I-Brexpiprazole

-Delile

• Ngaphambi kokuthatha i-brexpiprazole,
• IBrexpiprazole ingadala imiphumela emibi. Tshela udokotela wakho uma kukhona kulezi zimpawu ezinzima noma ezingapheli:
• Eminye imiphumela emibi ingaba mibi. Uma uhlangabezana nanoma yiziphi zalezi zimpawu, noma lezo ezifakwe kuhlu KWEZIXWAYISO EZIBALULEKILE kanye NEZINYATHELO EZIKHETHEKILE, shayela udokotela wakho ngokushesha:

Isexwayiso esibalulekile kubantu abadala asebekhulile abanokuwohloka komqondo:

Ucwaningo lukhombisile ukuthi abantu abadala asebekhulile abanenkinga yokuwohloka komqondo (ukuphazamiseka ebuchosheni okuthinta amandla okukhumbula, ukucabanga kahle, ukuxhumana, nokwenza imisebenzi yansuku zonke futhi lokho kungadala ushintsho esimweni sengqondo nobuntu) abathatha imishanguzo yokuthithibula (imishanguzo yokugula ngengqondo) njenge-brexpiprazole babe nethuba elandayo lokufa ngesikhathi sokwelashwa. Abantu abadala asebekhulile abanenkinga yokuwohloka komqondo futhi bangaba nethuba elikhulu lokuba nesifo sohlangothi noma i-ministroke ngenkathi belashwa ngama-antipsychotic.

IBrexpiprazole ayivunyelwe yi-Food and Drug Administration (FDA) ekwelapheni ukuphazamiseka kokuziphatha kubantu abadala abanesifo sengqondo esiyingozi. Khuluma nodokotela onikeze lo muthi uma wena, ilungu lomndeni, noma omunye umuntu omnakekelayo enesifo sengqondo sokuphazamiseka ngokomqondo futhi ethatha i-brexpiprazole. Ngeminye imininingwane vakashela iwebhusayithi ye-FDA: http://www.fda.gov/Drugs.

Isexwayiso esibalulekile kubantu abanokudangala:

Inani elincane lezingane, intsha, kanye nabantu abadala abancane (abangafika eminyakeni engama-24 ubudala) abathathe imishanguzo yokudangala ngesikhathi sezifundo zokwelashwa baba ukuzibulala (becabanga ngokuzilimaza noma ukuzibulala noma ukuhlela noma ukuzama ukwenza njalo). Izingane, intsha, kanye nabantu abadala abasebancane abathatha imishanguzo yokulwisana nokucindezelwa ukwelapha ukudangala noma ezinye izifo zengqondo bangase babe sethubeni lokuzibulala kunezingane, intsha kanye nabantu abadala abangawasebenzisi ama-anti-depressants ukwelapha lezi zimo. Kodwa-ke, ochwepheshe abaqiniseki ngokuthi le ngozi ingakanani nokuthi kufanele icatshangelwe kangakanani ekunqumeni ukuthi ingane noma osemusha kufanele yini athathe i-anti-depressant. Izingane ezingaphansi kweminyaka engu-18 ubudala akufanele zivame ukuthatha i-brexpiprazole ukwelapha ukucindezeleka, kodwa kwezinye izimo, udokotela anganquma ukuthi i-brexpiprazole iyimithi engcono kakhulu yokwelapha isimo sengane.

Kufanele wazi ukuthi impilo yakho yengqondo ingashintsha ngezindlela ezingalindelekile lapho uthatha i-brexpiprazole noma amanye ama-anti-depressants noma ngabe umdala ngaphezu kweminyaka engama-24. Ungazibulala, ikakhulukazi ekuqaleni kokwelashwa kwakho futhi noma nini lapho umthamo wakho wanda noma kwehlile. Wena, umndeni wakho, noma umnakekeli wakho kufanele ushayele udokotela wakho ngokushesha uma uhlangabezana nalezi zimpawu ezilandelayo: ukucindezeleka okusha noma okuya kuba kubi; ukukhathazeka okusha noma okukhulayo; ukucabanga ngokuzilimaza noma ukuzibulala, noma ukuhlela noma ukuzama ukwenza kanjalo; ukukhathazeka ngokweqile; ukuyaluza; ukwethuka; ubunzima bokulala noma ukulala; isimilo esinolaka; ukucasuka; ukwenza ngaphandle kokucabanga; ukungahlaliseki okukhulu; kanye ne-mania (ukukhungatheka, imizwa ejabule ngokungavamile). Qiniseka ukuthi umndeni wakho noma umnakekeli wakho uyazi ukuthi yiziphi izimpawu ezingaba zimbi kakhulu ukuze bakwazi ukubiza udokotela uma ungakwazi ukuzifunela ukwelashwa wedwa.

