I-Naldemedine

-Delile

• Ngaphambi kokuthatha i-naldemedine,
• I-Naldemedine ingadala imiphumela emibi. Tshela udokotela wakho uma kukhona kulezi zimpawu ezinzima noma ezingapheli:
• Eminye imiphumela emibi ingaba mibi. Uma uhlangabezana nenye yalezi zimpawu, yeka ukuthatha i-naldemedine bese ushayela udokotela wakho ngokushesha noma uthole ukwelashwa okuphuthumayo:
• Izimpawu zokudlula ngokweqile zingafaka okulandelayo:

I-Naldemedine isetshenziselwa ukwelapha ukuqunjelwa okubangelwa yimithi yezinhlungu i-opioid (narcotic) kubantu abadala abanezinhlungu ezingapheli (eziqhubekayo) ezingabangelwa umdlavuza. INaldemedine isekilasini lemithi ebizwa ngokuthi i-peripherally acting mu-opioid receptor antagonists. Isebenza ngokuvikela amathumbu emiphumeleni yemithi ye-opioid (narcotic).

INaldemedine iza njengethebhulethi yokuphuza ngomlomo. Imvamisa kuthathwa kanye ngosuku, noma ngaphandle kokudla. Thatha i-naldemedine ngasikhathi sinye nsuku zonke. Landela izinkomba ezikulebuli kadokotela wakho ngokucophelela, bese ubuza udokotela noma usokhemisi wakho ukuthi akuchaze nganoma iyiphi ingxenye ongayiqondi. Thatha i-naldemedine njengoba nje kuqondisiwe. Ungayithathi kancane noma uyithathe kaningi kunokuyalelwa ngudokotela wakho.

Tshela udokotela wakho uma uyeka ukuthatha imishanguzo ye-opioid. Uma uyeka ukuthatha imishanguzo ye-opioid, kufanele futhi uyeke ukuthatha i-naldemedine futhi.

Udokotela wakho noma usokhemisi uzokunikeza ishidi lemininingwane yesiguli lomkhiqizi (Umhlahlandlela Wezokwelapha) lapho uqala ukwelashwa nge-naldemedine futhi isikhathi ngasinye lapho ugcwalisa umuthi wakho. Funda imininingwane ngokucophelela bese ubuza udokotela noma usokhemisi wakho uma unemibuzo. Ungavakashela futhi iwebhusayithi ye-Food and Drug Administration (FDA) (http://www.fda.gov/Drugs/DrugSafety/ucm085729.htm) ukuthola uMhlahlandlela Wezokwelapha.

Lo muthi ungabekelwa okunye ukusetshenziswa; buza udokotela wakho noma usokhemisi ukuthola eminye imininingwane.

