Vismodegib

-Delile

• Ngaphambi kokuthatha i-vismodegib,
• IVismodegib ingadala imiphumela emibi. Tshela udokotela wakho uma kukhona kulezi zimpawu ezinzima noma ezingapheli:

Kuzo zonke iziguli:

IVismodegib akufanele ithathwe ngabesifazane abakhulelwe noma abangakhulelwa. Kukhona ingozi yokuthi i-vismodegib izodala ukulahleka kokukhulelwa noma ibangele ukuthi ingane izalwe inokukhubazeka kokuzalwa (izinkinga zomzimba ezikhona ngesikhathi sokuzalwa).

Udokotela wakho noma usokhemisi uzokunikeza ishidi lemininingwane yesiguli lomkhiqizi (Umhlahlandlela Wezokwelapha) lapho uqala ukwelashwa nge-vismodegib futhi isikhathi ngasinye lapho ugcwalisa khona incwadi kadokotela. Funda imininingwane ngokucophelela bese ubuza udokotela noma usokhemisi wakho uma unemibuzo. Ungavakashela futhi iwebhusayithi ye-Food and Drug Administration (FDA) (http://www.fda.gov/Drugs/DrugSafety/ucm085729.htm) noma uvakashele iwebhusayithi yomkhiqizi ukuthola i-Medication Guide.

Unganikeli ngegazi ngenkathi uthatha i-vismodegib nezinyanga eziyi-7 ngemuva kokwelashwa kwakho.

Ungabelani nge-vismodegib nanoma ngubani omunye umuntu, ngisho nomuntu onezimpawu ezifanayo onazo.

Khuluma nodokotela wakho ngengcuphe (s) yokuthatha i-vismodegib.

Ezigulini zesifazane:

Uma ungakhulelwa, kuzodingeka ugweme ukukhulelwa ngesikhathi sokwelashwa kwakho nge-vismodegib. Kufanele ube nokuhlolwa kokukhulelwa okungekuhle kungakapheli isonto elilodwa uqale ukwelashwa kwakho. Kufanele usebenzise izindlela ezamukelekayo zokulawula ukubeletha ngesikhathi ukwelashwa kwakho nezinyanga eziyi-7 ukwelashwa kwakho sekuqediwe. Udokotela wakho uzokutshela ukuthi yiziphi izindlela zokulawula ukubeletha ezamukelekayo.

Uma ucabanga ukuthi ukhulelwe, uphuthelwa ukuya esikhathini, noma uya ocansini ngaphandle kokulawula ukubeletha ngenkathi uthatha i-vismodegib noma kungakapheli izinyanga eziyi-7 ukwelashwa kwakho, shayela udokotela wakho ngokushesha.

Ezigulini zesilisa:

Kufanele usebenzise ikhondomu njalo uma uhlangana nocansi nowesifazane okhulelwe noma okwazi ukukhulelwa ngenkathi uthatha i-vismodegib futhi izinyanga ezintathu ngemuva kokwelashwa kwakho. Lokhu kuyadingeka noma ngabe une-vasectomy (ukuhlinzwa ukuvimbela isidoda ekuphumeni emzimbeni wakho futhi kubangele ukukhulelwa). Tshela udokotela wakho ngokushesha uma uye ocansini olungaphephile nowesifazane ongakhulelwa noma uma ucabanga nganoma yisiphi isizathu ukuthi umlingani wakho ukhulelwe.

Unganikeli ngesidoda ngenkathi uthatha i-vismodegib nezinyanga ezi-3 ngemuva kokwelashwa kwakho.

