Inaliti ye-Pegfilgrastim

-Delile

• Uma une-pegfilgrastim eyenzelwe ukufaka umjovo othomathikhi endaweni;
• Ngaphambi kokusebenzisa imikhiqizo yomjovo we-pegfilgrastim,
• Imikhiqizo yomjovo wePegfilgrastim ingadala imiphumela emibi. Tshela udokotela wakho uma kukhona kulezi zimpawu ezinzima noma ezingapheli:
• Eminye imiphumela emibi ingaba mibi. Uma uhlangabezana nenye yalezi zimpawu, shayela udokotela wakho ngokushesha:
• Izimpawu zokudlula ngokweqile zingafaka okulandelayo:

Umjovo we-Pegfilgrastim, i-pegfilgrastim-bmez, i-pegfilgrastim-cbqv, nomjovo we-pegfilgrastim-jmdb yimithi ye-biologic (imithi eyenziwe ngezinto eziphilayo). I-biosimilar pegfilgrastim-bmez, i-pegfilgrastim-cbqv, ne-pegfilgrastim-jmdb injection ifana kakhulu nomjovo we-pegfilgrastim futhi isebenza ngendlela efanayo nomjovo we-pegfilgrastim emzimbeni. Ngakho-ke, igama elithi pegfilgrastim imikhiqizo yomjovo izosetshenziselwa ukumela le mithi kule ngxoxo.

Imikhiqizo yomjovo wePegfilgrastim isetshenziselwa ukunciphisa amathuba okutheleleka kubantu abanezinhlobo ezithile zomdlavuza futhi abathola imishanguzo yokwelapha ngamakhemikhali enganciphisa inani lama-neutrophils (uhlobo lweseli legazi elidingekayo ukulwa nokutheleleka). Umjovo wePegfilgrastim (Neulasta) nawo usetshenziselwa ukwandisa amathuba okusinda kubantu abaye bavezwa yimisebe eyingozi, engadala umonakalo omkhulu futhi osongela impilo emnkantsheni wethambo. I-Pegfilgrastim isekilasini lemithi ebizwa ngama-colony factor stimulating. Isebenza ngokusiza umzimba ukuthi wenze ama-neutrophil amaningi.

Imikhiqizo yomjovo wePegfilgrastim iza njengesisombululo (uketshezi) emijovweni efakwe umjovo ekhethiwe ukujova ngomgogodla (ngaphansi kwesikhumba), nasethungelweni lomjovo othomathikhi ozenzekelayo (on-body injector) ukufaka esikhunjeni. Uma usebenzisa umjovo we-pegfilgrastim ukunciphisa ubungozi bokutheleleka ngesikhathi se-chemotherapy, uvame ukunikezwa njengomthamo owodwa kumjikelezo we-chemotherapy ngamunye, kungakapheli amahora angama-24 ngemuva kokuba umthamo wokugcina we-chemotherapy womjikelezo unikiwe futhi ngaphezulu kwe-14 izinsuku ngaphambi kokuqala umjikelezo olandelayo we-chemotherapy. Uma usebenzisa umjovo we-pegfilgrastim ngoba uvezwe kumanani ayingozi emisebe, ivame ukunikezwa njengemithamo emi-2 eyodwa, ngeviki eli-1 ukuqhela. Udokotela wakho uzokutshela kahle ukuthi kufanele usebenzise nini umjovo we-pegfilgrastim.

Imikhiqizo yokujova i-Pegfilgrastim ungayinikwa ngumhlengikazi noma omunye umhlinzeki wezokunakekelwa kwempilo, ungatshelwa ukuthi ujove umuthi ngokwakho ekhaya, noma ungathola umshini ozisebenzelayo wokujova othomathikhi ngumhlengikazi noma umhlinzeki wezokunakekelwa kwempilo ozojova umuthi ngokuzenzakalela wena ekhaya. Uma uzobe ujova imikhiqizo yomjovo we-pegfilgrastim ngokwakho ekhaya, noma uma uthola okokufaka okuzenzakalelayo komjovo othomathikhi, umhlinzeki wezokunakekelwa kwezempilo uzokukhombisa ukuthi ungawujova kanjani umuthi, noma ukuthi ungayiphatha kanjani le divayisi. Umhlinzeki wakho wezokunakekelwa kwempilo uzokunikeza nemininingwane yomkhiqizi yesiguli. Cela umhlinzeki wakho wezokunakekelwa kwempilo akuchaze nganoma iyiphi ingxenye ongayiqondi. Sebenzisa umkhiqizo womjovo we-pegfilgrastim njengoba nje uqondisiwe. Ungayisebenzisi ngaphezulu noma ngaphansi kwayo noma uyisebenzise kaningi kunokuyalelwa ngudokotela wakho.

