I-Daclatasvir

-Delile

• Ngaphambi kokuthatha i-daclatasvir,
• I-Daclatasvir ingadala imiphumela emibi. Tshela udokotela wakho uma kukhona kulezi zimpawu ezinzima noma ezingapheli:
• Eminye imiphumela emibi ingaba mibi. Uma futhi uthatha i-amiodarone futhi uhlangabezana nanoma yiziphi zalezi zimpawu noma lezo ezingxenyeni EXWAYISAYO EBALULEKILE, shayela udokotela wakho ngokushesha:

IDaclastasvir ayisatholakali e-United States.

Kungenzeka ukuthi usungenwe yi-hepatitis B (igciwane elithelela isibindi futhi lingadala ukulimala kwesibindi) kepha ungabi nazimpawu zesifo. Kulokhu, ukuthatha i-daclatasvir kungandisa ubungozi bokuthi ukutheleleka kwakho kuzoba kubi kakhulu noma kusongele impilo futhi uzoba nezimpawu. Tshela udokotela wakho uma ngabe uke waba nokutheleleka ngegciwane le-hepatitis B. Udokotela wakho uzokuyalela ukuhlolwa kwegazi ukuze abone ukuthi uke waba nokutheleleka kwesifo sikashukela B. Udokotela wakho uzokuhlola futhi nangezimpawu zokutheleleka kwesifo sokusha kwesibindi kohlobo B ngesikhathi nangezinyanga ezimbalwa ngemuva kokwelashwa kwakho. Uma kunesidingo, udokotela wakho angakunika imithi yokwelapha lesi sifo ngaphambi nangesikhathi sokwelashwa kwakho nge-daclatasvir. Uma uhlangabezana nalezi zimpawu ezilandelayo ngesikhathi noma ngemuva kokwelashwa kwakho, shayela udokotela wakho ngokushesha: ukukhathala ngokweqile, ukuphuzi kwesikhumba noma kwamehlo, ukulahlekelwa isifiso sokudla, isicanucanu noma ukuhlanza, indle ephaphathekile, ubuhlungu besisu, noma umchamo omnyama.

Gcina wonke ama-aphoyintimenti nodokotela wakho kanye nelabhorethri. Udokotela wakho angalawula izivivinyo ezithile ngaphambi, ngesikhathi, nangemva kokwelashwa kwakho ukuze ahlole impendulo yomzimba wakho ku-daclatasvir.

Khuluma nodokotela wakho ngobungozi (s) bokuthatha i-daclatasvir.

I-Daclatasvir isetshenziswa kanye nomunye umuthi (i-sofosbuvir [Solvadi]) ukwelapha uhlobo oluthile lwe-hepatitis C engamahlalakhona (ukutheleleka ngegciwane okuqhubekayo okulimaza isibindi). IDaclatasvir isekilasini lemithi elwa namagciwane ebizwa nge-hepatitis C virus (HCV) NS5A inhibitors. Isebenza ngokuvimba igciwane elibangela ukusha kwesibindi kohlobo C ekusakazekeni ngaphakathi komzimba. Akwaziwa ukuthi i-daclatasvir ivimbela ukusakazeka kwesifo sokusha kwesibindi kohlobo C kwabanye abantu.

IDaclatasvir iza njengethebhulethi ezothathwa ngomlomo. Imvamisa kuthathwa nokudla noma ngaphandle kokudla kanye ngosuku. I-Daclatasvir kufanele ithathwe ihlanganiswe ne-sofosbuvir, imvamisa amasonto ayi-12. Thatha i-daclatasvir ngasikhathi sinye nsuku zonke. Landela izinkomba ezikulebuli kadokotela wakho ngokucophelela, bese ubuza udokotela noma usokhemisi wakho ukuthi akuchaze nganoma iyiphi ingxenye ongayiqondi. Thatha i-daclatasvir njengoba iqondisiwe. Ungayithathi kancane noma uyithathe kaningi kunokuyalelwa ngudokotela wakho.

Qhubeka uthathe i-daclatasvir noma ngabe uzizwa uphilile. Ungayeki ukuthatha i-daclatasvir noma i-sofosbuvir ngaphandle kokukhuluma nodokotela wakho.

