Inaliti yeLevoleucovorin

-Delile

• Ngaphambi kokuthola umjovo we-levoleucovorin,
• Umjovo weLevoleucovorin kanye nemithi enikezwa ngayo ingadala imiphumela emibi. Tshela udokotela wakho uma kukhona kulezi zimpawu ezinzima noma ezingapheli:
• Eminye imiphumela emibi ingaba mibi. Uma uhlangabezana nanoma yiziphi zalezi zimpawu noma lezo esigabeni esikhethekile SOKUQAPHA, shayela udokotela wakho ngokushesha noma uthole ukwelashwa okuphuthumayo:

Umjovo weLevoleucovorin usetshenziswa kubantu abadala nasezinganeni ukuvimbela imiphumela eyingozi ye-methotrexate (Trexall) lapho i-methotrexate isetshenziselwa ukwelapha i-osteosarcoma (umdlavuza owakhiwa emathanjeni). Umjovo weLevoleucovorin nawo usetshenziselwa ukwelapha abantu abadala nezingane abathole ngokweqile i-methotrexate noma imishanguzo efanayo noma abangakwazi ukuqeda le mithi kahle emizimbeni yabo. Umjovo weLevoleucovorin ubuye usetshenziswe ne-fluorouracil (5-FU, umuthi wokwelapha ngamakhemikhali) ukwelapha abantu abadala abanomdlavuza obala (umdlavuza oqala emathunjini amakhulu) osabalele kwezinye izingxenye zomzimba. Umjovo weLevoleucovorin usesigabeni semithi ebizwa nge-folic acid analogs. Isebenza ukuvimbela imiphumela eyingozi ye-methotrexate ngokuvikela amaseli anempilo, ngenkathi ivumela i-methotrexate ukuthi ingene futhi ibulale amangqamuzana omdlavuza.Isebenza ukwelapha umdlavuza obala ngokhulisa imiphumela ye-fluorouracil.

Umjovo weLevoleucovorin uza njengesisombululo (uketshezi) nanjengempuphu ezoxutshwa noketshezi bese ujovwa ngomjovo (emthanjeni) ngudokotela noma umhlengikazi esibhedlela noma ehhovisi lezokwelapha. Lapho i-levoleucovorin isetshenziselwa ukuvimbela imiphumela eyingozi ye-methotrexate noma ukwelapha ukweqisa izidakamizwa kwe-methotrexate, ivame ukunikezwa njalo emahoreni ayisithupha, kuqala amahora angama-24 ngemuva komthamo we-methotrexate noma ngokushesha okukhulu ngemuva kokudlula ngokweqile nokuqhubeka kuze kube ukuhlolwa kwe-laboratory kukhombisa ukuthi akusadingeki. Lapho umjovo we-levoleucovorin usetshenziselwa ukwelapha umdlavuza obala ngokombala, uvame ukunikezwa kanye ngosuku izinsuku eziyisi-5 zilandelana njengengxenye yomjikelezo wokulinganisa ongaphindwa njalo emavikini amane kuya kwayi-5.

Lo muthi ungabekelwa okunye ukusetshenziswa; buza udokotela wakho noma usokhemisi ukuthola eminye imininingwane.