I-Vismodegib isetshenziselwa ukwelapha i-basal cell carcinoma (uhlobo lomdlavuza wesikhumba) kubantu abanomdlavuza osakaze kwezinye izingxenye zomzimba. IVismodegib ibuye isetshenziselwe ukwelapha i-basal cell carcinoma engalashwa ngokuhlinzwa noma ngemisebe noma ibuye ngemuva kokuhlinzwa. IVismodegib isekilasini lemithi ebizwa nge-hedgehog pathway inhibitors. Isebenza ngokuvimba ukusebenza kweprotheni ekhombisa ukuthi amangqamuzana omdlavuza ayanda. Lokhu kusiza ukumisa noma ukubambezela ukusabalala kwamangqamuzana omdlavuza futhi kungasiza ekunciphiseni izicubu.

IVismodegib iza njengephilisi elizothathwa ngomlomo. Imvamisa kuthathwa kanye ngosuku noma ngaphandle kokudla. Ukukusiza ukuthi ukhumbule ukuthatha i-vismodegib, yithathe ngasikhathi sinye nsuku zonke. Landela izinkomba ezikulebuli kadokotela wakho ngokucophelela, bese ubuza udokotela noma usokhemisi wakho ukuthi akuchaze nganoma iyiphi ingxenye ongayiqondi. Thatha i-vismodegib njengoba nje kuqondisiwe. Ungayithathi kancane noma uyithathe kaningi kunokuyalelwa ngudokotela wakho.

Gwinya wonke amaphilisi; ungawahlukanisi, ungawahlafune noma uwagxoze.

Lo muthi ungabekelwa okunye ukusetshenziswa; buza udokotela wakho noma usokhemisi ukuthola eminye imininingwane.

Ngaphambi kokuthatha i-vismodegib,

• Tshela udokotela wakho kanye nosokhemisi uma unegciwane ku-vismodegib, noma imuphi omunye umuthi, noma iziphi izithako kuma-vismodegib capsules. Buza usokhemisi wakho noma uhlole Umhlahlandlela Wezokwelapha ukuthola uhlu lwezithako.
• Tshela udokotela wakho kanye nosokhemisi ukuthi imiphi imishanguzo kadokotela neyokungabhalisi, amavithamini, izithako zokudla okunempilo, nemikhiqizo yamakhambi oyithathayo noma ohlela ukuyithatha. Qiniseka ukuthi usho noma yikuphi kokulandelayo: ama-antacids; ama-antibiotic athile afana ne-azithromycin (Z-Pak, Zithromax), i-clarithromycin (i-Biaxin, e-Prevpac), ne-erythromycin (i-E.E.S., i-Eryc, i-Ery-Tab, i-Erythrocin, i-PCE); umuthi wokugaya ukudla, isilungulela, noma izilonda ezifana ne-cimetidine (Tagamet), i-famotidine (i-Pepcid), ne-ranitidine (i-Zantac); nama-proton-pump inhibitors anjenge-dexlansoprazole (Dexilant), i-lansoprazole (i-Prevacid, e-Prevpac), i-omeprazole (i-Prilosec, i-Zegerid), i-pantoprazole (i-Protonix), ne-rabeprazole (i-AcipHex). Udokotela wakho angadinga ukushintsha imithamo yemithi yakho noma akuqaphele ngokucophelela ngemiphumela emibi. Eminye imishanguzo eminingi ingaxhumana ne-vismodegib, ngakho-ke qiniseka ukuthi utshela udokotela wakho ngayo yonke imithi oyiphuzayo, ngisho naleyo engabonakali kulolu hlu.
• ungancelisi ibele ngenkathi uthatha i-vismodegib nezinyanga eziyi-7 ngemuva kokwelashwa kwakho.

Ngaphandle kokuthi udokotela wakho akutshele ngenye indlela, qhubeka nokudla okuvamile.

Yeqa umthamo ophuthelwe bese uqhubeka nesimiso sakho sokulinganisa esivamile. Ungathathi umthamo ophindwe kabili ukwenza okulahlekile.