Khuluma nodokotela wakho ngobungozi (ub) bokuthatha i-brexpiprazole.

IBrexpiprazole isetshenziselwa ukwelapha izimpawu zeschizophrenia (ukugula ngengqondo okubanga ukuphazamiseka noma ukucabanga okungajwayelekile, ukuphelelwa yintshisekelo empilweni, kanye nemizwelo eqinile noma engafanele). Ibuye isetshenziswe ne-anti-depressant ukuphatha ukucindezeleka lapho izimpawu zingalawulwa yi-anti-depressant yodwa. IBrexpiprazole ikusigaba semithi esibizwa ngokuthi yi-atypical antipsychotic. Isebenza ngokushintsha ukusebenza kwezinto ezithile zemvelo ebuchosheni.

IBrexpiprazole iza njengethebhulethi ezothathwa ngomlomo. Kuvame ukuthathwa kanye ngosuku. Thatha i-brexpiprazole ngasikhathi sinye nsuku zonke. Landela izinkomba ezikulebuli kadokotela wakho ngokucophelela, bese ubuza udokotela noma usokhemisi wakho ukuthi akuchaze nganoma iyiphi ingxenye ongayiqondi. Thatha i-brexpiprazole njengoba nje iyalelwe. Ungayithathi kancane noma uyithathe kaningi kunokuyalelwa ngudokotela wakho.

Udokotela wakho angakuqala ngomthamo ophansi we-brexpiprazole futhi kancane kancane andise umthamo wakho kuye ngokuthi umuthi usebenza kanjani kuwe kanye nemiphumela emibi oyitholayo.

IBrexpiprazole ilawula i-schizophrenia kanye nokudangala kepha ayizelaphi lezi zimo. Qhubeka nokuphuza i-brexpiprazole noma ngabe uzizwa uphilile. Ungayeki ukuthatha i-brexpiprazole ngaphandle kokukhuluma nodokotela wakho.

Lo muthi ungabekelwa okunye ukusetshenziswa; buza udokotela wakho noma usokhemisi ukuthola eminye imininingwane.

