ubuza udokotela noma usokhemisi wakho uma unemibuzo. Ungavakashela futhi iwebhusayithi ye-Food and Drug Administration (FDA) (http://www.fda.gov/Drugs/DrugSafety/ucm085729.htm) noma iwebhusayithi yomkhiqizi ukuthola i-Medication Guide.

Lo muthi ungabekelwa okunye ukusetshenziswa; buza udokotela wakho noma usokhemisi ukuthola eminye imininingwane.

Ngaphambi kokuthatha ibandronate,

• Tshela udokotela wakho kanye nosokhemisi uma unegciwane ku-ibandronate, noma imiphi eminye imithi, noma iziphi izithako ezisezibhebheni ze-ibandronate. Buza usokhemisi wakho ukuthola uhlu lwezithako.
• Tshela udokotela wakho kanye nosokhemisi ukuthi imiphi imishanguzo kadokotela neyokungabhalisi, amavithamini, izithako zokudla okunempilo, nemikhiqizo yamakhambi oyithathayo noma ohlela ukuyithatha. Qiniseka ukuthi usho noma yikuphi kokulandelayo: i-angiogenesis inhibitors efana ne-bevacizumab (Avastin), everolimus (Afinitor, Zortress), pazopanib (Votrient), sorafenib (Nexavar), noma sunitinib (Sutent); i-aspirin nezinye izidakamizwa ezingezona ukuvuvukala (ama-NSAID) njenge-ibuprofen (Advil, Ibu-Tab, Motrin, abanye) kanye ne-naproxen (Aleve, Naprelan, Naprosyn, abanye); i-chemotherapy yomdlavuza; kanye ne-steroids yomlomo efana ne-dexamethasone, i-methylprednisolone (i-Medrol), ne-prednisone (i-Rayos). Udokotela wakho angadinga ukushintsha imithamo yemithi yakho noma akuqaphele ngokucophelela ngemiphumela emibi.
• uma uthatha noma yimiphi imithi yomlomo, kufaka phakathi izithasiselo, amavithamini, noma ama-antacids, thatha okungenani imizuzu engama-60 ngemuva kokuthatha ibandronate.
• Tshela udokotela wakho uma ungakwazi ukuhlala uqonde noma ume mpo okungenani imizuzu engama-60 futhi uma uke waba nezinga eliphansi le-calcium egazini lakho noma. Udokotela wakho angakutshela ukuthi ungathathi ibandronate.
• utshele udokotela wakho uma uthola ukwelashwa ngemisebe futhi uma uke waba nayo noma wake waba ne-anemia (isimo lapho amangqamuzana abomvu egazi engalethi umoya-mpilo owenele kuzo zonke izingxenye zomzimba); ubunzima bokugwinya; isilungulela; izilonda noma ezinye izinkinga ngesisu sakho noma ngesifo (ishubhu elixhumanisa umphimbo nesisu); umdlavuza; noma yiluphi uhlobo lokutheleleka, ikakhulukazi emlonyeni wakho; izinkinga ngomlomo wakho, ngamazinyo, noma ngezinsini; noma isiphi isimo esivimba igazi lakho ekunqandeni ngokujwayelekile; noma isifo sezinso.
• utshele udokotela wakho uma ukhulelwe, hlela ukukhulelwa, noma uncelisa. Tshela nodokotela wakho uma uhlela ukukhulelwa nganoma yisiphi isikhathi ngokuzayo, ngoba ibandronate ingahlala emzimbeni wakho iminyaka ngemuva kokuyeka ukuyithatha. Shayela udokotela wakho uma ukhulelwa ngesikhathi noma ngemuva kokwelashwa kwakho.
• kufanele wazi ukuthi ibandronate ingadala i-osteonecrosis yomhlathi (i-ONJ, isimo esibi sethambo lomhlathi), ikakhulukazi uma uhlinzeka ngamazinyo noma welashwa ngenkathi uthatha umuthi. Udokotela wamazinyo kufanele ahlole amazinyo akho futhi enze noma yiziphi izindlela zokwelashwa ezidingekayo, kufaka phakathi ukuhlanza noma ukulungisa amazinyo okufakelwa angalungile, ngaphambi kokuba uqale ukuthatha ibandronate. Qiniseka ukuthi uxubha amazinyo futhi uhlanza umlomo wakho kahle ngenkathi uthatha ibandronate. Khuluma nodokotela wakho ngaphambi kokuthola noma yikuphi ukwelashwa kwamazinyo ngenkathi uthatha lo muthi.
• kufanele wazi ukuthi ibandronate ingadala ubuhlungu obukhulu bethambo, imisipha, noma amalunga. Ungaqala ukuzwa lobu buhlungu kungakapheli izinsuku, izinyanga, noma iminyaka ngemuva kokuqala kwakho ukuthatha ibandronate. Yize lolu hlobo lobuhlungu lungaqala ngemuva kokuthi uthathe i-ibandronate isikhathi esithile, kubalulekile ukuthi wena nodokotela wakho nazi ukuthi kungabangelwa yi-ibandronate. Shayela udokotela wakho ngokushesha uma uzwa ubuhlungu obukhulu noma kunini ngesikhathi sokwelashwa kwakho nge-ibandronate. Udokotela wakho angakutshela ukuthi uyeke ukuthatha i-ibandronate futhi ubuhlungu bakho bungaphela ngemuva kokuyeka ukuthatha umuthi.
• khuluma nodokotela wakho ngezinye izinto ongazenza ukuvimbela ukukhumuzeka kwamathambo ekukhuleni noma ekukhuleni. Udokotela wakho mhlawumbe uzokutshela ukuthi ugweme ukubhema nokuphuza utshwala obuningi futhi ulandele uhlelo olujwayelekile lokuzivocavoca umzimba.

