I-Tretinoin

-Delile

• Ngaphambi kokuthatha i-tretinoin,
• I-Tretinoin ingadala imiphumela emibi. Tshela udokotela wakho uma kukhona kulezi zimpawu ezinzima noma ezingapheli:
• Eminye imiphumela emibi ingaba mibi. Uma uhlangabezana nenye yalezi zimpawu noma lezo ezibalwe esigabeni ESIBALULEKILE SESEXWAYISO, shayela udokotela wakho ngokushesha:
• Izimpawu zokudlula ngokweqile zingafaka:

I-Tretinoin ingadala imiphumela emibi kakhulu. I-Tretinoin kufanele inikezwe kuphela ngaphansi kokuqondisa kukadokotela onolwazi lokwelapha abantu abane-leukemia (umdlavuza wamaseli amhlophe egazi) nasesibhedlela lapho iziguli zingabhekwa khona ngemiphumela emibi kakhulu futhi ziphathwe uma kwenzeka le miphumela emibi.

I-Tretinoin ingadala iqembu lezimpawu ezibucayi noma ezisongela ukuphila elibizwa nge-retinoic acid-APL (RA-APL) syndrome. Udokotela wakho uzokuqapha ngokucophelela ukuze abone ukuthi uyayihlakulela yini le syndrome. Uma uhlangabezana nalezi zimpawu ezilandelayo, shayela udokotela wakho ngokushesha: umkhuhlane; ukukhuluphala; ukuvuvukala kwezingalo, izandla, izinyawo, amaqakala, noma imilenze engezansi; ukuphelelwa umoya; ukuphefumula kanzima ukushaya; ubuhlungu besifuba; noma ukukhwehlela. Esibonakalisweni sokuqala sokuthi uthuthukisa i-RA-APL syndrome, udokotela wakho uzokunikeza umuthi owodwa noma ngaphezulu yokwelapha lesi sifo.

I-Tretinoin ingadala ukwanda okusheshayo kwenani lamaseli amhlophe egazi emzimbeni. Lokhu kuhlotshaniswa nengozi ephezulu yemiphumela esongela impilo. Uma unenani eliphakeme kakhulu lamaseli amhlophe egazi ngaphambi kokuqala ukwelashwa kwe-tretinoin, noma uma unokwanda kwenani lamaseli amhlophe egazi ngenkathi welashwa nge-tretinoin, ikakhulukazi uma uhlangabezana nezimpawu zesifo se-RA-APL, udokotela wakho angakunikeza umuthi owodwa noma ngaphezulu ukwelapha noma ukuvimbela ukwanda kwamaseli amhlophe egazi.

Gcina wonke ama-aphoyintimenti nodokotela wakho kanye nelabhorethri. Udokotela wakho uzo-oda izivivinyo ezithile ukuze ahlole impendulo yomzimba wakho ku-tretinoin.

Khuluma nodokotela wakho ngengozi (s) yokuthatha i-tretinoin.

Ezigulini zesifazane:

I-Tretinoin akufanele ithathwe yiziguli ezikhulelwe noma ezingakhulelwa. Kukhona ingozi enkulu yokuthi i-tretinoin izodala ukuthi ingane izalwe inokukhubazeka kokuzalwa (izinkinga zomzimba ezikhona lapho kuzalwa).

Uma ungakhulelwa, kuzodingeka ugweme ukukhulelwa ngesikhathi sokwelashwa kwakho nge-tretinoin. Kufanele usebenzise izindlela ezimbili ezamukelekayo zokulawulwa kokubeletha ngesikhathi sokwelashwa kwakho nenyanga e-1 ngemuva kokwelashwa kwakho, noma ngabe unenkinga yokuzala (unenkinga yokukhulelwa) noma uke waba nokunqamuka kokuya esikhathini ('ushintsho lwempilo'; ukuphela kwezikhathi zokuya esikhathini njalo ngenyanga).Kufanele usebenzise lezi zinhlobo ezimbili zokulawula ukubeletha ngaso sonke isikhathi ngaphandle kokuthi ungathembisa ukuthi ngeke ube nokuxhumana ngokocansi nowesilisa inyanga eyodwa ngemuva kokwelashwa kwakho. Udokotela wakho uzokutshela ukuthi iziphi izindlela zokulawula ukubeletha ezamukelekayo, futhi uzokunikeza imininingwane ephelele mayelana nokulawulwa kokuzalwa.