Ngaphambi kokuthatha i-brexpiprazole,

• Tshela udokotela kanye nosokhemisi wakho uma unegciwane ku-brexpiprazole, noma imuphi omunye umuthi, noma iziphi izithako ezikumaphilisi e-brexpiprazole. Buza usokhemisi wakho ukuthola uhlu lwezithako.
• Tshela udokotela wakho kanye nosokhemisi ukuthi imiphi eminye imishanguzo kadokotela neyokungabhalisi, amavithamini, kanye nezithako zokudla okunomsoco ozithathayo noma ohlela ukuzithatha. Qinisekisa ukusho noma yikuphi kokulandelayo: imishanguzo efana ne-duloxetine (Cymbalta), i-fluoxetine (i-Prozac, i-Sarafem, i-Symbyax), ne-paroxetine (i-Brisdelle, i-Paxil); imishanguzo ethile yokulwa nobuthi efana ne-fluconazole (i-Diflucan), i-itraconazole (i-Onmel, i-Sporanox), ne-ketoconazole (i-Extina, i-Nizoral, i-Xolegel); i-clarithromycin (i-Biaxin, ku-Prevpac); imithi yokulawula umfutho wegazi ophakeme; i-quinidine (ku-Nuedexta); kanye ne-rifampin (Rifadin, Rimactane, eRifamate, Rifater). Udokotela wakho angadinga ukushintsha imithamo yemithi yakho noma akuqaphele ngokucophelela ngemiphumela emibi. Eminye imishanguzo eminingi ingaxhumana ne-brexpiprazole, ngakho-ke qiniseka ukuthi utshela udokotela wakho ngayo yonke imithi oyiphuzayo, ngisho naleyo engabonakali kulolu hlu.
• utshele udokotela wakho ukuthi uthatha miphi imikhiqizo yamakhambi, ikakhulukazi iSt John's wort.
• utshele udokotela wakho noma uma wena noma omunye emndenini wakho unesifo sikashukela noma wake waba naso. Tshela udokotela uma uke wahlaselwa isifo sohlangothi, i-ministroke (TIA), ubuhlungu besifuba, isifo senhliziyo, isifo senhliziyo, ukushaya kwenhliziyo okungajwayelekile, ukwehluleka kwenhliziyo, inkinga yokugcina ibhalansi yakho, noma isiphi isimo esenza kube nzima ngawe ukugwinya, umfutho wegazi ophakeme noma ophansi, ukuquleka, izinga eliphakeme lamafutha (i-cholesterol ne-triglycerides) egazini lakho, inani eliphansi lamaseli amhlophe egazi, noma isifo sezinso noma sesibindi. Phinda utshele udokotela wakho uma uhlanza kakhulu noma uhudo noma izimpawu zokuphelelwa amandla emzimbeni manje, noma uma uba nalezi zimpawu noma kunini ngesikhathi sokwelashwa kwakho.
• Tshela udokotela wakho uma ukhulelwe, ikakhulukazi uma usezinyangeni ezimbalwa ezedlule zokukhulelwa kwakho, noma uma uhlela ukukhulelwa noma ukuncelisa. Uma ukhulelwa ngenkathi uthatha i-brexpiprazole, shayela udokotela wakho. IBrexpiprazole ingadala izinkinga ezinganeni ezisanda kuzalwa ngemuva kokubeletha uma zithathwa ezinyangeni zokugcina zokukhulelwa.
• kufanele wazi ukuthi i-brexpiprazole ingakwenza ukozele. Ungashayeli imoto noma usebenzise imishini enobungozi uze wazi ukuthi lo muthi ukuthinta kanjani.
• kufanele wazi ukuthi ungathola i-hyperglycemia (iyanda kushukela wakho wegazi) ngenkathi uthatha lo muthi, noma ngabe awunaso vele isifo sikashukela. Uma une-schizophrenia, kungenzeka ukuthi ube nesifo sikashukela kunabantu abangenayo i-schizophrenia, futhi ukuthatha i-brexpiprazole noma imishanguzo efanayo kungakhuphula le ngozi. Tshela udokotela wakho ngokushesha uma unezinye zalezi zimpawu ezilandelayo ngenkathi uthatha i-brexpiprazole: ukoma ngokweqile, ukuchama kaningi, ukulamba ngokweqile, ukungaboni kahle, noma ubuthakathaka. Kubaluleke kakhulu ukubiza udokotela wakho ngokushesha uma unezinye zalezi zimpawu, ngoba ushukela ophakeme wegazi ungadala isimo esibi esibizwa nge-ketoacidosis. I-Ketoacidosis ingasongela impilo uma ingelashwa kusenesikhathi. Izimpawu ze-ketoacidosis zifaka phakathi umlomo owomile, isicanucanu nokuhlanza, ukuphefumula okuncane, ukuphefumula okunuka izithelo, nokuncipha kokwazi.
• kufanele wazi ukuthi i-brexpiprazole ingadala isizungu, ikhanda elikhanyayo, nokuquleka lapho uvuka ngokushesha okukhulu endaweni yokulala. Lokhu kuvame kakhulu lapho uqala ukuthatha i-brexpiprazole. Ukusiza ukugwema le nkinga, phuma embhedeni kancane, uphumule izinyawo zakho phansi imizuzu embalwa ngaphambi kokuma.
• kufanele wazi ukuthi i-brexpiprazole ingenza kube nzima ukuthi umzimba wakho uphole lapho kushisa kakhulu. Tshela udokotela wakho uma uhlela ukuzivocavoca umzimba noma ukuvezwa ukushisa okukhulu.
• kufanele wazi ukuthi i-brexpiprazole ingadala ukwanda kwesisindo. Kubalulekile ukuthi uhlolwe isisindo sakho ngezikhathi ezithile ngenkathi uthatha lo muthi.

Ngaphandle kokuthi udokotela wakho akutshele ngenye indlela, qhubeka nokudla okuvamile.

Thatha umthamo ongabanjwanga ngokushesha nje lapho uwukhumbula. Kodwa-ke, uma sekuyisikhathi somthamo olandelayo, weqa umthamo ongabanjwanga bese uqhubeka neshejuli yakho ejwayelekile yokulinganisa. Ungathathi umthamo ophindwe kabili ukwenza okulahlekile.