Unganyakazisi imijovo equkethe isisombululo se-pegfilgrastim. Njalo bheka isisombululo se-pegfilgrastim ngaphambi kokujova. Ungayisebenzisi uma usuku lokuphelelwa yisikhathi seludlulile, noma uma isisombululo se-pegfilgrastim sinezinhlayiya noma sibukeka sinamafu noma sikhanyayo.

Uma isisombululo sakho se-pegfilgrastim singena kusetshenziswa somjovo othomathikhi ozenzekelayo, ngokuvamile le divayisi izosetshenziswa esiswini sakho noma ngemuva kwengalo yakho ngumhlengikazi noma omunye umhlinzeki wezokunakekelwa kwempilo ngosuku olungaphambi kokuthola i-pegfilgrastim. Ngosuku olulandelayo (cishe amahora angama-27 ngemuva kokufakwa kwesisetshenziswa somjovo othomathikhi esikhunjeni sakho), umthamo wesisombululo se-pegfilgrastim uzofakwa ngokuzenzekelayo ngaphansi kwemizuzu engama-45.

Uma une-pegfilgrastim eyenzelwe ukufaka umjovo othomathikhi endaweni;

• kufanele ube nomnakekeli nawe okokuqala lapho uthola isilinganiso se-pegfilgrastim noma nganoma isiphi isikhathi lapho kusetshenziswe khona umjovo othomathikhi ozenzakalelayo ngemuva kwengalo yakho.
• uzodinga ukuqapha idivayisi yomjovo othomathikhi oyifakile ngenkathi umthamo wonke we-pegfilgrastim ufakwa emzimbeni wakho, ngakho-ke kufanele ugweme imisebenzi nokuba sezindaweni ezingaphazamisa ukuqapha ngenkathi uthola umthamo we-filgrastim kanye nehora eli-1 ngemuva kwalokho.
• akufanele uhambe, ushayele imoto, noma usebenzise imishini ehoreni eli-1 ngaphambi nangemva kwamahora ama-2 ngemuva kokuthola umthamo wakho we-pegfilgrastim ngedivayisi yomjovo othomathikhi oyifakile (cishe amahora angama-26 kuye kwangama-29 ngemuva kokuthi ifakiwe).
• kufanele uqiniseke ukuthi ugcine okokufaka okuzenzakalelayo komjovo ozenzakalelayo okungenani amasentimitha ama-4 kude nezinto zikagesi kanye nemishini kubandakanya omakhalekhukhwini, izingcingo ezingenantambo, namahhavini ama-microwave.
• kufanele ugweme ama-x-ray esikhumulweni sezindiza futhi ucele ukubambeka mathupha phansi uma kufanele uhambe ngemuva kokufakwa komshini othomathikhi ozenzakalelayo emzimbeni wakho nangaphambi kokuba uthole umthamo wakho we-pegfilgrastim.
• kufanele ususe ngokushesha idivaysi yomjovo othomathikhi oyifakile uma une-allergen reaction ngenkathi uthola umthamo wakho we-pegfilgrastim ngokubamba onqenqemeni lwephedi yokunamathisela bese uyixebula. Shayela udokotela wakho ngokushesha futhi uthole ukwelashwa okuphuthumayo.
• kufanele ushayele udokotela wakho ngokushesha uma idivaysi yomjovo othomathikhi oyithandayo iphuma esikhunjeni sakho, uma i-adhesive iba manzi ngokuphawulekayo, uma ubona kuconsa kusuka kudivayisi, noma uma ukukhanya kwesimo kukhanya kubomvu. Kufanele ugcine idivayisi yomjovo othomathikhi oyifakile yomile amahora amathathu ngaphambi kokuthola umthamo wakho we-pegfilgrastim ukukusiza uqaphele uma ngabe idivayisi yakho iqala ukuvuza ngenkathi uthola umthamo wakho.
• kufanele ugweme ukuvezwa ezifundweni zezithombe zezokwelapha (ukuskena kwe-X-ray, i-MRI, i-CT scan, i-ultrasound) noma izindawo ezicebile zomoya-mpilo (amakamelo we-hyperbaric).
• kufanele ugweme ukulala noma ukufaka ingcindezi kudivayisi yomjovo othomathikhi oyithandayo.
• kufanele ugweme amabhavu ashisayo, izivunguvungu, ama-sauna, nelanga eliqondile.
• kufanele ugweme ukusebenzisa ama-lotion, uwoyela, okhilimu, nabahlanzayo esikhunjeni sakho eduze kwensiza yomjovo othomathikhi oyithandayo

Uma idivaysi yomjovo othomathikhi egcotshwa kuqala ibenyezela ngokubomvu, uma ngabe le divayisi iphuma ngaphambi kokulethwa komthamo ogcwele, noma uma isinamathelisi esikule divayisi simanzi noma kuvuza, shayela udokotela wakho khona manjalo. Kungenzeka ukuthi awutholanga umthamo ophelele we-pegfilgrastim, futhi ungadinga umthamo owengeziwe.