Ngaphambi kokuthatha i-naldemedine,

• Tshela udokotela kanye nosokhemisi wakho uma unegciwane ku-naldemedine, noma imuphi omunye umuthi, noma iziphi izithako ezikumaphilisi e-naldemedine. Buza usokhemisi wakho noma uhlole Umhlahlandlela Wezokwelapha ukuthola uhlu lwezithako.
• Tshela udokotela wakho kanye nosokhemisi ukuthi imiphi eminye imishanguzo kadokotela neyokungabhalisi, amavithamini, izithako zokudla okunomsoco, okwenzayo noma ohlela ukukuthatha. Qiniseka ukuthi usho noma ikuphi kokulandelayo: amiodarone (Cordarone); i-aprepitant (Hlela); atazanavir (Reyataz, e-Evotaz); i-captopril (uCapoten, eCapozide); carbamazepine (Tegretol); i-clarithromycin (i-Biaxin, ku-PrevPac); i-cyclosporine (Gengraf, Neoral, Sandimmune); i-diltiazem (iCardizem, iDilacor, iTiazac); i-efavirenz (e-Atripla, eSustiva); i-erythromycin (E.E.S., E-Mycin, Erythrocin); i-fluconazole (iDiflucan); itraconazole (Onmel, Sporonax); ketoconazole (Nizoral); abanye abaphikisana nama-opioid njenge-methylnaltrexone (Relistor), naloxegol (Movantik), naloxone (Evzio, eBunavail, eSuboxone, eZubsolv), noma naltrexone (Revia, e Contrave, e-Embeda, eVivitrol); i-phenytoin (iDilantin, Phenytek); i-quinidine; i-rifampin (iRifadin, eRifamate, iRifater, iRimactane); i-ritonavir (iNorvir, eKaletra, eTechnivie, eViekira); i-saquinavir (i-Invirase): noma i-verapamil (i-Calan, i-Covera, i-Isoptin, i-Verelan). Udokotela wakho angadinga ukushintsha imithamo yemithi yakho noma akuqaphele ngokucophelela ngemiphumela emibi. Eminye imishanguzo eminingi ingaxhumana ne-naldemedine, ngakho-ke qiniseka ukuthi utshela udokotela wakho ngayo yonke imithi oyiphuzayo, ngisho naleyo engabonakali kulolu hlu.
• utshele udokotela wakho ukuthi yimiphi imikhiqizo yamakhambi oyithathayo, ikakhulukazi i-quercetin neSt.
• Tshela udokotela wakho uma uke waba nokuthinteka kwamathumbu noma wake waba nokuvaleka emathunjini akho. Udokotela wakho mhlawumbe uzokutshela ukuthi ungathathi i-naldemedine.
• Tshela udokotela wakho uma uke waba nezinkinga zesisu noma zamathumbu kubandakanya isilonda esiswini (izilonda esiswini sesisu), umdlavuza wesisu noma wamathumbu, isifo sikaCrohn (isimo lapho umzimba uhlasela ulwelwesi lwendlela yokugaya ukudla , kubangela ubuhlungu, isifo sohudo, ukwehla kwesisindo, nomkhuhlane), i-diverticulitis (izikhwama ezincane ezisemgqeni wamathumbu amakhulu angavuvukala), noma i-Ogilvie's syndrome (isimo lapho kunesibindi khona emathunjini), noma isifo sesibindi .
• utshele udokotela wakho uma ukhulelwe, hlela ukukhulelwa, noma uncelisa. Uma ukhulelwa ngenkathi uthatha i-naldemedine, shayela udokotela wakho.

Ngaphandle kokuthi udokotela wakho akutshele ngenye indlela, qhubeka nokudla okuvamile.

Thatha umthamo ongabanjwanga ngokushesha nje lapho uwukhumbula. Kodwa-ke, uma sekuyisikhathi somthamo olandelayo, weqa umthamo ongabanjwanga bese uqhubeka neshejuli yakho ejwayelekile yokulinganisa. Ungathathi umthamo ophindwe kabili ukwenza okulahlekile.

I-Naldemedine ingadala imiphumela emibi. Tshela udokotela wakho uma kukhona kulezi zimpawu ezinzima noma ezingapheli:

• ukuhlanza
• isifo sohudo
• isicanucanu
• ubuhlungu besisu
• ukujuluka
• Ukugodola
• ngizwe kubanda
• ukuqhuma
• imfiva
• amehlo anamanzi
• ikhala eligijimayo
• ukuthimula
• ukukhathazeka
• ukucasuka
• ukuzamazama okungalawuleki kwengxenye yomzimba
• ukushaya kwenhliziyo okusheshayo
• kuzamula

Eminye imiphumela emibi ingaba mibi. Uma uhlangabezana nenye yalezi zimpawu, yeka ukuthatha i-naldemedine bese ushayela udokotela wakho ngokushesha noma uthole ukwelashwa okuphuthumayo:

• ubuhlungu obukhulu besisu, obuphikelelayo, noma obubi
• ukuphefumula kanzima
• ukuqubuka

I-Naldemedine ingadala eminye imiphumela emibi.Shayela udokotela wakho uma unezinkinga ezingavamile ngenkathi uthatha lo muthi.

