Dabigatran

-Delile

• Ngaphambi kokuthatha i-dabigatran,
• I-Dabigatran ingadala imiphumela emibi. Tshela udokotela wakho uma kukhona kulezi zimpawu:
• Eminye imiphumela emibi ingaba mibi. Uma uhlangabezana nenye yalezi zimpawu noma lezo ezibalwe esigabeni ESIBALULEKILE SEXWAYISO, shayela udokotela wakho ngokushesha noma uthole ukwelashwa okuphuthumayo:
• Izimpawu zokudlula ngokweqile zingafaka okulandelayo:

Uma une-fibrillation ye-atrial (isimo lapho inhliziyo ishaya ngokungajwayelekile, okwandisa amathuba okuba namahlule emzimbeni, futhi mhlawumbe kubangele imivimbo) futhi uthatha i-dabigatran ukusiza ukuvimbela ukushaywa unhlangothi noma amahlule angathi sína egazini, usengozini enkulu yokuba ukushaywa unhlangothi ngemuva kokuyeka ukusebenzisa le mithi. Ungayeki ukuthatha i-dabigatran ngaphandle kokukhuluma nodokotela wakho. Qhubeka uthathe i-dabigatran noma ngabe uzizwa uphilile. Qiniseka ukuthi ugcwalisa kadokotela wakho ngaphambi kokuphelelwa yimithi ukuze ungaphuthelwa yimithamo ye-dabigatran. Uma udinga ukuyeka ukuthatha i-dabigatran, udokotela wakho angahle anikeze enye i-anticoagulant ('blood thinner') ukusiza ukuvimbela igazi ukuba lingakhi futhi likwenze ube nesifo sohlangothi.

Uma une-epidural noma i-spinal anesthesia noma i-puncture yomgogodla ngenkathi uthatha 'i-blood thinner' efana ne-dabigatran, usengozini yokuba nefomu le-clot yegazi emgogodleni noma ezungeze umgogodla wakho ongakwenza ukuthi ukhubazeke. Tshela udokotela wakho uma une-catheter ye-epidural esele emzimbeni wakho noma uke waba nokuphindaphinda ama-epidural noma umgogodla ophindaphindiwe, ukukhubazeka komgogodla noma ukuhlinzwa komgogodla. Tshela udokotela kanye nosokhemisi wakho uma ngabe uthatha noma ikuphi kokulandelayo: i-anagrelide (Agrylin), i-aspirin nezinye izidakamizwa ezingezona ukuvuvukala (ama-NSAID) njenge-ibuprofen (Advil, Motrin), indomethacin (Indocin, Tivorbex), ketoprofen, ne-naproxen (Aleve, Anaprox, abanye), cilostazol (Pletal), clopidogrel (Plavix), dipyridamole (Persantine), eptifibatide (Integrilin), heparin, prasugrel (Effient), ticagrelor (Brilinta), ticlopidine, tirofiban (Aggrastarin) I-Coumadin, iJantoven). Uma uhlangabezana nanoma yiziphi kulezi zimpawu ezilandelayo, shayela udokotela wakho ngokushesha: izinhlungu zasemhlane, ubuthakathaka bemisipha (ikakhulukazi emilenzeni nasezinyaweni), ukuba ndikindiki noma ukuncinza (ikakhulukazi emilenzeni), noma ukulahlekelwa ukulawula amathumbu noma isinye.

Gcina wonke ama-aphoyintimenti nodokotela wakho kanye nelabhorethri. Udokotela wakho angalawula izivivinyo ezithile zelebhu ukuze ahlole impendulo yomzimba wakho ku-dabigatran.

Udokotela wakho noma usokhemisi uzokunikeza ishidi lemininingwane yesiguli lomkhiqizi (Umhlahlandlela Wezokwelapha) lapho uqala ukwelashwa nge-dabigatran futhi isikhathi ngasinye lapho ugcwalisa umuthi wakho. Funda imininingwane ngokucophelela bese ubuza udokotela noma usokhemisi wakho uma unemibuzo. Ungavakashela futhi iwebhusayithi ye-Food and Drug Administration (FDA) (http://www.fda.gov/Drugs/DrugSafety/ucm085729.htm) noma iwebhusayithi yomkhiqizi ukuthola i-Medication Guide.

