Umjovo we-Decitabine

-Delile

• Ngaphambi kokuthola umthamo we-decitabine,
• I-Decitabine ingadala imiphumela emibi. Tshela udokotela wakho uma kukhona kulezi zimpawu ezinzima noma ezingapheli:
• Eminye imiphumela emibi ingaba mibi. Uma uhlangabezana nenye yalezi zimpawu, shayela udokotela wakho ngokushesha:
• Shayela udokotela wakho ngokushesha uma unanoma iyiphi yalezi zimpawu ezilandelayo ze-hyperglycemia (ushukela ophakeme wegazi):
• Izimpawu zokudlula ngokweqile zingafaka:

I-Decitabine isetshenziselwa ukwelapha i-myelodysplastic syndrome (iqembu lezimo lapho umnkantsha wethambo ukhiqiza khona amangqamuzana egazi angafakwanga kahle futhi angavezi amaseli wegazi anele). I-Decitabine isekilasini lemithi ebizwa ngama-hypomethylation agents. Isebenza ngokusiza umnkantsha wethambo ukukhiqiza amangqamuzana egazi ajwayelekile nangokubulala amaseli angajwayelekile emnkantsheni wethambo.

IDecitabine iza njengempuphu ezokwengezwa oketshezini futhi ijovwe kancane ngaphezulu kwamahora ama-3 ngemithambo (emthanjeni) ngudokotela noma umhlengikazi ehhovisi lezokwelapha noma emtholampilo wabangalaliswa esibhedlela. Imvamisa ijovwa njalo emahoreni ayisishiyagalombili izinsuku ezintathu. Le nkathi yokwelashwa ibizwa ngokuthi umjikelezo, futhi umjikelezo ungaphindaphindwa njalo emavikini ayisithupha isikhathi eside nje uma udokotela wakho encoma. I-Decitabine kufanele inikezwe okungenani imijikelezo emine kepha ingaqhubeka uma udokotela wakho enquma ukuthi uzozuza ekwelashweni okwengeziwe.

Udokotela wakho futhi angadinga ukubambezela ukwelashwa kwakho futhi anciphise umthamo wakho uma uhlangabezana nemiphumela ethile emibi. Qiniseka ukuthi utshela udokotela wakho ukuthi uzizwa kanjani ngesikhathi sokwelashwa kwakho nge-decitabine.

Udokotela wakho uzokunika imithi yokuvikela isicanucanu nokuhlanza ngaphambi kokuthola umthamo ngamunye we-decitabine.

Lo muthi ungabekelwa okunye ukusetshenziswa; buza udokotela wakho noma usokhemisi ukuthola eminye imininingwane.

Ngaphambi kokuthola umthamo we-decitabine,

• Tshela udokotela wakho kanye nosokhemisi uma unegciwane ku-decitabine noma eminye imithi.
• Tshela udokotela wakho kanye nosokhemisi ukuthi imiphi imishanguzo kadokotela neyokungabhalisi, amavithamini, izithako zokudla okunempilo, nemikhiqizo yamakhambi oyithathayo noma ohlela ukuyithatha. Udokotela wakho angadinga ukushintsha imithamo yemithi yakho noma akuqaphele ngokucophelela ngemiphumela emibi.
• tshela udokotela wakho uma unesifo sezinso noma sesibindi.
• tshela udokotela wakho uma ukhulelwe noma uhlela ukukhulelwa, noma uma uhlela ukuba nobaba wengane. Wena noma umlingani wakho akufanele ukhulelwe ngenkathi usebenzisa i-decitabine. Kufanele usebenzise ukulawulwa kokubeletha ukuvimbela ukukhulelwa kuwe noma kumlingani wakho ngesikhathi sokwelashwa kwakho nge-decitabine nangezinyanga ezimbili ngemuva kwalokho. Khuluma nodokotela wakho ngezindlela zokulawula ukubeletha ezizokusebenzela. Uma wena noma umlingani wakho ukhulelwa ngenkathi usebenzisa i-decitabine, shayela udokotela wakho. I-Decitabine ingalimaza umbungu.
• tshela udokotela wakho uma uncelisa.

