Imethylnaltrexone

-Delile

• Ngaphambi kokuthatha i-methylnaltrexone,
• IMethylnaltrexone ingadala imiphumela emibi. Tshela udokotela wakho uma kukhona kulezi zimpawu ezinzima noma ezingapheli:
• Eminye imiphumela emibi ingaba mibi. Uma uhlangabezana nenye yalezi zimpawu, yeka ukuthatha i-methylnaltrexone bese ushayela udokotela wakho ngokushesha:
• Izimpawu zokudlula ngokweqile zingafaka okulandelayo:

IMethylnaltrexone isetshenziselwa ukwelapha ukuqunjelwa okubangelwa yimithi yezinhlungu i-opioid (narcotic) kubantu abanezinhlungu ezingapheli (eziqhubekayo) ezingabangelwa ngumdlavuza kepha kungenzeka zihlobene nomdlavuza owedlule noma ukwelashwa komdlavuza. IMethylnaltrexone isekilasini lemithi ebizwa ngokuthi yi-peripherally acting mu-opioid receptor antagonists. Isebenza ngokuvikela amathumbu emiphumeleni yemithi ye-opioid (narcotic).

IMethylnaltrexone iza njengethebhulethi ezothathwa ngomlomo. Imvamisa kuthathwa kanye ngosuku ngamanzi, okungenani imizuzu engama-30 ngaphambi kokudla kokuqala kosuku. Thatha i-methylnaltrexone ngasikhathi sinye nsuku zonke. Landela izinkomba ezikulebuli kadokotela wakho ngokucophelela, bese ubuza udokotela noma usokhemisi wakho ukuthi akuchaze nganoma iyiphi ingxenye ongayiqondi. Thatha i-methylnaltrexone njengoba iqondisiwe. Ungayithathi kancane noma uyithathe kaningi kunokuyalelwa ngudokotela wakho.

IMethylnaltrexone izothathwa ngabantu abathatha imishanguzo ye-opioid (narcotic). Khuluma nodokotela wakho uma ushintsha ukuthi uyiphuza kangakanani noma kangaki imithi yakho ye-opioid. Uma uyeka ukuthatha imishanguzo ye-opioid, kufanele futhi uyeke ukuthatha i-methylnaltrexone.

Kufanele uyeke ukuthatha eminye imithi ye-laxative lapho uqala ukuthatha i-methylnaltrexone. Kodwa-ke, qiniseka ukuthi wazise udokotela wakho uma i-methylnaltrexone ingakusebenzeli ngemuva kokuyithatha izinsuku ezintathu. Udokotela wakho angakutshela ukuthi uthathe eminye imithi yokwelapha i-laxative.

Udokotela wakho noma usokhemisi uzokunikeza ishidi lemininingwane yesiguli lomkhiqizi (Umhlahlandlela Wezokwelapha) lapho uqala ukwelashwa nge-methylnaltrexone futhi isikhathi ngasinye lapho ugcwalisa umuthi wakho. Funda imininingwane ngokucophelela bese ubuza udokotela noma usokhemisi wakho uma unemibuzo. Ungavakashela futhi iwebhusayithi ye-Food and Drug Administration (FDA) (http://www.fda.gov/Drugs/DrugSafety/ucm085729.htm) ukuthola uMhlahlandlela Wezokwelapha.

Lo muthi ungabekelwa okunye ukusetshenziswa; buza udokotela wakho noma usokhemisi ukuthola eminye imininingwane.

Ngaphambi kokuthatha i-methylnaltrexone,

• Tshela udokotela kanye nosokhemisi wakho uma unegciwane ku-methylnaltrexone, noma imiphi eminye imithi, noma iziphi izithako ezikumaphilisi e-methylnaltrexone. Buza usokhemisi wakho noma uhlole Umhlahlandlela Wezokwelapha ukuthola uhlu lwezithako.
• Tshela udokotela wakho kanye nosokhemisi ukuthi imiphi imishanguzo kadokotela neyokungabhalisi, amavithamini, izithako zokudla okunempilo, nemikhiqizo yamakhambi oyithathayo noma ohlela ukuyithatha. Qiniseka ukuthi usho noma yikuphi okulandelayo: Udokotela wakho angadinga ukushintsha imithamo yemithi yakho noma akuqaphele ngokucophelela ngemiphumela emibi.
• Tshela udokotela wakho uma uke waba nokuthinteka kwamathumbu noma wake waba nokuvaleka emathunjini akho. Udokotela wakho mhlawumbe uzokutshela ukuthi ungathathi i-methylnaltrexone.
• Tshela udokotela wakho uma uke waba nezinkinga zesisu noma zamathumbu kubandakanya isilonda esiswini (izilonda esiswini sesisu), umdlavuza wesisu noma wamathumbu, isifo sikaCrohn (isimo lapho umzimba uhlasela ulwelwesi lwendlela yokugaya ukudla , kubangela ubuhlungu, isifo sohudo, ukwehla kwesisindo, kanye nomkhuhlane), i-diverticulitis (izikhwama ezincane emgqeni wamathumbu amakhulu angavuvukala), i-Ogilvie's syndrome (isimo lapho kukhona khona ukuqhuma emathunjini), noma izinso noma isibindi isifo.
• Tshela udokotela wakho uma ukhulelwe noma uhlela ukukhulelwa Uma ukhulelwa ngenkathi uthatha i-methylnaltrexone, shayela udokotela wakho. Uma uthatha i-methylnaltrexone ngesikhathi ukhulelwe, ingane yakho ingathola izimpawu zokuhoxa kwe-opioid.
• tshela udokotela wakho uma uncelisa. Ungancelisi ibele ngenkathi uthatha i-methylnaltrexone.
• kufanele wazi ukuthi iningi labantu linokuhamba kwamathumbu kungakapheli imizuzu embalwa kuya emahoreni ambalwa ngemuva kokuthatha i-methylnaltrexone. Qiniseka ukuthi useduze nendlu yangasese lapho uphuza lo muthi.