Ngaphambi kokuthola umjovo we-levoleucovorin,

• Tshela udokotela kanye nosokhemisi wakho uma uneguliswa umjovo we-levoleucovorin, i-leucovorin, i-folic acid (i-Folicet, kuma-multivitamini), i-folinic acid, noma yimuphi omunye umuthi.
• Tshela udokotela wakho kanye nosokhemisi ukuthi imiphi eminye imishanguzo kadokotela neyokungabhalisi, amavithamini, izithasiselo zokudla okunempilo, nemikhiqizo yamakhambi oyithathayo noma ohlela ukuyithatha. Qinisekisa ukusho noma yikuphi kokulandelayo: phenobarbital, phenytoin (Dilantin), primidone (Mysoline), noma i-trimethoprim-sulfamethoxazole (Bactrim, Septra). Udokotela wakho angadinga ukushintsha imithamo yemithi yakho noma akuqaphele ngokucophelela ngemiphumela emibi.
• udokotela wakho angakunika umjovo we-levoleucovorin nge-fluorouracil. Uma uthola le nhlanganisela yemithi, uzobhekwa ngokucophelela ngoba i-levoleucovorin ingakhuphula izinzuzo nemiphumela emibi ye-fluorouracil. Uma uhlangabezana nanoma yiziphi kulezi zimpawu ezilandelayo, shayela udokotela wakho ngokushesha: uhudo olunzima, ubuhlungu besisu noma ukuqunjelwa, ukoma okwandayo, ukuncipha kokuchama, noma ubuthakathaka obukhulu,
• Tshela udokotela wakho uma unomlomo owomile, umchamo omnyama, ukujuluka okunciphile, isikhumba esomile, nezinye izimpawu zokwehla kwamanzi emzimbeni futhi uma ngabe uke waba nomswakama omningi esifubeni noma esiswini noma isifo sezinso.
• utshele udokotela wakho uma ukhulelwe, hlela ukukhulelwa, noma uncelisa. Uma ukhulelwa ngenkathi uthola umjovo we-levoleucovorin, shayela udokotela wakho.

Ngaphandle kokuthi udokotela wakho akutshele ngenye indlela, qhubeka nokudla okuvamile.

Umjovo weLevoleucovorin kanye nemithi enikezwa ngayo ingadala imiphumela emibi. Tshela udokotela wakho uma kukhona kulezi zimpawu ezinzima noma ezingapheli:

• izilonda zomlomo
• isicanucanu
• ukuhlanza
• ukulahlekelwa isifiso sokudla
• ubuhlungu besisu
• isifo sohudo
• isilungulela
• ukudideka
• ukuba ndikindiki, ukushiswa, noma ukuncinza ezandleni noma ezinyaweni
• izinguquko kwikhono lokunambitha ukudla
• ukulahleka kwezinwele
• ukuluma noma isikhumba esomile
• ukukhathala

Eminye imiphumela emibi ingaba mibi. Uma uhlangabezana nanoma yiziphi zalezi zimpawu noma lezo esigabeni esikhethekile SOKUQAPHA, shayela udokotela wakho ngokushesha noma uthole ukwelashwa okuphuthumayo:

• ukuphefumula kanzima
• ukulunywa
• ukuqubuka
• imfiva
• Ukugodola

Umjovo weLevoleucovorin ungadala eminye imiphumela emibi. Shayela udokotela wakho uma unezinkinga ezingavamile ngenkathi uthola lo muthi.

Uma uthola imiphumela emibi kakhulu, wena noma udokotela wakho ungathumela umbiko kuhlelo lwe-Food and Drug Administration's (FDA) MedWatch Adverse Event Reporting online (http://www.fda.gov/Safety/MedWatch) noma ngocingo ( 1-800-332-1088).

Uma kwenzeka ukweqisa ngokweqile, shayela ucingo losizo lokulawula ubuthi ku-1-800-222-1222. Imininingwane iyatholakala online ku-https: //www.poisonhelp.org/help. Uma isisulu siwile, saba nokuquleka, sinenkinga yokuphefumula, noma singakwazi ukuvuswa, shayela ngokushesha abezimo eziphuthumayo ku-911.

Gcina wonke ama-aphoyintimenti nodokotela wakho kanye nelabhorethri. Udokotela wakho uzo-oda izivivinyo ezithile zelebhu ukuze ahlole impendulo yomzimba wakho kumjovo we-levoleucovorin.

Kubalulekile ukuthi ugcine uhlu olubhaliwe lwayo yonke imishanguzo oyisebenzisayo kadokotela kanye nokungabhaliswanga (ngaphezulu kokuthenga), kanye nanoma yimiphi imikhiqizo efana namavithamini, amaminerali, noma ezinye izithako zokudla. Kufanele uze nalolu hlu njalo uma uvakashela udokotela noma uma ungeniswa esibhedlela. Kubaluleke kakhulu futhi nemininingwane ebalulekile ukuthi uphathe uma kwenzeka kunezimo eziphuthumayo.

• Fusilev^®
• Khapzory^®