Buza usokhemisi noma udokotela wakho ikhophi lemininingwane yomkhiqizi yesiguli.

Lo muthi ungabekelwa okunye ukusetshenziswa; buza udokotela wakho noma usokhemisi ukuthola eminye imininingwane.

Ngaphambi kokuthatha i-daclatasvir,

• Tshela udokotela wakho kanye nosokhemisi uma unegciwane ku-daclatasvir, noma imuphi omunye umuthi, noma iziphi izithako kumaphilisi e-daclatasvir. Buza usokhemisi wakho ukuthola uhlu lwezithako.
• Tshela udokotela wakho uma uthatha i-carbamazepine (Carbatrol, Epitol, Equetro, Tegretol, Teril), phenytoin (Dilantin, Phenytek), rifampin (Rifadin, Rimactane, eRifamate, Rifater), noma iSt John's wort. Udokotela wakho mhlawumbe uzokutshela ukuthi ungathathi i-daclatasvir uma uthatha eyodwa noma ngaphezulu yale mithi.
• Tshela udokotela wakho kanye nosokhemisi ukuthi imiphi eminye imishanguzo kadokotela neyokungabhalisi, amavithamini, izithako zokudla okunomsoco, okwenzayo noma ohlela ukukuthatha. Qiniseka ukuthi usho noma ikuphi kokulandelayo: amiodarone (Nexterone, Pacerone); ama-antibiotic athile afana ne-clarithromycin (i-Biaxin, e-Prevpac), i-nafcillin, i-rifapentine (i-Priftin), ne-telithromycin (i-Ketek); ezinye izinto zokuvikela ezifana ne-itraconazole (i-Onmel, i-Sporanox), i-ketoconazole, i-posaconazole (i-Noxafil), ne-voriconazole (i-Vfend); i-bosentan (iTracleer); i-buprenorphine ne-naloxone (i-Suboxone, iZubsolv); imishanguzo ethile yokwehlisa i-cholesterol (ama-statins) njenge-atorvastatin (Lipitor, eCaduet), i-fluvastatin (Lescol), i-pitavastatin (i-Livalo), i-pravastatin (i-Pravachol), i-rosuvastatin (i-Crestor), ne-simvastatin (i-Flolipid, i-Zocor, e-Vytorin); imithi equkethe i-cobicistat (Stribild); dabigatran (Pradaxa); i-dexamethasone; i-digoxin (i-Lanoxin); i-efavirenz (iSustiva, e-Atripla), etravirine (Intelence); ezinye ze-HIV protease inhibitors ezifana ne-atazanavir (Reyataz, e-Evotaz), indinavir (Crixivan), nelfinavir (Viracept), ritonavir (Norvir, eKaletra, Technivie, Viekira Pak), kanye ne-saquinavir (Invirase); i-modafinil (i-Provigil); nefazodone; i-nevirapine (i-Viramune); kanye ne-warfarin (Coumadin, Jantoven). Udokotela wakho angadinga ukushintsha imithamo yemithi yakho noma akuqaphele ngokucophelela ngemiphumela emibi. Eminye imishanguzo eminingi ingaxhumana ne-daclatasvir, ngakho-ke qiniseka ukuthi utshela udokotela wakho ngayo yonke imithi oyiphuzayo, ngisho naleyo engabonakali kulolu hlu.
• Tshela udokotela wakho uma ngabe uke wafakelwa isibindi, noma yiluphi uhlobo lwesifo sesibindi ngaphandle kwesifo sokusha kwesibindi kohlobo C, noma isifo senhliziyo.
• utshele udokotela wakho uma ukhulelwe, hlela ukukhulelwa, noma uncelisa. Uma ukhulelwa ngenkathi uthatha i-daclatasvir, shayela udokotela wakho.

Ngaphandle kokuthi udokotela wakho akutshele ngenye indlela, qhubeka nokudla okuvamile.

Uma ukhumbula umthamo ongabanjwanga ngosuku obekufanele uwuthathe, thatha isilinganiso esilahlekile ngokushesha nje lapho usikhumbula ngalolo suku. Kodwa-ke, uma ungawukhumbuli umthamo ophuthelwe kuze kube usuku olulandelayo, weqa umthamo ophuthelwe bese uqhubeka nesimiso sakho sokulinganisa. Ungathathi imithamo emibili ngosuku olufanayo.