Ngaphandle kokuthi udokotela wakho akutshele ngenye indlela, qhubeka nokudla okuvamile.

Yeqa umthamo ophuthelwe bese uqhubeka nesimiso sakho sokulinganisa esivamile. Ungathathi umthamo ophindwe kabili ukwenza okulahlekile.

IMethylnaltrexone ingadala imiphumela emibi. Tshela udokotela wakho uma kukhona kulezi zimpawu ezinzima noma ezingapheli:

• ukuhlanza
• ukujuluka
• Ukugodola
• ukukhathazeka
• kuzamula
• ikhanda
• ubuhlungu besisu nokuvuvukala
• ukuphazamiseka kwemisipha
• ikhala eligijimayo

Eminye imiphumela emibi ingaba mibi. Uma uhlangabezana nenye yalezi zimpawu, yeka ukuthatha i-methylnaltrexone bese ushayela udokotela wakho ngokushesha:

• isifo sohudo esibi
• ubuhlungu obukhulu besisu

IMethylnaltrexone ingadala eminye imiphumela emibi. Shayela udokotela wakho uma unezinkinga ezingavamile ngenkathi uthatha lo muthi.

Uma uthola imiphumela emibi kakhulu, wena noma udokotela wakho ungathumela umbiko kuhlelo lwe-Food and Drug Administration's (FDA) MedWatch Adverse Event Reporting online (http://www.fda.gov/Safety/MedWatch) noma ngocingo ( 1-800-332-1088).

Gcina le mithi esitsheni efike ngayo, ivalwe ngokuqinile, futhi lapho izingane zingafinyeleleki khona. Gcina ekamelweni lokushisa futhi kude nokushisa okweqile nomswakama (hhayi endlini yangasese). Uma umuthi wakho ufike ne-desiccant canister (ibhokisana elincane eliqukethe into edonsa umswakama ukugcina umuthi womile), shiya ibhokisana eliyibhokisi ebhodleleni.

Kubalulekile ukugcina yonke imishanguzo ingabonakali futhi ifinyeleleke ezinganeni njengoba iziqukathi eziningi (njengezingqondo zamaphilisi zamasonto onke kanye nalawo amaconsi wamehlo, okhilimu, amabala, kanye nama-inhalers) azimeleki ezinganeni futhi izingane ezincane zingazivula kalula. Ukuvikela izingane ezisencane ekufakeni ubuthi, hlala uvala amakepisi okuphepha bese ubeka umuthi endaweni ephephile - eyodwa ephezulu futhi engekho futhi engabonakali kubo futhi efinyelela kuyo. http://www.upandaway.org

Imithi engadingeki kufanele ilahlwe ngezindlela ezikhethekile zokuqinisekisa ukuthi izilwane ezifuywayo, izingane nabanye abantu abakwazi ukuzidla. Kodwa-ke, akufanele ukhiphe le mithi ethoyilethi. Esikhundleni salokho, indlela engcono kakhulu yokulahla imithi yakho ngohlelo lokubuyisa umuthi. Khuluma nosokhemisi wakho noma uthinte umnyango wangakini wokulahla udoti / wokusebenzisa kabusha ukuze ufunde ngezinhlelo zokubuyisa emphakathini wakho. Bheka iwebhusayithi yakwa-FDA's Safe Disposal of Medicines (http://goo.gl/c4Rm4p) ukuthola eminye imininingwane uma ungakwazi ukufinyelela kuhlelo lokubuyisa.

Uma kwenzeka ukweqisa ngokweqile, shayela ucingo losizo lokulawula ubuthi ku-1-800-222-1222. Imininingwane iyatholakala online ku-https: //www.poisonhelp.org/help. Uma isisulu siwile, saba nokuquleka, sinenkinga yokuphefumula, noma singakwazi ukuvuswa, shayela ngokushesha abezimo eziphuthumayo ku-911.

Izimpawu zokudlula ngokweqile zingafaka okulandelayo:

• isiyezi, ikhanda elikhanyayo, nokuquleka lapho uvuka ngokushesha okukhulu endaweni yokulala
• Ukugodola
• ukujuluka
• ikhala eligijimayo
• isifo sohudo
• ubuhlungu besisu
• ukukhathazeka
• kuzamula
• ukwehla kwemiphumela yokudambisa izinhlungu yemithi ye-opioid

Gcina wonke ama-aphoyintimenti nodokotela wakho.

Ungavumeli omunye umuntu ukuthi athathe imithi yakho. Buza usokhemisi wakho noma imiphi imibuzo onayo mayelana nokugcwalisa umuthi wakho.

Kubalulekile ukuthi ugcine uhlu olubhaliwe lwayo yonke imishanguzo oyisebenzisayo kadokotela kanye nokungabhaliswanga (ngaphezulu kokuthenga), kanye nanoma yimiphi imikhiqizo efana namavithamini, amaminerali, noma ezinye izithako zokudla. Kufanele uze nalolu hlu njalo uma uvakashela udokotela noma uma ungeniswa esibhedlela. Kubaluleke kakhulu futhi nemininingwane ebalulekile ukuthi uphathe uma kwenzeka kunezimo eziphuthumayo.

• Ohambisanayo^®