I-Dabigatran isetshenziselwa ukwelapha i-vein thrombosis ejulile (i-DVT; ihlule legazi, imvamisa emlenzeni) kanye ne-pulmonary embolism (PE; ihlule legazi emaphashini) kubantu abelashelwe i-anticoagulant ejojowe ('blood thinner'). Iphinde isetshenziselwe ukunciphisa ubungozi be-DVT ne-PE ekungenzeki futhi ngemuva kokuthi ukwelashwa kokuqala kuqediwe. I-Dabigatran isetshenziselwa ukusiza ukuvimbela i-DVT ne-PE kubantu abake bahlinzwa kabusha esikhundleni se-hip. IDabigatran ibuye isetshenziselwe ukusiza ukuvimbela imivimbo noma amahlule angathi sína egazini kubantu abane-fibrillation ye-atrial (isimo lapho inhliziyo ishaya ngokungajwayelekile, ikhulisa amathuba okuba namahlule emzimbeni, futhi mhlawumbe abangele imivimbo) ngaphandle kwesifo se-valve senhliziyo. UDabigatran usekilasini lemithi elwa namagciwane ebizwa nge-thrombin inhibitors eqondile. Isebenza ngokuvimbela amahlule egazi ukuthi akhe emzimbeni.

UDabigatran uza njengephilisi elizothathwa ngomlomo. Lapho i-dabigatran isetshenziselwa ukwelapha noma ukuvimbela i-DVT noma i-PE noma ukuvimbela imivimbo noma amahlule amakhulu egazi kubantu abane-fibrillation ye-atrial, kuvame ukuthathwa kabili ngosuku. Lapho i-dabigatran isetshenziselwa ukuvimbela i-DVT noma i-PE ngemuva kokuhlinzwa kwe-hip esikhundleni kuvame ukuthathwa amahora ayi-1 kuye kwayi-4 ngemuva kokuhlinzwa, bese kuthi kanye ngosuku kwezinye izinsuku ezingama-28 kuye kwezingu-35. IDabigatran ingathathwa ngokudla noma ngaphandle kokudla. Thatha i-dabigatran ngezikhathi ezifanayo nsuku zonke. Landela izinkomba ezikulebuli kadokotela wakho ngokucophelela, bese ubuza udokotela noma usokhemisi wakho ukuthi akuchaze nganoma iyiphi ingxenye ongayiqondi. Thatha i-dabigatran njengoba nje kuqondisiwe. Ungayithathi kancane noma uyithathe kaningi kunokuyalelwa ngudokotela wakho.

Gwinya wonke amaphilisi ngengilazi yonke yamanzi; ungawahlukanisi, ungawahlafune noma uwagxoze. Ungavuli amaphilisi bese ufafaza okuqukethwe ekudleni noma eziphuzweni.

IDabigatran izosiza ukuvimbela imivimbo kanye namahlule egazi kuphela uma uqhubeka nokukuthatha. Qhubeka uthathe i-dabigatran noma ngabe uzizwa uphilile. Qiniseka ukuthi ugcwalisa kadokotela wakho ngaphambi kokuphelelwa yimithi ukuze ungaphuthelwa imithamo ye-dabigatran. Ungayeki ukuthatha i-dabigatran ngaphandle kokukhuluma nodokotela wakho. Uma ngokungazelelwe uyeka ukuthatha i-dabigatran, ingozi yokuthi uzoba neqhwa noma isifo sohlangothi inganda.

Lo muthi ungabekelwa okunye ukusetshenziswa; buza udokotela wakho noma usokhemisi ukuthola eminye imininingwane.