Lahla izinaliti, imijovo, namadivayisi esitsheni esingamelana nokubhoboza. Khuluma nodokotela wakho noma usokhemisi mayelana nokuthi ungasilahla kanjani isitsha esingamelana nokubhoboza.

Lo muthi ungabekelwa okunye ukusetshenziswa; buza udokotela wakho noma usokhemisi ukuthola eminye imininingwane.

Ngaphambi kokusebenzisa imikhiqizo yomjovo we-pegfilgrastim,

• Tshela udokotela wakho kanye nosokhemisi uma ungenwe i-pegfilgrastim, i-pegfilgrastim-bmez, i-pegfilgrastim-cbqv, i-pegfilgrastim-jmdb, i-filgrastim (i-Granix, i-Neupogen, i-Nivestym, i-Zarxio), noma imuphi omunye umuthi, noma iziphi izithako ezikwi-pegfilast product. Phinda utshele udokotela wakho uma wena noma umuntu ozokujova ngomjovo we-pegfilgrastim wakho uxabana nezinamathiselo ze-latex noma ze-acrylic.
• Tshela udokotela wakho kanye nosokhemisi ukuthi imiphi imishanguzo kadokotela neyokungabhalisi, amavithamini, izithako zokudla okunempilo, nemikhiqizo yamakhambi oyithathayo noma ohlela ukuyithatha. Udokotela wakho angadinga ukushintsha imithamo yemithi yakho noma akuqaphele ngokucophelela ngemiphumela emibi.
• Tshela udokotela wakho uma uke waba nomdlavuza wegazi noma umnkantsha, noma i-myelodysplasia (izinkinga ngamangqamuzana omnkantsha angahle abe yi-leukemia).
• Tshela udokotela wakho uma unesifo se-sickle cell (isifo segazi esingadala izingqinamba ezibuhlungu, inani eliphansi lamaseli abomvu egazi, ukutheleleka, nokulimala ezithweni zangaphakathi). Uma unesifo se-sickle cell, ungahle ube nenkinga ngesikhathi sokwelashwa kwakho ngomkhiqizo womjovo we-pegfilgrastim. Shayela udokotela wakho ngokushesha uma unenkinga yeseli yesikela ngesikhathi sokwelashwa kwakho.
• utshele udokotela wakho uma ukhulelwe, hlela ukukhulelwa, noma uncelisa. Uma ukhulelwa ngenkathi usebenzisa umkhiqizo womjovo we-pegfilgrastim, shayela udokotela wakho.
• kufanele wazi ukuthi imikhiqizo yomjovo we-pegfilgrastim inciphisa ubungozi bokutheleleka kepha ayivimbeli konke ukutheleleka okungakhula phakathi noma ngemuva kwe-chemotherapy. Shayela udokotela wakho uma uba nezimpawu zokutheleleka ezifana nomkhuhlane; Ukugodola; ukuqubuka; Umphimbo obuhlungu; isifo sohudo; noma ububomvu, ukuvuvukala, noma ubuhlungu obuzungeze ukusika noma ubuhlungu.

Ngaphandle kokuthi udokotela wakho akutshele ngenye indlela, qhubeka nokudla okuvamile.

Uma uzobe ujova umkhiqizo womjovo we-pegfilgrastim ekhaya, khuluma nodokotela wakho ngalokho okufanele ukwenze uma ukhohlwa ukujova umuthi ngesikhathi esifanele.

Imikhiqizo yomjovo wePegfilgrastim ingadala imiphumela emibi. Tshela udokotela wakho uma kukhona kulezi zimpawu ezinzima noma ezingapheli:

• ubuhlungu bamathambo
• ubuhlungu ezingalweni noma emilenzeni

Eminye imiphumela emibi ingaba mibi. Uma uhlangabezana nenye yalezi zimpawu, shayela udokotela wakho ngokushesha:

• ubuhlungu engxenyeni engenhla yesobunxele yesisu noma ngasesiphethweni sehlombe lakho lesobunxele
• umkhuhlane, ukuphefumula okuncane, ukukhathazeka ngokuphefumula, ukuphefumula okusheshayo
• ukuvuvukala kobuso, umphimbo, noma ukuzungeza umlomo noma amehlo, isifuba, ukuqubuka, ukulunywa, inkinga ukugwinya noma ukuphefumula
• ukuvuvukala kobuso bakho noma amaqakala, umchamo onegazi noma omnyama, wehlise ukuchama
• umkhuhlane, ubuhlungu besisu, iqolo, ukuzizwa ungaphilile
• ukuvuvukala kwendawo yesisu noma okunye ukuvuvukala, ukuncipha kokuchama, ukuphefumula kanzima, isiyezi, ukukhathala

Imikhiqizo yomjovo wePegfilgrastim ingadala eminye imiphumela emibi. Shayela udokotela wakho uma unezinkinga ezingavamile ngenkathi uthatha lo muthi.

