Afatinib

-Delile

• Ngaphambi kokuthatha i-afatinib,
• I-Afatinib ingadala imiphumela emibi. Tshela udokotela wakho uma kukhona kulezi zimpawu ezinzima noma ezingapheli:
• Eminye imiphumela emibi ingaba mibi. Uma uhlangabezana nanoma yiziphi zalezi zimpawu noma lezo ezibalwe esigabeni ESIBALULEKILE SEXWAYISO, yeka ukuthatha i-afatinib bese ushayela udokotela wakho ngokushesha noma uthole ukwelashwa okuphuthumayo:
• Izimpawu zokudlula ngokweqile zingafaka:

I-Afatinib isetshenziselwa ukwelapha izinhlobo ezithile zomdlavuza wamaphaphu wamangqamuzana ongewona omncane osabalalele ezicutshini eziseduze noma kwezinye izingxenye zomzimba. I-Afatinib isekilasini lemithi ebizwa nge-kinase inhibitors. Isebenza ngokuvimba isenzo sento ethile eyenzeka ngokwemvelo engadingeka ukusiza amangqamuzana omdlavuza ukuba ande.

I-Afatinib iza njengethebhulethi ezothathwa ngomlomo. Imvamisa ithathwa esiswini esingenalutho kanye ngosuku, okungenani ihora eli-1 ngaphambi noma amahora amabili ngemuva kokudla isidlo noma isidlo. Thatha i-afatinib ngasikhathi sinye nsuku zonke. Landela izinkomba ezikulebuli kadokotela wakho ngokucophelela, bese ubuza udokotela noma usokhemisi wakho ukuthi akuchaze nganoma iyiphi ingxenye ongayiqondi. Thatha i-afatinib njengoba iqondisiwe. Ungayithathi kancane noma uyithathe kaningi kunokuyalelwa ngudokotela wakho.

Udokotela wakho angamisa ukwelashwa kwakho okwesikhashana noma unomphela noma anciphise umthamo uma uhlangabezana nemiphumela emibi ye-afatinib. Khuluma nodokotela wakho mayelana nokuthi uzizwa kanjani ngesikhathi sokwelashwa kwakho.

Qhubeka uthathe i-afatinib noma ngabe uzizwa uphilile. Ungayeki ukuthatha i-afatinib ngaphandle kokukhuluma nodokotela wakho.

Buza usokhemisi noma udokotela wakho ikhophi lemininingwane yomkhiqizi yesiguli.

Lo muthi ungabekelwa okunye ukusetshenziswa; buza udokotela wakho noma usokhemisi ukuthola eminye imininingwane.