Ngaphandle kokuthi udokotela wakho akutshele ngenye indlela, qhubeka nokudla okuvamile.

Shayela udokotela wakho ngokushesha uma ungakwazi ukugcina i-aphoyintimenti yokuthola umthamo we-decitabine.

I-Decitabine ingadala imiphumela emibi. Tshela udokotela wakho uma kukhona kulezi zimpawu ezinzima noma ezingapheli:

• ukukhathala ngokweqile
• isikhumba esiphaphathekile
• ikhanda
• isiyezi
• ukudideka
• ukushaya kwenhliziyo okusheshayo
• ubunzima bokulala noma ukulala
• ubuthakathaka
• ukuphelelwa umoya
• isicanucanu
• ukuqunjelwa
• isifo sohudo
• ukuhlanza
• ubuhlungu besisu
• isilungulela noma isisu
• izilonda ezibuhlungu emlonyeni, noma olimini noma ezindebeni
• amabala abomvu esikhunjeni
• ukuqubuka
• ushintsho kumbala wesikhumba
• ukulahleka kwezinwele
• ubuhlungu obuhlangene noma besisipha
• ukungaphatheki kahle kwesifuba noma ubuhlungu besifuba
• ukuvuvukala kwezandla, izinyawo, amaqakala, imilenze ephansi, noma isisu
• ubuhlungu, ukuvuvukala, noma ubomvu endaweni yomjovo

Eminye imiphumela emibi ingaba mibi. Uma uhlangabezana nenye yalezi zimpawu, shayela udokotela wakho ngokushesha:

• ukopha okungajwayelekile noma ukulinyazwa
• isifuba
• ukulunywa
• ukuphefumula kanzima noma ukugwinya
• ukuvuvukala kobuso
• umphimbo obuhlungu, umkhuhlane, amakhaza, ukukhwehlela, noma ezinye izimpawu zokutheleleka

Shayela udokotela wakho ngokushesha uma unanoma iyiphi yalezi zimpawu ezilandelayo ze-hyperglycemia (ushukela ophakeme wegazi):

• ukoma ngokweqile
• ukuchama kaningi
• indlala eyeqile
• ubuthakathaka
• ukungaboni kahle

I-Decitabine ingadala eminye imiphumela emibi. Shayela udokotela wakho uma unezinkinga ezingavamile ngenkathi uthola lo muthi.

Uma uthola imiphumela emibi kakhulu, wena noma udokotela wakho ungathumela umbiko kuhlelo lwe-Food and Drug Administration's (FDA) MedWatch Adverse Event Reporting online (http://www.fda.gov/Safety/MedWatch) noma ngocingo ( 1-800-332-1088).

Uma kwenzeka ukweqisa ngokweqile, shayela ucingo losizo lokulawula ubuthi ku-1-800-222-1222. Imininingwane iyatholakala online ku-https: //www.poisonhelp.org/help. Uma isisulu siwile, saba nokuquleka, sinenkinga yokuphefumula, noma singakwazi ukuvuswa, shayela ngokushesha abezimo eziphuthumayo ku-911.

Izimpawu zokudlula ngokweqile zingafaka:

• ukopha okungajwayelekile noma ukulinyazwa
• umphimbo obuhlungu, umkhuhlane, amakhaza, ukukhwehlela, noma ezinye izimpawu zokutheleleka

Gcina wonke ama-aphoyintimenti nodokotela wakho kanye nelabhorethri. Udokotela wakho uzo-oda izivivinyo ezithile zelebhu ukuze ahlole impendulo yomzimba wakho ku-decitabine.

Kubalulekile ukuthi ugcine uhlu olubhaliwe lwayo yonke imishanguzo oyisebenzisayo kadokotela kanye nokungabhaliswanga (ngaphezulu kokuthenga), kanye nanoma yimiphi imikhiqizo efana namavithamini, amaminerali, noma ezinye izithako zokudla. Kufanele uze nalolu hlu njalo uma uvakashela udokotela noma uma ungeniswa esibhedlela. Kubaluleke kakhulu futhi nemininingwane ebalulekile ukuthi uphathe uma kwenzeka kunezimo eziphuthumayo.

• UDacogen^®