Kufanele udle futhi uphuze ukudla okuningi neziphuzo ezicebile nge-calcium novithamini D ngenkathi uthatha ibandronate. Udokotela wakho uzokutshela ukuthi yikuphi ukudla neziphuzo okungumthombo omuhle walezi zinongo nokuthi zingaki izinsizakalo ozidingayo usuku ngalunye. Uma ukuthola kunzima ukudla okwanele kulokhu kudla, tshela udokotela wakho. Uma kunjalo, udokotela wakho angakunikeza noma ancome ukuthi kufakwe isengezo.

Uma ukhohlwa ukuthatha ithebhulethi yansuku zonke engu-2.5-mg, ungayithathi ngokuhamba kosuku. Yeqa umthamo ophuthelwe bese uqhubeka nesimiso sakho sokulinganisa okujwayelekile ngakusasa ekuseni. Ungathathi amaphilisi amabili e-ibandronate ngosuku olufanayo.

Uma ukhohlwa ukuthatha ithebhulethi ye-150-mg kanye ngenyanga, futhi usuku lwakho olulandelayo oluhlelelwe ukuthatha ibandronate lungaphezu kwezinsuku eziyi-7, thatha ithebhulethi eyodwa ekuseni ngemuva kokukhumbula. Bese ubuyela ekuthatheni ithebhulethi eyodwa njalo ngenyanga ngosuku oluhleliwe njalo. Uma ukhohlwa ukuthatha ithebhulethi ye-150-mg kanye kanye nosuku lwakho olulandelayo lokuthatha ibandronate kusele izinsuku eziyi-7 noma ezimbalwa, yeqa umthamo bese ulinda usuku lwakho olulandelayo oluhleliwe. Akufanele uthathe amaphilisi amabili we-150-mg we-ibandronate kungakapheli isonto elilodwa.

Uma ungaqiniseki ukuthi wenzeni uma uphuthelwa umthamo we-ibandronate, shayela udokotela wakho.

Ibandronate ingadala imiphumela emibi. Tshela udokotela wakho uma kukhona kulezi zimpawu ezinzima noma ezingapheli:

• isicanucanu
• ubuhlungu besisu
• isifo sohudo
• ukuqunjelwa
• ubuthakathaka
• isiyezi
• ikhanda
• umkhuhlane, umphimbo obuhlungu, amakhaza, ukukhwehlela, nezinye izimpawu zokutheleleka
• kaningi noma ngokuphuthumayo isidingo sokuchama
• ukuchama kabuhlungu

Eminye imiphumela emibi ingaba mibi. Uma uhlangabezana nalezi zimpawu ezilandelayo, shayela udokotela wakho ngokushesha ngaphambi kokuthi uthathe enye ibandronate:

• isilungulela esisha noma esiba sibi kakhulu
• ubunzima bokugwinya
• ubuhlungu ngokugwinya
• ubuhlungu besifuba esingenhla
• ukuqubuka
• izinsini ezibuhlungu noma ezivuvukele
• ukukhululeka kwamazinyo
• ukuba ndikindiki noma ukuzwa okusindayo emhlathini
• ukwelashwa kabi komhlathi
• ubuhlungu obubuhlungu, obuhlungu ezinqulwini, emgodini, noma emathangeni

Ibandronate ingadala eminye imiphumela emibi. Shayela udokotela wakho uma unezinkinga ezingavamile ngenkathi uthatha lo muthi.

