I-Eluxadoline

-Delile

• Ngaphambi kokuthatha i-eluxadoline,
• I-Eluxadoline ingadala imiphumela emibi. Tshela udokotela wakho uma kukhona kulezi zimpawu ezinzima noma ezingapheli:
• Eminye imiphumela emibi ingaba mibi. Uma uhlangabezana nenye yalezi zimpawu, yeka ukuthatha i-eluxadoline bese ushayela udokotela wakho ngokushesha noma uthole ukwelashwa okuphuthumayo:

I-Eluxadoline isetshenziselwa ukwelapha isifo samathumbu esibuhlungu ngesifo sohudo (IBS-D; isimo esidala ubuhlungu besisu, ukuqunjelwa, noma izitulo ezixegayo noma ezinamanzi) kubantu abadala. I-Eluxadoline isekilasini lemithi ebizwa ngama-mu-opioid receptor agonists.Isebenza ngokunciphisa umsebenzi wamathumbu.

I-Eluxadoline iza njengethebhulethi ezothathwa ngomlomo. Imvamisa kuthathwa ngokudla kabili ngosuku. Thatha i-eluxadoline ngasikhathi sinye nsuku zonke. Landela izinkomba ezikulebuli kadokotela wakho ngokucophelela, bese ubuza udokotela noma usokhemisi wakho ukuthi akuchaze nganoma iyiphi ingxenye ongayiqondi. Thatha i-eluxadoline njengoba nje iqondisiwe. Ungayithathi kancane noma uyithathe kaningi kunokuyalelwa ngudokotela wakho.

I-Eluxadoline ingahle yenze umkhuba. Ungathathi umthamo omkhulu, uthathe kaningi, noma uthathe isikhathi eside kunokuyalelwa ngudokotela wakho.

Lo muthi ungabekelwa okunye ukusetshenziswa; buza udokotela wakho noma usokhemisi ukuthola eminye imininingwane.

