Collagenase Clostridium Histolyticum Injection

-Delile

• Ngaphambi kokuthola i-collagenase IClostridium histolyticum umjovo,
• Kubantu abathola i-collagenase yenkontileka kaDupuytren:
• Kwabesilisa abathola i-collagenase yesifo sikaPeyronie:
• Eminye imiphumela emibi ingaba mibi. Uma uhlangabezana nenye yalezi zimpawu, shayela udokotela wakho ngokushesha noma uthole ukwelashwa okuphuthumayo:

Kwabesilisa abathola i-collagenase IClostridium histolyticum umjovo wokwelashwa kwesifo sikaPeyronie:

Ukulimala kabi kwesitho sangasese, kufaka phakathi ukuphuka kwepenile (ukuphuka komzimba), kubikwe ezigulini ezitholayo IClostridium histolyticum umjovo wokwelashwa kwesifo sikaPeyronie. Ukuhlinzwa kungadingeka ukwelapha ukulimala, kepha kwezinye izimo umonakalo ungahlala unomphela. Uma uhlangabezana nanoma yiziphi zalezi zimpawu ezilandelayo, shayela udokotela wakho ngokushesha: umsindo ovelayo noma ukuzwa kupipi elimile; ukwehluleka okungazelelwe kokugcina ukwakhiwa; ubuhlungu epenis; ukulinyazwa, ukopha, noma ukuvuvukala kwenduku; ukuchama okunzima; noma igazi emchameni.

Udokotela wakho noma usokhemisi uzokunikeza ishidi lemininingwane yesiguli lomkhiqizi (Umhlahlandlela Wezokwelapha) lapho uqala ukwelashwa nge-collagenase IClostridium histolyticum njalo uma uthola umuthi. Funda imininingwane ngokucophelela bese ubuza udokotela noma usokhemisi wakho uma unemibuzo. Ungavakashela futhi iwebhusayithi ye-Food and Drug Administration (FDA) (http://www.fda.gov/Drugs) noma iwebhusayithi yomkhiqizi ukuthola uMhlahlandlela Wezokwelapha.

Khuluma nodokotela wakho ngezingozi zokuthola i-collagenase IClostridium histolyticum umjovo.

Collagenase IClostridium histolyticum umjovo usetshenziselwa ukwelapha isivumelwano sikaDupuytren (ukuqina okungenazinhlungu nokuqina kwezicubu [intambo] ngaphansi kwesikhumba entendeni yesandla, okungenza kube nzima ukuqondisa umunwe owodwa noma eminingi) lapho intambo yezicubu ingazwakala lapho ihlolwa . Collagenase IClostridium histolyticum umjovo ubuye usetshenziselwe ukwelapha isifo sikaPeyronie (ukuqina kwezicubu [uqweqwe] ngaphakathi kwepenisi okwenza ipipi ligobeke). Collagenase IClostridium histolyticum umjovo usesigabeni semithi ebizwa ngama-enzyme. Kubantu abanenkontileka kaDupuytren, isebenza ngokusiza ukudiliza intambo yezicubu ezijiyile futhi ivumele iminwe (i) iqondiswe. Kubantu abanesifo sikaPeyronie, kusebenza ngokusiza ukudiliza uqweqwe lwezicubu ezijiyile futhi kuvumela ipipi ukuthi liqondiswe.

Collagenase IClostridium histolyticum umjovo uza njengempuphu ezohlanganiswa noketshezi bese ujovwa ngudokotela. Uma uthola i-collagenase IClostridium histolyticum ukwelapha inkontileka kaDupuytren, udokotela wakho uzofaka umuthi entanjeni ngaphansi kwesikhumba kuphela esandleni esithintekile. Uma uthola i-collagenase IClostridium histolyticum ukwelapha isifo sikaPeyronie, udokotela wakho uzokujova umuthi ku-plaque obangela ukuthi ipipi lakho ligobeke. Udokotela wakho uzokhetha indawo engcono yokujova umuthi ukuze welaphe isimo sakho.