Ngaphambi kokuthatha i-dabigatran,

• Tshela udokotela wakho kanye nosokhemisi uma unegciwane ku-dabigatran, noma imiphi eminye imithi, noma yiziphi izithako kuma-capsules e-dabigatran. Buza usokhemisi wakho noma uhlole Umhlahlandlela Wezokwelapha ukuthola uhlu lwezithako.
• Tshela udokotela wakho kanye nosokhemisi ukuthi imiphi imishanguzo kadokotela neyokungabhalisi, amavithamini, izithako zokudla okunempilo, nemikhiqizo yamakhambi oyithathayo noma ohlela ukuyithatha. Qiniseka ukuthi usho noma yikuphi okulandelayo: i-dronedarone (iMultaq), i-ketoconazole (i-Nizoral), ne-rifampin (i-Rifadin, i-Rimactane, e-Rifamate, e-Rifater). Udokotela wakho angadinga ukushintsha imithamo yemithi yakho noma akuqaphele ngokucophelela ngemiphumela emibi.
• Tshela udokotela wakho uma ngabe kufakwe i-valve enhliziyweni yakho noma ngabe usanda kubona noma yikuphi ukulimaza noma ukopha okungavamile. Udokotela wakho mhlawumbe uzokutshela ukuthi ungathathi i-dabigatran.
• utshele udokotela wakho uma uke waba nenkinga yokopha, ukopha noma isilonda esiswini noma emathunjini; noma isifo sezinso.
• utshele udokotela wakho uma ukhulelwe, hlela ukukhulelwa, noma uncelisa. Uma ukhulelwa ngenkathi uthatha i-dabigatran, shayela udokotela wakho. Ukuthatha i-dabigatran kungandisa ubungozi bokuthi uzozwa ukopha kakhulu ngesikhathi sokubeletha nokubeletha.
• khuluma nodokotela wakho ngezingozi nezinzuzo zokuthatha i-dabigatran uma uneminyaka engama-75 noma ngaphezulu.
• uma uhlinzwa, kufaka phakathi ukuhlinzwa kwamazinyo, tshela udokotela noma udokotela wamazinyo ukuthi uthatha i-dabigatran.

Ngaphandle kokuthi udokotela wakho akutshele ngenye indlela, qhubeka nokudla okuvamile.

Thatha umthamo ongabanjwanga ngokushesha nje lapho uwukhumbula. Kodwa-ke, uma ukhumbula umthamo ongabanjwanga ngaphansi kwamahora angu-6 ngaphambi komthamo wakho olandelayo ohleliwe, weqa umthamo ongabanjwanga bese uqhubeka neshejuli yakho ejwayelekile yokulinganisa. Ungathathi umthamo ophindwe kabili ukwenza okulahlekile.

I-Dabigatran ingadala imiphumela emibi. Tshela udokotela wakho uma kukhona kulezi zimpawu:

• ubuhlungu besisu
• isisu esibuhlungu
• isilungulela
• isicanucanu

Eminye imiphumela emibi ingaba mibi. Uma uhlangabezana nenye yalezi zimpawu noma lezo ezibalwe esigabeni ESIBALULEKILE SEXWAYISO, shayela udokotela wakho ngokushesha noma uthole ukwelashwa okuphuthumayo:

• ukulimaza noma ukopha okungavamile
• umchamo obomvana noma onsundu
• okubomvu noma okumnyama, izitulo zokulinda
• ekhwehlela igazi
• izinto zokuhlanza ezinegazi noma ezibukeka njengezizathu zekhofi
• ukuphuma ezinsinini
• ukopha kaningi
• ukuphuma kwegazi okunzima
• ukopha ekusikeni okuhlala isikhathi eside kunokujwayelekile
• ubuhlungu obuhlangene noma ukuvuvukala
• ikhanda
• isiyezi noma ukuzwa ukuquleka
• ubuthakathaka
• isifuba
• ukuqubuka
• ukulunywa
• ukuphefumula kanzima noma ukugwinya
• ubuhlungu besifuba noma ukuqina
• ukuvuvukala kobuso, umphimbo, ulimi, izindebe, amehlo, izingalo, izandla, izinyawo, amaqakala noma imilenze engezansi

I-Dabigatran ingadala eminye imiphumela emibi. Shayela udokotela wakho uma unezinkinga ezingavamile ngenkathi uthatha lo muthi.