Ngaphambi kokuthatha i-eluxadoline,

• Tshela udokotela kanye nosokhemisi wakho uma uxabana ne-eluxadoline, noma imiphi eminye imithi, noma iziphi izithako ezikumaphilisi e-eluxadoline. Buza usokhemisi wakho noma uhlole Umhlahlandlela Wezokwelapha ukuthola uhlu lwezithako.
• Tshela udokotela wakho kanye nosokhemisi ukuthi imiphi eminye imishanguzo kadokotela neyokungabhalisi, amavithamini, izithasiselo zokudla okunempilo, nemikhiqizo yamakhambi oyithathayo noma ohlela ukuyithatha. Qiniseka ukuthi usho noma ikuphi kokulandelayo: alfentanil (Alfenta); i-alosetron (Lotronex); ama-antibiotic afana ne-ciprofloxacin (Cipro) ne-clarithromycin (i-Biaxin, e-Prevpac); imishanguzo ye-anticholinergic efana ne-benztropine (Cogentin), i-dicyclomine (i-Bentyl), i-diphenhydramine (i-Benadryl); i-bupropion (Forfivo XL, Wellbutrin, Zyban, abanye); i-eltrombopag (i-Promacta); imishanguzo yohlobo lwe-ergot efana ne-dihydroergotamine (i-DHE 45, i-Migranal) ne-ergotamine tartrate (i-Ergomar, eCafergot, eMigergot); fentanyl (Abstral, Actiq, Duragesic, Sublimaze, abanye); i-fluconazole (iDiflucan); gemfibrozil (Lopid); imishanguzo ye-HIV efana ne-atazanavir (Reyataz, e-Evotaz), lopinavir (Kaletra), ritonavir (Norvir, e-Kaletra, e-Viekira Pak), i-saquinavir (i-Invirase), ne-tipranavir (i-Aptivus); imithi evimbela amasosha omzimba njenge-cyclosporine (Gengraf, Neoral, Sandimmune), sirolimus (Rapamune), ne-tacrolimus (Astagraf, Envarsus XR, Prograf); i-opiate (narcotic) imithi yezinhlungu; i-paroxetine (Brisdelle, Paxil, Pexeva); ipimozide (i-Orap); i-quinidine (ku-Nuedexta); i-rifampin (iRifadin, iRimactane, eRifamate, eRifater); kanye ne-rosuvastatin (Crestor). Udokotela wakho angadinga ukushintsha imithamo yemithi yakho noma akuqaphele ngokucophelela ngemiphumela emibi.
• kufanele wazi ukuthi ungathatha i-loperamide (Imodium AD) ngezikhathi ezithile ukwelapha isifo sohudo esibi ngenkathi uthatha i-eluxadoline. Yeka ukuthatha i-loperamide ngokushesha uma uqunjelwa.
• Tshela udokotela wakho uma unesifo sokuqunjelwa manje noma uvame ukuqunjelwa, uma uphuza noma wake waphuza utshwala obuningi (iziphuzo ezingaphezu kwezingu-3 ngosuku), noma uma ungenayo i-gallbladder. Phinda utshele udokotela wakho uma uke waba nokuvinjelwa kwe-bile duct (ukuvinjelwa kumashubhu athwala i-bile kusuka esibindini kuya enyongweni nasemathunjini amancane), i-sphincter ye-Oddi dysfunction (ukuvinjelwa kwenyongo noma amajusi wokugaya agelezela emathunjini adala ubuhlungu noma i-jaundice), ukuvinjelwa emathunjini akho, i-pancreatitis (ukuvuvukala kwamanyikwe okungapheli), noma isifo sesibindi. Udokotela wakho mhlawumbe uzokutshela ukuthi ungathathi i-eluxadoline.
• Tshela udokotela wakho uma uke waba nesifo sezinso noma wake waba naso.
• utshele udokotela wakho uma ukhulelwe, hlela ukukhulelwa, noma uncelisa. Uma ukhulelwa ngenkathi uthatha i-eluxadoline, shayela udokotela wakho.
• kufanele wazi ukuthi i-eluxadoline ingakwenza ukozele, ikakhulukazi uma unesifo sesibindi. Ungashayeli imoto noma usebenzise imishini uze wazi ukuthi lo muthi ukuthinta kanjani.
• utshele udokotela wakho uma uphuza njalo utshwala noma kwesinye isikhathi uphuza utshwala obuningi ngesikhathi esifushane. Buza udokotela wakho mayelana nokusetshenziswa okuphephile kweziphuzo ezidakayo ngenkathi uthatha i-eluxadoline. Ukuphuza utshwala kungakhuphula ubungozi bokuthi uzoba ne-pancreatitis.

Ngaphandle kokuthi udokotela wakho akutshele ngenye indlela, qhubeka nokudla okuvamile.

Thatha umthamo ongabanjwanga ngokushesha nje lapho uwukhumbula ngokudla. Kodwa-ke, uma sekuyisikhathi somthamo olandelayo, weqa umthamo ongabanjwanga bese uqhubeka neshejuli yakho ejwayelekile yokulinganisa. Ungathathi umthamo ophindwe kabili ukwenza okulahlekile.

I-Eluxadoline ingadala imiphumela emibi. Tshela udokotela wakho uma kukhona kulezi zimpawu ezinzima noma ezingapheli:

• isicanucanu
• ukuhlanza

Eminye imiphumela emibi ingaba mibi. Uma uhlangabezana nenye yalezi zimpawu, yeka ukuthatha i-eluxadoline bese ushayela udokotela wakho ngokushesha noma uthole ukwelashwa okuphuthumayo:

• ubuhlungu obuqala endaweni engaphezulu yesisu kepha bungasabalala buye emhlane noma ehlombe ngesicanucanu noma ngaphandle kokuhlanza
• ukuqunjelwa okukhulu
• ukuqubuka; isifuba; ukuvuvukala ubuso noma umphimbo; ukuphelelwa umoya; ukuqina komphimbo; ubuhlungu besifuba noma ukuqina; noma ubunzima bokugwinya noma ukuphefumula

I-Eluxadoline ingadala eminye imiphumela emibi. Shayela udokotela wakho uma unezinkinga ezingavamile ngenkathi uthatha lo muthi.