Uma uhlela ukusebenzisa izinto zokuvimbela inzalo zomlomo (amaphilisi okulawula ukubeletha) ngenkathi uthatha i-tretinoin, tshela udokotela wakho igama lephilisi ozolisebenzisa. I-Microdosed progestin ('minipill') yokuvimbela inzalo yomlomo (i-Ovrette, iMicronor, iNor-D) ingahle ingabi yindlela ephumelelayo yokulawulwa kokuzalwa kwabantu abathatha i-tretinoin.

Kufanele ube nokuhlolwa kokukhulelwa okungekuhle kungakapheli isonto eli-1 ngaphambi kokuba uqale ukuthatha i-tretinoin. Uzodinga futhi nokuhlolelwa ukukhulelwa elabhorethri inyanga nenyanga ngesikhathi sokwelashwa kwakho. Tshela udokotela wakho ngokushesha uma ucabanga ukuthi ungakhulelwa nganoma yisiphi isikhathi ngesikhathi sokwelashwa kwakho nge-tretinoin.

I-Tretinoin isetshenziselwa ukwelapha i-acute promyelocytic leukemia (APL; uhlobo lomdlavuza lapho kunamaseli egazi amaningi angavuthwa kakhulu egazini nasemnkantsheni wethambo) kubantu abangasizwanga ezinye izinhlobo zamakhemikhali noma isimo sabo esithuthukile kodwa kwanda kulandela ukwelashwa nezinye izinhlobo zamakhemikhali. I-Tretinoin isetshenziselwa ukukhiqiza ukuxolelwa (ukwehla noma ukunyamalala kwezimpawu nezimpawu zomdlavuza) we-APL, kepha eminye imishanguzo kufanele isetshenziswe ngemuva kokwelashwa nge-tretinoin ukuvimbela umdlavuza ukuthi ungabuyi. UTretinoin usesigabeni semithi ebizwa ngama-retinoids. Isebenza ngokunciphisa noma ngokumisa ukukhula kwamangqamuzana omdlavuza ngokubangela amangqamuzana egazi angavuthiwe ukuba akhule abe ngamaseli egazi ajwayelekile.

I-Tretinoin iza njenge-capsule ezothathwa ngomlomo. Imvamisa kuthathwa kabili ngosuku kuze kube yizinsuku ezingama-90. Thatha i-tretinoin ngasikhathi sinye nsuku zonke. Landela izinkomba ezikulebuli kadokotela wakho ngokucophelela, bese ubuza udokotela noma usokhemisi wakho ukuthi akuchaze nganoma iyiphi ingxenye ongayiqondi. Thatha i-tretinoin njengoba iqondisiwe. Ungayithathi kancane noma uyithathe kaningi kunokuyalelwa ngudokotela wakho.

Qhubeka uthathe i-tretinoin noma ngabe uzizwa uphilile. Ungayeki ukuthatha i-tretinoin ngaphandle kokukhuluma nodokotela wakho.

Lo muthi ungabekelwa okunye ukusetshenziswa; buza udokotela wakho noma usokhemisi ukuthola eminye imininingwane.

