Inaliti ye-Methylnaltrexone

-Delile

• Ngaphambi kokusebenzisa umjovo we-methylnaltrexone,
• Umjovo weMethylnaltrexone ungadala imiphumela emibi. Tshela udokotela wakho uma kukhona kulezi zimpawu ezinzima noma ezingapheli:
• Eminye imiphumela emibi ingaba mibi. Uma uhlangabezana nalesi sibonakaliso, yeka ukusebenzisa i-methylnaltrexone bese ushayela udokotela wakho ngokushesha:
• Izimpawu zokudlula ngokweqile zingafaka okulandelayo:

Umjovo weMethylnaltrexone usetshenziselwa ukwelapha ukuqunjelwa okubangelwa yimithi yezinhlungu ye-opioid (narcotic) kubantu abanezinhlungu ezingapheli (eziqhubekayo) ezingabangelwa ngumdlavuza kepha kungenzeka zihlobene nomdlavuza wangaphambilini noma ukwelashwa komdlavuza. Ibuye isetshenziselwe ukwelapha ukuqunjelwa okubangelwa yimithi yezinhlungu ze-opioid kubantu abanesifo esithuthukile noma izinhlungu zomdlavuza ezisebenzayo. Umjovo weMethylnaltrexone usekilasini lemithi ebizwa ngokuthi yi-peripherally acting mu-opioid receptor antagonists. Isebenza ngokuvikela amathumbu emiphumeleni yemithi ye-opioid (narcotic).

Umjovo weMethylnaltrexone uza njengesisombululo (uketshezi) ukujova ngomgogodla (ngaphansi kwesikhumba). Uma isetshenziselwa ukwelapha ukuqunjelwa okubangelwa yimithi ye-opioid kubantu abanezinhlungu ezingapheli (eziqhubekayo) ezingabangelwa umdlavuza, kuvamise ukujova kanye ngosuku. Uma isetshenziselwa ukwelashwa ukuqunjelwa okubangelwa yimithi ye-opioid kubantu abanesifo esithuthukile noma umdlavuza, kuvamise ukujova kanye njalo ngosuku njengoba kudingeka, kepha ingasetshenziswa kuze kube kanye njalo emahoreni angama-24 uma kudingeka. Landela izinkomba ezikulebuli kadokotela wakho ngokucophelela, bese ubuza udokotela noma usokhemisi wakho ukuthi akuchaze nganoma iyiphi ingxenye ongayiqondi. Sebenzisa umjovo we-methylnaltrexone njengoba nje uqondisiwe. Ungayisebenzisi ngaphezulu noma ngaphansi kwayo noma uyisebenzise kaningi kunokuyalelwa ngudokotela wakho.

Umjovo weMethylnaltrexone uzosetshenziswa ngabantu abathatha imishanguzo ye-opioid (narcotic). Khuluma nodokotela wakho uma ushintsha ukuthi uthatha imishanguzo yama-opioid kangakanani noma kangaki. Uma uyeka ukuthatha imishanguzo ye-opioid, kufanele futhi uyeke ukusebenzisa umjovo we-methylnaltrexone.

Kufanele uyeke ukuthatha eminye imithi ye-laxative lapho uqala ukusebenzisa umjovo we-methylnaltrexone. Kodwa-ke, qiniseka ukwazisa udokotela wakho uma umjovo we-methylnaltrexone ungakusebenzeli ngemuva kokuwusebenzisa izinsuku ezintathu. Udokotela wakho angakutshela ukuthi uthathe eminye imithi yokwelapha i-laxative.

Ungazijova ngokwakho umjovo we-methylnaltrexone noma umngane noma isihlobo senze imijovo. Funda ngokucophelela imiyalelo yomkhiqizi echaza ukuthi ungalungiselela kanjani futhi ujove umthamo we-methylnaltrexone. Buza udokotela wakho noma usokhemisi ukuthi akubonise noma umuntu ozobe ejova umuthi ukuthi ungawujova kanjani. Qiniseka ukuthi ubuza usokhemisi noma udokotela wakho uma unanoma yimiphi imibuzo mayelana nokuthi ungayilungisa kanjani noma uyijove kanjani le mithi.

Umjovo weMethylnaltrexone ufika ngemijovo ekhethiwe nakumabhodlela okuzosetshenziswa ngamasirinji alahlwayo. Isitsha singafika kuthileyi onomjovo, noma ungadinga ukuthenga imijovo ngokwehlukana. Buza udokotela noma usokhemisi wakho uma unemibuzo ngohlobo lwamajojo ongawasebenzisa. Sebenzisa imijovo enamanzi, izigaxa kanye nemijovo elahlwayo kanye kuphela. Lahla umjovo owuthandayo, noma i-vial ne-syringe ngemuva kokusebenzisa kanye, noma kungenalutho. Kufanele zilahlwe esitsheni esingamelana nokubhoboza, lapho izingane zingakwazi ukufinyelela kuzo. Ungalahli isitsha esigcwele ukumelana nokubhoboza kudoti wasekhaya noma uvuselelwe kabusha. Khuluma nodokotela wakho noma usokhemisi mayelana nokuthi ungasilahla kanjani isitsha esimelana nokubhoboza.