Ukuthatha imithi ye-bisphosphonate efana ne-ibandronate ye-osteoporosis kungakhuphula ubungozi bokuthi uzophula amathambo akho ethanga. Ungabuzwa ubuhlungu okhalweni lwakho, emgodini, noma emathangeni amasonto ambalwa noma izinyanga ngaphambi kokuphuka kwamathambo, futhi ungathola ukuthi elilodwa noma womabili amathambo akho ethanga aphukile yize ungazange uwe noma wehlelwe okunye ukuhlukumezeka. Akujwayelekile ukuthi ithambo lamathanga liphuke kubantu abaphilile, kepha abantu abane-osteoporosis bangaliphula leli thambo noma bengayithathi ibandronate. Khuluma nodokotela wakho ngezingozi zokuthatha ibandronate.

Uma uthola imiphumela emibi kakhulu, wena noma udokotela wakho ungathumela umbiko kuhlelo lwe-Food and Drug Administration's (FDA) MedWatch Adverse Event Reporting online (http://www.fda.gov/Safety/MedWatch) noma ngocingo ( 1-800-332-1088).

Gcina le mithi esitsheni efike ngayo, ivalwe ngokuqinile, futhi lapho izingane zingafinyeleleki khona. Gcina ekamelweni lokushisa futhi kude nokushisa okweqile nomswakama (hhayi endlini yangasese).

Imithi engadingeki kufanele ilahlwe ngezindlela ezikhethekile zokuqinisekisa ukuthi izilwane ezifuywayo, izingane nabanye abantu abakwazi ukuzidla. Kodwa-ke, akufanele ukhiphe le mithi ethoyilethi. Esikhundleni salokho, indlela engcono kakhulu yokulahla imithi yakho ngohlelo lokubuyisa umuthi. Khuluma nosokhemisi wakho noma uthinte umnyango wangakini wokulahla udoti / wokusebenzisa kabusha ukuze ufunde ngezinhlelo zokubuyisa emphakathini wakho. Bheka iwebhusayithi yakwa-FDA's Safe Disposal of Medicines (http://goo.gl/c4Rm4p) ukuthola eminye imininingwane uma ungakwazi ukufinyelela kuhlelo lokubuyisa.

Kubalulekile ukugcina yonke imishanguzo ingabonakali futhi ifinyeleleke ezinganeni njengoba iziqukathi eziningi (njengezingqondo zamaphilisi zamasonto onke kanye nalawo amaconsi wamehlo, okhilimu, amabala, kanye nama-inhalers) azimeleki ezinganeni futhi izingane ezincane zingazivula kalula. Ukuvikela izingane ezisencane ekufakeni ubuthi, hlala uvala amakepisi okuphepha bese ubeka umuthi endaweni ephephile - eyodwa ephezulu futhi engekho futhi engabonakali kubo futhi efinyelela kuyo. http://www.upandaway.org

Uma kwenzeka ukweqisa ngokweqile, nikeza isisulu ingilazi egcwele yobisi bese ushayela isikhungo sendawo sakho sokulawula ubuthi ku-1-800-222-1222. Uma isisulu siwile noma singaphefumuli, shayela abezimo eziphuthumayo zendawo ku-911. Ungavumeli isisulu ukuba silale phansi futhi ungazami ukwenza isisulu sihlanze.

Izimpawu zokudlula ngokweqile zingafaka okulandelayo:

• isicanucanu
• ubuhlungu besisu
• isilungulela

Gcina wonke ama-aphoyintimenti nodokotela wakho. Udokotela wakho angalawula izivivinyo ezithile ukuze ahlole impendulo yomzimba wakho ku-ibandronate.

Ngaphambi kokwenza ucwaningo lwamathambo, tshela udokotela nabasebenzi bezempilo ukuthi uthatha ibandronate.

Ungavumeli omunye umuntu ukuthi athathe imithi yakho. Buza usokhemisi wakho noma imiphi imibuzo onayo mayelana nokugcwalisa umuthi wakho.

Kubalulekile ukuthi ugcine uhlu olubhaliwe lwayo yonke imishanguzo oyisebenzisayo kadokotela kanye nokungabhaliswanga (ngaphezulu kokuthenga), kanye nanoma yimiphi imikhiqizo efana namavithamini, amaminerali, noma ezinye izithako zokudla. Kufanele uze nalolu hlu njalo uma uvakashela udokotela noma uma ungeniswa esibhedlela. Kubaluleke kakhulu futhi nemininingwane ebalulekile ukuthi uphathe uma kwenzeka kunezimo eziphuthumayo.

• UBoniva^®