Ngaphambi kokuthatha i-tretinoin,

• Tshela udokotela wakho kanye nosokhemisi uma une-allergies ku-tretinoin, amanye ama-retinoid anjenge-acitretin (Soriatane), etretinate (Tegison), bexarotene, noma i-isotretinoin (i-Accutane, i-Claravis, i-Sotret), noma imiphi eminye imithi, i-parabens (i-preservative), noma iyiphi ezinye izithako kuma-capsule we-tretinoin. Buza udokotela wakho noma usokhemisi uhlu lwezithako.
• Tshela udokotela wakho kanye nosokhemisi ukuthi imiphi imishanguzo kadokotela neyokungabhalisi, amavithamini, izithako zokudla okunempilo, nemikhiqizo yamakhambi oyithathayo noma ohlela ukuyithatha. Qiniseka ukuthi usho noma yikuphi okulandelayo: i-aminocaproic acid (Amicar); ezinye izivimbeli zesiteshi se-calcium ezifana ne-diltiazem (Cardizem, Dilacor, Tiazac, abanye) kanye ne-verapamil (Calan, Covera, Isoptin, Verelan); i-cimetidine (Tagamet); i-cyclosporine (iSandimmune, iGengraf, Neoral); i-erythromycin (E.E.S., Erythrocin, E-Mycin); i-hydroxyurea (iDroxia); ketoconazole (Nizoral); pentobarbital; i-phenobarbital; i-rifampin (i-Rifadin, i-Rimactane); i-steroids yomlomo efana ne-dexamethasone (i-Decadron, i-Dexone), i-methylprednisolone (i-Medrol) ne-prednisone (i-Deltasone); ama-antibiotic e-tetracycline njenge-demeclocycline (i-Declomycin), i-doxycycline (i-Monodox, i-Vibramycin, abanye), i-minocycline (i-Minocin), i-oxytetracycline (i-Terramycin), ne-tetracycline (i-Sumycin, i-Tetrex, abanye); i-tranexamic acid (iCyklokapron); novithamini A. Udokotela wakho angadinga ukushintsha imithamo yemithi yakho noma akuqaphele ngokucophelela ngemiphumela emibi. Eminye imishanguzo eminingi ingaxhumana ne-tretinoin, ngakho-ke qiniseka ukuthi utshela udokotela wakho ngayo yonke imithi oyiphuzayo, ngisho nalawo angaveli kulolu hlu.
• Tshela udokotela wakho uma ngabe uke wakwazi ukwanda noma ungakanani isibalo se-cholesterol (into efana namafutha) nezinye izinto ezinamafutha egazini, noma isibindi noma isifo senhliziyo.
• tshela udokotela wakho uma uncelisa.
• uma uzohlinzwa, kufaka phakathi ukuhlinzwa kwamazinyo, tshela udokotela noma udokotela wamazinyo ukuthi uthatha i-tretinoin.
• Kufanele wazi ukuthi i-tretinoin ingadala isiyezi noma ikhanda elibuhlungu.Ungashayeli imoto noma usebenzise imishini uze wazi ukuthi lo muthi ukuthinta kanjani.

Khuluma nodokotela wakho mayelana nokudla isithelo samagilebhisi nokuphuza ijusi lamagilebhisi ngenkathi uthatha lo muthi.

Thatha umthamo ongabanjwanga ngokushesha nje lapho uwukhumbula. Kodwa-ke, uma sekuyisikhathi somthamo olandelayo, weqa umthamo ongabanjwanga bese uqhubeka neshejuli yakho ejwayelekile yokulinganisa. Ungathathi umthamo ophindwe kabili ukwenza okulahlekile.

I-Tretinoin ingadala imiphumela emibi. Tshela udokotela wakho uma kukhona kulezi zimpawu ezinzima noma ezingapheli:

• ubuthakathaka
• ukukhathala ngokweqile
• ngiqhaqhazela
• ubuhlungu
• indlebe
• umuzwa wokugcwala ezindlebeni
• isikhumba esomile
• ukuqubuka
• ukulahleka kwezinwele
• ukuqunjelwa
• isifo sohudo
• ubuhlungu besisu
• isilungulela
• ukulahlekelwa isifiso sokudla
• ukuncipha komzimba
• ubuhlungu bamathambo
• isiyezi
• ukuba ndikindiki, ukushiswa, noma ukuncinza ezandleni noma ezinyaweni
• uvalo
• ukudana
• ubunzima bokulala noma ukulala
• ukudideka
• ukuyaluza
• ukubona izinto ezingekho (ukubona izinto noma ukuzwa amazwi angekho)
• ubunzima bokuchama
• ukuqhuma

Eminye imiphumela emibi ingaba mibi. Uma uhlangabezana nenye yalezi zimpawu noma lezo ezibalwe esigabeni ESIBALULEKILE SESEXWAYISO, shayela udokotela wakho ngokushesha:

• ikhanda
• isicanucanu
• ukuhlanza
• ukufiphala noma umbono ophindwe kabili, noma ezinye izinkinga zombono
• ukulimaza noma ukopha okungavamile
• uhlanza olunegazi noma olubukeka njengezizathu zekhofi
• izitulo ezibomvu ngokukhanyayo noma ezimnyama nezokulinda
• ukushaya kwenhliziyo okungajwayelekile
• ukulahlekelwa ukuzwa
• ukopha
• izifo

I-Tretinoin ingakhuphula amazinga e-cholesterol namanye amafutha egazini lakho futhi ingamisa isibindi sakho ekusebenzeni ngokujwayelekile. Udokotela wakho uzokuqapha ngokucophelela ukuze abone ukuthi ngabe uhlangabezana yini neminye yale miphumela emibi.