IBrexpiprazole ingadala imiphumela emibi. Tshela udokotela wakho uma kukhona kulezi zimpawu ezinzima noma ezingapheli:

• ikhanda
• ukuqunjelwa
• isilungulela
• ukukhathala
• ukuzamazama okungalawuleki kwengxenye yomzimba
• isiyezi, ukuzizwa ungagxilile, noma unenkinga yokugcina ibhalansi yakho

Eminye imiphumela emibi ingaba mibi. Uma uhlangabezana nanoma yiziphi zalezi zimpawu, noma lezo ezifakwe kuhlu KWEZIXWAYISO EZIBALULEKILE kanye NEZINYATHELO EZIKHETHEKILE, shayela udokotela wakho ngokushesha:

• ukuqubuka
• isifuba
• ukulunywa
• ukuvuvukala kwamehlo, ubuso, umlomo, izindebe, ulimi, umphimbo, izandla, izinyawo, amaqakala noma imilenze engezansi
• ukuphefumula kanzima noma ukugwinya
• isithuthwane
• ukuphelelwa umoya
• umphimbo obuhlungu, ukukhwehlela, ukubanda, nezinye izimpawu zokutheleleka
• umkhuhlane, ukujuluka, ukudideka, ukushaya kwenhliziyo okusheshayo noma okungajwayelekile, nokuqina kwemisipha okunzima
• ukunyakaza okungajwayelekile kobuso bakho noma komzimba ongeke ukwazi ukukulawula
• ukuwa
• ukuqina kwemisipha yentamo
• ukuqina emphinjeni

IBrexpiprazole ingadala eminye imiphumela emibi. Shayela udokotela wakho uma unezinkinga ezingavamile ngenkathi uthatha lo muthi.

Uma uthola imiphumela emibi kakhulu, wena noma udokotela wakho ungathumela umbiko kuhlelo lwe-Food and Drug Administration's (FDA) MedWatch Adverse Event Reporting online (http://www.fda.gov/Safety/MedWatch) noma ngocingo ( 1-800-332-1088).

Gcina le mithi esitsheni efike ngayo, ivalwe ngokuqinile, futhi lapho izingane zingafinyeleleki khona. Gcina ekamelweni lokushisa futhi kude nokushisa okweqile nomswakama (hhayi endlini yangasese).

Imithi engadingeki kufanele ilahlwe ngezindlela ezikhethekile zokuqinisekisa ukuthi izilwane ezifuywayo, izingane nabanye abantu abakwazi ukuzidla. Kodwa-ke, akufanele ukhiphe le mithi ethoyilethi. Esikhundleni salokho, indlela engcono kakhulu yokulahla imithi yakho ngohlelo lokubuyisa umuthi. Khuluma nosokhemisi wakho noma uthinte umnyango wangakini wokulahla udoti / wokusebenzisa kabusha ukuze ufunde ngezinhlelo zokubuyisa emphakathini wakho. Bheka iwebhusayithi yakwa-FDA's Safe Disposal of Medicines (http://goo.gl/c4Rm4p) ukuthola eminye imininingwane uma ungakwazi ukufinyelela kuhlelo lokubuyisa.

Kubalulekile ukugcina yonke imishanguzo ingabonakali futhi ifinyeleleke ezinganeni njengoba iziqukathi eziningi (njengezingqondo zamaphilisi zamasonto onke kanye nalawo amaconsi wamehlo, okhilimu, amabala, kanye nama-inhalers) azimeleki ezinganeni futhi izingane ezincane zingazivula kalula. Ukuvikela izingane ezisencane ekufakeni ubuthi, hlala uvala amakepisi okuphepha bese ubeka umuthi endaweni ephephile - eyodwa ephezulu futhi engekho futhi engabonakali kubo futhi efinyelela kuyo. http://www.upandaway.org

Uma kwenzeka ukweqisa ngokweqile, shayela ucingo losizo lokulawula ubuthi ku-1-800-222-1222. Imininingwane iyatholakala online ku-https: //www.poisonhelp.org/help. Uma isisulu siwile, saba nokuquleka, sinenkinga yokuphefumula, noma singakwazi ukuvuswa, shayela ngokushesha abezimo eziphuthumayo ku-911.

Gcina wonke ama-aphoyintimenti nodokotela wakho kanye nelabhorethri. Udokotela wakho anga-oda izivivinyo ezithile zelebhu ukuze ahlole impendulo yomzimba wakho ku-brexpiprazole.

Ungavumeli omunye umuntu ukuthi athathe imithi yakho. Buza usokhemisi wakho noma imiphi imibuzo onayo mayelana nokugcwalisa umuthi wakho.

Kubalulekile ukuthi ugcine uhlu olubhaliwe lwayo yonke imishanguzo oyisebenzisayo kadokotela kanye nokungabhaliswanga (ngaphezulu kokuthenga), kanye nanoma yimiphi imikhiqizo efana namavithamini, amaminerali, noma ezinye izithako zokudla. Kufanele uze nalolu hlu njalo uma uvakashela udokotela noma uma ungeniswa esibhedlela. Kubaluleke kakhulu futhi nemininingwane ebalulekile ukuthi uphathe uma kwenzeka kunezimo eziphuthumayo.

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