Inaliti yeDenileukin Diftitox

-Delile

• Ngaphambi kokuthatha i-denileukin diftitox,
• I-Denileukin diftitox, ingadala imiphumela emibi. Tshela udokotela wakho uma kukhona kulezi zimpawu ezinzima noma ezingapheli:
• Izimpawu zokudlula ngokweqile zingafaka okulandelayo:

Ungase uthole ukusabela okungathi sína noma okusongela ukuphila ngenkathi uthola umthamo womjovo we-denileukin diftitox. Uzothola umthamo ngamunye wemithi esikhungweni sezokwelapha, futhi udokotela wakho uzokuqapha ngokucophelela ngenkathi uthola lo muthi. Udokotela wakho uzokunika imithi ethile ukuvimbela lokhu kuphendula. Uzophuza le mithi ngomlomo ngaphambi nje kokuba uthole umthamo ngamunye we-denileukin diftitox. Uma uhlangabezana nalezi zimpawu ezilandelayo phakathi noma ngamahora angama-24 ngemuva kokumnika, tshela udokotela wakho ngokushesha: umkhuhlane, amakhaza, isifuba, ukuphefumula kanzima noma ukugwinya, ukuphefumula okuphuzile, ukushaya kwenhliziyo okusheshayo, ukuqina komphimbo, noma ubuhlungu besifuba.

Abanye abantu abathole i-denileukin diftitox baba ne-capillary leak syndrome esongela impilo (isimo esidala ukuthi umzimba ugcine uketshezi oluningi, umfutho ophansi wegazi, namazinga aphansi eprotheni [albumin] egazini). ICapillary leak syndrome kungenzeka kuze kube amasonto ama-2 ngemuva kokunikezwa i-denileukin diftitox futhi ingaqhubeka noma ibe yimbi ngisho nangemva kokuba ukwelashwa kumisiwe. Uma uhlangabezana nalezi zimpawu ezilandelayo, shayela udokotela wakho ngokushesha: ukuvuvukala kwezandla, izinyawo, amaqakala, noma imilenze engezansi; ukukhuluphala; ukuphelelwa umoya; ukuquleka; isiyezi noma ikhanda elikhanyayo; noma ukushaya kwenhliziyo okusheshayo noma okungajwayelekile.

IDenileukin diftitox ingadala ushintsho kumbono, kufaka phakathi ukungaboni kahle, ukulahleka kombono, nokulahleka kombala. Izinguquko zombono zingaba unomphela. Uma uhlangabezana nezinguquko kumbono shayela udokotela wakho ngokushesha.

Gcina wonke ama-aphoyintimenti nodokotela wakho kanye nelabhorethri. Udokotela wakho uzo-oda izivivinyo ezithile ukuze ahlole impendulo yomzimba wakho ku-denileukin diftitox.

I-Denileukin diftitox isetshenziselwa ukwelapha i-T-cell lymphoma (CTCL, iqembu lamagciwane omdlavuza omzimba aqala ukubonakala njengokuqubuka kwesikhumba) kubantu izifo zabo ezingakathuthuki, ziye zaba zimbi kakhulu, noma sebebuyile ngemuva kokuthatha eminye imithi. IDenileukin diftitox isekilasini lemithi ebizwa ngama-cytotoxic protein. Isebenza ngokubulala amangqamuzana omdlavuza.

IDenileukin diftitox iza njengesisombululo (uketshezi) ukujova ngaphezulu kwemizuzu engama-30 kuye kwangama-60 ngemithambo (emthanjeni). IDenileukin diftitox ilawulwa udokotela noma umhlengikazi ehhovisi lezokwelapha noma esikhungweni sokumnika. Imvamisa inikezwa kanye ngosuku izinsuku ezi-5 zilandelana. Lo mjikelezo ungaphindwa njalo ezinsukwini ezingama-21 kuze kube yimijikelezo eyisishiyagalombili.

Lo muthi ungabekelwa okunye ukusetshenziswa; buza udokotela wakho noma usokhemisi ukuthola eminye imininingwane.

Ngaphambi kokuthatha i-denileukin diftitox,

• Tshela udokotela kanye nosokhemisi wakho uma une-aleji ku-denileukin diftitox noma esinye sezithako ku-denileukin diftitox. Buza usokhemisi wakho ukuthola uhlu lwezithako.
• Tshela udokotela wakho kanye nosokhemisi ukuthi imiphi imishanguzo kadokotela neyokungabhalisi, amavithamini, izithako zokudla okunempilo, nemikhiqizo yamakhambi oyithathayo noma ohlela ukuyithatha.
• tshela udokotela wakho uma ukhulelwe, hlela ukukhulelwa, noma uncelisa.

Ngaphandle kokuthi udokotela wakho akutshele ngenye indlela, qhubeka nokudla okuvamile.

Uma uphuthelwa i-aphoyintimenti yokwamukela umthamo we-denileukin diftitox, shayela udokotela wakho khona manjalo.

I-Denileukin diftitox, ingadala imiphumela emibi. Tshela udokotela wakho uma kukhona kulezi zimpawu ezinzima noma ezingapheli:

• isicanucanu
• ukuhlanza
• isifo sohudo
• ukulahlekelwa isifiso sokudla
• shintsha emandleni okunambitha
• ngizizwe ngikhathele
• ubuhlungu, kufaka phakathi emuva, imisipha, noma ubuhlungu obuhlangene
• ukukhwehlela
• ikhanda
• ubuthakathaka
• ukuqubuka
• ukulunywa

Eminye imiphumela emibi ingaba mibi. Uma uhlangabezana nanoma yiziphi izimpawu ezibalwe esigabeni ESIBALULEKILE SEXWAYISO, shayela udokotela wakho ngokushesha.

I-Denileukin diftitox ingadala eminye imiphumela emibi. Shayela udokotela wakho uma unezinkinga ezingavamile ngenkathi uthatha lo muthi.

Uma uthola imiphumela emibi kakhulu, wena noma udokotela wakho ungathumela umbiko kuhlelo lwe-Food and Drug Administration's (FDA) MedWatch Adverse Event Reporting online (http://www.fda.gov/Safety/MedWatch) noma ngocingo ( 1-800-332-1088).

Le mithi izogcinwa ehhovisi likadokotela wakho noma emtholampilo.

Uma kwenzeka ukweqisa ngokweqile, shayela ucingo losizo lokulawula ubuthi ku-1-800-222-1222. Imininingwane iyatholakala online ku-https: //www.poisonhelp.org/help. Uma isisulu siwile, saba nokuquleka, sinenkinga yokuphefumula, noma singakwazi ukuvuswa, shayela ngokushesha abezimo eziphuthumayo ku-911.

Izimpawu zokudlula ngokweqile zingafaka okulandelayo:

• isicanucanu
• ukuhlanza
• imfiva
• Ukugodola
• ubuthakathaka

Buza usokhemisi wakho noma imiphi imibuzo onayo mayelana ne-denileukin diftitox.

Kubalulekile ukuthi ugcine uhlu olubhaliwe lwayo yonke imishanguzo oyisebenzisayo kadokotela kanye nokungabhaliswanga (ngaphezulu kokuthenga), kanye nanoma yimiphi imikhiqizo efana namavithamini, amaminerali, noma ezinye izithako zokudla. Kufanele uze nalolu hlu njalo uma uvakashela udokotela noma uma ungeniswa esibhedlela. Kubaluleke kakhulu futhi nemininingwane ebalulekile ukuthi uphathe uma kwenzeka kunezimo eziphuthumayo.

• Ontak^®