Alectinib

-Delile

• Ngaphambi kokuthatha i-alectinib,
• I-Alectinib ingadala imiphumela emibi. Tshela udokotela wakho uma kukhona kulezi zimpawu ezinzima noma ezingapheli:
• Eminye imiphumela emibi ingaba mibi. Uma uhlangabezana nanoma yiziphi zalezi zimpawu noma lezo ezisohlwini lwe-SPECIAL PRECAUTIONS section, shayela udokotela wakho ngokushesha:

I-Alectinib isetshenziselwa ukwelapha uhlobo oluthile lomdlavuza wamaphaphu ongelona elincane (i-NSCLC) osabalalele kwezinye izingxenye zomzimba. I-Alectinib isekilasini lemithi ebizwa nge-kinase inhibitors. Isebenza ngokuvimba isenzo sephrotheni engavamile ekhombisa ukuthi amangqamuzana omdlavuza ayanda. Lokhu kusiza ukunciphisa noma ukumisa ukusabalala kwamangqamuzana omdlavuza.

I-Alectinib iza njengephilisi elizothathwa ngomlomo. Imvamisa kuthathwa ngokudla kabili ngosuku. Thatha i-alectinib ngasikhathi sinye nsuku zonke. Landela izinkomba ezikulebuli kadokotela wakho ngokucophelela, bese ubuza udokotela noma usokhemisi wakho ukuthi akuchaze nganoma iyiphi ingxenye ongayiqondi. Thatha i-alectinib njengoba iqondisiwe. Ungayithathi kancane noma uyithathe kaningi kunokuyalelwa ngudokotela wakho.

Gwinya wonke amaphilisi; ungazivuli noma uzichithe.

Uma uhlanza ngemuva kokuthatha i-alectinib, ungathathi ngokushesha omunye umthamo. Qhubeka nesimiso sakho sokulinganisa okuvamile.

Udokotela wakho angayeka ukwelashwa kwakho okwesikhashana noma unomphela noma anciphise umthamo wakho uma uhlangabezana nemiphumela ethile emibi ye-alectinib. Tshela udokotela wakho ukuthi uzizwa kanjani ngenkathi welashwa. Qhubeka uthathe i-alectinib noma ngabe uzizwa uphilile. Ungayeki ukuthatha i-alectinib ngaphandle kokukhuluma nodokotela wakho.

Buza usokhemisi noma udokotela wakho ikhophi lemininingwane yomkhiqizi yesiguli.

Lo muthi ungabekelwa okunye ukusetshenziswa; buza udokotela wakho noma usokhemisi ukuthola eminye imininingwane.

Ngaphambi kokuthatha i-alectinib,

• Tshela udokotela wakho kanye nosokhemisi uma unegciwane ku-alectinib, noma imuphi omunye umuthi, noma iziphi izithako kuma-capsule alectinib. Buza usokhemisi wakho ukuthola uhlu lwezithako.
• Tshela udokotela wakho kanye nosokhemisi ukuthi imiphi eminye imishanguzo kadokotela neyokungabhalisi, amavithamini, izithasiselo zokudla okunempilo, nemikhiqizo yamakhambi oyithathayo noma ohlela ukuyithatha. Qiniseka ukuthi usho noma ikuphi kokulandelayo: imithi yokwelapha umfutho wegazi ophakeme noma izinkinga zenhliziyo. Udokotela wakho angadinga ukushintsha imithamo yemithi yakho noma akuqaphele ngokucophelela ngemiphumela emibi.
• utshele udokotela wakho uma uke waba nesifo sesibindi, amaphaphu noma izinkinga zokuphefumula, noma ukushaya kwenhliziyo okuhamba kancane noma okungajwayelekile.
• tshela udokotela wakho uma ukhulelwe noma uhlela ukukhulelwa, noma uma uhlela ukuba nobaba wengane. Akufanele ukhulelwe ngenkathi uthatha i-alectinib. Uma ungowesifazane, kufanele usebenzise indlela ethembekile yokulawula ukuzalwa ngenkathi uthatha i-alectinib futhi okungenani isonto elilodwa ngemuva komthamo wakho wokugcina. Uma ungowesilisa, wena nomlingani wakho wesifazane kufanele nisebenzise ukulawulwa kokubeletha okusebenzayo ngenkathi nithatha i-alectinib nezinyanga ezintathu ngemuva komthamo wakho wokugcina. Uma wena noma umlingani wakho ukhulelwa ngenkathi uthatha i-alectinib shayela udokotela wakho ngokushesha. I-Alectinib ingalimaza umbungu.
• tshela udokotela wakho uma uncelisa. Akufanele uncelise ibele ngenkathi uthatha i-alectinib kanye neviki elingu-1 ngemuva komthamo wakho wokugcina.
• uhlela ukugwema ukuvezwa ukukhanya kwelanga okungadingekile noma isikhathi eside (kufaka phakathi izibani zelanga nemibhede yokushuka) nokugqoka izingubo zokuzivikela, izibuko zelanga, kanye nesigcino selanga esinokuvikela ilanga (SPF) lokungenani okungama-50 ngenkathi uthatha i-alectinib futhi okungenani izinsuku eziyi-7 ngemuva umthamo wakho wokugcina. I-Alectinib ingenza isikhumba sakho sizwele ekukhanyeni kwelanga.

Ngaphandle kokuthi udokotela wakho akutshele ngenye indlela, qhubeka nokudla okuvamile.