Uma uthola imiphumela emibi kakhulu, wena noma udokotela wakho ungathumela umbiko kuhlelo lwe-Food and Drug Administration's (FDA) MedWatch Adverse Event Reporting online (http://www.fda.gov/Safety/MedWatch) noma ngocingo ( 1-800-332-1088).

Gcina le mithi esitsheni efike ngayo, ivalwe ngokuqinile, futhi lapho izingane zingafinyeleleki khona. Musa ukugcina i-dabigatran ebhokisini lephilisi noma kumhleli wamaphilisi. Gcina ekamelweni lokushisa futhi kude nokushisa okweqile nomswakama. Vula ibhodlela elilodwa kuphela le-dabigatran ngasikhathi. Qedela ibhodlela lakho le-dabigatran ngaphambi kokuvula ibhodlela elisha). Lahla noma imuphi umuthi osele esitsheni emva kwezinyanga ezi-4 uwuvulile.

Kubalulekile ukugcina yonke imishanguzo ingabonakali futhi ifinyeleleke ezinganeni njengoba iziqukathi eziningi (njengezingqondo zamaphilisi zamasonto onke kanye nalawo amaconsi wamehlo, okhilimu, amabala, kanye nama-inhalers) azimeleki ezinganeni futhi izingane ezincane zingazivula kalula. Ukuvikela izingane ezisencane ekufakeni ubuthi, hlala uvala amakepisi okuphepha bese ubeka umuthi endaweni ephephile - eyodwa ephezulu futhi engekho futhi engabonakali kubo futhi efinyelela kuyo. http://www.upandaway.org

Imithi engadingeki kufanele ilahlwe ngezindlela ezikhethekile zokuqinisekisa ukuthi izilwane ezifuywayo, izingane nabanye abantu abakwazi ukuzidla. Kodwa-ke, akufanele ukhiphe le mithi ethoyilethi. Esikhundleni salokho, indlela engcono kakhulu yokulahla imithi yakho ngohlelo lokubuyisa umuthi. Khuluma nosokhemisi wakho noma uthinte umnyango wangakini wokulahla udoti / wokusebenzisa kabusha ukuze ufunde ngezinhlelo zokubuyisa emphakathini wakho. Bheka iwebhusayithi yakwa-FDA's Safe Disposal of Medicines (http://goo.gl/c4Rm4p) ukuthola eminye imininingwane uma ungakwazi ukufinyelela kuhlelo lokubuyisa.

Uma kwenzeka ukweqisa ngokweqile, shayela ucingo losizo lokulawula ubuthi ku-1-800-222-1222. Imininingwane iyatholakala online ku-https: //www.poisonhelp.org/help. Uma isisulu siwile, saba nokuquleka, sinenkinga yokuphefumula, noma singakwazi ukuvuswa, shayela ngokushesha abezimo eziphuthumayo ku-911.

Izimpawu zokudlula ngokweqile zingafaka okulandelayo:

• ukulimaza noma ukopha okungavamile
• umchamo obomvana noma onsundu
• okubomvu noma okumnyama, izitulo zokulinda
• izinto zokuhlanza ezinegazi noma ezibukeka njengezizathu zekhofi
• ekhwehlela igazi

Ungavumeli omunye umuntu ukuthi athathe imithi yakho. Buza usokhemisi wakho noma imiphi imibuzo onayo mayelana nokugcwalisa umuthi wakho.

Kubalulekile ukuthi ugcine uhlu olubhaliwe lwayo yonke imishanguzo oyisebenzisayo kadokotela kanye nokungabhaliswanga (ngaphezulu kokuthenga), kanye nanoma yimiphi imikhiqizo efana namavithamini, amaminerali, noma ezinye izithako zokudla. Kufanele uze nalolu hlu njalo uma uvakashela udokotela noma uma ungeniswa esibhedlela. Kubaluleke kakhulu futhi nemininingwane ebalulekile ukuthi uphathe uma kwenzeka kunezimo eziphuthumayo.

• Pradaxa^®