I-Tretinoin ingadala eminye imiphumela emibi. Shayela udokotela wakho uma unezinkinga ezingavamile ngenkathi uthatha lo muthi.

Uma uthola imiphumela emibi kakhulu, wena noma udokotela wakho ungathumela umbiko kuhlelo lwe-Food and Drug Administration's (FDA) MedWatch Adverse Event Reporting online (http://www.fda.gov/Safety/MedWatch) noma ngocingo ( 1-800-332-1088).

Gcina le mithi esitsheni efike ngayo, ivalwe ngokuqinile, futhi lapho izingane zingafinyeleleki khona. Gcina ekamelweni lokushisa kude nokushisa okweqile nomswakama (hhayi endlini yangasese).

Imithi engadingeki kufanele ilahlwe ngezindlela ezikhethekile zokuqinisekisa ukuthi izilwane ezifuywayo, izingane nabanye abantu abakwazi ukuzidla. Kodwa-ke, akufanele ukhiphe le mithi ethoyilethi. Esikhundleni salokho, indlela engcono kakhulu yokulahla imithi yakho ngohlelo lokubuyisa umuthi. Khuluma nosokhemisi wakho noma uthinte umnyango wangakini wokulahla udoti / wokusebenzisa kabusha ukuze ufunde ngezinhlelo zokubuyisa emphakathini wakho. Bheka iwebhusayithi yakwa-FDA's Safe Disposal of Medicines (http://goo.gl/c4Rm4p) ukuthola eminye imininingwane uma ungakwazi ukufinyelela kuhlelo lokubuyisa.

Kubalulekile ukugcina yonke imishanguzo ingabonakali futhi ifinyeleleke ezinganeni njengoba iziqukathi eziningi (njengezingqondo zamaphilisi zamasonto onke kanye nalawo amaconsi wamehlo, okhilimu, amabala, kanye nama-inhalers) azimeleki ezinganeni futhi izingane ezincane zingazivula kalula. Ukuvikela izingane ezisencane ekufakeni ubuthi, hlala uvala amakepisi okuphepha bese ubeka umuthi endaweni ephephile - eyodwa ephezulu futhi engekho futhi engabonakali kubo futhi efinyelela kuyo. http://www.upandaway.org

Uma kwenzeka ukweqisa ngokweqile, shayela ucingo losizo lokulawula ubuthi ku-1-800-222-1222. Imininingwane iyatholakala online ku-https: //www.poisonhelp.org/help. Uma isisulu siwile, saba nokuquleka, sinenkinga yokuphefumula, noma singakwazi ukuvuswa, shayela ngokushesha abezimo eziphuthumayo ku-911.

Izimpawu zokudlula ngokweqile zingafaka:

• ikhanda
• ukuqhuma
• izindebe ezibomvu, eziqhekekile nezibuhlungu
• ubuhlungu besisu
• isiyezi
• ukulahleka kokuxhumanisa

Ungavumeli omunye umuntu ukuthi athathe imithi yakho. Buza usokhemisi wakho uma unemibuzo mayelana nokugcwalisa imishanguzo yakho.

Kubalulekile ukuthi ugcine uhlu olubhaliwe lwayo yonke imishanguzo oyisebenzisayo kadokotela kanye nokungabhaliswanga (ngaphezulu kokuthenga), kanye nanoma yimiphi imikhiqizo efana namavithamini, amaminerali, noma ezinye izithako zokudla. Kufanele uze nalolu hlu njalo uma uvakashela udokotela noma uma ungeniswa esibhedlela. Kubaluleke kakhulu futhi nemininingwane ebalulekile ukuthi uphathe uma kwenzeka kunezimo eziphuthumayo.

• Vesanoid^®