Ungajova i-methylnaltrexone ngaphansi kwesikhumba esiswini noma emathangeni akho. Uma omunye umuntu ezokujolela umuthi, lowo muntu angawufaka engalweni yakho engenhla. Khetha indawo entsha njalo lapho usebenzisa umjovo we-methylnaltrexone. Ungafaki i-methylnaltrexone endaweni ethambile, elimele, ebomvu noma eqinile. Futhi, musa ukujova ezindaweni ezinezibazi noma izimpawu zokwelula.

Udokotela wakho noma usokhemisi uzokunikeza ishidi lemininingwane yesiguli lomkhiqizi (Umhlahlandlela Wezokwelapha) lapho uqala ukwelashwa ngomjovo we-methylnaltrexone futhi isikhathi ngasinye lapho ugcwalisa khona incwadi kadokotela. Funda imininingwane ngokucophelela bese ubuza udokotela noma usokhemisi wakho uma unemibuzo. Ungavakashela futhi iwebhusayithi ye-Food and Drug Administration (FDA) (http://www.fda.gov/Drugs/DrugSafety/ucm085729.htm) ukuthola uMhlahlandlela Wezokwelapha.

Lo muthi ungabekelwa okunye ukusetshenziswa; buza udokotela wakho noma usokhemisi ukuthola eminye imininingwane.

Ngaphambi kokusebenzisa umjovo we-methylnaltrexone,

• Tshela udokotela wakho kanye nosokhemisi uma unegciwane ku-methylnaltrexone, noma imiphi eminye imithi, noma yiziphi izithako zomjovo we-methylnaltrexone. Buza usokhemisi wakho ukuthola uhlu lwezithako.
• Tshela udokotela wakho kanye nosokhemisi ukuthi imiphi eminye imishanguzo kadokotela neyokungabhalisi, amavithamini, izithasiselo zokudla okunempilo, nemikhiqizo yamakhambi oyithathayo noma ohlela ukuyithatha. Qiniseka ukuthi usho noma yikuphi okulandelayo: Udokotela wakho angadinga ukushintsha imithamo yemithi yakho noma akuqaphele ngokucophelela ngemiphumela emibi.
• Tshela udokotela wakho uma uke waba nokuvinjelwa kwamathumbu noma wake waba nokuvaleka emathunjini akho. Udokotela wakho mhlawumbe uzokutshela ukuthi ungasebenzisi umjovo we-methylnaltrexone.
• Tshela udokotela wakho uma uke waba nezinkinga zesisu noma zamathumbu kubandakanya isilonda esiswini (izilonda esiswini sesisu), umdlavuza wesisu noma wamathumbu, isifo sikaCrohn (isimo lapho umzimba uhlasela ulwelwesi lwendlela yokugaya ukudla , kubangela ubuhlungu, isifo sohudo, ukwehla kwesisindo, kanye nomkhuhlane), i-diverticulitis (izikhwama ezincane emgqeni wamathumbu amakhulu angavuvukala), i-Ogilvie's syndrome (isimo lapho kukhona khona ukuqhuma emathunjini), noma izinso noma isibindi isifo.
• utshele udokotela wakho uma ukhulelwe noma uhlela ukukhulelwa. Uma ukhulelwa ngenkathi usebenzisa umjovo we-methylnaltrexone, shayela udokotela wakho. Uma uthola i-methylnaltrexone ngesikhathi ukhulelwe, ingane yakho ingathola izimpawu zokuhoxa kwe-opioid.
• tshela udokotela wakho uma uncelisa. Ungancelisi ibele ngenkathi usebenzisa umjovo we-methylnaltrexone.
• kufanele wazi ukuthi iningi labantu linokuhamba kwamathumbu kungakapheli imizuzu embalwa kuya emahoreni ambalwa ngemuva kokusebenzisa umjovo we-methylnaltrexone. Qiniseka ukuthi useduze nendawo yokugezela lapho usebenzisa lo muthi.

Ngaphandle kokuthi udokotela wakho akutshele ngenye indlela, qhubeka nokudla okuvamile.

Kubantu abathile lo muthi usetshenziswa njengoba kudingeka, kepha kwezinye iziguli lo muthi usetshenziswa nsuku zonke. Uma udokotela wakho ekutshele ukuthi usebenzise umjovo we-methylnaltrexone njalo, sebenzisa umthamo ongabanjwanga ngokushesha nje lapho uwukhumbula. Kodwa-ke, uma sekuyisikhathi somthamo olandelayo, weqa umthamo ongabanjwanga bese uqhubeka neshejuli yakho ejwayelekile yokulinganisa. Ungasebenzisi umthamo ophindwe kabili ukwenza okulahlekile.