Ngaphambi kokuthatha i-afatinib,

• Tshela udokotela wakho kanye nosokhemisi uma unegciwane ku-afatinib, noma imuphi omunye umuthi, noma iziphi izithako ezibhebheni ze-afatinib. Buza usokhemisi wakho ukuthola uhlu lwezithako.
• Tshela udokotela wakho kanye nosokhemisi ukuthi imiphi imishanguzo kadokotela noma engabhaliswanga, amavithamini, kanye nezithako zokudla okunomsoco ozithathayo noma ohlela ukuzithatha. Qiniseka ukuthi usho noma ikuphi kokulandelayo: amiodarone (Cordarone, Pacerone); imishanguzo ethile yokulwa ne-fungal efana ne-itraconazole (Sporanox) ne-ketoconazole (Nizoral); i-cyclosporine (Gengraf, Neoral, Sandimmune); i-erythromycin (E.E.S., Erythrocin, abanye); imishanguzo ethile yegciwane lengculazi (i-HIV) efana ne-nelfinavir (i-Viracept), i-ritonavir (i-Norvir, e-Kaletra), ne-saquinavir (i-Invirase); imithi ethile yokuquleka efana ne-carbamazepine (Carbatrol, Equetro, Tegretol), phenobarbital, ne-phenytoin (Dilantin); i-quinidine (ku-Nuedexta); i-rifampin (iRimactane, iRifadin, eRifater); itacrolimus (Prograf); kanye ne-verapamil (Calan, Covera, Isoptin, Verelan). Eminye imishanguzo eminingi ingaxhumana ne-afatinib, ngakho-ke qiniseka ukuthi utshela udokotela wakho ngayo yonke imithi oyiphuzayo, ngisho nalawo angaveli kulolu hlu. Udokotela wakho angadinga ukushintsha imithamo yemithi yakho noma akuqaphele ngokucophelela ngemiphumela emibi.
• utshele udokotela wakho ukuthi uthatha miphi imikhiqizo yamakhambi, ikakhulukazi iSt John's wort.
• tshela udokotela wakho uma ungowokuzalwa e-Asia noma uke waba nezinkinga zamaphaphu noma zokuphefumula (ngaphandle komdlavuza wamaphaphu); izinkinga zamehlo, kufaka phakathi amehlo omile; izinkinga zenhliziyo; isifo sesibindi noma sezinso; noma esinye isimo sezokwelapha. Futhi, tshela udokotela wakho uma ugqoka amalensi oxhumana naye.
• utshele udokotela wakho uma ukhulelwe noma uhlela ukukhulelwa. Akufanele ukhulelwe ngenkathi uthatha i-afatinib futhi okungenani amasonto ama-2 ngemuva kokwelashwa kwakho. Khuluma nodokotela wakho ngezindlela zokulawula ukubeletha ongazisebenzisa ngesikhathi sokwelashwa kwakho. Uma ukhulelwa ngenkathi uthatha i-afatinib, shayela udokotela wakho ngokushesha. I-Afatinib ingalimaza umbungu.
• tshela udokotela wakho uma uncelisa. Akufanele uncelise ibele ngenkathi uthatha i-afatinib.
• hlela ukugwema ukuvezwa yilanga ngokungadingekile noma isikhathi eside futhi ugqoke izingubo zokuzivikela, izibuko zelanga, nesikhumba selanga. I-Afatinib ingenza isikhumba sakho sizwele ekukhanyeni kwelanga. Ukuvezwa yilanga kwandisa ubungozi bokuthi uzoba nokuqubuka noma umqubuko ngenkathi welashwa nge-afatinib.

Ngaphandle kokuthi udokotela wakho akutshele ngenye indlela, qhubeka nokudla okuvamile.

Thatha umthamo ongabanjwanga ngokushesha nje lapho uwukhumbula. Kodwa-ke, uma kungaphansi kwamahora angu-12 ngaphambi kokuthi uhlelelwe ukuthatha umthamo wakho olandelayo, weqa umthamo ongabanjwanga bese uqhubeka nesimiso sakho sokulinganisa. Ungathathi umthamo ophindwe kabili ukwenza okulahlekile.

I-Afatinib ingadala imiphumela emibi. Tshela udokotela wakho uma kukhona kulezi zimpawu ezinzima noma ezingapheli:

• ukuqhekeka noma ukuvuvukala kwezindebe noma izilonda emakhoneni omlomo
• isikhumba esomile noma ukulunywa
• ukulahlekelwa isifiso sokudla
• ukutheleleka ngezipikili
• induna
• ukuphuma kwamakhala emakhaleni

Eminye imiphumela emibi ingaba mibi. Uma uhlangabezana nanoma yiziphi zalezi zimpawu noma lezo ezibalwe esigabeni ESIBALULEKILE SEXWAYISO, yeka ukuthatha i-afatinib bese ushayela udokotela wakho ngokushesha noma uthole ukwelashwa okuphuthumayo:

• isifo sohudo
• umlomo owomile, umchamo omnyama, ukuncipha kokujuluka, isikhumba esomile, nezinye izimpawu zokoma
• ukuncipha kokuchama
• ukuvuvukala kwezingalo, izandla, izinyawo, amaqakala, noma imilenze engezansi
• ukuqubuka
• ubuhlungu, ubomvu, ukuxebuka, noma ukushwabana kwesikhumba
• ukuphefumula kanzima
• ukuphelelwa umoya
• ukushaya kwenhliziyo okusheshayo, okungajwayelekile, noma okushaya ngamandla
• ukuzuza kwesisindo ngokungazelelwe
• ukukhwehlela
• imfiva
• ukukhathala ngokweqile
• ubuhlungu engxenyeni engenhla yesisu
• ukulimaza noma ukopha okungavamile
• isicanucanu
• ukuhlanza
• ukuphuzi kwesikhumba noma kwamehlo
• umchamo omnyama
• abomvu, avuvukile, abuhlungu, noma ahlengezela izinyembezi
• izinguquko ezingazelelwe embonweni, kufaka phakathi umbono ophuphuthekile
• ukuzwela ekukhanyeni

I-Afatinib ingadala eminye imiphumela emibi. Shayela udokotela wakho uma unezinkinga ezingavamile ngenkathi uthatha lo muthi.