IVismodegib ingadala imiphumela emibi. Tshela udokotela wakho uma kukhona kulezi zimpawu ezinzima noma ezingapheli:

• ukuphazamiseka kwemisipha
• ubuhlungu obuhlangene
• ukukhathala
• ukulahleka kwezinwele
• shintsha ekutheni izinto zinambitha noma zilahlekelwe kanjani
• ukuncipha kokudla
• ukuncipha komzimba
• isicanucanu
• ukuhlanza
• isifo sohudo
• ukuqunjelwa
• uphuthelwe yizikhathi zokuya esikhathini

IVismodegib ingadala eminye imiphumela emibi. Shayela udokotela wakho uma unezinkinga ezingavamile ngenkathi uthatha lo muthi.

Uma uthola imiphumela emibi kakhulu, wena noma udokotela wakho ungathumela umbiko kuhlelo lwe-Food and Drug Administration's (FDA) MedWatch Adverse Event Reporting online (http://www.fda.gov/Safety/MedWatch) noma ngocingo ( 1-800-332-1088).

Gcina le mithi esitsheni efike ngayo, ivalwe ngokuqinile, futhi lapho izingane zingafinyeleleki khona. Gcina ekamelweni lokushisa futhi kude nokushisa okweqile nomswakama (hhayi endlini yangasese).

Imithi engadingeki kufanele ilahlwe ngezindlela ezikhethekile zokuqinisekisa ukuthi izilwane ezifuywayo, izingane nabanye abantu abakwazi ukuzidla. Kodwa-ke, akufanele ukhiphe le mithi ethoyilethi. Esikhundleni salokho, indlela engcono kakhulu yokulahla imithi yakho ngohlelo lokubuyisa umuthi.Khuluma nosokhemisi wakho noma uthinte umnyango wangakini wokulahla udoti / wokusebenzisa kabusha ukuze ufunde ngezinhlelo zokubuyisa emphakathini wakho. Bheka iwebhusayithi yakwa-FDA's Safe Disposal of Medicines (http://goo.gl/c4Rm4p) ukuthola eminye imininingwane uma ungakwazi ukufinyelela kuhlelo lokubuyisa.

Kubalulekile ukugcina yonke imishanguzo ingabonakali futhi ifinyeleleke ezinganeni njengoba iziqukathi eziningi (njengezingqondo zamaphilisi zamasonto onke kanye nalawo amaconsi wamehlo, okhilimu, amabala, kanye nama-inhalers) azimeleki ezinganeni futhi izingane ezincane zingazivula kalula. Ukuvikela izingane ezisencane ekufakeni ubuthi, hlala uvala amakepisi okuphepha bese ubeka umuthi endaweni ephephile - eyodwa ephezulu futhi engekho futhi engabonakali kubo futhi efinyelela kuyo. http://www.upandaway.org

Uma kwenzeka ukweqisa ngokweqile, shayela ucingo losizo lokulawula ubuthi ku-1-800-222-1222. Imininingwane iyatholakala online ku-https: //www.poisonhelp.org/help. Uma isisulu siwile, saba nokuquleka, sinenkinga yokuphefumula, noma singakwazi ukuvuswa, shayela ngokushesha abezimo eziphuthumayo ku-911.

Gcina wonke ama-aphoyintimenti nodokotela wakho.

Buza usokhemisi wakho noma imiphi imibuzo onayo mayelana nokugcwalisa umuthi wakho.

Kubalulekile ukuthi ugcine uhlu olubhaliwe lwayo yonke imishanguzo oyisebenzisayo kadokotela kanye nokungabhaliswanga (ngaphezulu kokuthenga), kanye nanoma yimiphi imikhiqizo efana namavithamini, amaminerali, noma ezinye izithako zokudla. Kufanele uze nalolu hlu njalo uma uvakashela udokotela noma uma ungeniswa esibhedlela. Kubaluleke kakhulu futhi nemininingwane ebalulekile ukuthi uphathe uma kwenzeka kunezimo eziphuthumayo.

• I-Erivedge^®