Uma uthola ukwelashwa ngenkontileka kaDupuytren, ungagobisi noma uqondise iminwe yesandla esifakiwe noma ufake ingcindezi endaweni efakiwe ngemuva komjovo wakho. Gcina isandla somjovo siphakamisiwe kuze kufike isikhathi sokulala. Kufanele ubuyele ehhovisi likadokotela wakho ngosuku olulandelayo ngemuva kokujova. Udokotela wakho uzohlola isandla sakho, futhi mhlawumbe ahambise futhi anwebe umunwe ukuze asize ukuqhekeza intambo. Buza udokotela wakho lapho ungalindela ukubona ukuthuthuka, bese ushayela udokotela wakho uma isimo sakho singabi ngcono ngesikhathi esilindelekile. Udokotela wakho kungadingeka ukuthi akunikeze imijovo eyengeziwe uma isimo sakho singathuthuki. Ungenzi umsebenzi okhandlayo ngesandla esifakiwe kuze kube yilapho udokotela ekutshela ukuthi ungakwenza lokho. Udokotela wakho mhlawumbe uzokutshela ukuthi ugqoke isicefe njalo ebusuku (ngesikhathi sokulala) izinyanga ezi-4 ngemuva komjovo. Udokotela wakho angakutshela nokuthi wenze izivivinyo zeminwe usuku ngalunye. Landela izinkomba zikadokotela wakho ngokucophelela bese ucela udokotela ukuthi akuchaze nganoma iyiphi ingxenye ongayiqondi.

Uma uthola ukwelashwa kwesifo sikaPeyronie, udokotela wakho uzokujova i-collagenase IClostridium histolyticum kumthondo wakho, kulandelwe umjovo wesibili izinsuku ezi-1 kuya kwezi-3 ngemuva kokujova kokuqala Kumele ubuyele ehhovisi likadokotela wakho izinsuku ezi-1 ukuya kwezi-3 ngemuva kokujova kwakho kwesibili. Udokotela wakho uzokuhambisa ngobumnene futhi alule ipipi lakho (inqubo yokumodela ye-penile) ukusiza ukuqondisa ipipi lakho. Udokotela wakho uzokutshela nokuthi welule ngobumnene futhi uqondise ipipi lakho ekhaya amasonto ayisithupha emva kwalokho. Landela izinkomba zikadokotela wakho ngokucophelela bese ucela udokotela ukuthi akuchaze nganoma iyiphi ingxenye ongayiqondi. Gwema ukwenza ucansi okungenani amasonto ama-2 ngemuva komjovo wakho wokugcina nangemuva kobuhlungu nokuvuvukala. Udokotela wakho angadinga ukukunikeza imijikelezo yokwelashwa eyengeziwe.

Lo muthi ungabekelwa okunye ukusetshenziswa; buza udokotela wakho noma usokhemisi ukuthola eminye imininingwane.

Ngaphambi kokuthola i-collagenase IClostridium histolyticum umjovo,

• Tshela udokotela wakho kanye nosokhemisi uma unegciwane ku-collagenase IClostridium histolyticum umjovo, i-collagenase ointment (iSantyl), noma imuphi omunye umuthi, noma iziphi izithako ze-collagenase IClostridium histolyticum umjovo. Buza usokhemisi wakho noma uhlole Umhlahlandlela Wezokwelapha ukuthola uhlu lwezithako.
• Tshela udokotela wakho kanye nosokhemisi ukuthi imiphi eminye imishanguzo kadokotela neyokungabhalisi, amavithamini, izithasiselo zokudla okunempilo, nemikhiqizo yamakhambi oyithathayo noma ohlela ukuyithatha. Qiniseka ukuthi usho noma yikuphi kokulandelayo: ama-anticoagulants (’ama-thinner egazi’) njenge-warfarin (i-Coumadin), i-aspirin (ngaphezu kuka-150 mg ngosuku), i-clopidogrel (i-Plavix), ne-prasugrel (i-Effient). Udokotela wakho angadinga ukushintsha imithamo yemithi yakho noma akuqaphele ngokucophelela ngemiphumela emibi.
• utshele udokotela wakho uma uke waba nesimo sokuphuma kwegazi noma esinye isimo sezokwelapha. Futhi, tshela udokotela wakho uma ngabe wake wathola i-collagenase ngaphambilini IClostridium histolyticum umjovo wokwelapha esinye isimo.
• utshele udokotela wakho uma ukhulelwe, hlela ukukhulelwa, noma uncelisa. Uma ukhulelwa ngenkathi uthola i-collagenase IClostridium histolyticum umjovo, shayela udokotela wakho.