Yeqa umthamo ophuthelwe bese uqhubeka nesimiso sakho sokulinganisa esivamile. Ungathathi umthamo ophindwe kabili ukwenza okulahlekile.

I-Alectinib ingadala imiphumela emibi. Tshela udokotela wakho uma kukhona kulezi zimpawu ezinzima noma ezingapheli:

• ukuqunjelwa
• isifo sohudo
• ukuvuvukala ezandleni zakho, ubuso, noma izinkophe
• ikhanda
• ukuzuza kwesisindo
• ukuqubuka

Eminye imiphumela emibi ingaba mibi. Uma uhlangabezana nanoma yiziphi zalezi zimpawu noma lezo ezisohlwini lwe-SPECIAL PRECAUTIONS section, shayela udokotela wakho ngokushesha:

• ukuphefumula okusha noma okuya kuba kubi, ukuphefumula kanzima, noma ukukhwehlela
• imfiva
• ubuhlungu besifuba obungazelelwe
• isiyezi, ikhanda elikhanyayo, noma ukuquleka
• umbono uyashintsha
• ubuhlungu bemisipha obungazelelwe, ubumnene, noma ubuthakathaka
• ukuhlungu obusemhlane
• ukukhathala
• ukuqubuka
• isikhumba esilumayo
• ukulahlekelwa isifiso sokudla
• isicanucanu
• ukuhlanza
• ukuphuzi kwesikhumba noma okumhlophe kwamehlo akho
• ubuhlungu ohlangothini lokunene lwesisu sakho
• shintsha inani noma umbala womchamo wakho
• ukuvuvukala okusha noma okukhulayo emilenzeni nasezinyaweni zakho
• ukopha noma ukulimaza kalula kunokujwayelekile

I-Alectinib ingadala eminye imiphumela emibi. Shayela udokotela wakho uma unezinkinga ezingavamile ngenkathi uthatha lo muthi.

Uma uthola imiphumela emibi kakhulu, wena noma udokotela wakho ungathumela umbiko kuhlelo lwe-Food and Drug Administration's (FDA) MedWatch Adverse Event Reporting online (http://www.fda.gov/Safety/MedWatch) noma ngocingo ( 1-800-332-1088).

Gcina le mithi esitsheni efike ngayo, ivalwe ngokuqinile, futhi lapho izingane zingafinyeleleki khona. Ukugcine ekamelweni lokushisa kude nokukhanya, ukushisa okweqile nomswakama (hhayi endlini yangasese).

Imithi engadingeki kufanele ilahlwe ngezindlela ezikhethekile zokuqinisekisa ukuthi izilwane ezifuywayo, izingane nabanye abantu abakwazi ukuzidla. Kodwa-ke, akufanele ukhiphe le mithi ethoyilethi. Esikhundleni salokho, indlela engcono kakhulu yokulahla imithi yakho ngohlelo lokubuyisa umuthi. Khuluma nosokhemisi wakho noma uthinte umnyango wangakini wokulahla udoti / wokusebenzisa kabusha ukuze ufunde ngezinhlelo zokubuyisa emphakathini wakho. Bheka iwebhusayithi yakwa-FDA's Safe Disposal of Medicines (http://goo.gl/c4Rm4p) ukuthola eminye imininingwane uma ungakwazi ukufinyelela kuhlelo lokubuyisa.

Kubalulekile ukugcina yonke imishanguzo ingabonakali futhi ifinyeleleke ezinganeni njengoba iziqukathi eziningi (njengezingqondo zamaphilisi zamasonto onke kanye nalawo amaconsi wamehlo, okhilimu, amabala, kanye nama-inhalers) azimeleki ezinganeni futhi izingane ezincane zingazivula kalula. Ukuvikela izingane ezisencane ekufakeni ubuthi, hlala uvala amakepisi okuphepha bese ubeka umuthi endaweni ephephile - eyodwa ephezulu futhi engekho futhi engabonakali kubo futhi efinyelela kuyo. http://www.upandaway.org

Uma kwenzeka ukweqisa ngokweqile, shayela ucingo losizo lokulawula ubuthi ku-1-800-222-1222. Imininingwane iyatholakala online ku-https: //www.poisonhelp.org/help. Uma isisulu siwile, saba nokuquleka, sinenkinga yokuphefumula, noma singakwazi ukuvuswa, shayela ngokushesha abezimo eziphuthumayo ku-911.

Gcina wonke ama-aphoyintimenti nodokotela wakho kanye nelabhorethri. Udokotela wakho uzohlola izinga lokushaya kwenhliziyo yakho nomfutho wegazi njalo bese e-oda izivivinyo ezithile zebhu ukuze ahlole impendulo yomzimba wakho ku-alectinib.

Ungavumeli omunye umuntu ukuthi athathe imithi yakho. Buza usokhemisi wakho noma imiphi imibuzo onayo mayelana nokugcwalisa umuthi wakho.

Kubalulekile ukuthi ugcine uhlu olubhaliwe lwayo yonke imishanguzo oyisebenzisayo kadokotela kanye nokungabhaliswanga (ngaphezulu kokuthenga), kanye nanoma yimiphi imikhiqizo efana namavithamini, amaminerali, noma ezinye izithako zokudla. Kufanele uze nalolu hlu njalo uma uvakashela udokotela noma uma ungeniswa esibhedlela. Kubaluleke kakhulu futhi nemininingwane ebalulekile ukuthi uphathe uma kwenzeka kunezimo eziphuthumayo.

• U-Alecensa^®