Uma uthola imiphumela emibi kakhulu, wena noma udokotela wakho ungathumela umbiko kuhlelo lwe-Food and Drug Administration's (FDA) MedWatch Adverse Event Reporting online (http://www.fda.gov/Safety/MedWatch) noma ngocingo ( 1-800-332-1088).

Gcina le mithi esitsheni efike ngayo, ivalwe ngokuqinile, futhi lapho izingane zingafinyeleleki khona. Gcina ekamelweni lokushisa futhi kude nokushisa okweqile nomswakama (hhayi endlini yangasese).

Kubalulekile ukugcina yonke imishanguzo ingabonakali futhi ifinyeleleke ezinganeni njengoba iziqukathi eziningi (njengezingqondo zamaphilisi zamasonto onke kanye nalawo amaconsi wamehlo, okhilimu, amabala, kanye nama-inhalers) azimeleki ezinganeni futhi izingane ezincane zingazivula kalula. Ukuvikela izingane ezisencane ekufakeni ubuthi, hlala uvala amakepisi okuphepha bese ubeka umuthi endaweni ephephile - eyodwa ephezulu futhi engekho futhi engabonakali kubo futhi efinyelela kuyo. http://www.upandaway.org

Imithi engadingeki kufanele ilahlwe ngezindlela ezikhethekile zokuqinisekisa ukuthi izilwane ezifuywayo, izingane nabanye abantu abakwazi ukuzidla. Kodwa-ke, akufanele ukhiphe le mithi ethoyilethi. Esikhundleni salokho, indlela engcono kakhulu yokulahla imithi yakho ngohlelo lokubuyisa umuthi. Khuluma nosokhemisi wakho noma uthinte umnyango wangakini wokulahla udoti / wokusebenzisa kabusha ukuze ufunde ngezinhlelo zokubuyisa emphakathini wakho. Bheka iwebhusayithi yakwa-FDA's Safe Disposal of Medicines (http://goo.gl/c4Rm4p) ukuthola eminye imininingwane uma ungakwazi ukufinyelela kuhlelo lokubuyisa.

Uma kwenzeka ukweqisa ngokweqile, shayela ucingo losizo lokulawula ubuthi ku-1-800-222-1222. Imininingwane iyatholakala online ku-https: //www.poisonhelp.org/help. Uma isisulu siwile, saba nokuquleka, sinenkinga yokuphefumula, noma singakwazi ukuvuswa, shayela ngokushesha abezimo eziphuthumayo ku-911.

Gcina wonke ama-aphoyintimenti nodokotela wakho.

Ungavumeli omunye umuntu ukuthi athathe imithi yakho. I-Eluxadoline yinto elawulwayo. Okubhalwe phansi kungagcwaliswa izikhathi ezimbalwa kuphela; buza usokhemisi wakho uma unemibuzo.

Kubalulekile ukuthi ugcine uhlu olubhaliwe lwayo yonke imishanguzo oyisebenzisayo kadokotela kanye nokungabhaliswanga (ngaphezulu kokuthenga), kanye nanoma yimiphi imikhiqizo efana namavithamini, amaminerali, noma ezinye izithako zokudla. Kufanele uze nalolu hlu njalo uma uvakashela udokotela noma uma ungeniswa esibhedlela. Kubaluleke kakhulu futhi nemininingwane ebalulekile ukuthi uphathe uma kwenzeka kunezimo eziphuthumayo.

• IViberzi^®