Dacomitinib

-Delile

• Ngaphambi kokuthatha i-dacomitinib,
• I-Dacomitinib ingadala imiphumela emibi. Tshela udokotela wakho uma kukhona kulezi zimpawu ezinzima noma ezingapheli:
• Eminye imiphumela emibi ingaba mibi. Uma uhlangabezana nenye yalezi zimpawu, shayela udokotela wakho ngokushesha noma uthole ukwelashwa okuphuthumayo:

I-Dacomitinib isetshenziselwa ukwelapha uhlobo oluthile lomdlavuza wamaphaphu ongelona elincane (i-NSCLC) oselusabalalele kwezinye izitho zomzimba. UDacomitinib usesigabeni semithi ebizwa nge-kinase inhibitors. Isebenza ngokuvimba isenzo sephrotheni engavamile ekhombisa ukuthi amangqamuzana omdlavuza ayanda. Lokhu kusiza ukunciphisa noma ukumisa ukusabalala kwamangqamuzana omdlavuza.

UDacomitinib uza njengethebhulethi ezothathwa ngomlomo. Imvamisa kuthathwa kanye ngosuku noma ngaphandle kokudla. Thatha i-dacomitinib ngasikhathi sinye nsuku zonke. Landela izinkomba ezikulebuli kadokotela wakho ngokucophelela, bese ubuza udokotela noma usokhemisi wakho ukuthi akuchaze nganoma iyiphi ingxenye ongayiqondi. Thatha i-dacomitinib njengoba kushiwo. Ungayithathi kancane noma uyithathe kaningi kunokuyalelwa ngudokotela wakho.

Uma uhlanza ngemuva kokuthatha i-dacomitinib, ungathathi omunye umthamo ngokushesha. Qhubeka nesimiso sakho sokulinganisa okuvamile.

Udokotela wakho angamisa ukwelashwa kwakho okwesikhashana noma unomphela noma anciphise umthamo wakho uma uhlangabezana nemiphumela ethile emibi ye-dacomitinib. Tshela udokotela wakho ukuthi uzizwa kanjani ngenkathi welashwa. Qhubeka uthathe i-dacomitinib noma ngabe uzizwa uphilile. Ungayeki ukuthatha i-dacomitinib ngaphandle kokukhuluma nodokotela wakho.

Buza usokhemisi noma udokotela wakho ikhophi lemininingwane yomkhiqizi yesiguli.

Lo muthi ungabekelwa okunye ukusetshenziswa; buza udokotela wakho noma usokhemisi ukuthola eminye imininingwane.

Ngaphambi kokuthatha i-dacomitinib,

• Tshela udokotela wakho kanye nosokhemisi uma unegciwane ku-dacomitinib, noma imuphi omunye umuthi, noma yiziphi izithako ezibhebheni ze-dacomitinib. Buza usokhemisi wakho ukuthola uhlu lwezithako.
• Tshela udokotela wakho kanye nosokhemisi ukuthi imiphi eminye imishanguzo kadokotela neyokungabhalisi, amavithamini, izithasiselo zokudla okunempilo, nemikhiqizo yamakhambi oyithathayo noma ohlela ukuyithatha. Qiniseka ukuthi usho noma yikuphi okulandelayo: i-antidepressants efana ne-amitriptyline, clomipramine (Anafranil), desipramine (Norpramin), duloxetine (Cymbalta), fluoxetine (Prozac), imipramine (Tofranil), paroxetine (Paxil, Pexeva), ne-venlafaxine ); ama-antipsychotic afana ne-aripiprazole (Abilify), haloperidol (Haldol), risperidone (Risperdal), ne-thioridazine; i-atomoxetine (iStrattera); ama-beta blocker afana ne-carvedilol (Coreg), metoprolol (Dutoprol), ne-timolol; ikhodi; i-dextromethorphan (etholakala emithini eminingi yokukhwehlela; eNuedexta); i-flecainide (iTambocar); i-mexiletine; i-ondansetron (iZofran, iZuplenz); i-oxycodone (i-Oxaydo, i-Xtampza ER); i-propafenone (iRythmol SR); ama-proton-pump inhibitors afana ne-dexlanspoprazole (Dexilant), esomeprazole (Nexium), i-lansoprazole (Prevacid), i-omeprazole (Prilosec), i-pantoprazole (i-Protonix), ne-rabeprazole (i-AcipHex); i-tamoxifen (i-Soltamox); ne-tramadol (i-Conzip, i-Ultram). Udokotela wakho angadinga ukushintsha imithamo yemithi yakho noma akuqaphele ngokucophelela ngemiphumela emibi.
• uma uthatha umuthi we-indigestion, isilungulela, noma izilonda ezifana ne-cimetidine (Tagamet), i-famotidine (i-Pepcid, e-Duexis), i-nizatidine (i-Axid), noma i-ranitidine (i-Zantac), thatha i-dacomitinib okungenani amahora angu-6 ngaphambi noma okungenani i-10 amahora ngemuva kokuthatha owodwa wale mithi.
• Tshela udokotela wakho uma unezinhlungu ezivamile zohudo, isifo samaphaphu, izinkinga zokuphefumula ngaphandle komdlavuza wamaphaphu, noma isifo sesibindi noma sezinso.
• utshele udokotela wakho uma ukhulelwe noma uhlela ukukhulelwa. Kufanele uhlolwe ukukhulelwa ngaphambi kokuqala ukwelashwa. Akufanele ukhulelwe ngenkathi uthatha i-dacomitinib. Kufanele usebenzise indlela ethembekile yokulawula ukubeletha ngenkathi uthatha i-dacomitinib futhi okungenani izinsuku eziyi-17 ngemuva komthamo wakho wokugcina. Uma ukhulelwa ngenkathi uthatha i-dacomitinib, shayela udokotela wakho ngokushesha. I-Dacomitinib ingalimaza umbungu.
• tshela udokotela wakho uma uncelisa. Akufanele uncelise ngenkathi uthatha i-dacomitinib nezinsuku eziyi-17 ngemuva komthamo wakho wokugcina.
• uhlele ukusebenzisa i-moisturizer, ugweme ukuvezwa yilanga ngokungadingekile noma isikhathi eside, nokugqoka izingubo zokuzivikela, izibuko zelanga, kanye ne-sunscreen. IDacomitinib ingenza isikhumba sakho sizwele ekukhanyeni kwelanga.