Ngaphandle kokuthi udokotela wakho akutshele ngenye indlela, qhubeka nokudla okuvamile.

Collagenase IClostridium histolyticum umjovo ungadala imiphumela emibi. Tshela udokotela wakho uma kukhona kulezi zimpawu ezinzima noma ezingapheli.

Kubantu abathola i-collagenase yenkontileka kaDupuytren:

• ububomvu, ukuvuvukala, isisa, ukulimaza, noma ukopha eduze kwendawo ejoyiwe
• ukulunywa kwesandla esiphathwayo
• ubuhlungu esandleni esiphathwayo
• izindlala ezibuhlungu nezivuvukele endololwaneni noma endaweni engaphansi kwekhwapha

Kwabesilisa abathola i-collagenase yesifo sikaPeyronie:

• ubumnene bezungeza indawo ejojelwe (kanye nangaphezulu kwepipi)
• amabhamuza endaweni yomjovo
• isigaxa endaweni yomjovo
• izinguquko kumbala wesikhumba sowesilisa
• ukulunywa umthondo noma isbuko
• ukwakhiwa okubuhlungu
• Izinkinga zokwakhiwa
• ucansi olubuhlungu

Eminye imiphumela emibi ingaba mibi. Uma uhlangabezana nenye yalezi zimpawu, shayela udokotela wakho ngokushesha noma uthole ukwelashwa okuphuthumayo:

• isifuba
• ukuqubuka
• ukuphefumula kanzima noma ukugwinya
• ukushaqeka
• ubuhlungu besifuba
• ukuvuvukala kobuso, umphimbo, ulimi, izindebe, amehlo, izandla, izinyawo, amaqakala noma imilenze engezansi
• umkhuhlane, umphimbo obuhlungu, amakhaza, ukukhwehlela nezinye izimpawu zokutheleleka
• ukuba ndikindiki, ukuncinza, noma ukwanda kobuhlungu emunweni wakho ophathwayo noma esandleni (ngemuva komjovo wakho noma ngemuva kokuvakashelwa kokulandela)

Lapho i-collagenase IClostridium histolyticum umjovo usetshenziselwa ukwelapha ukwenziwa kwenkontileka kukaDupuytren kungadala ukulimala esandleni okungadinga ukwelashwa ngokuhlinzwa noma kungaba unomphela. Shayela udokotela wakho khona manjalo uma unenkinga yokugoba umunwe wakho ojoviwe esihlakaleni ngemuva kokuvuvukala sekuphelile, noma uma unezinkinga ngokusebenzisa isandla sakho esiphathwayo ngemuva kokuhambela kwakho kokulandela. Khuluma nodokotela wakho ngezingozi zokuthola lo muthi.

Collagenase IClostridium histolyticum umjovo ungadala eminye imiphumela emibi. Shayela udokotela wakho uma unezinkinga ezingavamile ngenkathi uthola lo muthi.

Uma uthola imiphumela emibi kakhulu, wena noma udokotela wakho ungathumela umbiko kuhlelo lwe-Food and Drug Administration's (FDA) MedWatch Adverse Event Reporting online (http://www.fda.gov/Safety/MedWatch) noma ngocingo ( 1-800-332-1088).

Gcina wonke ama-aphoyintimenti nodokotela wakho.

Buza udokotela noma usokhemisi noma imiphi imibuzo onayo mayelana ne-collagenase IClostridium histolyticum umjovo.

Kubalulekile ukuthi ugcine uhlu olubhaliwe lwayo yonke imishanguzo oyisebenzisayo kadokotela kanye nokungabhaliswanga (ngaphezulu kokuthenga), kanye nanoma yimiphi imikhiqizo efana namavithamini, amaminerali, noma ezinye izithako zokudla. Kufanele uze nalolu hlu njalo uma uvakashela udokotela noma uma ungeniswa esibhedlela. Kubaluleke kakhulu futhi nemininingwane ebalulekile ukuthi uphathe uma kwenzeka kunezimo eziphuthumayo.

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