I-Daclatasvir ingadala imiphumela emibi. Tshela udokotela wakho uma kukhona kulezi zimpawu ezinzima noma ezingapheli:

• ikhanda
• isifo sohudo

Eminye imiphumela emibi ingaba mibi. Uma futhi uthatha i-amiodarone futhi uhlangabezana nanoma yiziphi zalezi zimpawu noma lezo ezingxenyeni EXWAYISAYO EBALULEKILE, shayela udokotela wakho ngokushesha:

• duzane nokuquleka noma ukuquleka
• isiyezi noma ikhanda elikhanyayo
• ubuthakathaka noma ukungazizwa kahle
• ukuphelelwa umoya
• ubuhlungu besifuba
• izinkinga zememori
• ukudideka

I-Daclatasvir ingadala eminye imiphumela emibi. Shayela udokotela wakho uma unezinkinga ezingavamile ngenkathi uthatha lo muthi.

Uma uthola imiphumela emibi kakhulu, wena noma udokotela wakho ungathumela umbiko kuhlelo lwe-Food and Drug Administration's (FDA) MedWatch Adverse Event Reporting online (http://www.fda.gov/Safety/MedWatch) noma ngocingo ( 1-800-332-1088).

Gcina le mithi esitsheni efike ngayo, ivalwe ngokuqinile, futhi lapho izingane zingafinyeleleki khona. Gcina ekamelweni lokushisa futhi kude nokushisa okweqile nomswakama (hhayi endlini yangasese).

Kubalulekile ukugcina yonke imishanguzo ingabonakali futhi ifinyeleleke ezinganeni njengoba iziqukathi eziningi (njengezingqondo zamaphilisi zamasonto onke kanye nalawo amaconsi wamehlo, okhilimu, amabala, kanye nama-inhalers) azimeleki ezinganeni futhi izingane ezincane zingazivula kalula. Ukuvikela izingane ezisencane ekufakeni ubuthi, hlala uvala amakepisi okuphepha bese ubeka umuthi endaweni ephephile - eyodwa ephezulu futhi engekho futhi engabonakali kubo futhi efinyelela kuyo. http://www.upandaway.org

Imithi engadingeki kufanele ilahlwe ngezindlela ezikhethekile zokuqinisekisa ukuthi izilwane ezifuywayo, izingane nabanye abantu abakwazi ukuzidla. Kodwa-ke, akufanele ukhiphe le mithi ethoyilethi. Esikhundleni salokho, indlela engcono kakhulu yokulahla imithi yakho ngohlelo lokubuyisa umuthi. Khuluma nosokhemisi wakho noma uthinte umnyango wangakini wokulahla udoti / wokusebenzisa kabusha ukuze ufunde ngezinhlelo zokubuyisa emphakathini wakho. Bheka iwebhusayithi yakwa-FDA's Safe Disposal of Medicines (http://goo.gl/c4Rm4p) ukuthola eminye imininingwane uma ungakwazi ukufinyelela kuhlelo lokubuyisa.

Uma kwenzeka ukweqisa ngokweqile, shayela ucingo losizo lokulawula ubuthi ku-1-800-222-1222. Imininingwane iyatholakala online ku-https: //www.poisonhelp.org/help. Uma isisulu siwile, saba nokuquleka, sinenkinga yokuphefumula, noma singakwazi ukuvuswa, shayela ngokushesha abezimo eziphuthumayo ku-911.

Ungavumeli omunye umuntu ukuthi athathe imithi yakho. Buza usokhemisi wakho noma imiphi imibuzo onayo mayelana nokugcwalisa umuthi wakho.

Kubalulekile ukuthi ugcine uhlu olubhaliwe lwayo yonke imishanguzo oyisebenzisayo kadokotela kanye nokungabhaliswanga (ngaphezulu kokuthenga), kanye nanoma yimiphi imikhiqizo efana namavithamini, amaminerali, noma ezinye izithako zokudla. Kufanele uze nalolu hlu njalo uma uvakashela udokotela noma uma ungeniswa esibhedlela. Kubaluleke kakhulu futhi nemininingwane ebalulekile ukuthi uphathe uma kwenzeka kunezimo eziphuthumayo.

• UDaklinza^®