Gcina le mithi ebhokisini efike kuyo, ivalwe ngokuqinile, futhi lapho izingane zingafinyeleleki khona. Gcina imikhiqizo yomjovo we-pegfilgrastim esiqandisini kodwa ungayigodisi. Uma ngephutha umisa umuthi, ungawuvumela ukuthi uncibilike esiqandisini. Kodwa-ke, uma ufaka umjovo ofanayo wemithi okwesibili, kufanele ulahle leyo syringe. Imikhiqizo yomjovo wePegfilgrastim (isirinji ekhethiwe ye-Neulasta, i-Udenyca) ingagcinwa ekamelweni lokushisa kuze kufinyelele emahoreni angama-48, kanti umjovo we-pegfilgrastim (iFulphila) ungagcinwa ekamelweni lokushisa kuze kube amahora angama-72. Imikhiqizo yomjovo wePegfilgrastim kufanele igcinwe kude nelanga eliqondile.

Imithi engadingeki kufanele ilahlwe ngezindlela ezikhethekile zokuqinisekisa ukuthi izilwane ezifuywayo, izingane nabanye abantu abakwazi ukuzidla. Kodwa-ke, akufanele ukhiphe le mithi ethoyilethi. Esikhundleni salokho, indlela engcono kakhulu yokulahla imithi yakho ngohlelo lokubuyisa umuthi. Khuluma nosokhemisi wakho noma uthinte umnyango wangakini wokulahla udoti / wokusebenzisa kabusha ukuze ufunde ngezinhlelo zokubuyisa emphakathini wakho. Bheka iwebhusayithi yakwa-FDA's Safe Disposal of Medicines (http://goo.gl/c4Rm4p) ukuthola eminye imininingwane uma ungakwazi ukufinyelela kuhlelo lokubuyisa.

Kubalulekile ukugcina yonke imishanguzo ingabonakali futhi ifinyeleleke ezinganeni njengoba iziqukathi eziningi (njengezingqondo zamaphilisi zamasonto onke kanye nalawo amaconsi wamehlo, okhilimu, amabala, kanye nama-inhalers) azimeleki ezinganeni futhi izingane ezincane zingazivula kalula. Ukuvikela izingane ezisencane ekufakeni ubuthi, hlala uvala amakepisi okuphepha bese ubeka umuthi endaweni ephephile - eyodwa ephezulu futhi engekho futhi engabonakali kubo futhi efinyelela kuyo. http://www.upandaway.org

Uma kwenzeka ukweqisa ngokweqile, shayela ucingo losizo lokulawula ubuthi ku-1-800-222-1222. Imininingwane iyatholakala online ku-https: //www.poisonhelp.org/help. Uma isisulu siwile, saba nokuquleka, sinenkinga yokuphefumula, noma singakwazi ukuvuswa, shayela ngokushesha abezimo eziphuthumayo ku-911.

Izimpawu zokudlula ngokweqile zingafaka okulandelayo:

• ubuhlungu bamathambo
• ukuvuvukala
• ukuphelelwa umoya

Gcina wonke ama-aphoyintimenti nodokotela wakho kanye nelabhorethri. Udokotela wakho uzo-oda izivivinyo ezithile zelebhu ukuze ahlole impendulo yomzimba wakho kumkhiqizo womjovo we-pegfilgrastim.

Ngaphambi kokwenza ucwaningo lwamathambo, tshela udokotela wakho nochwepheshe ukuthi usebenzisa umkhiqizo womjovo we-pegfilgrastim. I-Pegfilgrastim ingathinta imiphumela yalolu hlobo lokutadisha.

Ungavumeli omunye umuntu ukuthi athathe imithi yakho. Buza usokhemisi wakho noma imiphi imibuzo onayo mayelana nokugcwalisa umuthi wakho.

Kubalulekile ukuthi ugcine uhlu olubhaliwe lwayo yonke imishanguzo oyisebenzisayo kadokotela kanye nokungabhaliswanga (ngaphezulu kokuthenga), kanye nanoma yimiphi imikhiqizo efana namavithamini, amaminerali, noma ezinye izithako zokudla.Kufanele uze nalolu hlu njalo uma uvakashela udokotela noma uma ungeniswa esibhedlela. Kubaluleke kakhulu futhi nemininingwane ebalulekile ukuthi uphathe uma kwenzeka kunezimo eziphuthumayo.

• UFulphila^®(i-pegfilgrastim-jmdb)
• I-Neulasta^®(i-pegfilgrastim)
• Udenyca^®(i-pegfilgrastim-cbqv)
• I-Ziextenzo (pegfilgrastim-bmez)