Uma uthola imiphumela emibi kakhulu, wena noma udokotela wakho ungathumela umbiko kuhlelo lwe-Food and Drug Administration's (FDA) MedWatch Adverse Event Reporting online (http://www.fda.gov/Safety/MedWatch) noma ngocingo ( 1-800-332-1088).

Gcina le mithi esitsheni efike ngayo, ivalwe ngokuqinile, futhi lapho izingane zingafinyeleleki khona. Ukugcine ekamelweni lokushisa kude nokukhanya, ukushisa okweqile nomswakama (hhayi endlini yangasese).

Gcina i-naldemedine endaweni ephephile ukuze kungabikho omunye umuntu ongayithatha ngephutha noma ngenhloso. Gcina umbhalo walokho ukuthi kushiywe amaphilisi amangaki ukuze wazi ukuthi kukhona yini okungekho.

Imithi engadingeki kufanele ilahlwe ngezindlela ezikhethekile zokuqinisekisa ukuthi izilwane ezifuywayo, izingane nabanye abantu abakwazi ukuzidla. Kodwa-ke, akufanele ukhiphe le mithi ethoyilethi. Esikhundleni salokho, indlela engcono kakhulu yokulahla imithi yakho ngohlelo lokubuyisa umuthi. Khuluma nosokhemisi wakho noma uthinte umnyango wangakini wokulahla udoti / wokusebenzisa kabusha ukuze ufunde ngezinhlelo zokubuyisa emphakathini wakho. Bheka iwebhusayithi yakwa-FDA's Safe Disposal of Medicines (http://goo.gl/c4Rm4p) ukuthola eminye imininingwane uma ungakwazi ukufinyelela kuhlelo lokubuyisa.

Kubalulekile ukugcina yonke imishanguzo ingabonakali futhi ifinyeleleke ezinganeni njengoba iziqukathi eziningi (njengezingqondo zamaphilisi zamasonto onke kanye nalawo amaconsi wamehlo, okhilimu, amabala, kanye nama-inhalers) azimeleki ezinganeni futhi izingane ezincane zingazivula kalula. Ukuvikela izingane ezisencane ekufakeni ubuthi, hlala uvala amakepisi okuphepha bese ubeka umuthi endaweni ephephile - eyodwa ephezulu futhi engekho futhi engabonakali kubo futhi efinyelela kuyo. http://www.upandaway.org

Uma kwenzeka ukweqisa ngokweqile, shayela ucingo losizo lokulawula ubuthi ku-1-800-222-1222. Imininingwane iyatholakala online ku-https: //www.poisonhelp.org/help. Uma isisulu siwile, saba nokuquleka, sinenkinga yokuphefumula, noma singakwazi ukuvuswa, shayela ngokushesha abezimo eziphuthumayo ku-911.

Izimpawu zokudlula ngokweqile zingafaka okulandelayo:

• Ukugodola
• ukujuluka
• isifo sohudo
• isicanucanu
• ukuhlanza
• ubuhlungu besisu
• isiyezi

Gcina wonke ama-aphoyintimenti nodokotela wakho.

Lo muthi awugcwaliseki kabusha. Qiniseka ukuthi uhlela ama-aphoyintimenti nodokotela wakho njalo ukuze ungaphelelwa yimithi.

Kubalulekile ukuthi ugcine uhlu olubhaliwe lwayo yonke imishanguzo oyisebenzisayo kadokotela kanye nokungabhaliswanga (ngaphezulu kokuthenga), kanye nanoma yimiphi imikhiqizo efana namavithamini, amaminerali, noma ezinye izithako zokudla. Kufanele uze nalolu hlu njalo uma uvakashela udokotela noma uma ungeniswa esibhedlela. Kubaluleke kakhulu futhi nemininingwane ebalulekile ukuthi uphathe uma kwenzeka kunezimo eziphuthumayo.

• I-Symproic^®

• I-Naldemedine Tosylate