Umjovo weMethylnaltrexone ungadala imiphumela emibi. Tshela udokotela wakho uma kukhona kulezi zimpawu ezinzima noma ezingapheli:

• ubuhlungu besisu
• igesi
• isicanucanu
• ukuhlanza
• isifo sohudo
• isiyezi
• ukujuluka
• Ukugodola
• ukukhathazeka
• kuzamula
• ukuthuthumela
• ukushisa okushisayo

Eminye imiphumela emibi ingaba mibi. Uma uhlangabezana nalesi sibonakaliso, yeka ukusebenzisa i-methylnaltrexone bese ushayela udokotela wakho ngokushesha:

• isifo sohudo esibi
• ubuhlungu obukhulu besisu

Umjovo weMethylnaltrexone ungadala eminye imiphumela emibi. Shayela udokotela wakho uma unezinkinga ezingavamile ngenkathi usebenzisa lo muthi.

Uma uthola imiphumela emibi kakhulu, wena noma udokotela wakho ungathumela umbiko kuhlelo lwe-Food and Drug Administration's (FDA) MedWatch Adverse Event Reporting online (http://www.fda.gov/Safety/MedWatch) noma ngocingo ( 1-800-332-1088).

Gcina le mithi ebhokisini efike kuyo, ivalwe ngokuqinile, futhi lapho izingane zingafinyeleleki khona. Yigcine ekamelweni lokushisa futhi ungayifaki iqhwa. Yivikele ekukhanyeni. Uma udonsela i-methylnaltrexone phezulu kwisirinji kodwa ungakwazi ukuyisebenzisa ngokushesha, isirinji ingagcinwa ekamelweni lokushisa kuze kube amahora angama-24. Isiponji asidingi ukuvikelwa ekukhanyeni ngalesi sikhathi.

Kubalulekile ukugcina yonke imishanguzo ingabonakali futhi ifinyeleleke ezinganeni njengoba iziqukathi eziningi (njengezingqondo zamaphilisi zamasonto onke kanye nalawo amaconsi wamehlo, okhilimu, amabala, kanye nama-inhalers) azimeleki ezinganeni futhi izingane ezincane zingazivula kalula. Ukuvikela izingane ezisencane ekufakeni ubuthi, hlala uvala amakepisi okuphepha bese ubeka umuthi endaweni ephephile - eyodwa ephezulu futhi engekho futhi engabonakali kubo futhi efinyelela kuyo. http://www.upandaway.org

Imithi engadingeki kufanele ilahlwe ngezindlela ezikhethekile zokuqinisekisa ukuthi izilwane ezifuywayo, izingane nabanye abantu abakwazi ukuzidla. Kodwa-ke, akufanele ukhiphe le mithi ethoyilethi. Esikhundleni salokho, indlela engcono kakhulu yokulahla imithi yakho ngohlelo lokubuyisa umuthi. Khuluma nosokhemisi wakho noma uthinte umnyango wangakini wokulahla udoti / wokusebenzisa kabusha ukuze ufunde ngezinhlelo zokubuyisa emphakathini wakho. Bheka iwebhusayithi yakwa-FDA's Safe Disposal of Medicines (http://goo.gl/c4Rm4p) ukuthola eminye imininingwane uma ungakwazi ukufinyelela kuhlelo lokubuyisa.

Uma kwenzeka ukweqisa ngokweqile, shayela ucingo losizo lokulawula ubuthi ku-1-800-222-1222. Imininingwane iyatholakala online ku-https: //www.poisonhelp.org/help. Uma isisulu siwile, saba nokuquleka, sinenkinga yokuphefumula, noma singakwazi ukuvuswa, shayela ngokushesha abezimo eziphuthumayo ku-911.

Izimpawu zokudlula ngokweqile zingafaka okulandelayo:

• isiyezi, ikhanda elikhanyayo, nokuquleka lapho uvuka ngokushesha okukhulu endaweni yokulala
• Ukugodola
• ukujuluka
• ikhala eligijimayo
• isifo sohudo
• ubuhlungu besisu
• ukukhathazeka
• kuzamula
• ukwehla kwemiphumela yokudambisa izinhlungu yemithi ye-opioid

Gcina wonke ama-aphoyintimenti nodokotela wakho.

Ungavumeli omunye umuntu asebenzise imithi yakho. Buza usokhemisi wakho noma imiphi imibuzo onayo mayelana nokugcwalisa umuthi wakho.

Kubalulekile ukuthi ugcine uhlu olubhaliwe lwayo yonke imishanguzo oyisebenzisayo kadokotela kanye nokungabhaliswanga (ngaphezulu kokuthenga), kanye nanoma yimiphi imikhiqizo efana namavithamini, amaminerali, noma ezinye izithako zokudla. Kufanele uze nalolu hlu njalo uma uvakashela udokotela noma uma ungeniswa esibhedlela. Kubaluleke kakhulu futhi nemininingwane ebalulekile ukuthi uphathe uma kwenzeka kunezimo eziphuthumayo.

• Ohambisanayo^®