Ngaphandle kokuthi udokotela wakho akutshele ngenye indlela, qhubeka nokudla okuvamile.

Yeqa umthamo ophuthelwe bese uqhubeka nesimiso sakho sokulinganisa esivamile. Ungathathi umthamo ophindwe kabili ukwenza okulahlekile.

I-Dacomitinib ingadala imiphumela emibi. Tshela udokotela wakho uma kukhona kulezi zimpawu ezinzima noma ezingapheli:

• ukuncipha komzimba
• ukulahlekelwa isifiso sokudla
• izilonda zomlomo
• ukutheleleka kwesikhumba ezungeze izinzipho noma izinzwani
• ukulahleka kwezinwele
• ukukhwehlela
• ukungabi namandla
• ubunzima bokulala noma ukulala
• amehlo abomvu noma avuvukile ("iso elibomvana")
• izinguquko zokunambitheka
• ukuhlanza

Eminye imiphumela emibi ingaba mibi. Uma uhlangabezana nenye yalezi zimpawu, shayela udokotela wakho ngokushesha noma uthole ukwelashwa okuphuthumayo:

• isifo sohudo
• ukuphefumula, ukukhwehlela, nomkhuhlane
• isikhumba esomile, ububomvu, ukuqubuka, induna, isikhumba esilumayo, nokuxebuka noma ukushwabana kwesikhumba sakho
• ubuhlungu besifuba

I-Dacomitinib ingadala eminye imiphumela emibi. Shayela udokotela wakho uma unezinkinga ezingavamile ngenkathi uthatha lo muthi.

Uma uthola imiphumela emibi kakhulu, wena noma udokotela wakho ungathumela umbiko kuhlelo lwe-Food and Drug Administration's (FDA) MedWatch Adverse Event Reporting online (http://www.fda.gov/Safety/MedWatch) noma ngocingo ( 1-800-332-1088).

Gcina le mithi esitsheni efike ngayo, ivalwe ngokuqinile, futhi lapho izingane zingafinyeleleki khona. Gcina ekamelweni lokushisa futhi kude nokushisa okweqile nomswakama (hhayi endlini yangasese).

Kubalulekile ukugcina yonke imishanguzo ingabonakali futhi ifinyeleleke ezinganeni njengoba iziqukathi eziningi (njengezingqondo zamaphilisi zamasonto onke kanye nalawo amaconsi wamehlo, okhilimu, amabala, kanye nama-inhalers) azimeleki ezinganeni futhi izingane ezincane zingazivula kalula. Ukuvikela izingane ezisencane ekufakeni ubuthi, hlala uvala amakepisi okuphepha bese ubeka umuthi endaweni ephephile - eyodwa ephezulu futhi engekho futhi engabonakali kubo futhi efinyelela kuyo. http://www.upandaway.org

Imithi engadingeki kufanele ilahlwe ngezindlela ezikhethekile zokuqinisekisa ukuthi izilwane ezifuywayo, izingane nabanye abantu abakwazi ukuzidla. Kodwa-ke, akufanele ukhiphe le mithi ethoyilethi. Esikhundleni salokho, indlela engcono kakhulu yokulahla imithi yakho ngohlelo lokubuyisa umuthi. Khuluma nosokhemisi wakho noma uthinte umnyango wangakini wokulahla udoti / wokusebenzisa kabusha ukuze ufunde ngezinhlelo zokubuyisa emphakathini wakho. Bheka iwebhusayithi yakwa-FDA's Safe Disposal of Medicines (http://goo.gl/c4Rm4p) ukuthola eminye imininingwane uma ungakwazi ukufinyelela kuhlelo lokubuyisa.

Uma kwenzeka ukweqisa ngokweqile, shayela ucingo losizo lokulawula ubuthi ku-1-800-222-1222. Imininingwane iyatholakala online ku-https: //www.poisonhelp.org/help. Uma isisulu siwile, saba nokuquleka, sinenkinga yokuphefumula, noma singakwazi ukuvuswa, shayela ngokushesha abezimo eziphuthumayo ku-911.

Gcina wonke ama-aphoyintimenti nodokotela wakho kanye nelabhorethri. Udokotela wakho uzoku-oda ukuhlolwa kwelebhu ngaphambi kokuba uqale ukwelashwa kwakho ukuze ubone ukuthi umdlavuza wakho ungelashwa nge-dacomitinib.

Ungavumeli omunye umuntu ukuthi athathe imithi yakho. Buza usokhemisi wakho noma imiphi imibuzo onayo mayelana nokugcwalisa umuthi wakho.

Kubalulekile ukuthi ugcine uhlu olubhaliwe lwayo yonke imishanguzo oyisebenzisayo kadokotela kanye nokungabhaliswanga (ngaphezulu kokuthenga), kanye nanoma yimiphi imikhiqizo efana namavithamini, amaminerali, noma ezinye izithako zokudla. Kufanele uze nalolu hlu njalo uma uvakashela udokotela noma uma ungeniswa esibhedlela. Kubaluleke kakhulu futhi nemininingwane ebalulekile ukuthi uphathe uma kwenzeka kunezimo eziphuthumayo.

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