Uma uthola imiphumela emibi kakhulu, wena noma udokotela wakho ungathumela umbiko kuhlelo lwe-Food and Drug Administration's (FDA) MedWatch Adverse Event Reporting online (http://www.fda.gov/Safety/MedWatch) noma ngocingo ( 1-800-332-1088).

Gcina le mithi esitsheni efike ngayo, ivalwe ngokuqinile, futhi lapho izingane zingafinyeleleki khona. Yigcine ekamelweni lokushisa kude nokukhanya, ukushisa okweqile, nomswakama (hhayi endlini yangasese).

Imithi engadingeki kufanele ilahlwe ngezindlela ezikhethekile zokuqinisekisa ukuthi izilwane ezifuywayo, izingane nabanye abantu abakwazi ukuzidla. Kodwa-ke, akufanele ukhiphe le mithi ethoyilethi. Esikhundleni salokho, indlela engcono kakhulu yokulahla imithi yakho ngohlelo lokubuyisa umuthi. Khuluma nosokhemisi wakho noma uthinte umnyango wangakini wokulahla udoti / wokusebenzisa kabusha ukuze ufunde ngezinhlelo zokubuyisa emphakathini wakho. Bheka iwebhusayithi yakwa-FDA's Safe Disposal of Medicines (http://goo.gl/c4Rm4p) ukuthola eminye imininingwane uma ungakwazi ukufinyelela kuhlelo lokubuyisa.

Kubalulekile ukugcina yonke imishanguzo ingabonakali futhi ifinyeleleke ezinganeni njengoba iziqukathi eziningi (njengezingqondo zamaphilisi zamasonto onke kanye nalawo amaconsi wamehlo, okhilimu, amabala, kanye nama-inhalers) azimeleki ezinganeni futhi izingane ezincane zingazivula kalula. Ukuvikela izingane ezisencane ekufakeni ubuthi, hlala uvala amakepisi okuphepha bese ubeka umuthi endaweni ephephile - eyodwa ephezulu futhi engekho futhi engabonakali kubo futhi efinyelela kuyo. http://www.upandaway.org

Uma kwenzeka ukweqisa ngokweqile, shayela ucingo losizo lokulawula ubuthi ku-1-800-222-1222. Imininingwane iyatholakala online ku-https: //www.poisonhelp.org/help. Uma isisulu siwile, saba nokuquleka, sinenkinga yokuphefumula, noma singakwazi ukuvuswa, shayela ngokushesha abezimo eziphuthumayo ku-911.

Izimpawu zokudlula ngokweqile zingafaka:

• isicanucanu
• ukuhlanza
• ubuthakathaka
• isiyezi
• ikhanda
• ubuhlungu besisu

Gcina wonke ama-aphoyintimenti nodokotela wakho kanye nelabhorethri. Udokotela wakho uzo-oda izivivinyo ezithile zelebhu ukuze ahlole impendulo yomzimba wakho ku-afatinib.

Kubalulekile ukuthi ugcine uhlu olubhaliwe lwayo yonke imishanguzo oyisebenzisayo kadokotela kanye nokungabhaliswanga (ngaphezulu kokuthenga), kanye nanoma yimiphi imikhiqizo efana namavithamini, amaminerali, noma ezinye izithako zokudla. Kufanele uze nalolu hlu njalo uma uvakashela udokotela noma uma ungeniswa esibhedlela. Kubaluleke kakhulu futhi nemininingwane ebalulekile ukuthi uphathe uma kwenzeka kunezimo eziphuthumayo.

• UGilotrif^®